establishment of the paradigm

... in the formation of retinal NV in the later stages of the OIR model In this study, we investigated the temporal and spatial distribution of microglial cells during the different stages of the ... retina, the mean number of microglial cells Page of from the three fields of each counting position (central or peripheral zone, and layer) was calculated Then, the mean and standard error of these ... expressed under the control of the Cx3cr1 promoter They are located in the vitreous (v) near the retina (see arrow heads in the cryosection) In contrast to the microglial cells, they have a larger...

Ngày tải lên: 19/06/2014, 22:20

... experience of diagnostic irradiation and/or radiotherapy for the treatment of germinomas, and through our review of the literature about the regression of germinomas [2-5], we have speculated that the ... confirmed the synchronous regression of the disseminated germinoma Prior to confirmation of the synchronous regression, it was estimated that the patient had received a dose of diagnostic radiation of ... reports the case of a 35-year-old man with a pineal germinoma who died unexpectedly of a massive pulmonary embolism on the eighth day of a course of radiation therapy after receiving a total dose of...

Ngày tải lên: 11/08/2014, 00:22

... and derangement of the epithelial lining (labeled E) half of the apoptotic eosinophils and at 24 h a majority of them exhibited secondary necrosis (Table 1) Typical signs of the secondary necrosis ... modes of cell death could thus be causally involved in the present aggravation of the allergic inflammation In view of the dependence of Fas-induced inflammation on established lung eosinophilia the ... interpretation of data and drafted the manuscript KRT performed the statistical analysis and participated in drawing the figures CGAP contributed to the design of the study and interpretation of in vivo...

Ngày tải lên: 12/08/2014, 18:22

... changes of the number of support vectors in the cases of both PASSIVE and M IN in Figure 11 and changes of the number of support vectors in the case of M OD S IMPLE in Figure 12 We observed that the ... consider the meaning of {j, i, “O”} if the head of the j-th bunsetsu is the k-th one such that j < k < i In the context of the algorithm in Figure 3, {j, i, “O”} actually means that the j-th ... some bunsetsu pair of the j-th bunsetsu and the i-th bunsetsu such that j < i The annotator is then asked what the head of the j-th bunsetsu is We define here the head bunsetsu is the k-th one We...

Ngày tải lên: 20/02/2014, 04:20

... David prefers to live in the country rather than in the city 2 Các bạn di chuột vào cụm từ để biết chức cụm câu: David prefers to live in the country rather than live in the city Tại câu lại dịch ... *David prefers to live in the country rather than live in the city Hình thức ngữ pháp : Cấu trúc “ prefer to something rather than (do) something else” – ( thích làm việc ... miền quê “in the city”- thành thị -“rather than”- là: Trong “ rather” trạng từ (abverb) có nghĩa là, thích …hơn “than” liên từ ( conjunction) có nghĩa hơn(để diễn đạt so sánh) Ở “ rather than”...

Ngày tải lên: 26/02/2014, 00:20

... majority of their online activity:   Nearly half of all 18-29 year olds (45%) who use the internet on their cell phones most of their online browsing on their mobile device Half (51%) of African-American ... from the 31% of cell owners who said that they used their phone to go online as recently as April 2009 Moreover, 31% of these current cell internet users say that they mostly go online using their ... of cell-mostly internet users mention factors related to convenience or the always-available nature of mobile phones when asked for the main reason why they most of their online browsing on their...

Ngày tải lên: 29/03/2014, 20:20

... in most of e-commercial Web applications The basket can be downloaded at the end of the session, under the form of a zip file containing all the datasets selected by the user The table of results ... But the most important contribution of the dictionary is the identification of the genealogy (lineage) of NUTS which proves very useful for the harmonization of time-series data The result of ... assessing the thematic relevance and completeness of the dataset related to the studied topic In this phase, the thematic expert assesses whether the indicators and values present in the dataset...

Ngày tải lên: 30/03/2014, 22:20

... power) of the semi-ma jor axis of its orbit (or, in other words, of the "semi-major axis" of the ellipse, half of the distance across the widest part of the ellipse) These laws in turn lay the ... period of their variation Therefore, if one could determine the distance to a single Cepheid of a known period (subsequently determined in 3) , then measuring the brightness of other Cepheids of the ... superclusters of galaxies and then estimate the total density of such superclusters in the universe, we could then "weigh the universe, " including all the dark matter Then, using the equations of general...

Ngày tải lên: 05/06/2014, 11:24

... power) of the semi-major axis of its orbit (or, in other words, of the “semi-major axis” of the ellipse, half of the distance across the widest part of the ellipse) These laws in turn lay the basis ... of a known period (subsequently determined in 1913), then measuring the brightness of other Cepheids of the same period would allow one to determine the distance to these other stars! Since the ... superclusters of galaxies and then estimate the total density of such superclusters in the universe, we could then “weigh the universe,” including all the dark matter Then, using the equations of general...

Ngày tải lên: 11/06/2014, 12:02

... lungs of Examples ofof individual mice Figure the spleens primary data of flow cytometry analysis of tetramer/pentamer+CD8+ and IFNγ+CD8+ cells from the lungs and Examples of primary data of flow ... local virus replication that results in the decreased functionality of CD8+ CTL in lungs, but rather the pulmonary site of residence of the cells Therefore, the conclusion that RSV infection specifically ... expressed the number of IFNγ+CD8+ cells as a percentage of the number of tetramer/pentamer+CD8+ cells (Figure 2) The resulting values confirmed the previous finding that tetramer+CD8+ CTL from the...

Ngày tải lên: 20/06/2014, 01:20

... after "rather than", you need to study the verb structures involved before "rather than" With practice and deeper understanding of the verb structures, you will soon learn how to apply the correct ... 2) Despite the risk of social isiolation,a problem occasionally seen in people who spend too much time at their computer rather than relating to to people in the real world, People ... to to people in the real world, People who spend too much time at their work rather than relating to people in the real work The verb structure is "to spend (time) doing something" To know when...

Ngày tải lên: 13/07/2014, 13:10

... and the local environment (c) There is some mixing of genes due to the dispersal of individuals between populations (represented as the individual dots making up the shaded areas) The level of ... outcomes are dependent on the interactions of the adaptations of both partners with the environment that they find themselves in Hence, the selection mosaic is a result of gene × gene × environment ... for the theory, but these have often been misunderstood It is not enough that the strength of coevolutionary selection varies between populations, it is also necessary that the direction of that...

Ngày tải lên: 06/08/2014, 18:21

... proteins was considered sufficient for determination of the presence of the antibody The presence of anti-SRP, anti-U3RNP and the rare anti-tRNA synthetases (anti-PL-7, anti-PL-12, anti-EJ, anti-OJ, ... DQB1*02 In light of this, a 'relative predispositional effect' test was performed to examine whether the effect of other alleles had been masked by the relatively increased frequency of these alleles ... prepare the manuscript WO oversaw the genotyping, contributed to interpretation of the findings and preparation of the manuscript RC set up AOMIC, oversaw the whole project and helped to prepare the...

Ngày tải lên: 09/08/2014, 07:20

... were blind to the treatment Each paw was graded according to the severity and extent of erythema and swelling of periarticular soft tissues, and the enlargement and distortion of the joints [32] ... group, data were further expressed as the area under the curve over the time course of the primary phase (days to 3) and the secondary phase (days to 17) of arthritis Assessment of proteoglycan metabolism ... representative sample of the whole joint Mean scores were determined from the different sections of the individual animals, allowing the calculation of composite scores for the different experimental...

Ngày tải lên: 09/08/2014, 10:22

... of the current study, the collection of data, did the statistical analyses and wrote the first draft of the paper and coordinated the writing process OAA, KS and IM participated in planning of ... Research Council of Norway (167153/V50; 164778/V50) The funding source had no involvement in the authors’ work The authors thank the other members of the TOP Study group and the patients that ... weeks [13] There were no statistically significant differences among the levels of substance use (number of units of alcohol or number of incidences of use of non-alcoholic substances) the last...

Ngày tải lên: 11/08/2014, 16:22

... lives There was, as a result, some tension between the supporters of the program: the VCH, VANDU and the PHS The hard-line approach of the PHS was in direct contravention of the wishes of VCH ... needs that arise out of the context of addicts' real, and not imagined lives, where illness and the risk of it exist in the life world of the IDU rather than the clinic The program operates 24 ... available The valued collective knowledge of the peer workers is paramount to the success of the program They are the eyes and ears, the heart and soul, and are always willing to share their experiences...

Ngày tải lên: 11/08/2014, 18:21

... (MAP) of 65 mmHg, 75 mmHg, and finally 85 mmHg The mean doses of norepinephrine required to maintain these MAPs were 23, 31 and 47 µg/min, respectively, whereas the mean heart rates at these ... vasopressor therapy [3] The cerebral perfusion pressure was found to be significantly lower for the same MAP while the patients were on dopamine The cerebral perfusion pressure increased from a mean of ... least partly due to their inability to cross the blood–brain barrier After severe brain injury, however, the blood–brain barrier may be locally disrupted and the autoregulation of cerebral blood...

Ngày tải lên: 12/08/2014, 19:21

... of a number of hormones from the anterior pituitary gland, including prolactin [3,4] However, if dopamine is used only for limited periods of time (as in shock resuscitation), then the deleterious ... not necessarily indicate that routine administration of dopamine is necessary to ‘protect the kidneys’, and indeed the use of renal doses of dopamine has recently been challenged [8] and can ... function in alveolar epithelial cells [10] If this is also the case in humans, then it could represent an important additional benefit of dopamine in critically ill patients, many of whom will be receiving...

Ngày tải lên: 12/08/2014, 19:21

... Central to the hypothesis that XMRV is a genuine human pathogen is the observation that it integrates into the chromosomal DNA of prostate tumour tissues [7,8] Such integration of the cDNA copy of genomic ... (PK) and the Medical Research Council (GJT, JAG) The funding sources had no role in study design; in the analysis and interpretation of data; in the writing of the manuscript; or in the decision ... (Figure 1B) These errors are possibly the result of somatic mutation in the cell line during its replication or the result of PCR error during amplification PCR error is not unlikely given the three...

Ngày tải lên: 13/08/2014, 01:20