epstein barr virus b cell infection

Báo cáo y học: "Effect of methotrexate and anti-TNF on Epstein-Barr virus T-cell response and viral load in patients with rheumatoid arthritis or spondylarthropathies" ppt

Ngày tải lên : 09/08/2014, 14:21

... Figure virus- specific T -cell response Correlation between the Epstein- Barr virus viral load and Epstein- Barr virus- specific T -cell response Correlation between the number of IFNγproducing T cells ... 496 AVLLHEESM B3 5 BZLF1 B3 5.01 EBNA1 EPLPQGQLTAY 407 to 417 HPVGEADYFEY B3 9 EBNA3C 271 to 278 HHIWQNLL B4 4 EBNA 3B 567 to 666 VEITPYKPTW B4 4.02 EBNA3C 281 to 290 EENLLDFVRF B4 4.02 EBNA3C 335 to ... of (page number not for citation purposes) gitudinal study Epstein- Barr virus load in peripheral blood mononuclear cells in the longitudinal study (a) Epstein- Barr virus (EBV) load between week...

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Báo cáo khoa học: Fast set-up of doxycycline-inducible protein expression in human cell lines with a single plasmid based on Epstein– Barr virus replication and the simple tetracycline repressor ppt

Ngày tải lên : 23/03/2014, 09:21

... symbol ETT ORCTL3 FLIPT1 EMT OCT1 SLC22A4 SLC22A13 SLC22A16 SLC22A3 SLC22A1 pEBTet pEBTet pEBTet pEBTet pEBTet OCT2 SLC22A2 pEBTet CAT4 SLC7A4 pEBTet pEBTetD pEBTetD pEBTetD be inﬂuenced by the ... (1985) Mapping genetic elements of Epstein Barr virus that facilitate extrachromosomal persistence of Epstein Barr virus- derived plasmids in human cells Mol Cell Biol 5, 2533–2542 Young JM, Cheadle ... infrequent, epigenetic event Mol Cell Biol 21, 4149–4161 Yates JL, Warren N & Sugden B (1985) Stable replication of plasmids derived from Epstein Barr virus in various mammalian cells Nature 313, 812–815...

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Báo cáo hóa học: " Secretion of Epstein-Barr Virus-encoded BARF1 oncoprotein from latently infected B cells" doc

Ngày tải lên : 20/06/2014, 01:20

... Okita K, Takada K: EpsteinBarr virus promotes epithelial cell growth in the absence of EBNA2 and LMP1 expression J Virol 1999, 73:1286-1292 Rickinson AB, Kieff E: Epstein- Barr Virus In Fields Virology ... established rodent cells Cell 1985, 43:831-840 Wei MX, Ooka T: A transforming fonction of the BARF1 gene encoded by Epstein- Barr Virus EMBO J 1989, 8:2897-2903 Hayes DP, Brink AA, Vervoort MB, ... activity of Epstein- Barr virus- encoded BARF1 protein Oncogene 2004, 23:4938-4944 Wang Li, Tam JP, Liu DX: Biochemical and functional characterization of Epstein- Barr virus- encoded BARF1 protein:...

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Báo cáo hóa học: " Quantitative profiling of housekeeping and Epstein-Barr virus gene transcription in Burkitt lymphoma cell lines using an oligonucleotide microarray" docx

Ngày tải lên : 20/06/2014, 01:20

... Gothoskar B: Sensitivity of Epstein- Barr virus (EBV) producer and non-producer human lymphoblastoid cell lines to superinfection with EB -virus Int J Cancer 1972, 10(1):44-57 Epstein MA, Achong BG, Barr ... some from lytic EBV infection (e.g., BZLF1/ Zta, BXLF2/gp85, BKRF2/gL and BZLF2/gp42) (Table 1B) We used B9 5.8 RNA as positive control and RNA from the EBV-negative BL cell line BJAB as a negative ... EBV-harboring BL cell lines The reference cell line B9 5.8 displays a latency III expression pattern, but about 5% of the cells display lytic EBV infection Thus, B9 5.8 is expected to transcribe...

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báo cáo khoa học: "Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report" docx

Ngày tải lên : 10/08/2014, 22:20

... HTLV-1: human T -cell lymphotropic virus type 1; HIV: human immunodeficiency virus; VCA: anti -Epstein- Barr virus- viral capsid antigen; EBNA: anti -Epstein- Barr virus nuclear antigen; LN: lymph node; ... with multilineage dysplasia; EBV: Epstein- Barr virus; T-LPD: T -cell lymphoproliferative disorder; WBC: white blood cell; CRP: C-reactive protein; ANA: anti-nuclear antibody; NSAIDs: anti-non steroid ... Blaese RM: Abnormally elevated frequency of Epstein- Barr virus- infected B cells in the blood of patients with rheumatoid arthritis J Clin Invest 1984, 73:1789-1795 Tosato G, Steinberg AD, Blaese RM:...

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Báo cáo y học: " Systemic Epstein-Barr-virus-positive T cell lymphoproliferative childhood disease in a 22-year-old Caucasian man: A case report and review of the literature" docx

Ngày tải lên : 10/08/2014, 23:21

... Shurin S, Abramowsky C, Tubbs RR, Sciotto CG, Wahl R, Sands J, Gottman D, Katz BZ, Sklar J: T -cell lymphomas containing Epstein- Barr viral DNA in patients with chronic Epstein- Barr virus infections ... Koizumi S: Differential cellular targets of Epstein- Barr virus (EBV) infection between acute EBV-associated hemophagocytic lymphohistiocytosis and chronic active EBV infection Blood 2001, 98:1882-1888 ... Fulminant EBV+ T cell LPD (phenotype: not reported) TCR -b EBV+, rearranged clonal nine/M Unspecified Hemophagocytic syndrome, FIM - Fulminant EBV+ T cell LPD (phenotype: not reported) TCR -b EBV+, rearranged...

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báo cáo khoa học: " Epstein Barr Virus-positive large T-cell lymphoma presenting as acute appendicitis 17 years after cadaveric renal transplant: a case report" docx

Ngày tải lên : 11/08/2014, 02:22

... putative role of EBV has been suggested in 89% of cases of B- cell PTLD [9], no direct role for this lymphotropic virus has been confirmed in T -cell PTLD EBV infects and immortalizes B cells causing ... unchecked proliferation of EBV-infected cells, as the critical T -cell control of B- cells is lacking in immunosuppressed patients [10] Human T -cell Lymphotropic Virus (HTLV1) has been reported to cause ... Monomorphic PTLD B- Cell Lymphomas Reactive Plasmacytic Hyperplasia Polyclonal Monoclonal T -Cell Lymphomas Other Types • Diffuse large B cell lymphoma • Burkitt/Burkitt-like lymphoma • Plasma cell myeloma...

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The development of an in vivo humanized mouse model to investigate epstein barr virus infection and tumorigenesis

Ngày tải lên : 10/09/2015, 09:22

... model of EBV infection Introduction Figure Epstein- Barr virus (EBV) life cycle Epstein- Barr virus (EBV) is transmitted by contact with the infected saliva The current concept holds that EBV invades ... Regulatory T cells xii CHAPTER : INTRODUCTION Humanized mouse model of EBV infection Introduction CHAPTER : INTRODUCTION 1.1 EPSTEIN- BARR VIRUS LIFE CYCLE Epstein- Barr Virus (EBV) is a ubiquitous ... link between Epstein- Barr virus infection of human B cells with lymphoproliferative disease and tumorigenesis viii LIST OF TABLES Table Latent EBV gene expression programs 17 Table EBV latency...

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epstein-barr virus protocols

Ngày tải lên : 10/04/2014, 22:31

... EBNA-LP LMP-2A LMP- 2B BZLF1 BRLF1 BARF transcripts EBNA-3 EBNA-4 EBNA-6 EBNA-5 TP-1 TP-2 ZEBRA, EB1, Zta Rta, R BART, CST EBNA, Epstein- Barr virus nuclear antigen; LMP, latent membrane protein; TP, ... Molecular Biology, Vol 174: Epstein- Barr Virus Protocols Edited by: J B Wilson and G H W May © Humana Press Inc., Totowa, NJ Farrell Table EBV Gene Nomenclature EBNA-3A EBNA- 3B EBNA-3C EBNA-LP LMP-2A ... the Epstein- Barr virus BamHI A fragment are detectable in all three forms of virus latency J Virol 67, 3182–3190 Sadler, R H and Raab-Traub, N (1995) Structural analyses of the Epstein- Barr virus...

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báo cáo hóa học:" Clinical values of multiple Epstein-Barr virus (EBV) serological biomarkers detected by xMAP technology" potx

Ngày tải lên : 18/06/2014, 15:20

... Rickinson AB, Kieff E: Epstein- Barr virus 4th edition Philadelphia (Pennsylvania): Lippincott/Williams & Wilkins; 2001 Crawford DH: Biology and disease associations of EpsteinBarr virus Philos ... CB, Murray PG: Epstein- Barr virus (EBV) and its associated human cancers – genetics, epigenetics, pathobiology and novel therapeutics Front Biosci 2006, 11:2672-2713 Kelly GL, Rickinson AB: Burkitt ... A, El Gueddari B, Joab I, Benslimane A, Khyatti M: Antibody responses to recombinant Epstein- Barr virus antigens in nasopharyngeal carcinoma patients: complementary test of ZEBRA protein and...

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Báo cáo hóa học: " Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinom" pot

Ngày tải lên : 18/06/2014, 16:20

... for 15 After h blocking in PBS + 0.1% Tween plus 1% bovine serum albumin, cells were incubated with primary antibodies of LMP1 (BD, USA), p-mTOR (Ser2448) and p-4EBP1 (Thr70) (Cell Signaling, ... of Epstein- Barr virus encoded latent membrane protein in the carcinogenesis of nasopharyngeal carcinoma Cellular & molecular immunology 2007, 4(3):185-196 Mainou BA, Everly DN Jr, Raab-Traub N: ... expression Cell culture and plasmids The EBV-negative human NPC cell lines HONE1 and 61 0B, and the EBV-positive NPC cell line C666-1 were incubated in RPMI-1640 medium supplemented with 10% fetal bovine...

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Báo cáo sinh học: "Epstein-barr virus induced cellular changes in nasal mucosa" pptx

Ngày tải lên : 19/06/2014, 08:20

... carcinoma cells to Epstein- Barr virus infection in vitro Laboratory Investigation 2000, 80(8):1149-60 Arrand JR, Rymo L: Characterization of the major Epstein- Barr virus- specific RNA in Burkitt ... carcinoma (NPC), or Epstein- Barr virus (EBV) [1012] The case described below focuses on specific microscopic and ultrastructural alterations in the nasal mucosal cells induced by EBV infection and ... multinuclear cells Electron6Microscopy (128.000×): Epstein- Barr Virus inside Electron Microscopy (128.000×): Epstein- Barr Virus inside multinuclear cells was the most specific method to investigate...

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báo cáo hóa học:"Epstein-barr virus induced cellular changes in nasal mucosa" docx

Ngày tải lên : 20/06/2014, 04:20

... carcinoma cells to Epstein- Barr virus infection in vitro Laboratory Investigation 2000, 80(8):1149-60 Arrand JR, Rymo L: Characterization of the major Epstein- Barr virus- specific RNA in Burkitt ... carcinoma (NPC), or Epstein- Barr virus (EBV) [1012] The case described below focuses on specific microscopic and ultrastructural alterations in the nasal mucosal cells induced by EBV infection and ... multinuclear cells Electron6Microscopy (128.000×): Epstein- Barr Virus inside Electron Microscopy (128.000×): Epstein- Barr Virus inside multinuclear cells was the most specific method to investigate...

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Báo cáo y học: "Patients with systemic lupus erythematosus have abnormally elevated Epstein–Barr virus load in blood" pps

Ngày tải lên : 09/08/2014, 01:23

... 100bp EBNA- 3B Type (125bp) 300bp 200bp Type (246bp) Type (153bp) Reconfirmation of the Epstein Barr virus (EBV) typing results The mouthwash samples were analyzed by PCR/Southern blot for EBV ... (54.5) EBV-negative (6.0) (1.5) Total 63 (100) 66 (100) EBV, Epstein Barr virus 11 10 Namalwa AG876 dH2O Marker Figure 300bp EBNA-2 Type (186bp) 200bp Type (168bp) 300bp EBNA-3C 200bp Type (149bp) ... induced by Epstein Barr virus infection Br J Dermatol 2002, 146:877-881 Tsai YT, Chiang BL, Kao YF, Hsieh KH: Detection of Epstein Barr virus and cytomegalovirus genome in white blood cells from...

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Báo cáo y học: "Epstein–Barr virus and rheumatoid arthritis: is there a link''''" docx

Ngày tải lên : 09/08/2014, 07:20

... interleukin-10 activity by Epstein- Barr virus protein BCRF1 Science 1990, 250:830-832 Cohen JI, Lekstrom K: Epstein- Barr virus BARF1 protein is dispensable for B- cell transformation and inhibits alpha interferon ... lymphocyte responses to Epstein- Barr virus infection Annu Rev Immunol 1997, 15:405-431 Cohen JI: Epstein- Barr virus infection N Engl J Med 2000, 343: 481-492 Kieff E: Epstein- Barr virus and its replication ... 81 82 83 84 85 Vol No Costenbader and Karlson responses to Epstein- Barr virus- determined nuclear antigen (EBNA)-1 and EBNA-2 in acute and chronic Epstein- Barr virus infection Proc Natl Acad Sci...

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Báo cáo khoa học: "Epstein-Barr virus latent membrane protein-1 (LMP-1) 30-bp deletion and Xho I-loss is associated with type III nasopharyngeal carcinoma in Malaysia" docx

Ngày tải lên : 09/08/2014, 07:21

... the Epstein Barr virus (EBV) BNLF-1 gene in both malignant and benign EBV associated diseases: High frequency of a 30 bp deletion in Malaysian and Danish peripheral T -cell lymphomas Blood 1994, ... 84:4053-4060 Dolcetti R, Zancai P, De Re V, Gloghini A, Bigoni B, Pivetta B, De Vita S, Carbone A, Boiocchi M: Epstein Barr virus strains with latent membrane protein-1 deletions: prevalence in the Italian ... 30-bp deletion of Epstein- Barr virus latent membrane protein-1 gene has no effect in nasopharyngeal carcinoma Laryngoscope 2006, 116(4):541-546 Tan EL, Peh SC, Sam CK: Analyses of Epstein- Barr virus...

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Báo cáo y học: "Possible roles of Epstein-Barr virus in Castleman disease" potx

Ngày tải lên : 10/08/2014, 10:20

... of Epstein- Barr virus Cancer Res 1981, 41:4253-61 Lerner MR, Andrews NC, Miller G, Steitz JA: Two small RNAs encoded by Epstein- Barr virus and complexed with protein are precipitated by antibodies ... are listed in Table Discussion Epstein- Barr virus is a lymphotropic herpesvirus and its infection rate varies geographically Usually, the clinical course after infection by EBV is indolent However, ... genotyping of Epstein- Barr virus by polymerase chain reaction using three gene loci (EBNA-2, EBNA-3C, and EBER): predominance of type A virus associated with Hodgkin's disease Blood 1993, 81:3372-81...

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Báo cáo y học: "Primary effusion lymphoma associated with Human Herpes Virus-8 and Epstein Barr virus in an HIV-infected woman from Kampala, Uganda: a case repor" pptx

Ngày tải lên : 11/08/2014, 00:22

... (cyclophosphamide, doxorubicin, vincristine, and prednisone); EBER: Epstein- Barr virus encoded RNA; EBV: Epstein- Barr virus; HAART: highly active antiretroviral therapy; HIV: human immunodeficiency virus; HHV-8: ... possible that PEL is being missed as an important subtype of AIDS-related NHL [13] Despite HIV, EpsteinBarr virus (EBV) and HHV-8 being endemic in Uganda, no case of PEL has, before now, been ... confirmed transmission by blood transfusion [9,10] In sub-Saharan Africa, there have been very few reports of PEL and this is probably because effusions are often not made into cell blocks, and even...

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Báo cáo y học: " Measurement of Epstein-Barr virus DNA load using a novel quantification standard containing two EBV DNA targets and SYBR Green I dye" pps

Ngày tải lên : 12/08/2014, 01:22

... 1.00 Abbreviations: EBV, Epstein- barr virus; EBNA-1, Epstein- barr virus nuclear antigen-1; BHRF-1, BamHI fragment H rightward open reading frame-1; VCA, viral capsid antigen; IgG, immunoglobulin ... 103 BHRF-1 Q Unknown HIV BHRF-1 EBNA-1, BHRF-1 P Unknown HIV EBNA-1 BHRF-1 O Unknown HIV Plasma (1/1) BHRF-1 N EBVAHS 1.1 × 105 BHRF-1 M/36y 7.5 × 104 BHRF-1 M EBNA-1 BHRF-1 EBNA-1, Whole Blood ... EBNA-1 is needed for efficient, stable latent infection by Epstein- Barr virus J Virol 1999, 73(4):2974-82 34 Henderson S, et al: Epstein- Barr virus- coded BHRF1 protein, a viral homologue of Bcl-2,...

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Báo cáo y học: " Genome-wide analysis of host-chromosome binding sites for Epstein-Barr Virus Nuclear Antigen 1 (EBNA1)" pot

Ngày tải lên : 12/08/2014, 01:22

... the EBNA1 DNA binding domain, which functions as a dominant negative in EBV infected cells, can inhibit cell viability in uninfected cells, suggesting that EBNA1 binds to and regulates cellular ... expression of EBNA1 activates a subset of genes with EBNA1 binding sites EBV negative Burkitt lymphoma cell line DG75 was transfected with Control vector (grey bars) or with FLAG-EBNA1 (black bars) expression ... Edwards AM: Crystal structure of the DNA-binding domain of the Epstein- Barr virus origin-binding protein, EBNA1, bound to DNA Cell 1996, 84:791-800 12 Bochkarev A, Barwell JA, Pfuetzner RA, Furey WJ,...

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