epstein barr virus and the infectious mononucleosis syndrome

... by the HLA-Dw4 DR β-1 chain and the Epstein- Barr virus glycoprotein gp110 Proc Natl Acad Sci USA 1989, 86:51045108 Lotz M, Roudier J: Epstein- Barr virus and rheumatoid arthritis: cellular and ... cytomegalovirus, Epstein- Barr virus and herpes virus- 6 in patients with rheumatoid arthritis with or without Sjogren’s syndrome Br J Rheumatol 1994, 33:317322 43 Meyer O: Parvovirus B19 and autoimmune ... onset p107, the major epitope of the EBV-encoded EBNA-1 antigen, recognize and bind to denatured collagen and keratin [81] These findings support the hypothesis that molecular mimicry, either by...

Ngày tải lên: 09/08/2014, 07:20

... of the unmodified TetR The original tetracycline repressor simply binds to a tandem of the type tetracycline operator (tetO2) operator and thus blocks transcription from the upstream cytomegalovirus ... tetracycline or doxycycline to the culture medium turns on expression: the inducer binds to the repressor, which then dissociates from the operator From the lack of interaction of the unmodified TetR with ... parent and fragment, respectively (collision energy: 24 V; scan time: 0.3 s) The area of the intensity versus time peak was integrated and divided by the area of the MPP+ peak to yield the analyte...

Ngày tải lên: 23/03/2014, 09:21

... fatal infectious mononucleosis; HLA = human leukocyte antigen; IM = infectious mononucleosis; NOS = not otherwise specified; TCR = T cell receptor; VAHS = virus- associated hemophagocytic syndrome ... data and wrote the manuscript; CA performed research and analyzed data; ES and FB analyzed data; SC and GM were responsible for patient care and provided clinical information; AG, CM, SR, and ... analyzed data; SAP and PPP performed research, analyzed data and wrote the manuscript All authors read and approved the final manuscript VT and CA contributed equally to this work; SAP and PPP contributed...

Ngày tải lên: 10/08/2014, 23:21

... Detection of Epstein- Barr virus by PCR and expression of LMP1, p53, CD44 in gastric cancer Korean J Intern Med 2004, 19:43-47 Andal N, Shanthi P, Krishnan KB, Taralaxmi V: The Epstein Barr virus and gastric ... EBVaGC, NPC biopsies and TWs of healthy donors in Northern China The numbers in the first row correspond to the amino acid positions and the numbers in the second correspond to the nucleotide positions, ... of genetic diversity of Epstein- Barr virus and its geographic and disease patterns: a need for reappraisal Virus Res 2009, 143:209-221 Hsu JL, Glaser SL: Epstein- barr virus- associated malignancies:...

Ngày tải lên: 12/08/2014, 02:20

... Anti-EBV antibody responses The function of the anti-EBV humoral immune response is to limit the infectious virus particles and therefore, to control the spread of the virus in the late stages of infection ... Figure Epstein- Barr virus (EBV) life cycle Epstein- Barr virus (EBV) is transmitted by contact with the infected saliva The current concept holds that EBV invades the nasopharyngeal mucosa and infects ... described by the first model and the high level of viremia in the germinal centers in infectious mononucleosis causes the infection of bystander germinal center cells, pushing them into the latency...

Ngày tải lên: 10/09/2015, 09:22

... CB, FKN, and DN conceived the study and designed the experiments MB, CB, JAS, JS, and AB participated in the experimental data collection MB analyzed the data MB, CB, and DN drafted the manuscript ... expresses the EBV nuclear antigen (EBNA) gene and is characteristic of BL The latency II program expresses EBNA1 plus the latent membrane proteins (LMP) and LMP2 and is seen in Hodgkin's disease and the ... transformed by Epstein- Barr virus Cancer Res 2004, 64(10):3361-3364 Ambinder RF, Robertson KD, Moore SM, Yang J: Epstein- Barr virus as a therapeutic target in Hodgkin's disease and nasopharyngeal...

Ngày tải lên: 20/06/2014, 01:20

... HFSand HSSplanned the experiment and performed most of the experiments with the help and supervision of HFS WKYselected the blocks, performed the paraffin tissues sectioning and prepared patient ... with Epstein- Barr virus in preinvasive lesions related to nasopharyngeal carcinoma The New England Journal of Medicine 1995, 333:693-698 Dawson CW, Rickinson AB, Young LS: Epstein- Barr virus ... resembles the China [31] and DV-Asp335 strain [32] The codon 335, which is located outside the known functional domains (CTAR1 and CTAR2) is involved in the nuclear factor (NF)-κβ signaling and has...

Ngày tải lên: 09/08/2014, 07:21

... Correlation between the Epstein- Barr virus viral load and Epstein- Barr virus- specific T-cell response Correlation between the number of IFNγproducing T cells and the Epstein- Barr virus (EBV) viral ... meta-analysis of randomized controlled trials of infliximab and adalimumab identified 10 cases of lymphoma (four cases in the randomized phase of the trials and six cases in the extension phase) in the treated ... for citation purposes) cross-sectional study Epstein- Barr virus load in peripheral blood mononuclear cells in the cross-sectional study Epstein- Barr virus (EBV) load distribution in control individuals...

Ngày tải lên: 09/08/2014, 14:21

... pattern, i.e., anti -Epstein- Barr virus- viral capsid antigen (VCA) IgM

Ngày tải lên: 10/08/2014, 22:20

... patient data and revised the manuscript LOO did cytotechnology and revised the manuscript PPP and SAP reviewed and revised the manuscript All authors read and approved the final version of the manuscript ... prednisone); EBER: Epstein- Barr virus encoded RNA; EBV: Epstein- Barr virus; HAART: highly active antiretroviral therapy; HIV: human immunodeficiency virus; HHV-8: human herpesvirus 8; KSHV: Kaposi ... Zambia and South Africa Nigeria, Ghana, Zimbabwe and Egypt have prevalence rates of 50% and the countries with relatively low rates of 25% and below are the Central African Republic, Eritrea and...

Ngày tải lên: 11/08/2014, 00:22

... quantitative PCR assays for the simultaneous detection of herpes simplex virus, varicella zoster virus, cytomegalovirus, Epstein- Barr virus, and human herpesvirus DNA in blood and other clinical specimens ... Bauer CC, et al: Serum Epstein- Barr virus DNA load in primary EpsteinBarr virus infection J Med Virol 2005, 75(1):54-8 45 Dehee A, et al: Quantification of Epstein- Barr virus load in peripheral ... assessing methods for the detection and quantification of EBV and other viruses [27,74,75] Conclusion This is the first reported study that uses the SYBR Green I dye on the Rotor-gene 6000™ with...

Ngày tải lên: 12/08/2014, 01:22

... exist in the nucleus, which allow for amplified expression of the therapeutic gene A standard vector derived from the Epstein Barr Virus contains the origin of replication oriP and the sequence ... met the oriP If that is the case, our stand that the arrest of the transcription complex along the DNA template prevents the DNA replication complex from recognizing and binding to the oriP, thereby ... replication of the vector and the Introduction expression of the therapeutic gene that is carried on the vector must occur Therefore, a better understanding of the relationship between replication and transcription...

Ngày tải lên: 05/10/2015, 21:24

... organized, the equipment and systems available to them, and the fiscal resources they command) represents the public health infrastructure for TB control The responsibility for TB control and prevention ... between the jurisdictional health department and the affected community The community should gain an understanding of the TB problem as it relates to them and should participate in the design of the ... disease and preserve the health of the entire population from which these patients are drawn As programs move from Tier to Tier and Tier populations, the complexity of the effort and the cost of the...

Ngày tải lên: 06/03/2014, 04:20

... beyond the endotracheal tube tip The inner catheter is then extended cm further and the protective plug expelled, allowing the brush to be advanced another 1-2 cm, and then retracted into the sheath ... techniques for respiratory viruses (such as rhinovirus, RSV, human metapneumovirus, parainfluenza viruses, influenza A and B viruses, adenovirus, coronavirus, and human bocavirus), and bacteria (including ... [221] Parainfluenza Virus, Adenovirus, Metapneumovirus, Rhinovirus, Coronavirus, and Bocavirus There no data from prospective, controlled studies for antiviral therapy against these viruses that are...

Ngày tải lên: 28/03/2014, 09:20

... to stand on ice for 3–5 and then repeatedly pipet it on to the monolayer until the cells have detached The cells are then removed to a microcentrifuge tube and the dish rinsed out with a further ... S., Barrell, B., and Farrell, P J (1990) Sequence and transcription of Raji Epstein- Barr virus DNA spanning the B95-8 deletion Virology 179, 339–346 Allan, G J and Rowe, D T (1989) Size and stability ... Mini-EBV Virus Plasmids 23 Genetic Analysis and Gene Expression with Mini -Epstein- Barr Virus Plasmids Ellen Kilger and Wolfgang Hammerschmidt Introduction Upon infection with Epstein- Barr virus...

Ngày tải lên: 10/04/2014, 22:31

... after NPC therapy and the EBV seroreactivity declined On the other hand, the unaffected individuals from high-risk families and community controls showed no statistical differences in the antibody ... patients during and after radiotherapy and/ or chemotherapy Figure Fluctuations of EBV antibody levels in four representative NPC patients during and after radiotherapy and/ or chemotherapy The Y axis ... and antibody profiles in epstein- barr virus genome-positive and negative hodgkin lymphoma J Infect Dis 2004, 189:2271-2281 Ambinder RF: Epstein- Barr virus associated lymphoproliferations in the...

Ngày tải lên: 18/06/2014, 15:20

... designed the research and supervised the study CFH was responsible for the patient samples and tissue array construction JHH and QS supported the work of IHC LXY supported the lab work XFZ and YXZ ... further clarify the signaling pathways regulated by LMP1 in NPC, we investigated the association between the mTOR signaling pathway and LMP1, the expression of p-mTOR, p-P70S6K and p-4EBP1, and ... (NC)-siRNA acted as an internal standard LMP1 expression was in the membrane and cytoplasm, with pmTOR and p-4EBP1 The location of LMP1 and p-mTOR or p-4EBP1 in the C666-1 cell line overlapped...

Ngày tải lên: 18/06/2014, 16:20

... as compared to Epstein- Barr virus serology Anticancer Res 1981, 1:187-94 Neel HB III, Pearson GR, Weiland LH, et al.: Application of Epstein- Barr virus serology to the diagnosis and staging of ... in the nucleus (Fig 3) The serology detected an EBV infection, with viral presence on the nasal and pharyngeal smears and on the blood polymorphonucleates Tests for HHV6 and VRS were negative The ... angiectatic-edematous aspects of the stroma and inflammatory infiltration of the lymphoplasma cells and eosinophilia" The ultrastructure study for the search for virus or viral particles conducted by the Electron...

Ngày tải lên: 19/06/2014, 08:20

... suppressing the silencing of their RNA The Rice yellow mottle virus, belonging to the Sobemovirus genus, is endemic to Africa and is the major pathogen of irrigated rice [15,16] Its genome and particle ... to evaluate both virus content and isolate effects with the Fisher test Taken together our results at the virion scale demonstrate that the accumulation and genetic diversity of the P1 suppressor ... of the diversity of P1 with a divergence up to 17.8% were selected These isolates are representative of the diversity of the other parts of the genome as phylogenetic reconstruction from the...

Ngày tải lên: 20/06/2014, 01:20

... or acceptance of hypotheses, rather than an assessment of degrees of likelihood The p value in null hypothesis testing represents the probability of the data if the null hypothesis is true We believe ... trying to impose narrow norms and methods on scientific practice and today emphasizes the diversity of methods and of the means of discovery and justification [4,5] The scientific method is what ... information on the probability of finding a specific or more extreme event when the null hypothesis is true; they say nothing at all about the probability of a null hypothesis being true Null-hypothesis-testing...

Ngày tải lên: 20/06/2014, 01:20