epithelial malignancies of the head and neck

... a nodular mass at the angle of the jaw The masses gradually increase in size and number and form sinuses that open onto the face and neck Although infection is often seen in the jaw area, Actinomyces ... several ways in the head and neck area Many of these lesions have been (or will be) discussed separately Almost 70% of HIV-infected patients will have lesions involving the head and neck. 130-136 ... EBV, and human herpesvirus (HHV)-6, HHV-7, and HHV-8 can have manifestations in the head and neck HSV-1 and HSV-2 Infection with HSVs may result in significant head and neck manifestations The...

Ngày tải lên: 19/02/2014, 08:20

... experts in the field of the pathology of the head and neck As such they are the main members of the Working Group on Pathology of the Head and Neck of the European Society of Pathology, one of the first ... the Head and Neck is that the proximity of the organs of the head and neck region makes it difficult for the surgical pathologist to focus on one of these organs and neglect the pathology of others, ... description of the manifold aspects of the morphology and pathology of the organs of the head and neck region These description, as comprehensive as they may be, also show that there are some areas of the...

Ngày tải lên: 29/06/2014, 09:20

... Adenocarcinoma of the Salivary Glands Report of Seven Cases and Review of the Literature Cancer 1996, 78:2471-2477 Ellis GL, Wiscovitch JG: Basal cell adenocarcinoma of the major salivary glands Oral ... parotidectomy +/- postoperative radiotherapy was planned CT revealed that the clinical stage was T3N1M0 (stage III) The diameter of the primary tumor was 54 mm and the diameter of the right upper cervical ... Radiotherapy Doses of carbon ions were expressed in photon equivalent doses (GyE), which were defined as the physical doses multiplied by the RBE of the carbon ions The biological flatness of the...

Ngày tải lên: 09/08/2014, 09:20

... malignancy of the head and neck Otolaryngol Head Neck Surg 2004, 131:643-645 Patel SG, See AC, Williamson PA, Archer DJ, Evans PH: Radiation induced sarcoma of the head and neck Head neck 1999, ... poor prognosis of these patients and also the beneficial effects of surgery for these tumors [21,25,29-33] In addition, the poor prognosis of radiation-induced sarcoma of the head and neck might ... the site and pathological diagnosis, the interval from the time of RT to the diagnosis of the second HNC, and the clinical course of the second cancer We calculated the expected numbers of second...

Ngày tải lên: 09/08/2014, 10:20

... cystic carcinomas of the head and neck are a unique kind of tumour deriving from cells of the major and minor salivary glands, they account for 25% of all malignant salivary gland tumours in different ... material wrapped around the head of the patient Serial mm CT slices of the of the whole treatment area plus a superior margin of cm and an adequate inferior margin to cover the neck lymph nodes level ... modulated radiation therapy and inverse treatment planning for tumors of the head and neck region: clinical implementation of the step and shoot approach and first clinical results Radiother Oncol 2003,...

Ngày tải lên: 09/08/2014, 10:21

... been evolved for the MMPs in potentially malignant and malignant lesions of the head and neck Further research is required for the development of their potential diagnostic and therapeutic possibilities ... control at the protein levels Regulation of MMPs in potentially malignant and malignant head and neck lesions Polymorphism of MMPs in potentially malignant and malignant head and neck lesions The MMPs ... to review the role, polymorphic association, gene expression of ECM and possible therapeutic aspects of MMPs and TIMPs in potentially malignant and malignant lesions of the head and neck Classification...

Ngày tải lên: 10/08/2014, 05:21

... in the head and neck area, hypopharynx and oropharynx, were available for the risk of predisposing CHK2 mutations In the present study, we did not find the CHK2 1100delC variant in any of these ... of the sequencing, isolated DNA, organized the study and wrote most parts of the article GP collected the patient’s samples and isolated DNA MW wrote parts of the article, collected samples and ... this group of patients, they did not detect any truncating mutation Therefore, we were able to confirm these results Nevertheless, they found the missense I157T mutation in 4.1% of the cases In...

Ngày tải lên: 11/08/2014, 07:21

... in terms of parotid gland sparing The IMRT technique should therefore represent the standard of care for the treatment of head and neck tumors Parotid-gland-sparing up to mean doses of 26 Gy ... significantly impact on the Dmean of the parotids, and thus on the saliva flow and recovery of parotid gland Keywords head and neck cancer; irradiation, saliva; hyposalivation; parotid gland sparing; recovery ... circumstances that the protection of at least one single parotid is achieved either with 3DCRT and IMRT Depending on the radiation dose to the salivary glands the time of recovery of the parotid glands should...

Ngày tải lên: 09/08/2014, 09:21

... spreads to the lymph nodes 11 of the neck, and this is often the first (and sometimes only) sign of the disease at the 12 time of diagnosis HNCs are highly associated with certain environmental and ... known as the resonance frequency which flip the spin 24 of the protons in the magnetic field, and after the electromagnetic field is turned off, 25 the spins of the protons return to thermodynamic ... parameter in the interpretation and rendering of diagnostic decision algorithms for in vivo tissue diagnosis and characterization in the head and neck Further, we also explored the utility of transnasal...

Ngày tải lên: 09/09/2015, 10:09

... computed for each of the raters using the respective other raters as reference, that is, the mean of the four other raters for the LE group and the three other raters for the OC group For the comparison ... is the number of correctly recognized words, and R is the number of words in the reference Table 1: Effect of the n-gram language model on the oral cancer (OC) data: with growing context of the ... As a precondition for the evaluation of the patient groups, the extent of disorder is widespread, as seen by the results of the perceptual assessment and the ASR results The presented method might...

Ngày tải lên: 21/06/2014, 20:20

... the wells and color developed in proportion to the amount of the cytokine bound in the initial step By comparing the optical density of the samples to a standard curve, the concentration of the ... participated in the design of the study and clinical evaluations MK participated in the design of the study and clinical evaluations, and carried out the writing of the manuscript SB, RAB, AS, TP and MS ... answer to the question of the relationship between levels of IL-6 and IL-8 and severity of mucositis during and after radiotherapy In addition, it should be emphasized that because of the small...

Ngày tải lên: 09/08/2014, 08:22

... types of head and neck cancer in the maxillofacial area Carcinomas and sarcomas of the maxillofacial region were commonest in the maxilla, while the highest number of lymphomas occurred in the mandible ... [44] Conclusion The clinico-pathological summary of head and neck malignancies in western Nigeria is not different from profiles in other parts of the world Malignancies of epithelial lineage ... other lineages in the head and neck whereas neuroendocrine tumours of the head and neck are rare It is expedient to conduct this sort of study periodically to monitor the changing trends of head...

Ngày tải lên: 11/08/2014, 20:21

... of the bony part and the skin pedicle Seven of these patients (patient 1–7, Table 2) had immediate revision microsurgery Findings consisted of arterial thrombosis and thrombosis of the vein The ... fibula grafts were used for mandibular reconstruction after resection of the symphysis in 23 patients, the mandibular body in 53 patients, the ramus in 37 patients and the condylar process in 14 ... uptake of the reconstructed mandible on the third postoperative day after microvascular revision surgery Vascularisation of the periosteal layer and intramedullary vessels can now be seen Page of...

Ngày tải lên: 11/08/2014, 23:22

... Ricker JL, Chen Z, Van Waes C: Role of activated nuclear factor-kappaB in the pathogenesis and therapy of squamous cell carcinoma of the head and neck Head Neck 2007, 29(10):959-971 Lee TL, Yang ... p53 status, which is consistent with either the loss of the negative regulation (PTEN and PPAR), or the suppression of NF-κB and other signal pathways and genes by gaining or retaining p53 functions ... alterations and the biological and clinical significance of NF-κB activation and of multiple NF-κB-regulated genes and cytokines expressed in HNSCC tumor specimens and serum [18,32,33,42,80,81], and the...

Ngày tải lên: 14/08/2014, 08:20

... regeneration, epithelial precursors arrived from the borders of epithelial damage to proliferate and differentiate there Mesenchymal cells situated below the epithelium regulate epithelial growth and differentiation ... about the mechanisms of wound healing and MMP expression of cells of the upper ADT in vitro and in vivo [120, 121] A comprehensive characterization of the MMP- and TIMP expressions of cells of the ... between the AB-copolymer network and the control group [136] The analyses of the mechanisms of the integration of the implant material in the adjacent tissues as well as the mechanisms of material...

Ngày tải lên: 25/10/2013, 08:20

... of the carotid sheath 13 diagnosis and management of head and neck cancer 5.2.2 surgical treatment Neck dissection removes both the soft tissue and the lymph nodes A number of modifications of ... wall and the inferior surface of the soft palate and uvula The choice of therapeutic option for patients with cancer of the oropharynx should be determined by the tumour’s site and extent, the ... at the site of the primary tumour is the most common cause of treatment failure and disease-related death in patients with head and neck cancer Therapeutic options for patients with head and neck...

Ngày tải lên: 14/02/2014, 22:20

... ACKNOWLEDGMENTS The American Head and Neck Society Committee acknowledges the input from the Head and Neck Surgery and Oncology Committee and the Head and Neck Surgery Education Committee of the American ... Guide to NECK DISSECTION CLASSIFICATION AND TNM STAGING OF HEAD AND NECK CANCER Committee for Head and Neck Surgery and Oncology American Academy of Otolaryngology– Head and Neck Surgery Neck Dissection ... Academy of Otolaryngology Head and Neck Surgery, and the Council of the American Head and Neck Society Appreciation is also extended to Douglas Denys, MD, for the illustrations and the AJCC for the...

Ngày tải lên: 15/03/2014, 00:20

... mucosal surface of the lip DIAGRAM OF THE HEAD AND NECK Oral cavity Oropharynx Larynx Hypopharynx ALL HEAD AND NECK CANCERS DIAGRAM OF THE LYMPH NODES LEVELS IN THE NECK I II III VI IV V NECK DISSECTION ... provides a summary of the main recommendations in the SIGN guideline on the Diagnosis and management of head and neck cancer Recommendations are graded A B C D to indicate the strength of the supporting ... of the ipsilateral neck only is required Bilateral treatment of the neck is recommended when the incidence of occult disease in the contralateral neck is high (tumour is encroaching on base of...

Ngày tải lên: 15/03/2014, 01:20

... from the date of start of chemotherapy to the date of death or most recent follow-up Progression free The median age of the patients was 53 years (range 3672 years), and fifty-five (96.5%) out of ... cisplatin is the backbone of the chemotherapy regimen as a component of IC and CCRT in the treatment of locally advanced HNSCC Its main cytotoxic activity is based on the formation of DNA adducts, ... (creatinine clearance >60 ml/min), and a computed tomography or magnetic resonance image scan of the head and neck region within three weeks prior to the initiation of treatment The clinicopathological...

Ngày tải lên: 18/06/2014, 19:20