epigenetics and assisted reproduction

... maintenance Figure ART and possible imprinting defects ART and possible imprinting defects Possible interactions between different steps of assisted reproduction procedures and imprint establishment ... expressed genes IGF2 and KCNQ1OT1, and the maternally expressed genes H19, CDKN1C and KCNQ1 [14] Approximately 25 to 50% of BWS patients have biallelic expression of the IGF2 gene, and some of these ... writing of this review and both read and approved the final manuscript Imprinting and placenta A critical way of regulating intrauterine development is through placental function and growth Most imprinted...

Ngày tải lên: 14/03/2014, 16:20

... Genomics – Integrating Genomics and Epigenetics into National and European Health Strategies and Policies 267 Tobias Schulte in den Bäumen and Angela Brand Public Health and Genomics 267 The Bellagio ... Network 40 “Mendelian Randomization” 41 Methylenetetrahydrofolate Reductase Gene Polymorphisms (C677T and A1298C) and Its Association with Cancer Risk 41 Gene and Function 41 C677T and A1298C Gene Variants ... Genomics and Nutrition Research 129 Transcriptomics and Nutrition Research 130 Proteomics and Nutrition Research 131 Metabolomics and Nutrition Research 132 Nutrigenetics 133 Nutri-Epigenetics...

Ngày tải lên: 15/03/2014, 04:20

... to utilise the full biological potential of gametes and embryos. Against this background, ESHRE finds it important  that there is coherence between a country’s decision to support assisted reproduction and the financial and regulatory strategies affecting the quality of the service provided.  ... safety. The role of ESHRE is also to support improvements in the field of medical practice and to promote the  safety and quality of clinical, surgical and laboratory procedures.    ESHRE considers it a fundamental principle that professionals in reproductive medicine and biology are allowed  ... informed about the possible negative effects of alcohol, smoking and body weight (overweight and underweight) on fertility, and preconceptional care should focus on assessing the risks of treatment and pregnancy in each individual case. Couples who have not conceived after one year of regular unprotected sexual ...

Ngày tải lên: 22/03/2014, 12:20

... Ghanem and Laila A Al-Boghdady Preface Since its first description by Steptoe and Edward, IVF gained popularity among both doctors and patients There is many studies on assisted reproduction and ... permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited 2 Enhancing Success of Assisted Reproduction - removing ovarian cysts unexplained ... uterine cavity and tubal anatomy are: transvaginal sonography (TVS), hysterosalpingography (HSG), hysteroscopy and hydrosonography (HDS) and laparoscopy In the evaluation of uterine and tubo-peritoneal...

Ngày tải lên: 23/03/2014, 14:20

... Introduction I Anthony Hughes and Erich Ranfft vu I Roman Sculptural Reproductions or Polykleitos: The Sequel Miranda Marvin Authority, Authenticity and Aura: WaIter Benjamin and the Case of Michelangelo ... Neue Frau (1995) and The Dictionary of Women Artists (London and Chicago, 1997) He has been researching modern German arts and cultures and the practices of women sculptors, and has a forthcoming ... categories: historical and 'ideal' Historical sculpture depicts historical persons and events? Public and private portraiture and the narrative reliefs that ornamented arches, columns and buildings throughout...

Ngày tải lên: 24/03/2014, 04:20

... double stranded strand break (DSB) DNA repair processes such as homologous recombination and single-strand annealing occur and the chromatin adjacent to this DSB plays a role in the repair and signalling ... silencing transcription factor)) and N-CoR and SMRT complexes are shown NuRD and sin3 complexes share the retinoblastoma associated protein (RbAp)46 and 48 proteins and also contain distinct sets ... active and/ or inducible genes and are referred to as CpG islands CpG islands generally consist of regions of >500 base pairs with a GC content greater than 55% [9,12] When methylated these CpG islands...

Ngày tải lên: 12/08/2014, 16:20

... Grinnan and Truwit Figure Compliance in emphysema and fibrosis Shown are changes in the compliance of the inspiratory limb of the pressure–volume curve with respect to (a) chest wall, (b) lungs, and ... care unit and is characterized by low compliance Typically, the start of inspiration occurs at low volumes (near the residual volume) and requires high pressure to overcome surface tension and inflate ... first section occurs at a low volume, and is nonlinear and relatively flat (low compliance) As the volume increases, the second section of the curve is linear and has a steeper slope (higher compliance)...

Ngày tải lên: 12/08/2014, 22:21

... one-generation selection for early and late reproduction in populations maintained for 10 generations at low and high levels of larval density work on MATERIALS AND METHODS Life history of Acanthoscelides ... melanogaster females and males Heredity 60, 55-60 Tuci6 N, Cvetkovi6 D, Stojiljkovi6 V, Bejakovi6 D (1990) The effects of selection for early and late reproduction on fecundity and longevity in bean ... proposed, the fundamental is &dquo;how long and short life spans evolve?&dquo; (Luckinbill and Clare, 1985) Having in mind the suggestion provided by MacArthur and Wilson (1967) that density dependent...

Ngày tải lên: 14/08/2014, 20:20

... volume, sperm concentration and number, sperm velocity and motility, sperm swimming characteristics, and sperm morphology, shape and size (Burger et al., 1989) Between fathers and fetuses Scientists ... (Kharrazi, Patashnik, and Goldsmith, 1980) Seventeen studies have now evaluated the impact of pesticides and herbicides on male reproduction and paternal–fetal health (Olshan and Faustman, 1993: ... palate and hydrocephalus (Savitz, Schwingle and Keels, 1991) SigniWcant associations have also been found between paternal smoking and brain cancer in children, and between paternal smoking and...

Ngày tải lên: 01/11/2013, 08:20

... FEBS 1599 MicroRNAs and epigenetics F Sato et al Fig Epigenetics miRNA regulatory circuit Epigenetics and miRNAs regulate whole gene expression pattern transcriptionally and posttranscriptionally, ... (Mathworks, Natick, MA, USA), we compared localization and strand direction between miRNAs and transcripts (Refseq genes and mRNAs) Intragenic and intergenic miRNAs were defined by whether the miRNAs ... in an ATP-dependent manner [20] Next, one strand (the passenger strand) of the miRNA is removed from the RLC, whereas the other strand (the guide strand) remains in the complex to form a mature...

Ngày tải lên: 14/02/2014, 19:20

... narrow-range IPG strip and suggested S100A8 and S100A9 as candidates for serological biomarkers in combination with other serum markers that aid CRC diagnosis Using our strategy combining gel -assisted digestion, ... maintains appropriate HLA class I redox status and enhances TAP and HLA class I levels [38,39] In summary, the strategy combining gel -assisted digestion and iTRAQ labeling LC-MS ⁄ MS has proven to ... and approval by Human Clinical Trial Committee at Chang Gung Memorial Hospital A total of eight tissue pairs containing tumoral and adjacent normal tissue were collected and analyzed by gel-assisted...

Ngày tải lên: 16/02/2014, 15:20

... of Val82 and Tyr85 in the turn (Val82-Asn83Gly84-Tyr85) between the S3 and S4 strands and the hydrophobic side chains of Pro34 and Leu38 N1 and N6 of the base of A20 lie close to Nd2 and Od1 of ... H18 and the X-loop of P horikoshii ArgRS and T thermophilus ArgRS Asn498, Phe499 and Glu500 in P horikoshii ArgRS and Ser464, Phe465 and Glu466 in T thermophilus ArgRS are shown in ball -and- stick ... Arg and the main chain C@O of Ser127 and ˚ O of the side chain of Asn129 are set at 3.15 A and ˚ , and the distances between the guanidinium 3.04 A moiety and the side chain of Glu124 (S5) and...

Ngày tải lên: 18/02/2014, 11:20

... stroked and made love to Their recognition of the importance of reproduction and women's domestic labor for capital accumulation led to a rethinking of Marx's categories, and a new understanding ... individual, its reproduction must simultaneously be a process of creation and valorization of desired attributes and capacities and an accommodation to the externally imposed standards of the ... shaped the sexual division of labor and the relations between women and men Here as well the substantive difference between production and reproduction stands out The first difference to be noticed...

Ngày tải lên: 05/03/2014, 17:20

... Smoking, fertility and very preterm birth Journal of Gynecology and Obstetric Biology of Reproduction 2003, 32:1S9-16 Daling JR: Cigarette smoking and primary tubal infertility In Smoking and Reproductive ... conception and active and passive smoking The Avon Longitudinal Study of Pregnancy and Childhood Study Team Fertil Steril 2000, 74:725-733 Kukla L, Hruba D, Tyrlik M: Smoking and damages of reproduction: ... steroids and prostaglandins Endogenous estrogens stimulate oviductal muscle contraction, while progesterone relaxes it [103] Likewise the prostaglandins PGF and PGE contract and relax oviductal...

Ngày tải lên: 05/03/2014, 17:20

... muscle and glands and the consumption of the cell substances of these tissues results in the development of the nerve, muscle [34 ]and gland cells into a condition larger, better equipped and more ... stallion are, first, the great breadth and depth of chest, great mass of shoulder and hip muscles, and the high arched neck, fiery eye and luxuriant mane and tail Second, the functional features ... in the limbs and back, nausea, sleeplessness and nervous irritability and fever, followed by the appearance of a rash upon the face and body, falling out of the hair, sore throat and mouth These...

Ngày tải lên: 06/03/2014, 13:20

... children and other loved ones about what the future may hold in terms of long term care needs By talking now and taking charge, you and your loved ones can be prepared for life’s twists and turns ... her, and once you’ve listened and addressed her concerns, she may be more willing to listen to you Open your heart and your mind Most likely, you will learn something new Ask questions and intent ... of supervision and care than what is provided in an assisted living facility They offer residents personal care assistance, room and board, supervision, medication, therapies and rehabilitation,...

Ngày tải lên: 06/03/2014, 19:20

... predict and optimize possible outcomes beforehand, which saves time in finding successful experimental strategies asap and searchxlinks [11] have the order of events hard coded into the program and ... Netherlands Organization for Scientific Research (NWO), Chemical Sciences division (CW) and Regieorgaan Genomics The ApexQ FTICR-mass spectrometer was largely funded by NWO-CW and the TofSpec 2EC and ... proteomic experiments and integrate these with mass spectrometric analyses The virtual experimental results allow rapid and convenient exploration of proteomics strategies and are used to generate...

Ngày tải lên: 07/03/2014, 12:20

... care, and child care; and safe home, work, and community environments With regard to reproduction, women need to be in charge of their own fertility and have access to a wide range of safe and ... of gametes and embryos, and germline engineering The AHRA also established the Assisted Human Reproduction Agency of Canada (AHRAC) to develop and oversee regulations covering these and other ... set regulatory and licensing standards for PGD in accordance with the principles of the AHRA PGD is illegal in Germany, Austria, and Switzerland In France, India and the Netherlands, regulation...

Ngày tải lên: 14/03/2014, 16:20

... °C and (b) 700 °C The scale bar is lm (c) TEM image of a SiNW with an Au particle tip and (d) corresponding silicon elemental mapping The scale bar is 50 nm (e) EDX spectrum of the nanowire and ... the SiNWs and limited the wire diameter The present SiO–Au approach offers certain advantages over the common metal-catalytic VLS method and the OAG method, such as the absence of toxic and flammable ... between 20 and 40 nm Consequently, the diameter of the nanowires is well limited by that of the Au caps HRTEM image (Fig 4a) shows the as-grown SiNWs consist of a crystalline core and an amorphous...

Ngày tải lên: 16/03/2014, 15:06