epidermal growth factor receptor antagonists or inhibitors act synergistically to kill tumor cells

Báo cáo y học: " Rac and Rho driving tumor invasion: who’s at the wheel" docx

Báo cáo y học: " Rac and Rho driving tumor invasion: who’s at the wheel" docx

Ngày tải lên : 14/08/2014, 21:20
... ROCK inhibitors such as Y27632 can be used to inhibit amoeboid motility while maintaining or increasing the proportion of cells that are invading in the mesenchymal mode Conversely, inhibitors ... critical mediator of the elongated phenotype Interestingly, depletion of either Rac1 or WAVE2 stimulated actomyosin contractility, evidenced by increased phosphorylation of the regulatory subunit ... reduced the fraction of elongated (mesenchymal) cells Moreover, siRNA-mediated depletion of Rac1 itself also reduced the fraction of elongated cells, while conversely, inhibitors of ROCK or myosin...
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Tài liệu 80C51 family programmer’s guide and instruction set pptx

Tài liệu 80C51 family programmer’s guide and instruction set pptx

Ngày tải lên : 20/01/2014, 03:20
... Accumulator 12 ORL A,@Ri OR indirect RAM to Accumulator 12 ORL A,#data OR immediate data to Accumulator 12 ORL direct,A OR Accumulator to direct byte 12 ORL direct,#data OR immediate data to direct ... Accumulator 12 ANL direct,A AND Accumulator to direct byte 12 ANL direct,#data AND immediate data to direct byte 24 ORL A,Rn OR register to Accumulator 12 ORL A,direct OR direct byte to Accumulator ... Exclusive -OR register to Accumulator 12 XRL A,direct Exclusive -OR direct byte to Accumulator 12 XRL A,@Ri Exclusive -OR indirect RAM to Accumulator 12 XRL A,#data Exclusive -OR immediate data to Accumulator...
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Tài liệu USAID/Haiti Maternal and Child Health and Family Planning Portfolio Review and Assessment pdf

Tài liệu USAID/Haiti Maternal and Child Health and Family Planning Portfolio Review and Assessment pdf

Ngày tải lên : 12/02/2014, 12:20
... to walk for many hours in order to supervise community-based health workers or provide basic care Poor transportation also undermines access to drugs and supplies and is one factor in the poor ... program data; other donor inputs; factors related to need and demand for, and quality of and access to, MCH/FP services; logistics of MCH/FP commodities, indicators and monitoring and evaluation ... person performing an abortion is subject to imprisonment, whether the woman consented to the abortion or not A pregnant woman who performs her own abortion or permits an abortion to be performed on...
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Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx

Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx

Ngày tải lên : 14/02/2014, 18:20
... for the potent viral inhibition Moreover, novel proteasome inhibitors that are less toxic and more specific are currently in the pipeline for clinical approval [64], and several ITK-specific inhibitors ... cells from transgenic mice, the ITK– SYK fusion was found to translocate to lipid rafts and was able to constitutively phosphorylate T-cell receptor- associated signaling proteins It is noteworthy ... decisive factor for this variation The B-cell adapter protein BLNK (SLP-65) and its T-cell counterpart SLP-76 are key signaling components downstream of immunoreceptors ITK–SYK has been reported to potently...
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Family Life, Reproductive Health, and Population Education: Key Elements of a Health-Promoting School docx

Family Life, Reproductive Health, and Population Education: Key Elements of a Health-Promoting School docx

Ngày tải lên : 22/03/2014, 12:20
... have stopped • are forced to engage in sexual relations (e.g., have been raped or forced by adults or peers to engage in sex in exchange for money or other favours) School personnel need to provide ... and population education Intentionally or unintentionally and for better or for worse schools play a significant role in contributing to or hindering efforts to address family life, reproductive ... objectives or steps make clear what needs to be done and when The clearer and more specific the objectives, the easier it will be to select appropriate activities to achieve them and to monitor and...
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Báo cáo khoa học: Tec family kinases: Itk signaling and the development of NKT ab and cd T cells potx

Báo cáo khoa học: Tec family kinases: Itk signaling and the development of NKT ab and cd T cells potx

Ngày tải lên : 28/03/2014, 22:21
... numbers in T cell receptor transgenic mice [6] More recently, Itk-deficient mice were reported to have reduced development of naı¨ ve or conventional CD4+ and CD8+ T cells, and normal or increased ... Like NK cells, they have the ability to rapidly produce large amounts of cytokines upon stimulation by ligands that interact with either their NK receptors or their TCRs These cells share portions ... of major histocompatability complex molecules on bone-marrowderived cells These nonconventional or innate memory phenotype T cells share characteristics with invariant natural killer T cells...
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Báo cáo khoa học: The carbohydrate-binding module family 20 – diversity, structure, and function doc

Báo cáo khoa học: The carbohydrate-binding module family 20 – diversity, structure, and function doc

Ngày tải lên : 30/03/2014, 01:20
... W495F GA SBD fused to b-galactosidasea GA SBD fused to b-galactosidasea CGTase SBD fused to b-galactosidasec CGTase SBD fused to b-galactosidasec CGTase SBDd CGTase double SBDd CGTased W616A ... D514 D455 CGTase GA SBD fused to b-galactosidasea a-Amylase-SBDe a Corn starch Corn starch Potato starch Corn starch Kd /relative adsorption Bmax References )1 Corn starch 19.6 lM 3.2 lM 3.3 ... phosphatase regulatory subunit Protein phosphatase regulatory subunit Protein phosphatase regulatory subunit AMPK b1 subunit AKIN-b-c-1 protein Starch excess protein SNF1-related regulatory subunit...
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family therapy concepts, process and practice

family therapy concepts, process and practice

Ngày tải lên : 29/05/2014, 16:15
... an authoritative parenting style and the involvement of both mothers and fathers in parenting are the Table 1.3 Factors associated with resilience in adolescence Domain Factors Family factors Absence ... belief systems that underpin exceptions to the problem Still others aim to modify the negative impact of historical, contextual and constitutional factors or to draw on family strengths in these ... Professor Peter Stratton, Editor of Human Systems: The Journal of Systemic Consultation and Management; to Max Cornwall, Editor of The Australian Journal of Family Therapy; to Professor Doug...
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The Impact of ParentalInvolvement  Parental Supportand Family Education on PupilAchievements and Adjustment A Literature Review

The Impact of ParentalInvolvement Parental Supportand Family Education on PupilAchievements and Adjustment A Literature Review

Ngày tải lên : 02/06/2014, 09:37
... once or twice, = three or more times) Discuss Activities … school activities or events of particular interest to you (0 = not at all, = once or twice, = three or more times) Monitor Homework How ... 1996) 2.12.4 Responses to these items were scored and the scores analysed to look for major patterns Four main factors were found to describe most parental involvement activity There were two ... described 24 as ‘vulnerable’ It was possible to identify the factors which seemed to promote resilience or protect from vulnerability Protective factors for the NCDS sample were having an educated...
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Báo cáo hóa học: "The Pediatric Quality of Life Inventory™ (PedsQL™) family impact module: reliability and validity of the Brazilian version" pdf

Báo cáo hóa học: "The Pediatric Quality of Life Inventory™ (PedsQL™) family impact module: reliability and validity of the Brazilian version" pdf

Ngày tải lên : 18/06/2014, 22:20
... translator whose native language was English This translator had no access to the original instrument A subsequent comparison between the original version and the backtranslated version was performed ... Item 2: difficult to speak about my child's illness Item 3: difficult to tell the doctors and nurses how I feel Worry Item 1: worry whether my child's treatment is working Item 2: worry about the ... Item 1: family activities takes more time and effort Item 2: difficult to find time to finish the household chores Item 3: fatigue made it difficult to finish the household chores Family Relationships...
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báo cáo hóa học:" Research Article Strong Convergence of a New Iterative Method for Infinite Family of Generalized Equilibrium and Fixed-Point Problems of Nonexpansive Mappings in Hilbert Spaces" pptx

báo cáo hóa học:" Research Article Strong Convergence of a New Iterative Method for Infinite Family of Generalized Equilibrium and Fixed-Point Problems of Nonexpansive Mappings in Hilbert Spaces" pptx

Ngày tải lên : 21/06/2014, 11:20
... that an operator A : H → H is called to be strongly positive with coefficient γ > if Ax, x ≥ γ x , ∀x ∈ H 1.3 Let u ∈ H be a fixed point, A be a strongly positive linear bounded operator on H and ... satisfies the following: for all x ∈ C; A1 G x, x A2 G is monotone, that is, G x, y G y, x ≤ for all x, y ∈ C; A3 For each x, y, z ∈ C, − t x, y ≤ G x, y ; lim G tz t↓0 2.12 A4 For each x ∈ C, y → G ... Functional Analysis, Fixed Point Theory and Its Application, Yokohama Publishers, Yokohama, Japan, 2000 22 H.-K Xu, “Iterative algorithms for nonlinear operators,” Journal of the London Mathematical...
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Báo cáo hóa học: "Research Article Some Characterizations for a Family of Nonexpansive Mappings and Convergence of a Generated Sequence to Their Common Fixed Poin" pdf

Báo cáo hóa học: "Research Article Some Characterizations for a Family of Nonexpansive Mappings and Convergence of a Generated Sequence to Their Common Fixed Poin" pdf

Ngày tải lên : 21/06/2014, 20:20
... that g 0 We have the following theorem 11, Theorem for a uniformly convex Banach space Theorem 2.1 Xu 11 E is a uniformly convex Banach space if and only if, for every bounded subset B of E, there ... accretive λ y1 − y2 for every λ > and x1 , x2 , y1 , y2 ∈ E with operator if x1 − x2 ≤ x1 − x2 y1 ∈ Ax1 and y2 ∈ Ax2 Let A be an accretive operator and r > We know that the operator I rA has a single-valued ... more details, see, for example, 15 We have the following result for the resolvents of an accretive operator by 25 ; see also 15, Theorem 4.6.3 , and 16, Theorem 3.4.3 Theorem 4.5 Let C be a...
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Báo cáo toán học: "On a new family of generalized Stirling and Bell numbers" pps

Báo cáo toán học: "On a new family of generalized Stirling and Bell numbers" pps

Ngày tải lên : 08/08/2014, 14:23
... operator, and the normal ordering is related to Touchard polynomials [7] Varvak considered variables U, V satisfying (5) for s ∈ N0 and their normal ordering and she pointed out the connection to ... are record lows in the second, and is a record low in the third block for a total of six record lows altogether (For convenience, we will arrange the blocks in ascending order according to the ... [32] M Schork, On the combinatorics of normal ordering bosonic operators and deformations of it, J Phys A: Math Gen 36 (2003) 4651–4665 [33] M Shattuck and C Wagner, Parity theorems for statistics...
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family therapy concepts process and practice phần 1 ppsx

family therapy concepts process and practice phần 1 ppsx

Ngày tải lên : 14/08/2014, 05:20
... an authoritative parenting style and the involvement of both mothers and fathers in parenting are the Table 1.3 Factors associated with resilience in adolescence Domain Factors Family factors Absence ... belief systems that underpin exceptions to the problem Still others aim to modify the negative impact of historical, contextual and constitutional factors or to draw on family strengths in these ... Professor Peter Stratton, Editor of Human Systems: The Journal of Systemic Consultation and Management; to Max Cornwall, Editor of The Australian Journal of Family Therapy; to Professor Doug...
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family therapy concepts process and practice phần 2 potx

family therapy concepts process and practice phần 2 potx

Ngày tải lên : 14/08/2014, 05:20
... those more liberating and flexible belief systems that underpin exceptions to the problem Still others aim to modify the negative impact of historical, contextual and constitutional factors or to ... theory, and family factors in the development of schizophrenia have been particularly important Work Group Dynamics Kurt Lewin (1951), a Gestalt psychologist interested in the performance of work ... commonly denied, distorted or relabelled the patients’ experiences so as to compel the patient to conform to the parents’ expectations Laing used Karl Marx’s term ‘mystification’ to refer to this process...
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family therapy concepts process and practice phần 3 potx

family therapy concepts process and practice phần 3 potx

Ngày tải lên : 14/08/2014, 05:20
... predominantly with historical predisposing factors Multisystemic therapy pays particular attention to the role of contextual predisposing factors Managing constitutional predisposing factors is a central ... Solutions in Brief Therapy New York: Norton deShazer, S (1991) Putting Difference to Work New York: Norton deShazer, S (1994) Words were Originally Magic New York: Norton deShazer, S., Berg, I., ... happen in future Identify factors that prevent deterioration Clients are invited to identify factors that prevent complex or volatile problematic situations from deteriorating further Miracle question...
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family therapy concepts process and practice phần 4 potx

family therapy concepts process and practice phần 4 potx

Ngày tải lên : 14/08/2014, 05:20
... the fact that people may be predisposed to developing such behavioural patterns and belief systems because of factors in their history; factors in the wider social network outside the family; or ... modifying the impact of historical predisposing factors Multisystemic therapy, which will be described in the next section, in contrast, aims to modify the role of predisposing contextual factors in the ... analyse network roles accurately before deciding who to invite to the first session Most network members fall into one or more of the following categories: • The referrer, to whom correspondence...
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family therapy concepts process and practice phần 5 pps

family therapy concepts process and practice phần 5 pps

Ngày tải lên : 14/08/2014, 05:20
... include: historical factors within the parents’ families of origin; contextual factors in the wider social system, such as poverty; and constitutional factors, such as vulnerability to illness or disability ... Contextual Factors Problem-maintaining behaviour patterns and the belief systems and narratives that subserve these may arise from predisposing factors These predisposing factors may be rooted in historical ... constitutional predisposing factors or mobilise protective factors or family strengths within these domains The three-column framework given in Table 9.1 organises some of the more important therapeutic...
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family therapy concepts process and practice phần 6 docx

family therapy concepts process and practice phần 6 docx

Ngày tải lên : 14/08/2014, 05:20
... three-column formulation of physical child abuse parent Historical factors, such as personal abuse in childhood; contextual factors, such as high stress and low marital support; and constitutional factors, ... responsible for the abuse Predisposing Historical Contextual and Constitutional Factors A range of historical, contextual and constitutional factors associated with the perpetrator, the child ... context may predispose families to the occurrence of child sexual abuse SEXUAL ABUSE 345 Perpetrator Factors A range of factors underpin perpetrators’ motivation to abuse including being aroused...
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