epidemiology of type 2 diabetes mellitus in pediatric populations

... Chin PLA 1996, 21 (9) :27 0 -27 2 26 Tang L, Chen X, Chen H, Zhao L, Hu S: The financing burden of treatment of diabetesII and Its symptom in urban China Chinese Health Economics 20 03, 22 ( 12) :21 -23 ... 434 161 (37.1) 39 (9.0) 122 (28 .1) 53 ( 12. 2) 95 (21 .9) (1.4) 28 9 (66.6) χ2trend = 32. 30 χ2trend = 11.09 χ2trend = 65.49 χ2trend = 3.95 χ2trend = 25 . 62 χ2trend = 4.54 χ2trend = 91.90 p < 0.001 ... the year 20 00 Diabetes Care 20 05, 28 (9) :21 30 -21 35 Shaw JE, Sicree RA, Zimmet PZ: Global estimates of the prevalence of diabetes for 20 10 and 20 30 Diabetes Res Clin Pract 20 10, 87(1):4-14 King H,...

Ngày tải lên: 12/08/2014, 01:21

... al Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type diabetes Diabetes 20 02; 51 :20 74 -20 81 13 DeFronzo R, Goodman A Efficacy of metformin in patients ... glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type diabetes Diabetes Care 20 03 ;26 :23 70 -23 77 27 Lindsay JR, Duffy ... factor C3 in overweight patients with type diabetes mellitus Diabetes Med 20 05 ;22 : 128 2- 128 4 34 Jung HS, Youn BS, Cho YM, Yu KY, Park HJ, Shin CS, et al The effects of rosiglitazone and metformin on...

Ngày tải lên: 12/07/2015, 15:49

... inhibitors Insulin 14 .2 (10.4-18) 14.4 (10.4-18.4) 0.94 Diuretics 27 .4 (22 .5- 32. 3) 23 .1 (18.3 -27 .9) 0 .23 Beta blockers 12. 9 (9 .2- 16.6) 9.7 (6.4-13.1) 0 .22 ACE inhibitors 30.6 (25 .5-35.7) 29 .1 (24 -34 .2) ... Control PRECEDE 28 .7 24 .8 29 .3 28 0.91 0 .29 +0.6 +3 .2 0. 02 DBP (

Ngày tải lên: 05/03/2014, 22:21

... improvement in fitness by mL/kg·min of VO2peak was associated with a 4-point increase in general health in the final model [Additional file 1] Type diabetes was associated with an 8-point decrease in ... hemoglobin A1c; HRQOL: health-related quality of life; kg: kilogram; m: meter; mL: millileter; min: minute; SD: standard deviation; Type diabetes: type diabetes mellitus; T2DM: type diabetes mellitus; ... people with type diabetes are now including both a diabetes- specific and a general measure of HRQOL [ 12, 26] Finally, the sample size of 21 7 may have reduced our power to detect differences in HRQOL,...

Ngày tải lên: 18/06/2014, 19:20

... patients with type diabetes Adv Ther 20 05, 22 : 621 -635 28 Taki H, Maki T, Iso T, Iwamoto K, Kajiura T: Postmarketing surveillance study of nateglinide in Japan Adv Ther 20 05, 22 :513- 526 29 Biswas ... safety profile and glycemic control of pioglitazone in more than 20 ,000 patients with type diabetes mellitus: postmarketing surveillance study in Japan Diabetes Res Clin Pract 20 07, 76 :22 9 -23 5 87 ... K, Landen H: Effect of add-on acarbose to insulin therapy in routine clinical practice Clin Drug Invest 20 03, 23 : 621 - 627 Hakobyan et al Health and Quality of Life Outcomes 20 11, 9:83 http://www.hqlo.com/content/9/1/83...

Ngày tải lên: 20/06/2014, 15:20

... 828 ) c2 (4) c2 (1) c2 (3) a 7.6 0.8 6.8 1.46 0.81 09 b b b b b a p-value 1. 92 2.74 1.46 0.81 1. 92 2.74 540 07 14 20 09 07 14 20 1.45 2. 0 b 0.71 1.88 2. 27 1.45 0.71 1.88 2. 27 08 1 Males(n = 828 ) ... 794 24 .1** 2. 3 21 .9 1.35 10 -0.73 10 0.58 09 2. 84 25 1.08 10 -1.41 13 0.46 12 3.34 41 048/.360 15.8* 0.1 15.7 1. 52 -0.53 0. 42 2.96 1.53 -0.48 0.70 2. 84 000/ .20 2 12 09 08 26 13 08 10 30 1. 92 -0.40 ... most information regarding differences in depression levels in the vicinity of these cutoff points This information can be used to determine which items are the main indicators for distinguishing...

Ngày tải lên: 11/08/2014, 15:22

... diagnosing diabetes mellitus J Clin Endocrinol Metab 20 08, 93 :24 47 -24 53 46 International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes Diabetes Care 20 09, 32: 1 327 -1334 ... Curr Opin Clin Nutr Metab Care 20 02, 5:551-559 14 Marette A: Mediators of cytokine-induced insulin resistance in obesity and other inflammatory settings Curr Opin Clin Nutr Metab Care 20 02, 5:377-383 ... Manifestations of chronic disease during pregnancy Jama 20 05, 29 4 :27 51 -27 57 49 Kim C, Newton KM, Knopp RH: Gestational diabetes and the incidence of type diabetes: a systematic review Diabetes Care 20 02, 25 :18 62- 1868...

Ngày tải lên: 25/10/2012, 10:02

... 7.5 (27 .2) 4.3(15.4) 0.037 0.134 9 .2( 25.0) 0.1 42 0.054 4.7(-5.3 to 14.7) -1.7 (-15 .2 to 11.8) Bodily pain 72. 9 (21 .7) 67.0 (24 .0) 76.7 (20 .4) 73.3 (24 .2) 3.9 (20 .4) 6 .2( 18.9) 0.307 0.0 82 -2. 4(- 12. 5 ... K-H, Hu FB: Diabetes in Asia Epidemiology, risk factors, and pathophysiology JAMA 20 09, 301 :21 29 -21 40 Lim JG, Kang HJ, Stewart KJ: Type diabetes in Singapore: The role of exercise training for its ... functioning 84 .2( 22. 7) 83.8(16.8) 88.3(16.4) 87.5(13.9) 4 .2( 23.1) 3.8(11.9) 0.330 0.095 0.4(-9.1 to 10.0) 0.930 Role-Emotional 84.4(30.0) 87.8 (27 .0) 93.3(18.4) 90.0 (25 .0) 8.9 (24 .7) 2. 2 (23 .0)...

Ngày tải lên: 20/06/2014, 15:20

... 20 03 to 20 52 6000 5000 20 52 number 4000 20 03 3000 20 00 1000 0 10 20 30 40 50 age [yeas] Fig 16 Number of D2 patients from 20 03 to 20 52 60 70 80 90 100 Burden of Diabetes Type Through Modelling and ... prevalence of D2 model is shown in Fig 16 3.5 x 10 number of people from 20 03 to 20 52 2003 2. 5 1.5 20 52 0.5 0 10 20 30 40 50 60 age [years] 70 80 90 100 Fig 15 Number of people in Slovenia from 20 03 ... cleavage from the protein backbones AGEs involving protein cross-links include: pentosidine, a dimer of arginine and lysine; methylglyoxal-lysine dimer (MOLD), a dimer of two lysine residues; and...

Ngày tải lên: 27/06/2014, 18:20

... metformin 16 Role of the Adipocyte in Development of Type Diabetes effects (Tang et al., 20 01), acting as co-adjuvants in the reduction of the incident of diabetes (Doggrell, 20 02) , increasing vascular ... diabetes Thus, lipids in the liver link type diabetes to increased secretion of VLDL1 Another factor of importance is insulin Although insulin inhibits the assembly of VLDL1 in individuals with low ... highest insulin-dependent consumption of glucose and thus of major importance in the development of insulin resistance 34 Role of the Adipocyte in Development of Type Diabetes Fig The migration of...

Ngày tải lên: 27/06/2014, 19:20

... CSAs in the controls were 0.08 ± 0. 02 cm2 in the MA, 0.07 ± 0. 02 cm2 in the MB, 0.04 ± 0.01 cm2 in the UA, 0.10 ± 0.03 cm2 in the TA, and 0.04 ± 0.01 cm2 in the SA The CSAs was a significant increase ... shown in Table The CSAs in the patients with DM group were 0.13 ± 0.05 cm2 in the MA, 0.09 ± 0.03 cm2 in the MB, 0.0.7 ± 0. 02 cm2 in the UA, 0.18 ± 0.04 cm2 in the TA, and 0.05 ± 0.01 cm2 in the ... Salmeron, E., Lai, J., & Unwin, DH (20 01) A double-blind, placebo-controlled study of the use of amphetamine in the treatment of aphasia Stroke, Vol 32, No 9, pp 20 93 -20 98,1 524 4 628 (Electronic) Wall...

Ngày tải lên: 28/06/2014, 05:20

... 24 25 26 27 28 Adiposity and Diabetes in Older Adults Diabetes Care 20 04; 27 : 1375-1380 Bloomgarden ZT Adiposity and Diabetes Diabetes Care 20 02; 25 : 23 42- 2349 Kahn BB, Flier JS Obesity and insulin-resistance ... 22 .3 1.0 1.69 (1. 02- 2. 82) 2. 83 (1.71-4.69) 1.0 1.59 (0.95 -2. 66) 2. 55 (1. 52- 4 .28 ) 1.0 1. 52 (0.90 -2. 55) 2. 28 (1.35-3.85) WC (cm) ≤ 80 80.1-86.9 87.0-93.9 ≥ 94.0 6.6 14.1 19.0 24 .7 1.0 2. 31 (1 .29 -4. 12) ... Physiol 1990; 69: 20 04 -20 11 Selvin E, Coresh J, Brancati LB The burden and treatment of diabetes in eldely individuals in the U.S Diabetes Care 20 06; 29 :24 15 -24 19 International Diabetes Federation...

Ngày tải lên: 08/08/2014, 16:23

... People with Diabetes Mellitus in Trinidad Internal Journal of Epidemiology 1997, 26 (3): 620 -7 American Diabetes Association: Standards of Medical Care in Diabetes Diabetes Care 20 05, 28 (Suppl 1):4-36 ... 8.5 (0.3) 9.1 (0 .29 ) 8 .2 (0 .28 ) 9.3 (0 .29 ) 0. 025 29 .1 (0.66) 28 .8 (0.68) 27 .7 (0.58) 27 .8 (0.57) * Systolic BP (mmHg) 131.6 (2. 32) 136.5 (2. 43) 133.7 (2. 44) 126 .9 (1. 92) * Diastolic BP(mmHg) 85.6 ... (mg/dl) 21 4.3 (4.91) 21 4.4 (17.64) 23 2.7 (6.79) 21 7 .2 (8 .25 ) * Fasting Total Triglycerides (mg/dl) 156.8 (15.73) 1 52. 9 (10.33) 190.7 (23 .4) 195.6 (22 .87) * Random glucometer value (mg/dl) 179 .2 (9.06)...

Ngày tải lên: 11/08/2014, 07:21

... increased in obese men J Clin Endocrinol Metab 20 01, 86:1 921 -1 924 Page of (page number not for citation purposes) Theoretical Biology and Medical Modelling 20 09, 6: 12 23 24 25 26 27 http://www.tbiomed.com/content/6/1/ 12 ... metabolic syndrome, including visceral obesity, insulin resistance and dyslipidemia [25 ,26 ] In CGC, HSD11B2 is ranked tenth, obtaining 35.1 CGC points due to as much as nine matching keywords, although ... suggest an increased risk of type diabetes as a consequence of low adiponectin levels [24 ] In the CGC application, CDH13 obtains 38.9 points from only one single matching keyword ("adiponectin") However,...

Ngày tải lên: 13/08/2014, 16:21

... Care 20 10, 14:444 http://ccforum.com/content/14/5/444 Page of 22 07 patients admitted to medical ICU 385 with a history of DM, IFG or IGT 1 822 27 4 died in hospital 1548 screened 443 excluded - 21 1 ... participation - 20 3 terminally ill - 29 receiving corticosteroids 669 436 NORMOGLYCAEMIA HYPERGLYCAEMIA 76 excluded: - newly diagnosed DM, IGT or IFG 669 360 started follow-up 1 02 died 154 discontinued ... 14 DM 326 normoglycaemic finished follow-up 66 died 93 discontinued follow-up started steroid treatment 193 47 IGF / IFG 33 DM 113 normoglycaemic Figure Flow diagram showing the loss of patients...

Ngày tải lên: 13/08/2014, 21:21

... IN 47907 Department of Medicine, Division of Endocrinology, Indiana University School of Medicine, Indianapolis, IN 4 620 2   24     Abstract We examined the acute dose-dependent effects of intracoronary ... Svendsen2, Kieren J Mather3, Johnathan D Tune1 Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN 4 620 2 Weldon School of Biomedical Engineering, ... GLP-1 (9-36) increased coronary blood flow in canines (94, 110) There were also no increases in MVO2 in these other canine studies Acute infusion of GLP-1 (7-36) (10 pM/kg/min IV) into swine immediately...

Ngày tải lên: 24/08/2014, 12:16

... modulated by exercise 21 7.5 .2 KCNQ1 More recently in 20 08, two independent GWAS in Japan41, 42 identified SNPs (rs 223 78 92, rs 223 7895, rs 223 7897 and rs 228 322 8) within a novel T2DM susceptibility ... 0.001 Risk of T2DM [OR (95%CI)] 1.61 (1.10 -2. 33) 1.60 (1.09 -2. 32) 1.59 (1.09 -2. 32) 1.57 (1.08 -2. 25) 1. 52 (1.04 -2. 21) 1.63 (1.11 -2. 38) 1.53 (1.04 -2. 24) 1.60 (1.09 -2. 32) 1.57 (1.08 -2. 29) p-value*/p-value† ... 1-1-1-1-1-1-1-1-1; Haplotype 2: 2- 2-1 -2- 1-1-1-1-1; Haplotype 3 :2- 2 -2- 2 -2- 2 -2- 2 -2- 2 (where 1=common allele, 2= minor allele) *Adjusted for age and sex † Adjusted for age, sex, BMI Table 13 Haplotype effect...

Ngày tải lên: 14/09/2015, 08:48

... rs3 927 02 Exon 11 M4 rs731934 Intron 27 M 12 rs3814995 Exon M5 rs2071 327 Exon 26 M13 rs 228 5450 Exon M6 rs480 621 3 Exon 24 M14 rs401 824 Promoter M7 rs1040 929 9 Intron 23 M15 rs443186 KIRREL2 5'UTR ... exons 2- 21 codes for the region containing the Ig domains A fibronectin type III-like (FnIII) domain is encoded by exons 22 -23 while exon 24 codes for the helical transmembrane domain Exons 25 -29 ... insulin resistance in 128 offspring of T2DM patients compared to nine controls Offspring with strongly positive 100 kDa bands were more insulin resistant in terms of reduced rates of non-oxidative...

Ngày tải lên: 03/10/2015, 20:58

... meat intake, and the risk of type diabetes in women Arch Intern Med 20 04; 164 (20 ) :22 35 -22 40 Schulze MB, Manson JE, Willett WC, Hu FB Processed meat intake and incidence of Type diabetes in younger ... 2. 7 26 .2 23.6 14.0 24 .4 38.0 5.6 0.1 1.4 18.9 14.5 9.7 15.6 60 .2 9.1 0 .2 3.6 26 .1 19.8 12. 6 22 .3 45.3 6.4 0.7 1.6 21 .6 Int J Med Sci 20 06, 158 Table 2: Unprocessed meat intake and risk of type diabetes ... 1659.4 2. 8 2. 2 2. 2 2. 68 38.6 30.9 36.0 33.8 38.8 34.3 33.1 32. 3 23 .7 10.8 11.53 42. 3 30.6 15.5 36.1 34.3 21 .1 8.5 9.9 38.9 33.8 17.3 32. 7 31.8 22 .8 12. 6 18.4 38.3 29 .3 14.1 20 .2 38.8 24 .7 16.3...

Ngày tải lên: 31/10/2012, 16:49

... 20 02, 23 :599- 622 10 Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM: C-reactive protein, interleukin 6, and risk of developing type diabetes mellitus JAMA 20 01, 28 6: 327 -334 11 Ko K-P, Min ... 50-55 2, 753 (34%) 96 (16%) 28 (13%) 2, 657 (36%) 55-60 1,795 (22 %) 110 (18%) 38 (18%) 1,685 (23 %) 60-65 1,446 (18%) 122 (20 %) 45 (21 %) 1, 324 (18%) ≥ 65 2, 024 (25 %) 29 1 (47%) 1 02 (48%) 1,733 (24 %) ... contributed to inconsistent findings For instance, the interquartile range for NO2-exposure in this study was only 2. 3 μg/m3, while in previous studies on air pollution and type diabetes [2, 3] this...

Ngày tải lên: 06/03/2014, 19:20