environmental presence and persistence of pharmaceuticals an overview

... Gd–DTPA2– and Gd(HP-DO3A) produced no lethality up to 200 g/L, and Gd(CPA-DO3A)– produced lethality of 17% and 31% at 24-hour exposures of 100 g/L and 200 g/L.34 The toxicity of metals and their ... elegans as an alternative animal species, J of Toxic Environ Health, Part A, 61, 641, 2000 35 Sun, H., Wang, X., and Wang, L., Bioconcentration of rare earth elements lanthanum, gadolinium and ... V., 1988 28 Environmental Assessment Technical Assistance Handbook: Technical Assistance Document 4.02: Microbial Growth Inhibition, Food and Drug Administration, 1987 29 Hoffmann, J and Viedt,...

Ngày tải lên: 18/06/2014, 16:20

... Reactions of VX, GD, and HD with nanosize CaO:  autocatalytic dehydrohalogenation of HD J Phys Chem B 2000, 104:5118-5123 Jang HD, Kim SK, Kim SJ: Effect of particle size and phase composition of titanium ... different samples of nanoparticles with concentrations of 0.427 and 4.27 mM iron The relaxivities   of nuclear spins in an aqueous solution of magnetic    Tim  nanoparticles can be expressed ... were measured using an MRI scanner in the aqueous solutions of various concentrations of nanoparticles ranging from 0.427 to 4.27 mM The T1 and T2 relaxivities were 1.139 and 1.115 (mM·s)−1,...

Ngày tải lên: 20/06/2014, 23:20

... not required the use of any toxic organic solvent and surfactant The drug and the polymer of interest are solubilized in a supercritical fluid, and the solution is 11 expanded through a nozzle ... 180mm and slice thickness = 5mm The values for TR and TE of the IOs and the IO-loaded PLGA-mPEG nanoparticles to obtain r1, r2 and r2* relaxivities were given in Table 3.1 Table 3.1 The TE and ... targets to allow for earlier recognition and characterization of disease, earlier and direct evaluation of treatment outcomes, and a deeper understanding of disease development, there is a need...

Ngày tải lên: 06/10/2015, 21:15

... GS, and TT designed the study YY and TT contributed to recruitment of study subjects and MRI data collection HM and TT were involved in clinical evaluation of the participants and procedures of ... significant http://www.annals-general-psychiatry.com/content/7/1/25 and refined the analyses YY, GS, and NT wrote the manuscript All the authors read the paper and approved the final form of the manuscript ... volumes of grey and white matter, CSF, and whole brain (grey and white matter plus CSF) were calculated and compared across groups using independent t tests with the level of significance set...

Ngày tải lên: 08/08/2014, 23:21

... score of and were collapsed to 0, the original scores of and were collapsed to 1, and the original scores of 4, 5, and were considered 2, 3, and 4, respectively Cartilage loss was defined as an ... 20) and interday (n = 200) coefficients of variance for each biomarker are, respectively, 10%–17% and 14% for C2C, 5%–14% and 13% for C1,2C, 4%–12% and 12% for CS 846 epitope, and 11%–18% and ... plates (anterior, central, and posterior femur; anterior, central, and posterior tibia; and medial and lateral patella) using the Whole Organ Magnetic Resonance Imaging Score (WORMS) semiquantitative...

Ngày tải lên: 09/08/2014, 10:21

... endocrine and exocrine glands, consisting of the islets of Langerhans and the pancreatic acini, respectively Pancreatic islets are small organ-like entities dispersed throughout the pancreas at ... background noise and produces images of high spatial and temporal resolution As we learn more about the biological mechanisms of major killers such as cancer, heart failure and diabetes and their mutual ... physics and engineering of imaging techniques and instruments, [2] the chemical and materials science needs for designing imaging probes and contrast agents, and [3] the biological questions to be answered...

Ngày tải lên: 11/09/2015, 10:01

... available with standard and polarised light and images captured and digitised using a closed-circuit television and Image Grabber software (Neotech Ltd, Hampshire, UK) R62 A semiquantitative scoring ... Ayad, Manchester, and A Kwan, Cardiff, for the provision of antibodies to collagen types VI and X, respectively; to Professor B Caterson, Cardiff, for all the proteoglycan antibodies; to Mrs Janet ... classified as fibrocartilage when bundles of collagen fibres were randomly organised and the cells were more elongated and often more numerous Vascularisation and mineralisation were identified on...

Ngày tải lên: 09/08/2014, 01:21

... structure of chitosan and modified chitosan Chemical structure of chitosan and modified chitosan Page of (page number not for citation purposes) Journal of Nanobiotechnology 2008, 6:1 http://www.jnanobiotechnology.com/content/6/1/1 ... morphology and ξ-potential analysis of MCIOPs The size and morphology of IOPs and MC-IOPs were observed by TEM (JEM-1230, JEOL, Japan) and HRTEM (QUANTA 200F, FEI, USA) The sample for TEM analysis ... skeleton The characteristic bands of modified chitosan, amide I, II, and III were shifted 1623, 1510 and 1464 cm-1 due to interaction with IOPs Shifting of such amide bands from higher to lower...

Ngày tải lên: 11/08/2014, 00:22

... and face, and a right homonymous hemianopia His vascular risk factors included a 25 pack-year smoking history and a previous myocardial infarction An initial computed tomography (CT) head scan ... (STA-MCA) anastomosis The EC/IC bypass study was a large multicenter randomized trial of STA-MCA anastomosis with primary end-points of 30-day stroke mortality and stroke incidence A total of 1377 ... UK Authors’ contributions AG, OD and SM reviewed our patient’s case notes and the current literature on cerebral misery perfusion and drafted the manuscript SG and DA conducted the BOLD-MRI imaging,...

Ngày tải lên: 11/08/2014, 11:23

... duration and time between MRI and ROSC in both groups were compared by t-test and severe disability) were grouped as unfavourable outcomes; and the GOS scores of and (moderate disability and good ... than 80% of normal may indicate a cortical laminar Page of 11 necrosis or an irreversible tissue injury and this may well predict an unfavourable outcome The degree of the changes of the DWI and ... outcome of comatose survivors after out -of- hospital cardiac arrest • The cortex and basal ganglia were predominantly damaged in the patients, and in particular, the Rolandic, parietal, and occipital...

Ngày tải lên: 13/08/2014, 20:21

... (SBIC) of the Agency for Science, Technology and Research (A*STAR) First of all, I would like thank Professor Wang Shih-chang and Professor Teoh Swee Hin for their supervision and guidance throughout ... Jerry Chan for his tireless inspiration, patience and hands-on approach to the guidance of this thesis The overseas collaborators of this study, Professor André Briguet, Dr Olivier Beuf and Dr ... glial cells of the CNS, and they form a major part of the blood brain barrier and provide metabolic support of neurons Upon recognition of foreign antigen with PRR such as TLR, mannose and complement...

Ngày tải lên: 14/09/2015, 08:49

... includes an internal stainless steel section, wrapped in polyethylene fibers, as well as an external section made of 26 expandable nickel and titanium spirals, with an initial diameter of 0.8 mm, ... this leads to the fastening of implants and to an occlusion of the tubarian lumen, thus enabling definitive contraception [8] The security of performing MRI on a woman using Essure® has raised ... made of soft and flexible plastic, with no metallic components, located inside an application system, which allows for the subcutaneous placement of the implant in the internal surface of the...

Ngày tải lên: 13/02/2014, 07:20

... the third and fourth parvocellular layers (Calkins & Hendry, 1996) Layers and have on-center receptive fields, and layers and have off-center receptive fields Layers and have both on- and off- center ... thanks to the continued joint efforts of governmental, industrial and academic institutions globally Regardless of the MRI systems and the brands used, one should always be able to understand and ... significantly correlated Within each region of statistical significance, local maxima of signal increase (the voxels of maximum significance) and their location can be expressed in terms of x, y, and...

Ngày tải lên: 19/02/2014, 23:20

... the assistance of SE The mouse model was designed and developed by SLA MRI methods were validated by UAR and SLA, interpretation of MR images was done by JH and SLA and quantification of tumor ... Transplantation Laboratory, Haartman Institute and Finnish Institute of Molecular Medicine, University of Helsinki, Finland 2HUSLAB, Helsinki University Central Hospital, Finland 3Department of ... vein of NMRI nude mice After 48 hours, mice (n = in each group) were sacrificed and organs and tumors were harvested for luciferase analysis To separate between tumors and organs, tumor tissue and...

Ngày tải lên: 18/06/2014, 16:20

... manuscript Particularly, WCWC and BKWN carried out the analysis of data and wrote the manuscript; AML and TPL contributed to the editing of the manuscript, clinical recruitment and assessment; WWML participated ... coronal planes so that motions of the chest wall and diaphragm could be assessed The chest wall and diaphragmatic motions were measured in antero-posterior, left-right and cranio-caudal directions respectively ... after operation, the median correction rate of Cobb's angle was 60% (range 42% to 72%) The median Cobb's angle changed from 59° to 24° while the sagittal Cobb's angle changed from 19.1° to 23.1°...

Ngày tải lên: 20/06/2014, 01:20

... Figures 5(b) and 5(c), 6(b) and 6(c), and 7(b) and 7(c) Surprisingly, the FLDA and SVM significantly improved classification results where WM, GM, and CSF were EURASIP Journal on Advances in Signal ... GM, and CSF are also shown in Figures 12(b) and 12(c), 13(b) and 13(c), and 14(b) and 14(c) where both classifiers used the same 20 training samples selected for each of three substances and background ... Soltanian-Zadeh, J P Windham, D J Peck, and A E Yagle, “A comparative analysis of several transformations for enhancement and segmentation of magnetic resonance image scene sequences,” IEEE Transactions...

Ngày tải lên: 21/06/2014, 22:20

... duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage 12345 Moeller, Sectional Anatomy © 2007 Thieme All rights reserved Usage subject to terms and ... subject to terms and conditions of license V Dedicated to our parents, Alfred and Friedel Möller and Emil and Edith Reif, in love and gratitude Moeller, Sectional Anatomy © 2007 Thieme All rights ... in MRI and CT visualization of the vascular system have also further improved For example, stepwise shifts of the table top have become standard procedures in angiography of the pelvis and leg...

Ngày tải lên: 29/06/2014, 09:21

... Moeller, Sectional Anatomy © 2007 Thieme All rights reserved Usage subject to terms and conditions of license 165 166 MR Angiography of the Splenic and Portal Veins Moeller, Sectional Anatomy © 2007 ... Jejunal and ileal veins Moeller, Sectional Anatomy © 2007 Thieme All rights reserved Usage subject to terms and conditions of license 167 168 MR Cholangiopancreatography Moeller, Sectional Anatomy ... Cardiac part of stomach (cardiac orifice) 22 Diaphragm (lumbar part) 23 Splenic artery and vein 24 Adrenal gland 25 Left kidney 26 Intertransversarii muscles (lateral lumbar) 27 Renal artery and vein...

Ngày tải lên: 29/06/2014, 09:21