entering the exciting world of 3d models

... Z-score distributions of the final models can be used together to evaluate the ability of the model to distinguish true sites from the background We evaluate the separation between the positive and ... SeqFEATURE models ranked by AUC The sensitivity of these models is, in general, very high, especially at the default 99% specificity Z-score cutoffs Even at 100% specificity over half of the models ... and the Z-score and associated sensitivity for 95% The final column reports the number of positive examples of the one-dimensional motif found in the ASTRAL40 compendium of the PDB Predictions of...

Ngày tải lên: 14/08/2014, 08:20

... discusses these challenges in the context of the twenty-first century “new” economy from the perspectives of the working CFO rather than the textbook CFO Why the new economy? And what’s wrong with the ... 1:1, with the higher the better The greater the margin of current assets over current debt, the better the position of the company For example, $4 million of assets compared to $2 million of liabilities ... 107 or 108 of the 1976 United States Copyright Act, without either the prior written permission of the Publisher, or authorization through payment of the appropriate per-copy fee to the Copyright...

Ngày tải lên: 18/12/2013, 09:12

... unsupervised algorithms The purpose of this paper is an analysis of the underlying probabilistic models and the types of errors committed by each one Furthermore, it is investigated how the decision threshold ... say that our models describe the process of word generation from the left to the right by alternately using two dice, the first for deciding whether to place a morpheme boundary in the current ... boundaries than in the opposite direction with a net increase of 0.0819 of correct boundaries which led to the increased recall Since the deduction of precision is less than the increase of recall, a...

Ngày tải lên: 20/02/2014, 04:20

Ngày tải lên: 21/02/2014, 12:20

... appeared in the analysis of both parts of the animal, with a major presence of bands in the body (upper part) versus the crown (lower part) In Fig 3, we show, in the uncombined (Fig 3A,B) or in the combined ... to hydrolyze the first of such C-terminal residues, glutamic acid, even after 60 of incubation Again, the addition of rPCI prevented any kind of hydrolysis by the enzyme The release of a glutamic ... the MS spectrum and capturing the MCP in the body extract The control spectra, as well as the ‘perturbed’ one (by rPCI addition, followed by removal of the captured targets by sedimentation of...

Ngày tải lên: 07/03/2014, 02:20

... of time Other than the chemical and physical properties of the polysaccharides, the genetic involvements of the biosynthetic processes which imparts specificity to the structure and thereby its ... importance of dietary fibres for availability of nutrients is presented in the next chapter The section ends with the advantages of starch as a source of energy Modification of the properties of starch ... with virus, starts off this section The next three chapters are devoted to the use of polysaccharides as carriers of drugs The first of these, (chapter 21) deals with the use of beta glucans as...

Ngày tải lên: 31/03/2014, 19:20

... 1.1 The process is initiated at the top left of the Vee with the definition of the operational need of the stakeholders The focus of the decomposition and definition process (or design) is the ... with the identification of the need for the system and progressing through the retirement of the system Some of the phases of the life INTRODUCTION TO SYSTEMS ENGINEERING Identification of Need ... or qualification of both the elements of the system and the system itself to ensure that the system meets the ultimate needs of the stakeholders 1.2 OVERVIEW OF THE ENGINEERING OF SYSTEMS This...

Ngày tải lên: 03/04/2014, 12:22

... manuscript, the introduction of this technique to the scriptorium at Saint Martial With this system of writing, combined with the use of the custos at the end of the line to show the pitch of the first ... to work on the other libelli of the volume The production of the codex halted precipitously, however, towards the end of the libellus of Proper tropes, with a significant portion of the manuscript ... take the reader to all parts of the edition where information is to be found on it with equal facility Here are the sections of the edition I Tropes of the Proper of the Mass II Office for the...

Ngày tải lên: 04/06/2014, 15:23

... or the other half of the jewel, leaving a perfect impression on the other side The electron microscope reveals a projection at the base of each spore’s footprint the decisive signature of the ... from the rest of the spore By this device, water condenses in two separate areas on the spore surface: one covering most of the spore, the other situated on its hump Swelling of the drop on the ... an important theme in the evolution of false truffles and other gasteromycetes is the gradual loss of the unfolding capacity of the fruiting body This results in the production of spores within...

Ngày tải lên: 11/06/2014, 00:23

... discusses these challenges in the context of the twenty-first century “new” economy from the perspectives of the working CFO rather than the textbook CFO Why the new economy? And what’s wrong with the ... 1:1, with the higher the better The greater the margin of current assets over current debt, the better the position of the company For example, $4 million of assets compared to $2 million of liabilities ... 107 or 108 of the 1976 United States Copyright Act, without either the prior written permission of the Publisher, or authorization through payment of the appropriate per-copy fee to the Copyright...

Ngày tải lên: 28/06/2014, 20:20

... many people thought that Lam triet’s painting was an attempt to feel the pulse of the world, accompanying the deep rhythms of the universe However, it was perhaps a mistaken conception Lam Triet’s ... vitality Though his paintings were then chockfull of detail, their colors were sparkling, dreamy and tranquil The outlines of his paintings at that time either concentrated on heavy-looking diamond ... in its library, a distant dream for a few good Vietnamese painters on the territory of the U.S Since then, he has spent most of his time living in Ho Chi Minh City and continued putting paintbrush...

Ngày tải lên: 29/06/2014, 06:20

... cavities Finally, they observed reduction in the levels of macrophage cytokines that had not been reported by the other groups Reconciling the results The existence of several knockouts of the same gene ... of the inflammatory response after the uptake of apoptotic cells Henson’s group used phage display to clone the antigen recognized by one of these antibodies, mAb 217 [4] They reported that the ... researchers in the field about how to interpret the results Simon Brown of the University of Edinburgh, UK, urges readers to focus on the commonality of the three studies “All three found the homozygous-null...

Ngày tải lên: 06/08/2014, 18:21

... amount of data and type of prior, i.e the more data are available the less are the estimates of responses influenced by the choice of priors And similarly for the variances of the estimate, they ... decreasing function of the degree of overlap between generations, or of the degree of connectedness of the data Obviously, when generations not overlap the situation is that of design 1, with no ... here for the sake of completeness, and the derivation of the estimator of is detailed in the Appendix Using Thompson’s notation, n unrelated males (n > 2) are measured for the trait of interest...

Ngày tải lên: 09/08/2014, 18:21

... occurs in the sarcin/ ricin hairpin of the 23S rRNA and in the loop E of the eukaryotic 5S rRNA) In the example shown in Figure 1a, an internal loop of the secondary structure forms a set of non-Watson-Crick ... sequential order of the usually observed set of non-Watson-Crick pairs is maintained, thereby defining a module The structure of the G-bulged module shown is from helix H11 of the 23S rRNA of Escherichia ... helical stems The structure of the G-bulged module shown is the one at the junction of helices H16-H21-H22 from the 23S rRNA of Escherichia coli (PDB code 2AW4) [10] Drawings courtesy of Jose Almeida...

Ngày tải lên: 09/08/2014, 20:21

... hmmalign of the HMMer package [66] and the logo was created using WebLogo [67] The logo displays the frequencies of amino acids at each position of the MADS domain, as the relative heights of letters, ... letters, along with the degree of conservation as the total height of a stack of letters, measured in bits of information The conserved motif KR[K/R]X4KK, which serves as part of the nuclear localization ... [5,8] The type I proteins have no K domain (Figure 1b) The type I MADS-domain proteins of plants can be further subdivided into the three groups Mα, Mβ and Mγ on the basis of their phylogeny and the...

Ngày tải lên: 09/08/2014, 20:22

... of the nature of the transactions They signed disclaimers that state clearly that they were not relying on us They state clearly that they knew what the risks of the trades were They signed the ... It allowed them to use the lack of transparency to make money from their clients and each other The emergence of swaps and the OTC markets changed the dynamics of derivatives forever The exchanges ... went up they would go back to borrowing on a floating rate basis In other words they would lose the protection of having fixed their cost of borrowing just when they needed it most On the other...

Ngày tải lên: 01/11/2014, 19:13

... increased, and the market price of the loans fell to only a fraction of their initial value The banks had to write down the value of the loans, which decreased the strength of their balance sheets ... profitability By expanding the amount of money they could trade and lend, banks could boost their profits, as long as the additional uses of money yielded higher returns than the costs of the ... MAKERS THE ROLES OF INVESTMENT BANKS Investment banks play critical roles in nearly every aspect of the economy They are both the brokers and bankrollers of the business world and, recently, of the...

Ngày tải lên: 03/11/2014, 17:00

... The story of material origins is not the story the text is telling here The authors, under the guidance of the Holy Spirit, have told the part of the story that is most significant to them (the ... sider the scenario of Moses sitting down with the elders of the people on the eve of the tabernacle dedication at the foot of Sinai He is trying to help the Israelites understand the gravity of ... claim The creatures of the sea were in a liminal zone in the ancient Near East After all, the sea was the very embodiment of non-order Therefore, there would be questions about the functions of the...

Ngày tải lên: 08/06/2015, 17:26

... in the way that the largest 60 nations of the world are integrating with the global economy (relative to their gross domestic product (GDP)) In addition, the index identifies the key drivers of ... Until 2008, the phenomenon of globalization seemed incontrovertible Although countries around the world adopted different models and approaches to their engagement with the world economy, the trend ... perspectives of their people These are the companies that will emerge as the sustainable leaders in this century.” Much of the international expansion planned will come in the form of foreign direct...

Ngày tải lên: 06/12/2015, 23:09

... 3, 16, 17), the rate of MACE ranged from 3.1%,to 12.8%, at the end of the two-year period In our trial, however, the incidence of MACE in the ZES treated group was 10% at the end of the two year ... been examined in the first four trials of the ongoing ENDEAVOR clinical trials program The results of these initial trials indicate that the ZES is safe and reduces the rates of clinical and angiographic ... showed a MACE rate of 17.8% at the end of the two-year follow-up, the MACE rates for the TAXUS trials ranged from 3% in TAXUS I trial (5) to 29% in the TAXUS III trial (7) The TAXUS IV trial...

Ngày tải lên: 25/10/2012, 11:18