enos+as+a+bipolar+molecular+switch

... regions has also suggested that NF-jB might be regarded as a signal transducer that transmits transient synaptic signals to the nucleus and has a role in behaviour, learning and memory formation ... glutamate receptors activates transcription factor NF-kappa B in primary neurons Proc Natl Acad Sci USA 92, 9618–9622 Lilienbaum A & Israel A (2003) From calcium to NF-kappa B signaling pathways ... ¨ A et al (2006) NF-kappaB regulates spatial memory formation and synaptic plasticity through protein kinase A ⁄ CREB signalling Mol Cell Biol 26, 2936–2946 Kassed CA, Willing AE, Garbuzova-Davis...

Ngày tải lên: 07/03/2014, 03:20

... results Stoichiometry (native ESI-MS) Average mass calculated (Da)b Mass measured LC-ESI-MS Mass measured ESI-MS (native) (Da) a W15-peptide TQAKRKKSLAMA [30] ine c As previously measured [31] b R77L ... increased between and m urea and later decreased again between and m urea A clear shift in maximal emission wavelength (MEW) between the native and the fully denatured state (0 and m urea) was ... trifluoroacetc acid and acetonitrile) of a typical LC-MS approach, we observed only PKG monomers Their molecular masses could be measured with an accuracy of a few Daltons, as depicted in Table For all...

Ngày tải lên: 07/03/2014, 09:20

... compilation ª 2006 FEBS 329 Molecular construction kit based on S-layers U B Sleytr et al of archaeal cell envelopes, as the latter are composed of a cytoplasmic membrane and a closely associated ... biologically based fabrication technology for the self-assembly of molecular catalysts, templates and scaffolds for the generation of ordered large-scale nanoparticle arrays for applications in ... also lead to a change in the lattice type At the molecular level, S-layer variation in G stearothermophilus PV72 was found to be based on DNA rearrangements between the chromosome and a naturally...

Ngày tải lên: 16/03/2014, 12:20

... translational regulation, rate of turnover, subcellular localization, or association with as yet undefined regulatory factors The most abundant nucleoside kinase in mammals, AK has emerged as a key ... PAGE (15% acrylamide) and PhosphorImager analysis To calculate reaction stoichiometries, radiolabeled reaction products and radioactive standards were quantitated using IMAGEQUANT software (Amersham ... quantification purposes Recombinant mAK-S standards have a higher apparent molecular weight than mAK-S in the sample lanes due to N-terminal polyhistidine tags Quantification of relative AK abundance...

Ngày tải lên: 16/03/2014, 18:20

... TGTAAAG TGTAAAG + ) + )95 )1100 )1470 ACACacG ACACttG ACACaaG + + + + ) ) ) ) ) )140 )1100 )1596 )1632 )140 )1100 )1596 )1632 )1874 CAaaTG CAagTG CAaaTG CAaaTG CAaaTG CActTG CAttTG CAgtTG TGAGTCA ... peptide was constructed as follows The DNA fragment was amplified from GmPDIM cDNA by PCR using the primers 5¢-GACGACGACAAGATGC ACGCACTCTATGGAGC-3¢ and 5¢-GAGGAGAAGC CCGGTTCATAGCTCATCCTTGCTTGAAG-3¢ ... soybean cotyledons during maturation (A) GmPDIM mRNA was quantified by real time RT-PCR Each value was standardized by dividing the value by that for actin mRNA Values are calculated as a percentage...

Ngày tải lên: 30/03/2014, 04:20

... purchased from Takara (Kyoto, Japan) and Toyobo (Osaka, Japan), respectively QuikChange XL Site-Directed Mutagenesis Kit was from Stratagene (La Jolla, CA, USA) Construction of plasmids A BamHI ... plasmid, pSVLfLuc plasmid was cotransformed with hIZA1s expression vectors and Renilla luciferase vector as an internal standard The promoter activity of pSVL was normalized to Renilla luciferase ... Materials A plasmid containing hIZA1 cDNA (IMAGE clone, No 5300612) and a transfection reagent, lipofectamine 2000tm, were purchased from Invitrogen (Carlsbad, CA, USA) pGEX-6p-3 vector was from Amersham...

Ngày tải lên: 30/03/2014, 11:20

... ST and pharmaceutical nicotine in a regulatory, legal and social context further suggests that the potential of ST as a cessation aid has been under-realized Nicotine gum and the nicotine patch ... documents that switching to ST compares very favorably with pharmaceutical nicotine as a quit-smoking aid among American men, despite the fact that few smokers know that the switch provides almost all ... just as likely to cause cancer as smoking cigarettes [20] These findings are in direct contrast to the general agreement among tobacco research and policy experts that ST use is far less hazardous...

Ngày tải lên: 11/08/2014, 18:20

... central NOD (NACHT) domain has ATPase activity and facilitates self-oligomerization At the amino-terminal a protein-protein interaction mediating caspase-recruitment domain (CARD) is localized ... J: MORAXELLA CATARRHALIS INDUCES INFLAMMATORY RESPONSE OF BRONCHIAL EPITHELIAL CELLS VIA MITOGEN-ACTIVATED PROTEIN KINASE AND NF{kappa}B ACTIVATION AND HISTONE DEACETYLASE Page 15 of 17 (page number ... 434:243-249 Uematsu S, Sato S, Yamamoto M, Hirotani T, Kato H, Takeshita F, Matsuda M, Coban C, Ishii KJ, Kawai T, Takeuchi O, Akira S: Interleukin-1 receptor-associated kinase-1 plays an essential role...

Ngày tải lên: 12/08/2014, 16:20

... human as well as macaque monocyte-derived DC and macrophages Our data suggest that LMP1 and LMP1-CD40 significantly enhance the ability of SIV to activate DCs and macrophages SIV-LMP1 also enhances ... system [30,31] Finally, the use of the nonhuman protein LMP1 as a molecular adjuvant may actually be advantageous compared to human-derived molecular adjuvants such as CD40, for example, by lowering ... (GraphPad Software, La Jolla, CA) and expressed as the mean ± SEM Statistical comparisons were analyzed by Student’s t test A p-value of 0.05 was chosen for statistical significance Additional...

Ngày tải lên: 13/08/2014, 01:20

... Figure A: original data B: normalised data C: standardised data D: data after factor correction Note that normalisation, standardisation, and factor correction reduce the variation within each condition ... rection Comparison of normalisation, standardisation and factor corComparison of normalisation, standardisation and factor correction Mean (and SEM) of the data of the molecular- biology data set from ... approach assigns part of the variation to the estimated session factors The ratio approach can be seen as a special case, in which the user assumes that the multiplicative factor is the same for...

Ngày tải lên: 13/08/2014, 09:21

... quinquefasciatus quinquefasciatus quinquefasciatus quinquefasciatus quinquefasciatus quinquefasciatus quinquefasciatus quinquefasciatus quinquefasciatus quinquefasciatus quinquefasciatus Identity ... of diseases such as malaria on individuals and nations within malaria endemic areas, if such nanoparticles are shown by trials to have promise for eradicating malaria, it may be justifiable to ... Nucleic Acids Research 2008, 36(8):2630-2638 Altschul SF, Madden TL, Schäffer AA, Zhang J, Zhang Z, Miller W, David J, Lipman DJ: Gapped BLAST and PSI-BLAST: a new generation of protein database search...

Ngày tải lên: 13/08/2014, 16:20

... CS at workplaces was analysed with quantitative and qualitative approaches Based on a framework adapted from Gumperz [26] and Auer [3], the functions and motivations for CS were identified and ... questionnaire was made Because the well planned and structured questionnaire was used to get a reliable data, the reliability and validity of the questionnaire was also determined 3.8 SUMMARY CHAPTER ... Intrasentential versus Intersentential Code-switching Language alternation within a sentence is known as intrasentential CS while language alternation across sentence boundaries is known as intersentential...

Ngày tải lên: 02/12/2015, 12:43

... packages có tên samba rpm –qa samba* => liệt kê packages có tên bắt đầu samba rpm –qa | grep samba => liệt kê packages có tên ch a samba rpm –qd samba => liệt kê files tài liệu liên quan đến samba ... a Cao, Q.1, TP.HCM Tel: (84-8) 38244041 – 0989012418 www.athena.edu.vn - Bạn liệt kê danh sách packages cài đặt (Installed packages) danh sách packages dùng cho bạn download (Available packages) ... (configuration) liệt kê tập tin cấu hình package 3/ Gở bỏ package (Erase): Chú ý: Nếu gỡ bỏ package mà package phụ thuộc vào package khác gỡ bỏ ta dùng thêm tuỳ chọn nodeps  Lỗi package samba-3.0.23c-2.rpm...

Ngày tải lên: 13/09/2012, 10:21

Ngày tải lên: 04/10/2012, 10:24

... Cochran-Armitage trend test was performed in order to test if a gradual increase in sickness absence was associated with increase in risk of disability pension The SAS procedure PROC GENMOD (SAS ... than days of absence per annum decreased from 2.77 to 2.68, and remained significant There was an increased risk of disability pension for people who were smokers at baseline, whereas there was ... was stronger among men (OR=3.13) than among women (OR=2.19) (Table 2) Additional analysis treating days of sickness absence during 1990 as a continuous variable showed a clear trend of increase...

Ngày tải lên: 26/10/2012, 10:03

... mammalian hosts These animals, usually pigs, act as a transformer or converters; creating a strain that can more readily infect humans Pigs can be infected with both avian and human influenza A ... horses, seals, whales, and many types of birds as well as humans This can be a trans-species virus Type B infects only humans [8] Animals act as reservoirs for this influenza virus and Gelbalt [7] ... as a protease to cleave HA which creates a systemic infection as well [1] Taubenberger [1] reported that this transformation was not observed in the1918 strain, or in strains “captured” in nature...

Ngày tải lên: 02/11/2012, 11:12

... straight away without stopping at a petrol station After having talked and talked and talked, and when I finally managed to dismiss her with fake half-promises and sat back into my car at last ... I knew it wasn’t so A more ominous explanation came to my mind Maybe everything was real, and it was taken for granted that I was dead, just I wasn’t! My brain was still working, and I would ... body Admiration and even something like awe Was he awed because she was dead, by the mystery of death? No, he was awed because in his eyes she was beautiful, a beautiful young woman… For a split...

Ngày tải lên: 07/11/2012, 09:08

... 2005), he also makes a distinction between task-based teaching and tasksupported teaching The task-based teaching occurs when the teaching is based exclusively on meaning-focus tasks, and the task-supported ... functions and language notions are taught to learners at the same time with the assumption that language learning relates to learning formulaic expressions of language as well as learning rules of language ... II.1 A review of language teaching approaches Teaching language has received much focus for the past few decades So many approaches and methods such as Audiolingual Method, Total Physical Response,...

Ngày tải lên: 07/11/2012, 14:44

... pleasantness ratings, the aroma concentration had a similar effect on both age groups in the first tasting session: the heightened aroma sample was rated as less pleasant than the regular aroma sample ... Preliminary data analysis revealed no significant main effects and only one significant interaction of day and aroma on the pleasantness ratings of the young, implicating an increase in pleasantness ... a small food reward after the last evaluation session Samples The sample material was a fermented oat bran product (Yosaw, Bioferme, Finland), which is a cereal-based snack food similar to flavored...

Ngày tải lên: 03/04/2013, 21:06

... BA R = B B A where AUC is the area under the curve Statistical analysis All data are presented as a mean value with its standard deviation indicated (mean ± SD) Statistical analysis was conducted ... (Mw = 200,000) was purchased from Hayashibara (Tokyo, Japan) Epirubicin·HCl (EPI·HCl) was purchased from Hisun Pharmaceutical Co (Zhejiang, China) Poly (vinyl alcohol) (PVA) with an average molecular weight ... main pharmacokinetic parameters were calculated by DAS 1.0 (Anhui, China) program Bioavailability (BA) is a measurement of the rate and extent of a therapeutically active drug that reaches the...

Ngày tải lên: 23/04/2013, 21:38