... (radioimmunotherapy) while sparing normal cells [8284] At present, MUC1 and MUC16 are the best and only characterized mucins and monoclonal antibodies against MUC1 and MUC16 are under preclinical and ... use of mucins as targets for radioimmunodiagnosis and radioimmunotherapy is also being explored and appears to be a potential approach for the diagnosis and treatment of ovarian tumors which overexpress ... serine, threonine, and proline in their backbone Serine and threonine are sites for O- and N-glycosylation Presence of the tandem repeat domain which varies in number, length and O-glycosylation...
Ngày tải lên: 20/06/2014, 07:20
... Pediatric Epilepsy Diagnosis and Therapy Third Edition Pediatric Epilepsy Diagnosis and Therapy Third Edition EDITORS JOHN M PELLOCK, MD Chairman, Division ... Brain: Cells, Synapses, and Circuits Libor Velíšek and Solomon L Moshé Ion Channels, Membranes, and Molecules in Epilepsy and Neuronal Excitability Laxmikant S Deshpande and Robert J DeLorenzo ... D Bourgeois and Raman Sankar 40 ACTH and Steroids Rajesh RamachandranNair and O Carter Snead, III 543 41 Benzodiazepines Kevin Farrell and Aspasia Michoulas 557 42 Carbamazepine and Oxcarbazepine...
Ngày tải lên: 12/08/2014, 05:21
Pediatric Epilepsy Diagnosis and Therapy - part 4 pot
... Paediatr Scand 1960; 49:572–582 Druckman R, Chao D Massive spasms in infancy and childhood Epilepsia 1955; 4:61–72 Gibbs EL, Fleming MM, Gibbs FA Diagnosis and prognosis of hypsarrythmia and infantile ... marked and rapid progress in the understanding of the cellular mechanisms producing SMEI, there is thus still ample room for further research Diagnostic Evaluation and Differential Diagnosis The diagnosis ... and adult patients with SMEI sleep without soft cushions, and we also recommend that febrile episodes be treated as early as possible Course and Prognosis Introduction and Definition SMEI stands...
Ngày tải lên: 12/08/2014, 05:21
Pediatric Epilepsy Diagnosis and Therapy - part 5 docx
... motor and hand skills and loss of communication and cognitive functions between and 30 months Of particular significance is the loss of acquired speech Deceleration of head growth, stereotypic hand-wringing ... anticonvulsant and antiepileptogenic properties, and it may normalize EEGs It is well known that carbamazepine may worsen the generalized epilepsies and may even worsen focal spike -and- wave discharges and ... Lennox-Gastaut type and are less discrete in time, longer, and with slower and more polymorphic spike-wave complexes on EEG Absence seizures are the defining and predominant seizure type in CAE and juvenile...
Ngày tải lên: 12/08/2014, 05:21
Pediatric Epilepsy Diagnosis and Therapy - part 6 ppt
... the concept of monotherapy and sequential monotherapy gained wide acceptance in the late 1970s and early 1980s, because the frequent negative impact of polytherapy on the number and intensity of ... antiepileptic and neurotoxic interactions between many of 32 • COMBINATION DRUG THERAPY: MONOTHERAPY VERSUS POLYTHERAPY the established and newer AEDs, including interactions between drugs and their ... neonates and small infants, is mandatory Optimal oxygenation and expectant observation and treatment for hyperthermia and other medical complications lead directly to a lessening of morbidity and...
Ngày tải lên: 12/08/2014, 05:21
Pediatric Epilepsy Diagnosis and Therapy - part 7 pps
... DRUGS AND KETOGENIC DIET 40 ACTH and Steroids Rajesh RamachandranNair O Carter Snead, III he efficacy of adrenocorticotropin (ACTH) therapy in childhood seizures was first observed by Klein and ... seizures, and normalization of the EEG in three of three children with Landau-Kleffner syndrome (74) Four children with Landau-Kleffner syndrome received early and prolonged ACTH or corticosteroid therapy, ... aphasia and improvement of seizure control Three to six years after discontinuation of hormone therapy the children were off medication and free from seizures and language disability Sinclair and...
Ngày tải lên: 12/08/2014, 05:21
Pediatric Epilepsy Diagnosis and Therapy - part 9 pptx
... (2.3%) had to discontinue ZNS therapy (sleeplessness and increased seizures, failure to gain weight, and behavioral changes in one patient each) Add-on Polytherapy Kim and colleagues have reported ... Biotransformation, Pharmacokinetics, and Interactions in Humans Absorption is rapid and complete and occurs in the gastrointestinal tract Bioavailability is good and similar in the fed and fasted states 30–40% ... trials and practice experience in Japan, subsequently published in either Japanese or English, and reviewed by Glauser and Pellock (53) In this detailed meta-analysis examining efficacy and safety...
Ngày tải lên: 12/08/2014, 05:21
Pediatric Epilepsy Diagnosis and Therapy - part 10 pdf
... with VNS therapy are generally transient and mild, and are often related to the duration and intensity of stimulation Serious adverse events have not been reported with standard therapy, and no ... United States The VNS therapy system consists of the implantable pulse generator and bipolar VNS therapy lead, a programming wand with software, a tunneling tool, and a hand-held magnet The original ... tamper- 64 • VAGUS NERVE STIMULATION THERAPY IN PEDIATRIC PATIENTS: USE AND EFFECTIVENESS 815 FIGURE 64-5 Intraoperative use of the handheld computer and programming wand to initiate stimulation ing...
Ngày tải lên: 12/08/2014, 05:21
Báo cáo y học: "Prevalence of Overactive Bladder, its Under-Diagnosis, and Risk Factors in a Male Urologic Veterans Population"
... Xu B and Song J Prevalence and risk factors of overactive bladder syndrome in Fuzhou Chinese women Neurourol Urodyn 2006; 25:717 Teleman PM, Lidfeldt J, Nerbrand C, Samsioe G, Mattiasson A and ... there was a statistically significant association between OAB and hepatitis (p=0.03, OR=2.2) See Table Table Prevalence of OAB, LUTS and OAB subtypes DISCUSSION The prevalence of OAB in men has ... urinary symptoms (OAB, LUTS and/ or BPH) Furthermore, those with OAB had a worse quality of life score Mean quality of life score for those with OAB was 3.4 of 6, and those without OAB 1.6 Thus,...
Ngày tải lên: 25/10/2012, 11:35
Tài liệu Cognitive Impairment in the Elderly – Recognition, Diagnosis and Management docx
... the Elderly – ecognition, Diagnosis and Management R Revised January 30, 2008 Recommendation Diagnosis When delirium and depression have been treated and/ or ruled out and cognitive impairment ... understand their present condition and prognosis, and have they been able to participate in the development of goals and realistic expectations for treatment? • Is the patient a suitable candidate ... left handed Take a piece of paper, hold it up in front of the person and say: Take this paper in your right/left hand (whichever is non-dominant), fold the paper in half once with both hands and...
Ngày tải lên: 13/02/2014, 18:20
Tài liệu Diagnosis and management of head and neck cancer docx
... acute radiotherapy and chemotherapy toxicity 26 1++ TREATMENT: CHEMOTHERAPY IN COMBINATION WITH SURGERY OR RADIOTHERAPY 8.2 Cetuximab in addition to radical radiotherapy A multicentre randomised ... definitive radiotherapy (with or without chemotherapy) and the neck with adjuvant radiotherapy (with or without chemotherapy) Radiotherapy delivered postoperatively to the primary site and/ or neck ... by radiotherapy or chemoradiotherapy alone.196,198 N2 and N3 disease is better treated by a combination of surgery and chemoradiotherapy (or radiotherapy in those unable to tolerate chemotherapy)...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Burns Regenerative Medicine and Therapy pdf
... excision and skin grafting therapy , and (2) ‘conservative repairing therapy (burns regenerative 16 Burns Regenerative Medicine and Therapy medicine and therapy) ’ The former is symbolized by the therapy ... Burns Regenerative Medicine and Therapy 31 32 Burns Regenerative Medicine and Therapy Case 2: Burns Regenerative Medicine and Therapy (BRT with MEBT/MEBO) Procedure and Results (fig 8, 9) First ... repair tissues and regenerate organs in vivo and in situ The mapping process of regeneration and duplication of human tissues and organs in vivo and in situ represents a general and typical process...
Ngày tải lên: 17/02/2014, 14:20
Tài liệu Báo cáo Y học: Receptor crosstalk Implications for cardiovascular function, disease and therapy ppt
... chloride (Cl–), sodium (Na+), K+ and Ca2+ channels, as they regulate the membrane potential and transportation of ions and substrates, controlling excitation and excitation-contraction coupling ... proteins, the Gs, Gi and Gq/11 to stimulate cardiac-specific ACII and ACV or PLC isoforms, utilizing cAMP-dependent PKA, PKC-a and PKC-f to activate a small subset of downstream effectors and ion channels ... the a1-AR and b-AR [10], b1-AR and OPRs [29] as well as the AT1R and ANP systems [32], although a Gi-mediated crosstalk bypassing PLC stimulation has also been proposed between b-AR and OPRs [30]...
Ngày tải lên: 21/02/2014, 15:20
PARKINSON''''S DISEASE AND MOVEMENT DISORDERS: DIAGNOSIS AND TREATMENT GUIDELINES FOR THE PRACTICING PHYSICIAN potx
... Y WU AND JONATHAN ISRAEL, 1998 The Pain Management Handbook: A Concise Guide to Diagnosis and Treatment, edited by M ERIC GERSHWIN AND MAURICE E HAMILTON, 1998 Sleep Disorders: Diagnosis and Treatment, ... PARKINSON'S DISEASE AND MOVEMENT DISORDERS: DIAGNOSIS AND TREATMENT GUIDELINES FOR THE PRACTICING PHYSICIAN CURRENT CLINICAL PRACTICE Parkinson’s Disease and Movement Disorders: Diagnosis and Treatment ... edited by J STEVEN POCETA AND MERRILL M MITLER, 1998 Allergic Diseases: Diagnosis and Treatment, edited by PHIL LIEBERMAN AND JOHN A ANDERSON, 1997 Osteoporosis: Diagnostic and Therapeutic Principles,...
Ngày tải lên: 05/03/2014, 23:20
Neuromuscular Junction Disorders Diagnosis and Treatment ppt
... Revisled and Expanded, edited by William C Koller 14 Handbook of Pediatric Epilepsy, edited by Jerome V Murphy and fereydoun Dehkharghani 15 Handbook of Tourette's Syndrome and Related Tic and Behavioral ... Sidhu, Marc Laruelle, and Philippe Vernier 57 Handbook of Olfaction and Gustation: Second Edition, Revised and Expanded, edited by Richard L Doty 58 Handbook of Stereotactic and Functional Neurosurgery, ... 33 Handbook of Neurological Speech and Language Disorders, edited by Howard S Kirshner 34 Therapy of Parkinson's Disease: Second Edition, Revised and Expanded, edited by William C Koller and...
Ngày tải lên: 05/03/2014, 23:20
Guidelines on the diagnosis and management of acute pulmonary embolism pot
... history, and the pathophysiology of PE have been described more extensively elsewhere.2 – This document focuses on currently available and validated methods of diagnosis, prognostic evaluation and therapy ... respiratory failure, and congenital or acquired thrombophilia, hormone replacement therapy and oral contraceptive therapy The incidence of VTE increases exponentially with age and this is the case ... HR, Prandoni P Undiagnosed malignancy in patients with deep vein thrombosis: incidence, risk indicators, and diagnosis Cancer 1998;83:180 –185 343 Monreal M, Fernandez-Llamazares J, Perandreu...
Ngày tải lên: 08/03/2014, 14:20
Diagnosis and management of chronic kidney disease docx
... occupational therapy b) dietetics c) physiotherapy d) psychological and social support 43 Diagnosis and management of chronic kidney disease Annex Expressions of urinary protein concentration and their ... National Institute for Health and Clinical Excellence (NICE) in England and Wales The Scottish Medicines Consortium (SMC) provides advice to NHS Boards and their Area Drug and Therapeutics Committees ... Potassium and renal function should be checked after commencing and changing the dose of angiotensin converting enzyme inhibitors and/ or angiotensin receptor blockers 19 Diagnosis and management...
Ngày tải lên: 08/03/2014, 14:20
GESTATIONAL DIABETES CAUSES, DIAGNOSIS AND TREATMENT pot
... GDM about the condition and its management, so that they can acquire a clear understanding of the characteristics and demands be emphasized on the importance of exercise and diet control importance ... for the mother and foetus and to avoid excess weight gain and postprandial hyper‐ glycemia Calculation of daily caloric intake is based on body weight, age, physical activities and gestational ... Insulin therapy Once diagnosis is made, nutrition therapy is advised If it fails oral antidiabetic agents can be tried If oral agents failed to acheive FPG of ≤ 5.0 mmol/L and 2-h postprandial...
Ngày tải lên: 08/03/2014, 19:20
Lung cancer - The diagnosis and treatment of lung cancer pdf
... radiotherapy Preoperative chemotherapy and surgery Surgery followed by chemotherapy Surgery then chemo- and radiotherapy Radical radiotherapy Chemotherapy and radical radiotherapy b a Chemotherapy ... England, for patients diagnosed between 1993 and 1995 and followed up to 2000, 21.4% of men and 21.8% of women with lung cancer were alive year after diagnosis and only 5.5% of both men and women ... information, both verbal and written, on all aspects of their diagnosis, treatment and care This information should be tailored to the individual requirements of the patient, and audio and videotaped formats...
Ngày tải lên: 15/03/2014, 00:20