endogamy consanguinity and genetic disease in arab populations

... months and, in September 1979, was even low as half a dozen flies ; afterwards, in a few weeks, it increased rapidly in number and became stabilized Concerning the Bonlez strain 40 inseminated ... In January 1979 three times 60 pairs of flies of the Oregon strain were placed in population cages at 21°, 25° and 29 °C, respectively The 2 1and 25 °C populations expanded rapidly in number and ... reconditioning of the gene pool of the new colony resulting in a genetic revolution More or less in the same line of thinking ARSON C (1971) believes that « when population derived from a single founder...

Ngày tải lên: 09/08/2014, 22:23

... juvenile Quercus populations but not the succeeding life stages The genetic multiplicity was very large in all samples investigated including single-population samples This finding concurs with ... above average The samples which originated from seed collections in single populations (no and 5, and 8, and 10) tended to be more differentiated than the remaining samples which descend from population ... the origin of the studied samples, see Müller-Starck and Ziehe (1991) Genotyping proceed Genetic control and inheritance of isoenzymes verified beforehand by utilizing full-sib families and their...

Ngày tải lên: 08/08/2014, 19:21

... harbor introduced mouflon populations (Nadler et al, 1971; ONC, 1985) In France, introductions took place in the years 1950-1965 and wild-living populations are now present in the mountains of ... captive and wild-living) by blood typing and by electrophoresis of transferrin and hemoglobin The aim of this study was to determine the effects of founder events variability of introduced mouflon populations ... hemoglobin and transferrin loci in the populations Four alleles were detected at the transferrin locus, TrfD being the most common, as in other mouflon populations (Nadler et al, 1971; Stratil and...

Ngày tải lên: 09/08/2014, 18:21

... markers depends on the inbreeding In the less inbred LD and the genetic distance in livestock 287 Figure Mean inbreeding coefficient across generations in the four simulated populations From top ... model (indicated by the determination coefficient, r2 ) depends on the inbreeding: r2 decreases when the inbreeding coefficient increases (Tab III) In the less inbred populations (pop100 and pop25 ... can provide more insight in our understanding of sources of LD by comparing for example populations or chromosomes Since there is an increasing interest in the use of single nucleotide polymorphisms...

Ngày tải lên: 14/08/2014, 13:22

... Enrollment of cases in hospital, clinical examination and recording, data interpretation and manuscript preparation; BD: Field investigation, Clinical examination and recording, data interpretation, ... showing INDIAN PEDIATRICS JUNE 10, 2012 [E-PUB AHEAD OF PRINT] KAR, et al HAND, FOOT AND MOUTH DISEASE eosinophilia and two cases with neutrophilia Routine and microscopic examination of stool and ... subjects for investigation Routine blood examinations including complete blood count, Erythrocyte sedimentation rate, urine routine and microscopy and stool routine and microscopy were done in all...

Ngày tải lên: 05/03/2014, 12:20

... Total: 240360 Sway during standing, varying vision and base of support & weightshifting during standing BBS, activity level Continuous visual feedback of COP vs Tai Chi chuan training vs Educational ... clear indications regarding the long-term additional benefit of applying biofeedback in interventions for balance and mobility training in older populations In addition, it is difficult to determine ... [52] after the intervention In out of studies, a significant decrease in reaction time during quiet standing in favor of the training group was demonstrated In addition, significant and small-to-moderate...

Ngày tải lên: 19/06/2014, 08:20

... before the beginning of the two rainy periods, e.g in June and September Those vaccinations should, in our opinion, be in addition to the already individually performed vaccinations of single animals, ... of the disease and thereby indicating the best time points of administering the vaccine Thus, individually vaccination is already performed on the large ruminant population, but with vaccines of ... 35 and for C >= 35 both produce subclinical disease [12,17] During our study we have seen only a sporadic occurrence of animals with clinical signs of FMD, mainly in April 2006 and mainly in...

Ngày tải lên: 20/06/2014, 01:20

... used in forest management In the Iberian Peninsula cork oak is mainly used for manufacture of bottle stoppers, which is indispensable to the wine industry In Spain, the total cork production in ... selected elite-trees in the development of breeding programs, and the usefulness of SSR and ISSR markers in breeding experiments and to establish of DNA-fingerprinting of cork oak trees Finally, net outcome ... locus to 0.324 in QpZAG15 locus Considering all the three loci combined there are about one chance in 000 that two individuals selected randomly from a sample possessing the allele and the genotype...

Ngày tải lên: 07/08/2014, 16:21

... dépérissement INTRODUCTION populations and among populations in the natural range of species in order to adapt Oak trees are dominant forest tree species in Germany and an important ecological and economical ... conservation and forest tree breeding, it is important to gain information about the genetic structure effect on the sensitivity to ’European oak decline’ and the influences of decline on genetic ... L In: Genetic Effects of Air Pollutants in Forest Tree Populations (F Scholz, HR Gregorius, D Rudin, eds), Springer-Verlag, Berlin, 127-142 Müller-Starck G, Ziehe M (1991) Genetic variation in...

Ngày tải lên: 08/08/2014, 18:21

... with in most cases an adaptive interpretation [27] For quantitative traits, investigations on natural populations have mainly demonstrated spatial genetic variations such as latitudinal clines in ... calculate the co-ordinates of a maximum, minimum or inflexion point, for wing and thorax length, Vg and CTl9 or wing/thorax ratio, respectively RESULTS 3.1 Larval density and size variation Figure1 ... 17, 21, 25, 28 and 31 °C) From each line at each temperature, ten females and ten males were randomly taken and measured for two quantitative traits (wing and thorax length) with a binocular microscope...

Ngày tải lên: 09/08/2014, 18:21

... age Matings were mainly performed using artificial insemination (AI) Females were inseminated twice at a 12-h interval before 1992 and three times at a 12-h interval between successive AI since ... composite line and selecting it for growth and carcass traits [1, 5] In collaboration with INRA, the Pen Ar Lan breeding company has undertaken since 1983 the constitution and selection of a Chinese ... production and reproduction traits in the Tiameslan line MATERIAL AND METHODS Creation, management and selection of the Tiameslan line Two similar sublines were created in 1983 and 1985 in the nucleus...

Ngày tải lên: 09/08/2014, 18:21

... estimate genetic trends in the Tiameslan line after 12 years of selection Genetic trends in a Chinese × European pig line II 59 MATERIAL AND METHODS The Tiameslan line was created in 1983 by mating ... NW and SURV included parity and farrowing batch as fixed effects, the additive genetic value and the permanent environment of the sow as random effects, as well as age within parity and sow and/ or ... obtained for W22w and DT, particularly in males (Figs 1c and 1d) Yearly phenotypic and genetic trends were, respectively, 0.72 and 0.90 kg for W22w, – 1.18 and – 0.54 days for DT in males and...

Ngày tải lên: 09/08/2014, 18:21

... seemed interesting to compare Indian populations living under tropical and subtropical climates, to temperate populations (France) experiencing mild summers and cold winters As shown in figure ... and also in the sibling species D simulans (Capy et al, 1988) In D melanogaster, a latitudinal cline was observed between latitudes of 30° and above, and this cline was confirmed in populations ... same in French and Indian populations A precise comparison of the shape of the reaction norms remains to be undertaken In Indian populations, thoracic pigmentation increases also with altitude In...

Ngày tải lên: 09/08/2014, 18:22

... an infinite number of independent loci, with identical and small effects It will then be called in the following ’infinitesimal model’ or IM The computation of the inbreeding coefficient in this ... mates and inbreeding induced in the offspring and of the changing variance of gene effects due to genetic drift and faster or slower fixation of alleles The need of unknown parameters to introduce ... experiments on maize [5] expressed genetic progress over 76 generations, suggesting that genetic variability is infinite according to the infinitesimal theory In animal breeding also, selection experiments...

Ngày tải lên: 09/08/2014, 18:22

... HET and PHP individuals were similar in type to those carried out in other works dealing with individuals taken from natural populations In both cases the individuals were classified according ... thousands expected to be polymorphic In recent papers different possible mechanisms are suggested K & OBLIANSKY IVSHITS L (1983), in human populations, and L et al EDING EARY (1983), in pitch pine, ... effect and genetic variability in ARUYAMA HAKRABORTY populations Evolution, 29, 1-10 PIERCE B.A., M J.B., 1982 Allozymic heterozygosity and growth in the tiger salamander, ON TT I Ambystoma tigrinum...

Ngày tải lên: 09/08/2014, 22:22

... principle of these experiments was to divide a population of a given origin into certain number of subpopulations and then submit them to different environments After a certain time these subpopulations ... wild laboratory strain Oregon-R That strain was maintained in our laboratory at 25 °C for at least 15 years by transferring a hundred flies every third week into fresh half-pint milk bottles The ... Oregon-R strain started by putting groups of 120 flies in population cages at 21°, 25° and 29 °C, respectively The number of flies in the 21° and 25 °C subpopulations grew rapidly and eventually...

Ngày tải lên: 09/08/2014, 22:22

... severe proteinuria and hematuria Her erythrocytes were dysmorphic, and there were some cylinders present (hyaline and granulated) Proteinuria of 6.76 g/ 24 h and albuminuria of 3112.4 μg/min were ... yersiniosis, leptospirosis, Chlamydia, and different viral infections The pathophysiology seems almost the same in all of these infections, including Legionnaires’ disease [4,6] In our case, interstitial ... Legionella organism in the histological and ultrastructural examination, but the patient history and clinical findings implied a direct bacterial involvement in the pathogenesis of the disease The elevation...

Ngày tải lên: 10/08/2014, 23:21

... patients[35] Inflammation caused by IL6 and TNFα whilst modulating a response to TB infection could cause an increase in insulin resistance thus decreasing insulin production causing an increase in blood ... since 1950 Searches were undertaken in MEDLINE and EMBASE, plus screening of reference lists in identified articles Potentially relevant reports, bulletins and guidelines were also screened, including ... examples of chronic and infectious disease Competing interests The authors declare that they have no competing interests, that there are no conflicts of interest and/ or financial disclosures...

Ngày tải lên: 11/08/2014, 14:21

... metabolic syndrome and insulin resistance, and this correlates with increases in homocysteine and high sensitivity CRP [94] Treatment of insulin-resistant states may improve CVD profiles in SLE Our group ... plaqueresiding CD4+ T cells to increase TNF-related apoptosisinducing ligand (TRAIL) expression, which results in killing of plaque stabilizing cells and a potential increase in the risk of plaque rupture ... recognizing epitopes of various molecules, including oxidized LDL, and by secreting IFN-γ, which then leads to increased in ammatory cytokine production This chronic production of in ammatory cytokines...

Ngày tải lên: 12/08/2014, 15:22

... analysis, and helped to draft the manuscript RPM participated in genotyping and data analysis TRV, JAMF and LR participated in the acquisition and interpretation of data BF was involved in the acquisition ... reduction in plaque formation and macrophages, Th1 and smooth muscle cell accumulation, and increased expression of anti-inflammatory cytokines such as IL-10 [4,30,31] Furthermore, studies using an ... in the acquisition and interpretation of data and in revising it critically for important intellectual content JM and MAGG made substantial contributions to the conception and design of the study,...

Ngày tải lên: 12/08/2014, 17:22