electronic searching for clinical trials information

... closed square) for six consecutive days A 0.9% NaCl-treated control group (n = 6, hatched square) was also included for comparison (A) Tumor volume is presented normalized to its volume before initiation ... Gottlieb E: Targeting metabolic transformation for cancer therapy Nat Rev Cancer 2010, 10:267-277 Pelicano H, Martin DS, Xu RH, Huang P: Glycolysis inhibition for anticancer treatment Oncogene 2006, ... lysates were clarified by centrifugation at 11000 × g for 15 Resulting supernatants were fractionated on SDS-PAGE and transferred onto PVDF membranes for immunoblot analysis (InmobilonP, Millipore)...

Ngày tải lên: 18/06/2014, 19:20

... closed square) for six consecutive days A 0.9% NaCl-treated control group (n = 6, hatched square) was also included for comparison (A) Tumor volume is presented normalized to its volume before initiation ... Gottlieb E: Targeting metabolic transformation for cancer therapy Nat Rev Cancer 2010, 10:267-277 Pelicano H, Martin DS, Xu RH, Huang P: Glycolysis inhibition for anticancer treatment Oncogene 2006, ... lysates were clarified by centrifugation at 11000 × g for 15 Resulting supernatants were fractionated on SDS-PAGE and transferred onto PVDF membranes for immunoblot analysis (InmobilonP, Millipore)...

Ngày tải lên: 20/06/2014, 03:20

... protocols for the treatment of PDB with oral bisphosphonates is 40 mg/day of alendronate for six months and 30 mg/day of risedronate for two months [1,6] About six years ago, we started treatment for ... effective than etidronate for the treatment of PDB [11], and (c) alendronate seemed to be more suitable for the treatment of Japanese patients since the dose of alendronate used for the treatment of ... of alendronate for one year after the cessation of treatment [9] Furthermore, in this study, we have shown that the administration of low-dose alendronate for six months has afforded an effective...

Ngày tải lên: 11/08/2014, 12:20

... excluded from the study For outpatients, we extracted the following information from the outpatient database of the cohorts: demographic characteristics; date of starting treatment; clinical stage upon ... inpatient service records for all 58 HIV patients who had been admitted to AMH during 2004/5 because the HIV Clinic database did not contain information regarding inpatient clinical events and service ... AIDS for all inpatients services and for all outpatients not receiving ART Except for the costs of outpatient services to those receiving ART, both the outpatient and inpatient costs are higher for...

Ngày tải lên: 13/08/2014, 11:22

... return for clinical examination, SPT and serological tests, regardless of status of completion of IT Many patients also met for an extra consultation at a later date for the same procedures Information ... Fisher's exact test For the duration of IT two samples t-test was used Page of (page number not for citation purposes) Clinical and Molecular Allergy 2005, 3:12 http://www.clinicalmolecularallergy.com/content/3/1/12 ... This study was started in 1980 and was ongoing for many years However the main author has been in charge during the whole period The clinical information and laboratory data have been continuously...

Ngày tải lên: 13/08/2014, 13:22

... subcutaneously for hydration and were placed in temperature controlled housing overnight for monitoring recovery All surgical and animal handling procedures were performed as approved under the Guide for ... provide impetus for making the good experiment “great” Lastly, I thank my research advisory committee for steering me towards the more important goals in graduate research training and for all the ... cytosol, resulting in the formation of the apoptosome Apoptosomes are responsible for activating caspases, including the well-known catalytic enzyme caspase 3, that are responsible for promoting apoptotic...

Ngày tải lên: 24/08/2014, 09:14

... from the action of proteases, therefore leaving intact some regions of the protein that may be relevant to its allergenic properties The BLG conformers transiently formed during a physical treatment ... may have practical relevance as for decreasing the immunoreactivity of the protein Therefore, we also tested some of the hydrolysis products obtained in this study for their immunoreactivity towards ... in the enzyme assays performed on the heated BLG/protease mixtures competed with the artificial substrates for binding to the enzymes In our conditions, the assay mixtures for residual protease...

Ngày tải lên: 21/02/2014, 15:20

... does not necessarily provide information on what specific dental condition was related to the impact Condition-specific OHRQoL measures attempt to provide such information by attributing oral ... adolescents with and without normative need for orthodontic treatment, better results were found for CS-OIDP attributed to malocclusion than for OHIP-14 Effect size for CSOIDP attributed to malocclusion ... additional information for oral health needs assessment when the specific link between a specific oral condition leading to impacts on quality of life is required to prioritise need for professional...

Ngày tải lên: 18/06/2014, 19:20

... qualify for being tested according to the Dutch Medical Research Involving Human Subjects Act of 1999 [16] Patients signed an informed consent form before any study related procedure was performed ... were about points more advantageous for completers than for non-completers Mean changes were close to zero or slightly negative for noncompleters, while results for completers were even slightly ... expected benefits against risks patients need quantified information on effectiveness before deciding to start DMD treatment Randomized controlled trials (RCTs) investigate efficacy and mostly not include...

Ngày tải lên: 20/06/2014, 15:20

... results Clinical trials, including the present one, typically involve a number of inclusion and exclusion criteria, and it is therefore not possible to extend findings from clinical trials to ... http://www.annals-general-psychiatry.com/content/9/1/10 weeks Target fluoxetine dosages were 10 mg/day for the first week, 20 mg/day for weeks to 4, 40 mg/day for weeks to 8, and 60 mg/day for weeks to 12 The dose was increased to meet the target ... months after randomization) were 35.2% for the fluoxetine group and 61.8% for the placebo group; after year, they were 45.9% for the fluoxetine group and 72.0% for the placebo group Mean (SD) residual...

Ngày tải lên: 08/08/2014, 23:21

... intervals shortened in case of insufficient clinical response to treatment Clinical evaluations and blood sample collection were performed directly before infusions All adverse events, including ... immunomodulating agents before the initiation of infliximab treatment for development of infusion reactions during infliximab treatment in patients with chronic arthritis treated clinically Materials ... Positive patients predictive value for combination of baseline ANA status and methotrexate treatment for development of infusion reactions in RA methotrexate treatment for development of infusion reactions...

Ngày tải lên: 09/08/2014, 08:22

... (BMI) before randomization; therefore, most appetite increase probably occurred before the study started, especially when considering that all patients had been receiving olanzapine for to 54 ... monitoring is performed, appetite does not add additional information predicting future weight changes during treatment with olanzapine: early weight change may be a more useful predictor for longterm ... investigator as appropriate for the individual patient for months (Table 1) [17] Detailed inclusion and exclusion criteria can be found in the primary study reports [16-19] Clinical assessment of...

Ngày tải lên: 11/08/2014, 16:22

... controlled trials designed to compare antipsychotic differences among ethnic groups The majority of schizophrenia patients enrolled in clinical trials is of white descent and separate results for ethnic ... olanzapine for the black patient group was 15.5 mg (SD = 4.3) and was 15.3 mg (SD = 4.2) for the white patient group The median exposure was 164 days for black patients and 166 days for white ... difference was not clinically significant to warrant a statistical adjustment For the efficacy endpoints, we choose only a selected few measures that we felt were clinically significant For the safety...

Ngày tải lên: 11/08/2014, 16:22

... CD127 on CD8 memory T cells The analysis was performed on 20 CHB patients treated with telbivudine at 0, 24 and 48 weeks Statistical analyses were performed among well responders (black bar), 10 ... cells is specific for cleared virus [e.g influenza virus, respiratory syncytial virus (RSV) and acute HBV infection] while low CD127 expression on human CD8 T cells is specific for persisting virus ... China to W J Ma Authors’ contributions LGC and YLJ performed the majority of experiments and contributed equally to this work MWJ did most of clinical works JX and ZL provided analytical tools and...

Ngày tải lên: 12/08/2014, 01:21

... The European Community is not liable for any use that may be made of the information herein We thank ServiceXS for performing the real-time PCR experiments using Dynamic Array on the BioMark™ ... preparation and microarray hybridization were performed as described previously [13,19] Data storage and filtering were performed using the Stanford Microarray Database [20,21] as described previously ... genes was selected for validation analysis using a BioMark™ Real-Time PCR [Polymerase Chain Reaction] System (Fluidigm Corporation, South San Francisco, CA, USA) Detailed information of the gene...

Ngày tải lên: 12/08/2014, 11:22

... reporting a sudden headache accompanied by nausea and vomiting for ten days The patient had a history of hypertension for years and diabetes for 10 years, which were well-controlled with antihypertensive ... inferior cerebellar arteries 9,11,12 For such aneurysms combined aggressive treatment should be performed, but is more difficult In these cases, one used clipping for the basilar artery aneurysm and ... The clinical data is summarized in Table The following is a summary of the studies Table Clinical data for all cases in this study Case Study Kumagai et 1981 al Matsuzawa 1982 et al 54/F aortitis...

Ngày tải lên: 25/10/2012, 11:04

Ngày tải lên: 13/02/2014, 12:20

... the analysis was performed after transfection Therefore, all the following analyses were performed days after transfection At that time point, the size of the inclusions formed by either httEx1-72Q-EGFP ... pathology of NO• results from its reaction with O2•– to form peroxynitrite (ONOO•–), which can diffuse for several micrometers before decomposing to form the powerful and cytotoxic oxidants OH• and ... disruption induced by httEx1-polyQ or FCCP For electron microscope analysis, transfected COS-7 cells were grown for 48 h in 60 mm diameter plates before being fixed for 30 at °C in a buffer composed of...

Ngày tải lên: 19/02/2014, 06:20

... against any pandemic virus and for the early detection of treatment and prophylaxis failures, which may be an indication of the emergence of resistance For further information, please see the more ... drugs, antivirals can have side effects for some people To date, severe side effects are unusual for neuraminidase inhibitors and even less common than for M2 inhibitors However, minor side effects ... This also highlights the importance of not relying on any single antiviral and therefore the constant need for public support, investment and development of new therapies Considerations should...

Ngày tải lên: 05/03/2014, 22:21