efficacy and safety of commonly used modalities

... Hypnotics and sedatives were used by 25% of aripiprazole patients and 21% of placebo patients At least adverse event was reported by 142 (76%) of the 186 patients in the placebo group and 154 (87%) of ... sedatives were used by 24% of aripiprazole patients and 17% of placebo patients At least adverse event was reported by 132 (72.9%) of the 181 patients in the placebo group and 155 (85.2%) of the 182 ... the role of the 5-HT-mediated systems in the mechanism of action of aripiprazole [33] Aripiprazole reaches peak concentration (Cmax) to h after ingestion, and has a bioavailability of 87% and half...

Ngày tải lên: 08/08/2014, 23:21

... double-blind and placebo-controlled clinical study, we sought to evaluate the efficacy and safety of 5-Loxin® in treatment of OA of the knee We assessed the effectiveness of 100 mg/day and 250 mg/ ... Haematological and biochemical evaluations For assessment of safety of 5-Loxin®, several parameters were evaluated in serum, urine and whole blood of all patients at each visit of the study duration ... analyses using SAS software to evaluate the efficacy of two doses of 5-Loxin® in comparison with the placebo group in terms of improvement in pain and physical ability scores, and to assess biomolecular...

Ngày tải lên: 09/08/2014, 10:23

... Analysis of days of onset of common cold symptoms Shown are the numbers of patients for verum, placebo and total divided into groups with days of onset of common cold symptoms at the point of inclusion ... patient 23 reported migraine and puffy eye lids, used ibuprofen and anti-histamine as concomitant medication and was therefore excluded from the efficacy analysis of symptoms One Iota-Carrageenan ... protocol Subject 11 reported vomiting, nausea and abdominal pain presumably caused by an infection of the gastrointestinal tract and furthermore used ibuprofen as concomitant medication Subject 23...

Ngày tải lên: 12/08/2014, 11:22

... (breathlessness on a scale of to 4; cough, sputum production and wheezing on a scale of to 3), use of daily rescue medication and concomitant medication were recorded in the patient’s diary and reviewed by ... using an analysis of covariance (ANCOVA) model with treatment and sex as factors, and baseline values and age as covariates; the same model, without adjustment for age and sex, was used to analyse ... in favour of aclidinium for cough and sputum production (Week 1), breathlessness (Week 12), wheezing (Week 28) and use of daily rescue medication (Weeks 12 and 28) (p < 0.05 for all) Safety The...

Ngày tải lên: 12/08/2014, 13:22

... (maximum change of 57.0 mm) and 3.5 mm (-1.0, 20.0) with placebo (maximum change of 61.0 mm) Safety Adverse events were reported in 51.0% of patients treated with tiotropium, and 61.5% of patients ... all tiotropium studies [11-14] and supports the clinical relevance of the sustained efficacy of tiotropium and reduction of COPD exacerbations The actual magnitude of the reduction in rescue medication ... Pedersen OF, Peslin R, Yernault JC: Lung volumes and forced ventilatory flows Work Group on Standardization of Respiratory Function Tests European Community for Coal and Steel Official position of...

Ngày tải lên: 12/08/2014, 15:20

... the methods of implementation and technical characteristics of the ventilation devices (Table 3) and regarding the definition and adequacy of criteria for ETI (Table 3) The analysis of safety issues ... practice and more challenging for clinicians to understand The aim of our study was to systematically review the evidence in order to answer key clinical questions about the efficacy and safety of ... analyze the impact of patients' baseline hypercapnia on the efficacy of CPAP and NPPV and to test a common clinical hypothesis about the advantage of NPPV when using higher levels of pressure support...

Ngày tải lên: 12/08/2014, 23:23

... experiments and data acquisition MV conducted experiments, interpretation of data, and manuscript drafting GB performed study conception and design, statistical analysis and interpretation of data, and ... Care Vol 10 No Livigni et al A variety of recent studies have investigated the efficacy and safety of pumpless arterovenous devices to remove CO2 [1417], which offer several advantages over ECMO: ... cannulation, increase of left-to-right shunt (thus excluding patients with cardiac failure), and no direct blood flow control Our study was designed to evaluate the efficacy and safety of a veno-venous...

Ngày tải lên: 13/08/2014, 03:20

... pharmacology of drugs, a safety system in standard treatment would help to solve the black box of safety and of unknown relationship between the dosage and actions of drugs (e.g effectiveness and side ... including both standardized measurements of blood concentrations of psychotropic drugs and the documentation of efficacy and side effects of the medication For practical reasons, the use of an internet ... situation of lower standards of drug -safety for children continues, due the lack of paediatric pharmacokinetic and -dynamic trials and nonexisting data The European Agency for the Evaluation of Medicinal...

Ngày tải lên: 13/08/2014, 18:21

... PRESS INC Efficacy and Safety of Pregabalin in GAD Figure Efficacy of Pregabalin as Measured by Unadjusted Mean HAM-A Total Score by Week and Treatment Group Versus Placebo (analysis of covariance)a,b,c ... Hospital Anxiety and Depression Scale48 (patient rated) consisting of the anxiety subscale (HADS-A) and the depression subscale (HADS-D) Safety and Tolerability Analyses Safety and tolerability ... efficacy variable of the study) were compared between each dose of pregabalin and placebo, as well as between venlafaxine and placebo and (in post hoc analyses) between each pregabalin dose and...

Ngày tải lên: 21/08/2016, 18:51

... actuarial rate of HC and HN were 62,4% and 37,6%, respectively, and the 5-year actuarial rate were 81,2% and 55,4%, respectively (Figures and 2) Table Distribution of results of radiological ... we used the dosage of ACTH serum as a parameter In GH-secreting, we evaluated the basal GH and IGF-1 and appropriate sex and age, in prolactinomas, we consider the level of serum prolactin and ... pre and post-radiosurgical GH and IGF-1 levels were, respectively, 5.8 and 2.9 ng/ml and 688.5 and 361.5 ng/ ml; the median pre- and post-radiosurgircal prolactin levels were, respectively, 55 and...

Ngày tải lên: 09/08/2014, 09:20

... suffered in 20% of cases of paroxysmal, in 37% of persistent, and in 41% of cases of long standing persistent AF There was no statistical significant correlation in between type of AF and diagnosis ... without the need of large thermal gradients and without jeopardizing adjacent structures (Figure 1) [6] The purpose of this study was to evaluate the efficacy of left atrial HIFU ablation of AF with ... Diagnosis and classification of AF were established by standard ECG and holter ECG in all patients prior to admission AF was defined paroxysmal in 29%, persistent in 31% and long standing persistent...

Ngày tải lên: 10/08/2014, 09:22

... all-cause time to discontinuation and PANSS Total score between white, black, and Hispanic subgroups Another study looked at the impact of race on the efficacy and safety of long-acting risperidone ... the analysis, we Page 10 of 11 used MMRM analysis for efficacy (PANNS and CGI-S) and weight Last observation carried forward was used to analyze lipids, glucose, EPS, and weight MMRM could not ... Ciliberto N, Bossie CA, Urioste R, Lasser RA: Lack of impact of race on the efficacy and safety of long-acting risperidone versus placebo in patients Page 11 of 11 27 28 29 30 31 32 33 34 35 36 37 38...

Ngày tải lên: 11/08/2014, 16:22

... comparative efficacy and tolerability of 5-Loxin® and Aflapin® in the treatment of OA of the knee Materials and Methods Study materials BE-30 (5-Loxin) is a novel Boswellia serrata extract standardized ... Hematological and biochemical evaluations For assessment of safety of 5-Loxin® and Aflaseveral parameters were evaluated in serum, urine and whole blood of all subjects at each visit of the study ... software to evaluate the efficacy of 5-Loxin® and Aflapin® in comparison with the placebo group in terms of improvement in pain and physical function scores at baseline and on days 7, 30, 60 and...

Ngày tải lên: 25/10/2012, 11:40

... Comparison of resveratrol content of Swiss wines from organic and integrated viticulture (1997 grape harvest).55 Dossier Quality and Safety of Organic Products Secondary metabolite content of organic and ... variety of direct parameters such as loss of water and substance, accumulation of harmful substances and microorganisms, and physiological parameters such as respiration, and enzymatic, defence and ... biodiversity and landscape, soil, water, climate and air, and also to energy consumption In short, organic is better for people, animals and the environment 22 Quality and Safety of Organic Products...

Ngày tải lên: 28/03/2014, 20:20

... http://www.jiasociety.org/content/9/4/7 Respectively, 47% and 53% of patients were at CDC stages B and C Seven of the patients at CDC stage C had a history of pulmonary tuberculosis, and had a history of extrapulmonary tuberculosis ... resourcelimited countries and is now used by hundred of thousands of patients worldwide However, d4T is no longer recommended in Western countries because of its longer-term toxicity profile that includes, ... 14:1601-1610 Abstract Gerstoft J, Kirk O, Obel N, et al.: Low efficacy and high frequency of adverse events in a randomized trial of the triple nucleoside regimen abacavir, stavudine and didanosine AIDS...

Ngày tải lên: 20/06/2014, 08:20

... However, there are no data on the effectiveness and safety of this combination We assessed virologic, immunologic, and clinical benefits and safety of this combination in HIV-infected Indian patients ... developed IRIS on TDF/FTC/EFV (8 cases of tuberculosis, of cytomegalovirus vitreitis, of hepatitis B virus, of Pneumocystis jiroveci pneumonia, of herpes zoster, and of cryptococcal meningitis) One ... treatment (because of failure or toxicity) was determined Median CD4 counts before and after initiation of the regimen were determined at and 12 months of follow-up Univariate analysis was used to determine...

Ngày tải lên: 20/06/2014, 08:20

... one aspect of EM efficacy Efficacy of EM for critical care and procedures Efficacy of EM for efficiency or cost of care Efficacy of EM for public health and preventive medicine Efficacy of EM for ... accuracy of reading films, etc.) Efficacy of EM for trauma and airway management Efficacy of EM for using ultrasound Efficacy of EM faculty Efficacy of EM residencies Overviews and editorials of EM efficacy ... efficacy or value of EM or aspects of EM delivered care Case reports and case series of successful clinical care in the Emergency Department (ED) were not included (there are of course thousands...

Ngày tải lên: 21/06/2014, 01:20

... depletion and were reversible within months of drug withdrawal The pharmacokinetic profile of one or two doses of belimumab was dose proportional and consistent with a fully human mAb A half-life of ... initiation of phase II studies investigating the safety and clinical activity of belimumab in patients with SLE and rheumatoid arthritis Competing interests JZ, WC, and WF were all employees of Human ... was used to examine the difference across all treatment groups, and the Wilcoxon test was used to compare the differences between placebo and each of the belimumab-treated groups An analysis of...

Ngày tải lên: 09/08/2014, 13:21

... information retrieval and sharing of ideas and content difficult Authors used only one-half of the terms identified in this study in their titles and abstracts of KT articles and of these, approximately ... foundations of KT They describe the theory, concepts, tools, or models of KT and delineate some of the issues and challenges of working in the area The following topics are examples of the sort of paper ... database and list of KT terms were developed independently The database and list were used in this study to determine which KT-related terms authors used in the titles and abstracts of articles and...

Ngày tải lên: 11/08/2014, 05:21