effects of some centrally acting drugs on caeruloplasmin

... centrifugation to the separation of the P fraction , G B ANSELL AND SHEILA SPANNER The zonal centrifugation of the P , fraction The technique of zonal centrifugation was developed by Anderson but ... SUMMARY The separation of the components of the myelin-free crude mitochondrial fraction of whole brain tissue in centrifuge tubes is compared with a separation by zonal centrifugation On a shallow, ... observations of Lenard and Singer (1968) on the red cell membrane and those of Condrea and Rosenberg (1968) and Rosenberg and Condrea (1968) on the squid giant axon From studies on the incorporation of...

Ngày tải lên: 29/03/2014, 13:20

... immunoreactivity of the a1-subunit of the Ó FEBS 2002 Palytoxin action on colonic H+/K+-ATPase (Eur J Biochem 269) 3909 Fig Immunohistochemical detection of the a1-subunit of the Na+/K+-ATPase in rat colonic ... membrane of colon epithelial cells Ouabain inhibition of the colonic H+/K+-ATPase has been a matter of controversy in many investigations Early experiments involving ATPase measurements on apical ... in the mucosal solution using a palytoxin concentration of 10)8 molÆL)1 For theoretical reasons it is not possible that administration of palytoxin to the basolateral side of an epithelium can...

Ngày tải lên: 17/03/2014, 11:20

... information is available on the effect of MDA-7 on prostate cancer cells Studies of adenoviral vectorinduced expression of MDA-7 in human prostate cancer cells demonstrated varying degree of inhibition ... Page of Figure Response to rhMDA-7 in cell adhesion (top) and migration (bottom) by CA-HPV-10 wild type cells, a cell with high levels of expression of TGase-4 Figure Effects of rhMDA-7 on the ... observations from the present study are interesting and have important clinical implications, e.g., therapeutic consideration of the use of MDA-7 would be dependent on the degree of expression of TGase-4...

Ngày tải lên: 18/06/2014, 19:20

... information is available on the effect of MDA-7 on prostate cancer cells Studies of adenoviral vectorinduced expression of MDA-7 in human prostate cancer cells demonstrated varying degree of inhibition ... Page of Figure Response to rhMDA-7 in cell adhesion (top) and migration (bottom) by CA-HPV-10 wild type cells, a cell with high levels of expression of TGase-4 Figure Effects of rhMDA-7 on the ... observations from the present study are interesting and have important clinical implications, e.g., therapeutic consideration of the use of MDA-7 would be dependent on the degree of expression of TGase-4...

Ngày tải lên: 20/06/2014, 03:20

... expression of membrane-bound CIP on vascular EC under hypoxic conditions may contribute to an anti-inflammatory action of statins in RA The combined effects of DAF, at the level of C3 and C5 convertases, ... of the hypoxic environment used was confirmed by the induction of HIF-1α and HIF-2α expression in EC following 24 hours of culture under these conditions (Figure 1b) The increase in expression ... Available online http://arthritis-research.com/content/8/4/R130 Figure Effect of chemical mimetics of hypoxia on CD59 expression HUVEC expression were treated with increasing concentrations of atorvastatin...

Ngày tải lên: 09/08/2014, 08:22

... secretion induced by low concentrations of taurine (10 -7 M and under) In contrast, there two components in the acid secretion induced by high concentrations of taurine (10-6 M or above) The component ... located on cholinergic neurons though cAMP pathway and partially on nonneuronal cells in the stomach In light of the findings of previous investigations together with our observations of CSAD- ... concentration ≤10 -7 M but did not completely inhibit the acid secretion induced by high taurine concentration >10-7 M It’s been long recognized that low TTX concentrations blocks nerve conduction due...

Ngày tải lên: 10/08/2014, 05:21

... personal motivation on continuance and affective commitment: 66 5.2 Effect of idealized influence on continuance and affective commitment: 67 5.3 Effect of contingent reward on continuance and ... Distribution Company introduction: FPT Distribution Company (FDC) is one of seven affiliate companies of FPT Corporation, Vietnam‟s largest informatics organization It was officially established on ... subset, or some part, of a larger population The definition of the sample is of vital importance as the results of an investigation are not trustworthy more than the quality of the population or representativeness...

Ngày tải lên: 22/10/2015, 13:43

... revealed a consistent pattern of the effect of smoking on risk of cancer deaths TABLE Characteristics of cases and two control groups: Population-based case-control study of smoking on risk of cancer ... methodological areas of control selection, it is widely accepted that the inclusion of multiple control groups selected by different criteria is preferable to only one control group.20-23 Multiple control ... assess more relationships between one or more exposures and various causes of death at one time, and use of a single control group for more than one case series can lead to saving of money and time;11-12...

Ngày tải lên: 26/10/2012, 09:48

... Effect of KNO3 Spraying on yield and yield Component of rice on Alluvial Soie in Nam Dinh- Spring Rice – 2009 ( Quinal/ha) Number of paricals/m2 Number of grain/pan 1A 1B 12 LS DO5 % of umfiiied ... Effect of KNO3 Spraying on yield and yield Component of rice on Alluvial Soie in Nam Dinh- Summer rice – 2009 ( Quinal/ha) Number of paricals/m2 1A 1B 12 LS DO5 Number of grain/pan % of umfiiied ... weight(g) Grain yield Tab 6: Effect of KNO3 Spraying on rice yield on degraded Soie in Bac Giang 2009 ( Quinal/ha) Treat Spring Rice Summer Rice Yield Response Yield Response Quintal/ha % Quinal/ha %...

Ngày tải lên: 20/01/2014, 02:20

... affiliation Demographic information was asked at the conclusion of the questionnaire The Spanish and the English version of the questionnaire are available from the authors upon request The questionnaire ... use emergency contraception among low-income post-partum women Contraception 2000, 61(6):351-357 Spinnato JA: Informed consent and the redefining of conception: a decision ill-conceived? J Matern ... reproduction, stating: "In the next part of the questionnaire we ask some questions about how the different methods of birth control work First, we will describe the stages of normal human reproduction:...

Ngày tải lên: 13/02/2014, 06:20

... forms: (1) Cr(III) in a concentration of 1000 mgykg, (2) Cr(VI) in a concentration of 1000 mgykg, and (3) Cr(III) and Cr(VI), each in concentrations of 500 mgy kg In addition to chromium, Ni(II) ... centrifugation The supernatant was analyzed using AAS to determine Cr(VI) concentrations Cr(III) concentrations were calculated by subtracting Cr(VI) concentrations from the total chromium concentrations ... simulate typical electroplating contamination conditions Ni(II) and Cd(II) were used to investigate synergistic effects of different forms of chromium on the migration of co-existing Ni(II) and Cd(II)...

Ngày tải lên: 16/03/2014, 00:07

... forms: (1) Cr(III) in a concentration of 1000 mgykg, (2) Cr(VI) in a concentration of 1000 mgykg, and (3) Cr(III) and Cr(VI), each in concentrations of 500 mgy kg In addition to chromium, Ni(II) ... centrifugation The supernatant was analyzed using AAS to determine Cr(VI) concentrations Cr(III) concentrations were calculated by subtracting Cr(VI) concentrations from the total chromium concentrations ... simulate typical electroplating contamination conditions Ni(II) and Cd(II) were used to investigate synergistic effects of different forms of chromium on the migration of co-existing Ni(II) and Cd(II)...

Ngày tải lên: 16/03/2014, 00:07

... forms: (1) Cr(III) in a concentration of 1000 mgykg, (2) Cr(VI) in a concentration of 1000 mgykg, and (3) Cr(III) and Cr(VI), each in concentrations of 500 mgy kg In addition to chromium, Ni(II) ... centrifugation The supernatant was analyzed using AAS to determine Cr(VI) concentrations Cr(III) concentrations were calculated by subtracting Cr(VI) concentrations from the total chromium concentrations ... simulate typical electroplating contamination conditions Ni(II) and Cd(II) were used to investigate synergistic effects of different forms of chromium on the migration of co-existing Ni(II) and Cd(II)...

Ngày tải lên: 16/03/2014, 00:07

... definitions of an acute exacerbation in the literature vary [2,19,28-30], indicating that there is no clear consensus on the definition of an exacerbation The application of a different definition of ... prolonged study interval, then more subjects may have experienced exacerbations Second, concerning the definition of an exacerbation, we selected the definition of an acute exacerbation of COPD ... [11,12,33] Conclusion In conclusion, we demonstrated that acute exacerbations require the use of additional medication, even in an outpatient clinic, that could be detected statistically over a 6month...

Ngày tải lên: 18/06/2014, 19:20

... definitions of an acute exacerbation in the literature vary [2,19,28-30], indicating that there is no clear consensus on the definition of an exacerbation The application of a different definition of ... prolonged study interval, then more subjects may have experienced exacerbations Second, concerning the definition of an exacerbation, we selected the definition of an acute exacerbation of COPD ... [11,12,33] Conclusion In conclusion, we demonstrated that acute exacerbations require the use of additional medication, even in an outpatient clinic, that could be detected statistically over a 6month...

Ngày tải lên: 20/06/2014, 16:20

... or absence of S9 mixture Overall, the chromosomal aberration frequencies were observed to be proportional to acrylamide concentrations of 5-50 mM Micronucleus The result of the micronucleus test ... solution (in phosphate buffer, pH 6.8) The concentration of 50% cytotoxicity was determined by microscopic observation Based on the preliminary toxicity study, the acrylamide concentrations used ... plate For positive controls, 2-aminofluorene (Sigma-Aldrich, USA) at a concentration of 10 µg/plate for TA 98 strain, sodium azide (Sigma-Aldrich, USA) at a concentration of 1.5 µg/plate for...

Ngày tải lên: 07/08/2014, 18:21

... successful bone marrow transplantation Leukemia Lymphoma 1991, 4:335-341 Atzeni F, Schena M, Ongari AM, Carrabba M, Bonara P, Minonzio F, Capsoni F: Induction of CD69 activation molecule on human ... membrane expression of CD69 [37], and this observation was confirmed in the present study This activation molecule is not constitutively expressed on neutrophils but it may be induced on these cells ... mechanism of action of anti-TNF-α mAbs in the control of inflammatory arthritis Competing interests The author(s) declare that they have no competing interests Authors' contributions FC conceived...

Ngày tải lên: 09/08/2014, 06:22

... in the cultures of human monocytes or HFC alone (b) Gel zymography detection of MMP-2 and MMP-9 in human CD14+ monocytes of normal control monocytes, in HFC, and in a co-culture of the two MMP-2 ... peripheral blood monocytes in normal subjects are consistent with previous studies demonstrating that CD147 is expressed on the surface of activated monocytes [7,22-24] The expression of CD147 on normal ... blockage of CyPA chemoattraction for the mononuclear cells by anti-CD147 antibody and AP9 was more obvious than that caused by CsA (p < 0.05) Discussion Our results on the expression of CD147 on peripheral...

Ngày tải lên: 09/08/2014, 06:23

... and after 12 months of therapy, and five out of six studies assessed the DLCO at baseline and after 12 months In one study, one-half of the patients received oral CYC and one-half of the patients ... results of our metaanalysis are based on 12 months of follow-up they may not reflect adverse events developing over longer durations of treatment or follow-up Our study has additional limitations ... (see Additional file 2) [23] Statistical analysis Pre-post comparisons were made using paired t tests Two observational studies had lengths of follow-up of 18 months [15] and of 24 months [17];...

Ngày tải lên: 09/08/2014, 13:22

... prolonged depletion of glutathione in the brain is associated with oxidative neuronal death Ischemia induces oxidative stress, leading to induction and expression of various genes in a variety of ... reaction was started by the addition of NADH, incubated at 30°C and stopped by the addition of ml of glacial acetic acid The absorbance of the chromogen formed was measured at 560 nm One unit of ... were constructed for short-term administration of the therapeutic agents just before or after IRI, while our study could be one of the recent studies for long-term prophylactic administration of...

Ngày tải lên: 10/08/2014, 05:21