effects of phl on morphologic alterations in the hippocampus following tbi
Studies on the mechanisms of the beneficial effects of herba leonuri and leonurine on traumatic brain injury in rat
... general brain morphology following TBI 57 3.1.1.2 Effects of pHL on morphologic alterations in the hippocampus following TBI 59 3.1.1.3 Effects of pHL on neuronal loss, ... GPx and GST in the cortex following TBI 78 3.3.2 Comparing the anti-apoptotic effects of pHL and Leo 79 3.3.2.1 Comparison of the effects of pHL and Leo on the expression of apoptosis-related ... 3.2.1.1 Effects of Leo on the activities of SOD, CAT, GPx and GST in the cortex following TBI 71 3.2.1.2 Effects of Leo treatment on neuronal apoptosis following TBI 73 3.3: Investigating...
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báo cáo hóa học:" Oxford unicompartmental knee arthroplasty: medial pain and functional outcome in the medium term" pptx
... Osteoarthritis, of these 30 of the 48 had radiographic Grade (bone on bone) arthritis, the remaining 18 had grade OA Of the 48 patients, four had undergone revision, four had died since implantation and ... Each prosthesis was then scored radiographically by summing the degree of deviation of the implant from perfect alignment in two planes, and adding the overhang in mm and the presence of posterior ... could be done by extending our indications and ignoring the presence of patellofemoral arthritis (if not clinically symptomatic) as suggested in the new guidelines by the Oxford group The vast...
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Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
... PRPP binds first, inducing a conformation change, then allowing the purine base to bind in accordance with the mechanism of human HPRT [19,25] This conclusion can be made based on the lack of thermal ... crystallization solutions The ligand bound was interpreted as GMP because the N2 of the base makes a hydrogen bond to a main chain carbonyl Binding of a xanthine base from XMP in the same position, would ... (Fig 1C) The 2¢OH of the ribose is hydrogen bonded to the main chain and the side chain of Asp142 (Fig 1C) Both hydroxyl groups of the ribose are involved in coordinating a putative Ca2+ ion This...
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Tài liệu Báo cáo khoa học: Studies on structural and functional divergence among seven WhiB proteins of Mycobacterium tuberculosis H37Rv pdf
... sub-stoichiometric iron content of iron–sulfur proteins is generally due to the impaired incorporation of the cluster into the protein during overexpression in E coli and ⁄ or loss during purification when conditions ... coordination sites are the likely cause of minor variations in the electronic properties, which were reflected in their absorption spectra The brownish appearance of the protein purified in the ... disintegration of the iron–sulfur cluster in each of the WhiB proteins (Fig 3C,D) Therefore, disassembly of the iron–sulfur cluster under oxidizing conditions and its stability under reducing conditions...
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Tài liệu Báo cáo khoa học: Structural and functional studies on a mesophilic stationary phase survival protein (Sur E) from Salmonella typhimurium ppt
... represent the N-terminal and C-terminal domains of the corresponding subunits D230, which is involved in crucial interactions that may be responsible for domain swapping, is shown at the top of the ... The other interactions of D234 in Aa SurE correspond to the interactions of D230 in St SurE A different set of interactions appears to promote a rigid structure leading to domain swapping in Tt ... form The shift in the position of the loop away from the metal ion leads to the formation of two interprotomer active sites where the Oe of E37 from one subunit coordinates with the metal ion bound...
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Tài liệu Báo cáo khoa học: The Mycobacterium tuberculosis membrane protein Rv2560 ) biochemical and functional studies pdf
... of new therapies and ⁄ or vaccines, or the improvement of existing ones, necessary to control this disease The identification and characterization of the proteins involved in the interaction of ... and clinical isolate strains, as well as the characterization of the high-activity binding peptide (HABP) involved in the binding to and invasion of monocytes (U937) and type II alveolar epithelial ... proteins present on the membrane for which no role in M tuberculosis invasion of the host cell has yet been determined [12,13] The infection of epithelial cells in the alveoli requires the interaction...
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Tài liệu Báo cáo Y học: Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain docx
... of this hypothesis are meager In the head-to-tail orientation, the catalytic site in the N-terminal domain of one subunit and the substrate recognition site in the C-terminal domain of the other ... forms of LPL reveal interesting features of LPL structure, including the conformational change in the active center, the critical sites for heparin binding, and the orientation of dimerization Investigation ... of the LPL C-terminal domain A cDNA segment corresponding to the C-terminal domain of LPL was placed under the control of the T7 promoter in the pET4 vector (Novagen Inc., Madison, WI, USA) In...
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Báo cáo khoa học: Comparative biochemical and functional studies of family I soluble inorganic pyrophosphatases from photosynthetic bacteria potx
... in strong ionic interactions mediated by Mg2+ [2,19] Changes in the residues involved in the interactions between subunits could explain the unusual oligomeric states found for some photosynthetic ... assay conditions) The reaction was started by the addition of enzyme, and the PPi released after 10 was determined When the efficiencies of other divalent metal cations as cofactors were tested, the ... and DNA manipulation The reaction mixture for PCR amplification of the ppa gene from Synechocystis sp PCC 6803 (50 lL) contained 50 pmol of each of the following two pairs of oligonucleotide primers:...
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báo cáo hóa học:" Functional significance of the signal transduction pathways Akt and Erk in ovarian follicles: in vitro and in vivo studies in cattle and sheep" ppt
... PG: Effects of active immunization of sheep against an amino terminal peptide of the inhibin αC subunit on intrafollicular levels of activin A, inhibin A and follistatin Journal of Endocrinology ... LH-induced increase was attenuated by inhibition of Erk and completely blocked by inhibition of the Akt pathway Conversely, progesterone production increased in response to inhibition of the ... Erk signalling pathways in mediating the effects of the gonadotropins and IGF on follicle cell function and on follicular development The stimulation of inhibin-A, activin-A, follistatin, oestradiol,...
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Báo cáo y học: "Functional outcome of nerve transfer for restoration of shoulder and elbow function in upper brachial plexus injury" potx
... supraspinatus muscle which is only an abductor attracts all the axons and reduces the potential of reinnervation of the external rotators The other explanation is, the antagonistic muscle- for instance, ... months (range 1/2 months to months) Figures 3, 4, show clinical photograph of patient with good recovery of flexion at the elbow The details of the patients and the final grading of their elbow and ... with the transfer of a motor branch of the triceps muscle to teres minor it resulted in good recovery of external rotation with average of 75% of the normal range They felt that increasing the...
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Báo cáo y học: "Combination of histopathological and electromyographic patterns can help to evaluate functional outcome of critical ill patients with neuromuscular weakness syndromes" docx
... irreversible Among survivors the absence of CMAPs on electrophysiological examination could suggest prolonged functional disability Because of the lack of sensitivity of clinical examination in such ... in all of these patients to determine the cause of limb weakness and diaphragm dysfunction The medical committee of the hospital approved the study, and informed consent was obtained from the relatives ... use of electromyography and clinical examination without obtaining neuromuscular biopsy findings may lead to some patients being diagnosed as having CIP only [2,11] Therefore, such examinations...
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Báo cáo y học: "Retrospective agreement and consent to neurocritical care is influenced by functional outcome" ppt
... by shortcomings during the informed-consent process for planned procedures [9] Consent to neurointensive care measures the individual’s satisfaction with being alive Other studies of nonneurologic ... this discussion Consent to neurocritical care declines with increasing disability However, in patients who died in the course of the disease, increased rates of consent were presumed by the families ... delays the decision to limit treatment until severe complications occur during the course of the disease [22,31,32] The finding that patients consent to neurocritical care mainly if the functional...
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Multi manifold diffeomorphic metric mapping for cortical registration with its applications in brain structural and functional studies
... and inter-ROI connections in the frontal networks are associated with improved response inhibition and memory functions during early childhood These findings show the importance of frontal regions ... brain is the center of the human nervous system and the cerebrum, as the largest and most prominent part of the human brain, is the control center of it It is 85% of the weight of a human brain ... regions of interest (ROIs) need to be chosen and the relationship of them to the rest of brain is then defined by correlation or regression It is applied in the 16 2.3 Resting State Functional...
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Structural and functional studies of VP9, a novel nonstructural protein from white spot syndrome virus
... ascertain the exact position of each atom in the asymmetric unit of the crystal Calculation of electron density is dependent on two main factors; the amplitude and the phase of the diffracted beam These ... the production of amplified products during each cycle of the PCR reaction It is one of the technologies of the genomic age and has become the method of choice for detection of gene expression ... study the transcription of viral IE genes, viral infection is induced in the presence of a protein synthesis inhibitor, usually cycloheximide (CHX), which prevents de novo protein synthesis by inhibiting...
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Structural and functional studies on type III and type VI secretion system proteins
... (Frithz-Lindsten et al., 1997) One of the hallmarks of Pseudomonas infection is epithelial injury in infected lungs Lung pathology in murine infection models requires a functional cytotoxin, ExoU, ... protein to the sec machinery at the inner membrane Once the protein reaches the periplasm with the help of the sec system, the N-terminal signal sequence gets cleaved off Upon contact with the ... Most of the E coli strains are harmless and are found in the intestines of mammals The harmless strains are part of the normal flora of the gut, and can help their hosts by producing vitamin K2,...
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Depression, cognitive impairment and physical functional outcome and their associated factors in stroke patients in community hospital care
... because of the complications they had developed during their hospitalization: (1) Diagnosis of the medical complication/s (2) Date of medical complication/s The information on the following variables ... are continent 89 Urinary incontinence on admission is associated with poorer functional outcome.91 29 Stroke patients with urinary incontinence have more chances of mortality than the continent ... before the stroke onset They had assessed dementia in the patients on the basis of 19 clinical examination using DSM-IV criteria In their research study they found that the significant correlates of...
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Báo cáo y học: "Characterization of N200 and P300: Selected Studies of the Event-Related Potential Salil H. Patel 1 and Pierre N. Azzam 2"
... effects of aging on the N2b component and, thus, upon selective information processing as a whole In one oddball detection study involving the effects of color deviation on N2b elicitation in subjects ... deviated from the standard in the intensity of the first component and the glide direction of the second constituent The number of distinct MMN components elicited by this double deviation was found ... presentations This suggests the contingency of the N2b amplitude not upon the recognition of the actual deviant targets but instead upon the plausibility of target differentiation [27] In visual...
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Tài liệu Physical health and functional ability of an elderly, population in Sri, Lanka doc
... informant was present, assessment of the informant of the health status of the elderly person was obtained Results The non-response rate for the study was only 1.7% In response to the question ... Using this index, the proportion "feeling healthy" was 43% which is low when compared with similar observations made in other countries in the region: 56% in Myanmar, 84% in Indonesia and 62% in ... 6) Informants were present in 1167 (97%) of the interviews Comparison of the physical health rating made by the informant with 'selfiassessment' indicate that the elders rate their level of health...
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Tài liệu Báo cáo khoa học: Interleukin-1-inducible MCPIP protein has structural and functional properties of RNase and participates in degradation of IL-1b mRNA doc
... to the PIN domain, was removed from the entire coding sequence of the MCPIP gene The coding sequence lacking the PIN domain was obtained in two steps First, the fragment of 423 bp situated in ... or its conversion into translationally active forms by the action of strong stimulants, such as endotoxin (LPS) One of the regulatory sequences involved in determining mRNA half life are the AREs, ... fragment was cloned into pcDNA3 containing the first fragment at the BsaI ⁄ EcoRI restriction sites A genetic construct with mutation of two conserved amino acids residues within the PIN domain (D141A...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25