effect of liver disease on pharmacokinetics

... lower than that of Tk-RNase HII Construction of mutant proteins of Sc-RNase H2* The Gly37 fi Ser mutation is the only disease- causing mutation identified in the catalytic subunit of human RNase ... values of this residue are (80.8°, 43.8°) According to the statistical analysis of the backbone conformational angles by Nicholson et al [35] and designation by Efimov [36], the backbone conformation ... From the plot of the equilibrium binding responses as a function of the concentrations of the proteins, the KD value was determined using steady state affinity program of biaevaluation software (Biacore)...

Ngày tải lên: 17/03/2014, 17:20

... to control for other confounding variables as well as the detection and evaluation of any interaction effect between groups and time/intervention Conclusions In conclusion, our study demonstrated ... values are in degrees of motion AROM - Ankle range of motion; KROM - Knee range of motion; HROM - Hip range of motion Huisinga et al Journal of NeuroEngineering and Rehabilitation 2010, 7:25 http://www.jneuroengrehab.com/content/7/1/25 ... flexion at heel contact and overall smaller hip range of motion, while decreased strength indicates that control of the ankle range of motion was reduced such that increased plantarflexion occurred...

Ngày tải lên: 19/06/2014, 08:20

... Journal of NeuroEngineering and Rehabilitation 2005, 2:23 http://www.jneuroengrehab.com/content/2/1/23 disease- related, and not simply a consequence of bradykinesia Introduction Falls are one of the ... variability of the stride time and swing time, compared to controls (see Table 1) Effects of gait speed on level ground Table summarizes the effects of walking at a self-selected slow speed on gait on ... cardio-vascular disease, respiratory disease, uncontrolled hypertension, diabetes or symptomatic peripheral vascular disease, other neurological disease (or PD in the case of the controls), dementia...

Ngày tải lên: 19/06/2014, 10:20

... absorption rate constant, A: zero time plasma drug concentration intercept of regression line of absorption phase, β: overall elimination rate constant, B: zero time intercept of the regression line ... drug concentration at time t, B is the zero time intercept of the regression line of the elimination phase, A is the zero time plasma drug concentration intercept of the regression line of the ... duration of pharmacological action, ClB: total body clearance; Vd(area): volume of distribution based on the total area under the plasma drug concentration time curve; Vd(B): volume of distribution...

Ngày tải lên: 07/08/2014, 20:23

... examined consisted of severe calorie restriction along with vitamin supplements and administration of human chorionic gonadotropin (hCG), a hormone that encourages metabolic utilization of visceral ... Lundman P, Eriksson MJ, Silveira A, Hansson LO, Pernow J, Ericsson CG, Hamsten A, Tornvall P Relation of hypertriglyceridemia to plasma concentrations of biochemical markers of inflammation and endothelial ... program on the level of cholesterol in plasma Regression analysis was conducted between body composition parameters and lipid profile parameters The mass of body fat (BF) correlated strongly with...

Ngày tải lên: 25/10/2012, 10:51

... touch feel of herbs -learning and description of the smell of ethnic spices -red and green chili sauce -recapitulation of contents of the earlier lessons -practical exercises on using one’s senses ... sessions one group of the children (N = 35) received a lesson on the sense of taste, another group (N = 34) received a lesson on the sense of smell and the third group (N = 40) received no lesson ... was present in one of the lessons in the first education wave For the control group the corresponding change was 0.56 (effect of education, p = 0.24) Mean change in the number of positive answers...

Ngày tải lên: 03/04/2013, 21:07

... tr.106-108 Ashley D.A., Doss B.D., and Bennett O.L (1965) Relation of cotton leaf area index to plant growth and fruiting, Agronomy Journal 57, pp 61-64 Gomez K Wanchai A and Gomez Arturo A (1984) ... A (1984) Statistical Procedures for Agricuktural Research, Awiley Interscience Publication JOHN WILEY & SONS Michigan State University (1986) MSTATC: Microcomputer statistical program experimental ... lá/ngy) mật độ gieo trồng khác nhau, Ninh Thuận, vụ đông xuân năm 2008/2009 Hiu sut quang hp giai on (ngy sau gieo) Mt (vn cõy/ha) 46 - 55 56 - 65 66 - 75 76 - 85 2,5 8,68 8,69 7,42 6,84 5,0 6,61...

Ngày tải lên: 28/08/2013, 14:15

... PCB solutions Effect of Initial PCB Concentration The results of the degradation of PCBs at different initial concentrations are shown in Figs and In all the initial PCB concentrations used, ... degradation In this study, effective degradation was obtained at H2O2 concentration of about 2800 ml (of the 30%H2O2 solution) per liter and initial PCB concentration of about 40 ppm The initial pH of ... degradation in this study was basically photolysis The objective of this study is to determine the effects of initial H2O2 concentration, initial pH of the solution and initial PCB concentration on...

Ngày tải lên: 05/09/2013, 09:08

... in metal concentration in the sediments of receiving watersheds based on the relatively higher concentrations of roadside deposits compared with those of sediments Table Concentration of acid-soluble ... nitric acid digestion ICP-MS model SPQ-9000 (Seiko Instruments) was used for the determination of lead concentration Chloride ion concentrations and suspended solid concentrations (SS) were also ... intrusion was found for the sampling locations based on the completely fresh water level of chloride ion content smaller than 110mg/L in the samples Table gives the results of metal concentration of...

Ngày tải lên: 05/09/2013, 09:08

... Navier-Stokes equations, i.e the continuity equation, the mass conservation equation for each phase yields the volume fraction (r ) and along with the momentum equations the pressure distribution inside ... by the divergence of the mass flux through diffusion and convection Multiple species are considered in the gas phase only, and the species conservation equation in multicomponent, multi-phase ... tension (N/m) The liquid phase consists of pure water, while the gas phase has multi components The transport of each species in the gas phase is governed by a general convection-diffusion equation...

Ngày tải lên: 05/09/2013, 14:58

... The effect of variable suction on free convection on a vertical plate in a porous medium J Math Phys Sci 1992, 29, 559 [8] Mansutti D., Pontrelli G., Rajagopal K R Steady flows of non-Newtonian ... skin friction at the wall On the other hand, the effect of increasing suction parameter is to enhance the magnitude of both the components of skin friction at the wall A growing suction parameter ... the effect of suction parameter α and the Reynolds number Re respectively on the temperature of the flow field A careful observation of the above figures shows that the effect of growing suction...

Ngày tải lên: 05/09/2013, 14:58

... (Online) ©2013 International Energy & Environment Foundation All rights reserved International Journal of Energy and Environment (IJEE), Volume 4, Issue 2, 2013, pp.211-218 217 Conclusion Only ... performance of a single-sloped basin still with aninherent built-in additional condenser Desalination 142 (2002) 19-27 [13] Khalifa AJN, Hamood AM On the verification of the effect of water depth on the ... The objective of this work is to investigate the effect of brine depth on the productivity and efficiency of solar still under laboratory conditions Table shows a summary of some of the studies...

Ngày tải lên: 05/09/2013, 16:10

... Gumus M Effect of injection timing on the exhaust emissions of a diesel engine using diesel–methanol blends Renewable Energy 2009, 34, 1261–1269 Samion N.A Emissions of continuous combustion from ... amount of CO2 in the exhaust emission is an indication of complete combustion of fuel [13,21] The CO2 emission of DF increased slightly, when EGR was operated While, the CO2 emission of JBD blends ... Variation of EGT with various EGR rates 3.2 Emission characteristics 3.2.1 CO emission Generally, CO emission is forming resulted of incomplete combustion of fuel However, if the combustion is...

Ngày tải lên: 05/09/2013, 16:11

... overall effects of injection timing on combustion, engine performance and emissions are discussed in this section 3.1 Effect on brake thermal efficiency The effect of injection timing on engine ... depends on the combustion properties of the fuel Figure Effect of injection timing on brake thermal efficiency 3.2 Effect on brake specific fuel consumption The brake specific fuel consumption is ... combustion in the cycle leading to lower exhaust temperature Figure Effect of injection timing on exhaust temperature 3.4 Effect on power and mean effective pressure The effect of injection timing on...

Ngày tải lên: 05/09/2013, 16:11

... Lục Văn Hai_Trung-Anh strongly, and many buildings and big houses are grown up a lot.Morever, the growth of economy has given a lot of advantages by making people richer, healther, ... of advantages by making people richer, healther, and freer to enjoy their lives.I always pride of my city whenever I talk about him.I wished that could work at my hometown after finishing at...

Ngày tải lên: 18/01/2014, 07:20

... 4: Effect of KNO3 Spraying on yield and yield Component of rice on Alluvial Soie in Nam Dinh- Spring Rice – 2009 ( Quinal/ha) Number of paricals/m2 Number of grain/pan 1A 1B 12 LS DO5 % of ... 5: Effect of KNO3 Spraying on yield and yield Component of rice on Alluvial Soie in Nam Dinh- Summer rice – 2009 ( Quinal/ha) Number of paricals/m2 1A 1B 12 LS DO5 Number of grain/pan % of ... weight(g) Grain yield Tab 6: Effect of KNO3 Spraying on rice yield on degraded Soie in Bac Giang 2009 ( Quinal/ha) Treat Spring Rice Summer Rice Yield Response Yield Response Quintal/ha % Quinal/ha...

Ngày tải lên: 20/01/2014, 02:20

... estimates of the effect of separation on child wellbeing Regressions rely on strong functional form assumptions (linearity between the covariates and the outcome of interest) In the present context ... union dissolution between unmarried parents (defined as the dissolution of a romantic relationship) has a causal effect on child health We focus on the effect of parental relationship dissolution ... observations whose propensity score belongs to the intersection of the supports of the propensity score of treated and controls Imposing the common support condition in the estimation of the propensity...

Ngày tải lên: 12/02/2014, 11:20

... yields monotonic increase in the saturation magnetization of Niferrite which may be due to the substitution of Ni2+ ions by Co2+ on the octahedral sties Therefore, the increasing Co2+ concentration ... expression corresponds to the contribution of magnetocrystalline anisotropy of material, the second one is given by shape anisotropy of crystalline particles (domains) and the third one is orginated ... successfully by co-precipitation method X-ray diffraction study shows the presence of cubic spinel The increase of Co2+ ion concentration yields the monotonic increase of MS, HC Magnetic measurements...

Ngày tải lên: 13/02/2014, 04:20

... salience One determiner of whether attentional or propositional effects are dominant is the type of information provided by the accented constituent Because nonpronominals contribute discourse content, ... Conference of the Association for Computational Linguistics, 1987 Janet Cahn The Effect of Intonation on Pronoun Referent Resolution Draft, 1990 Available as: Learning and Common Sense TR 94-06, M.I.T ... Phonetics of English Intonation Ph.D thesis, Massachusetts Institute of Technology, 1980 Janet B Pierrehumbert and Julia Hirschberg The Meaning of Intonation Contours in the Interpretation of Discourse...

Ngày tải lên: 20/02/2014, 22:20