effect of impurities on the surface state in equilibrium

... creatinine in the apical compartment in the absence of quinidine Creatinine transport was significantly (p < 0.05) inhibited in the presence of quinidine at 30 minutes The concentration of [2-14C] ... absence of acyclovir (22 to 89 μM) In contrast, the concentration of [2- 14 C] creatinine was decreased in the apical compartment in the presence of quinidine, compared to the concentration of [2-14C] ... absence of acyclovir (22 to 89 μM) In contrast, there was a decrease in the concentration of [2-14C] creatinine in the apical compartment in the presence of quinidine or cimetidine, compared to the...

Ngày tải lên: 18/06/2014, 16:20

... 48 h of incubation time (Fig 2) However, the taxol concentration used was critical for the level of cytokine production; μg/ml of taxol induced only marginal production of these cytokines These ... closely involved in the survival and maturation of DCs [11,17,20] To investigate further the mechanisms of taxol-induced changes, the viablity of TPCK, an inhibitor of the serine protease that inhibit ... viability These findings provide a basic rationale for the use of taxol in DC immunotherapy and insights into the development of combinational DC therapies with other anticancer drugs that not harm the...

Ngày tải lên: 07/08/2014, 23:22

... personal level of PM2.5 absorbance compared with the personal levels of NO2 For the latter, 316 being in the rainy season increased the personal concentration of NO2 by 1.8 ppb, implying a stronger 317 ... lead to only the 388 stronger predictors remaining in the final model of the determinants of personal exposures SC M AN U TE D 389 RI PT 371 Overall, the models for the determinants of personal ... examined the correlation between 277 the average of the two monitoring stations with the repeated measurements of study participants Figure 278 shows the results of the analysis of the correlation...

Ngày tải lên: 13/09/2015, 17:48

... Women
with
breast
cancer
have
a
fivefold
increased
incidence of developing
cancer
 in the contralateral
breast
(46). In a
meta-analysis of 55
trials on tamoxifen
therapy
 for
early
breast
cancer, the incidence
rate of contralateral
breast
cancer in women
 ... Genistein,
an
isoflavone
found in soy,
was
found
to
inhibit
tyrosine
kinase
activity of the epidermal
growth
factor
receptor in vitro
(104).
Urinary
excretion of isoflavonic
 phyto-oestrogens,
as
an
indicator of phyto-oestrogen
intake,
was
lower in breast
 ... cancer of 0.39
(95%
CI
0.19-0.8)
compared
to
women in the lowest
tertile.
Recent
 results
from the prospective
Singapore
Chinese
Health
Study
again
confirmed the finding of risk
reduction
with
high
soy
intake
(108). In a
subset of this
cohort
who
...

Ngày tải lên: 05/10/2015, 21:29

... are able to control the protein synthesis machinery in cells of the vertebrate host, which could explain the differences in the levels of expression observed in our study The effect of antibodies ... used in the real time PCR reactions, demonstrating that there was no gDNA contamination PCR reaction triplicates showed no major differences among them and expression levels of the internal control ... 2006, In order to investigate if antibodies were exerting an effect on invasion, serial dilutions of mAb anti-CSP were tested in the culture medium After synchronisation, the percentage of schyzonts...

Ngày tải lên: 02/11/2012, 10:14

... Decreasing the Gd3+ concentration on the trans side of the channel by addition of equimolar EGTA resulted in the recovery of the channel from the inhibition (Fig 3D) in less than one minute The ... can bind to the Ca2+-binding sites of different membrane proteins we investigated the effect of this ion on the RyR1 using different techniques [17] Effect of gadolinium on RyR1 Fig Effect of cis ... tested the effect of Gd3+ on the luminal side of the reconstituted channel To decrease the possibility of the applied Gd3+ acting on the cytoplasmic site of the RyR1 after (or during) passing through...

Ngày tải lên: 19/02/2014, 16:20

... as a sort of ‘art painting’ 3.3 Procedure 3.2 Online Survey The findings published in this paper are based on an online survey and part of a larger study on the role of aesthetic within data visualization ... Latency in Erroneous Response Complimenting accuracy ratios are timings of erroneous response and speed of completion, measuring the duration in which a participant probed in expectation of retrieving ... N Cawthon and A Vande Moere, "A Conceptual Model for Evaluating Aesthetic Effect within the User Experience of Information Visualization," in Tenth International Conference on Information Visualisation...

Ngày tải lên: 07/03/2014, 17:20

... also contribute to the conformational stability of holo-lMb Consistently, they are maintained over the 1.5 ns of the simulation (Fig 2) A comparison of the hydrogen-bond distances in Figs and indicates ... Asp60 in apo-lMb based on the structure at approximately 0.5 ns of the simulation coincides with the beginning of the unfolding of helix E described above (Fig 2) Therefore, the formation of this ... proteins [19–21] The results reported here strengthen the notion of the structural complexity of proteins in the denatured state and provide an example of the role of non-native ion pairs in protein...

Ngày tải lên: 16/03/2014, 06:20

... proteins in the purified DNA Fig Effect of heliquinomycin on DNA helicase activity (A) Top: effects of increasing concentrations of heliquinomycin (HQ) on the DNA helicase activities of the MCM4/6/7 ... kDa Fig Effect of increasing concentrations of heliquinomycin (HQ) on the formation of the MCM4/6/7 complex The MCM4/6/7 complex was incubated in the presence or absence of heliquinomycin and ... synthesized only in the presence of the above complex The synthesis of the RNA primer was inhibited in the presence of heliquinomycin at an IC50 value of 25 lm The DNA polymerization activity of...

Ngày tải lên: 23/03/2014, 04:21

... ionizing residue that is involved in binding the 2¢-phosphate of NADPH The effect of pH on the initial rate kinetics is consistent with two ionizing groups in the enzyme active site involved in ... to give the inhibition constant for the slope effect For inhibition constants involving intercept effects, the reciprocal of the apparent Vmax was plotted against the concentration of inhibitory ... role in binding NADH In the case of human BVR-A, we have suggested that the protonation state of Glu75, may effect the interaction with Arg44, which is a key residue involved in binding the 2¢-phosphate...

Ngày tải lên: 23/03/2014, 05:22

... transform the standard deviation of the coefficient in the original equation to the standard deviation of the impact on population probabilities For example, a listed standard error of 0.0098 on the ... independence of years indirectly by evaluating the sensitivity of the results from the first part of the model using conditional logit, a method that does not assume independence We performed conditional ... days Effects on total days for each variable were calculated by multiplying three parts: the effect on the probability of a year with at least one day, the mean effect on days conditional on any...

Ngày tải lên: 23/03/2014, 08:21

... reported the influence of caffeine on osteoporosis, but the effects of coffee on bone metabolism remain controversial [26,27] Hypotheses to explain these associations have centered on the caffeine content ... [30] In the presence of 10 mM caffeine, the viability of osteoblasts was decreased and the residual cells lost their reaction to ALP staining and von-Kossa staining (Figs &3) The formation of ALP ... cultured with caffeine for one day, there was no statistically significant change in the formation of formazan; while in the 100 mM to mM concentration of caffeine, the formation of formazan was...

Ngày tải lên: 20/06/2014, 00:20

... lines show G in the presence of the e-ph interaction with ω0 = 2Γ, ω0 = Γ, or ω0 = 0.5Γ The e-ph interaction increases the conductance in the region between the original peaks, shifting these peaks ... e-ph interaction, while the vertex corrections of the e-ph interaction vanish when the tunnel coupling is symmetric We also take into account the RPA type dressing of the phonon, resulting from ... conductance G0, in the absence of e-ph interaction (b) The additional conductance due to the e-ph interaction, Gint(ω) = GH(ω) + Gex(ω), for the same parameters as in (a) interaction, Gint, for the same...

Ngày tải lên: 21/06/2014, 05:20

... investigated the effect of the dropping rate of NaOH into the precursor solution, droplet size, and amount of the NaOH solution and the hydrothermal reaction time on the hydrothermal formation of the ... by the random bulging and smearing of the nanowhisker surface The deformation of the nanowhiskers in the presence of electron beam reveals the amorphous nature of the as-synthesized MBH-NON sample, ... effect of sample processing conditions on the morphology, we performed the sample synthesis in open air instead of in an autoclave, where the precipitate of the starting materials was heated in open...

Ngày tải lên: 22/06/2014, 00:20

... polymerization of conducting polymers These findings may provide valuable information in the template free synthesis of many other nanostructures The investigations on in uence of other parameters ... particles of varying sizes is observed; the later being in the range of 20–30 nm The spectral investigations also highlight the differences in the conformation, which govern the extent and nature of ... coupling between neighbouring PNA rings [9] It can be concluded that the presence of acidic conditions strongly in uences the conformation of the PNA Nanoscale Res Lett (2008) 3:45–48 chains In...

Ngày tải lên: 22/06/2014, 06:20

... polymerization of conducting polymers These findings may provide valuable information in the template free synthesis of many other nanostructures The investigations on in uence of other parameters ... particles of varying sizes is observed; the later being in the range of 20–30 nm The spectral investigations also highlight the differences in the conformation, which govern the extent and nature of ... coupling between neighbouring PNA rings [9] It can be concluded that the presence of acidic conditions strongly in uences the conformation of the PNA Nanoscale Res Lett (2008) 3:45–48 chains In...

Ngày tải lên: 22/06/2014, 19:20

... Correlation of the dipole moment with the Hammett constants of the substituents It is evident from the table II that electron-donating substituents on the phenyl ring increase the pKa of anilines amino ... Correlation of QN with the Hammett constants of the substituents According to the table 2, electron-donating substituents decrease the dipole moment of compounds and electron-withdrawing substituents ... framework, thereby shortening d(CN) The accompanying loss of electron density from the amino nitrogen atom decreases the pKa of the amino group Conversely, electron-donating substituents favor pyramidal...

Ngày tải lên: 23/07/2014, 13:21

... exist a lot of data on the liming effect on the soil chemistry changes but data on the liming effect on the mineral nutrition of forests are scarce Thus, the mineral nutrition of mountain Norway ... of forest conditions after liming showed that liming has both positive and negative effects on the forests Thus the long-term monitoring of forest conditions after liming is required There ... limed in order to compare the liming effect on the mineral nutrition of spruce stands METHOD Research on the mineral nutrition of limed and not limed Norway spruce stands was conducted at the study...

Ngày tải lên: 07/08/2014, 10:21

... strong influence on the shape of as-formed particles by governing the growth rate of various crystallographic surfaces and create orientations in crystals formation [30] With the exception of ... [32], the truncations occur in order to reduce the surface energy of the particles therefore making the resultant particles more stable CONCLUSIONS The size, size distribution and to some extent the ... patterns of these magnetites are shown in Figure The XRD results also confirmed the purity of the products via the absence of other phases of iron oxide such as maghemite or hematite in samples...

Ngày tải lên: 07/08/2014, 14:20

... helped the germination of seeds present in the soil in contrast with the number of seeds which germinated in the control area In the same way, the greatest number of germinated species was always in ... observed in this area that the germination increase continued during the second year after the fire must sent The total number of seedlings in the burned area : 2 (16 015 seeds/m 14 648 seeds/m in the ... than in the control The same occurs if the number of species germinating in the surface stratum is compared with those that so in the deep one Thirty-five species were found, corresponding to...

Ngày tải lên: 08/08/2014, 14:21