ecstasy as a case in point

... this domain was found in some closely related bacterial species, but mainly in nonvertebrate animals, and invariably connected via a linker to an animal-type a- amylase (listed in Table S1), as shown ... Searches in databases Using the putative C-terminal domain of C fluminea as a query, sequence databases were searched by blastp and tblastn for the occurrence of domains similar to the P haloplanktis ... FEBS 2335 Linkers in modular a- amylases G Feller et al Table Amino acid frequencies (%) in a- amylase linkers, in a set of globular proteins, in the Swiss-Prot databank and in intrinsically unstructured...

Ngày tải lên: 14/02/2014, 18:20

... with a mass in her left breast 21 years after being diagnosed with invasive ductal carcinoma of the right breast, treated by a right mastectomy and axillary dissection followed by radiotherapy and ... Based on imaging, the diagnosis was a probable angiosarcoma Due to the presence of a pacemaker for cardiac arrhythmia and full anticoagulation therapy for a pulmonary embolism, magnetic resonance ... hypertension, a pacemaker for cardiac arrhythmia and was also treated with acenocoumarol for a pulmonary embolism two years ago Magnetic resonance imaging (MRI) was not feasible due to the pacemaker We...

Ngày tải lên: 10/08/2014, 23:20

... Sasaki H, Takada E, Sunagawa M, Masawa N: Fine needle aspiration of toxoplasmic lymphadenitis in an intramammary lymph node A case report Acta Cytol 2001, 45:259-262 Siriwardana et al Journal ... presenting as a swelling in the axillary tail of the breast and a palpable axillary lymph node mimicking malignancy: a case report Journal of Medical Case Reports 2011 5:348 Submit your next manuscript ... [2] Page of Conclusions Toxoplasmosis rarely presents as a mass in the axillary tail of the breast and may be considered as a differential diagnosis in patients presenting with axillary lymphadenopathy...

Ngày tải lên: 10/08/2014, 23:22

... signal transduction cascade that recruits an ADP-ribosylation factor guanine nucleotide exchange factor (such as ARNO) to the apical plasma membrane ARNO facilitates ADP-ribosylation factor activation ... disease Because HXA3 may play an important step underlying the pathophysiology of in ammatory diseases, such as in ammatory bowel disease, the investigation of human 12-LOX genes at mucosal surfaces, ... Protein kinase Calpha-dependent increase in Ca2+-independent phospholipase A2 in membranes and arachidonic acid liberation in zymosan-stimulated macrophage-like P388D1 cells Biochem Pharmacol 63,...

Ngày tải lên: 19/02/2014, 02:20

... or as later invasive stage [46–48] Thus, in most cases, choriocarcinoma has the appearance of trophoblast, being predominantly syncytiotrophoblastic or cytotrophoblastic Some cytotrophoblastic ... island and cell columns, is formed which maintains the ability of proliferation and invasion Choriocarcinoma is a malignant neoplasm that represents the early trophoblast of the attachment phase ... IgG and ECL development [30] Reverse-transcriptase-polymerase chain reaction Total RNA from choriocarcinoma cell lines was isolated by using RNeasy kit (Qiagen, Vienna, Austria) Three micrograms...

Ngày tải lên: 20/02/2014, 23:20

... oncology Using tools in areas including clinical trials management, tissue banks and pathology, imaging, and integrative cancer research, researchers and clinicians are able to analyze massive amounts ... prospective databases that allow for collection and analysis of clinical and disease biomarker data that will ultimately be used for clinical trial-matching and potentially as a clinical decision-making ... insurance claims databases, though not as detailed and not as expensive to generate as clinical databases, are another potentially valuable source of information on health outcomes and associated...

Ngày tải lên: 15/03/2014, 00:20

... Dewpura et al endogenous inhibitor, a catalytic domain characteristic of serine proteases and a C-terminal Cys- and His-rich domain implicated in enzyme stability and protein– protein interaction ... reducing plasma LDL cholesterol [7,22] As is the case with ‘gain-of-function’ PCSK9 variants, not all ‘lossof-function’ variants can be attributed to a single mechanism, in this case, reduced plasma ... the prodomain, the common naturally occurring A5 3V variation that has no significant effect on plasma cholesterol levels and the R46L variation, a naturally occurring variant associated with hypocholesterolemia...

Ngày tải lên: 16/03/2014, 06:20

... carrying out a conversation and had been residing in the NHs for at least months We defined mentally intact as having a Clinical Dementia Rating (CDR) ≤ 0.5 [22], which was assessed by trained nurses ... occupational therapy and participation in the political, cultural and religious arenas In this way, health care professionals can encourage the residents to engage in activities in the NH and in activities ... items ranging from lowest physical health score associated with marked limit in performing all physical activities including bathing and dressing due to health, to high physical health, associated...

Ngày tải lên: 18/06/2014, 19:20

... Golden A, Brashear J, Robinson J, Rapp M, Klass M, Ostrow DH, Mandecki W: Recombinant mouse-human chimeric antibodies as calibrators in immunoassays that measure antibodies to Toxoplasma gondii ... results in the medical laboratory Eur J Clin Chem Clin Biochem 1996, 34:983-999 13 Koshy A, Grover S, Hyams KC, Shabrawy MA, Pacsa A, al-Nakib B, Zaidi SA, al-Anezi AA, al-Mufti S, Burans J, Carl ... was evaluated by SDS-PAGE analysis The bands that showed the maximum staining were observed at 50 kDa and 25 kDa, and these bands corresponded to the molecular weights of heavy and light chains...

Ngày tải lên: 12/08/2014, 04:20

... interpretation, and drafted the manuscript LE was the lead for statistical analysis RT was involved in study design and data interpretation SR was involved in study design and data interpretation All authors ... Allmiral LE and RT are employees of GSK SR has consulted or participated in advisory boards for: Able Associates, Adelphia Research, Almirall/Prescott, APT Pharma/Britnall, Aradigm, AstraZeneca, ... measurements Bland Altman plots for sputum percentage and numbers/ ml at baseline and year are shown in Figure For percentages, the mean change was a 3.5% increase at year compared to baseline, with...

Ngày tải lên: 12/08/2014, 11:22

... string of such co-ordinates A polygon is a closed line The grid-based format of data is captured as information of each quadratic cell in a screen and could be looked at as a photo of the area ... structure of a Geographical Information System models of the real world using points, lines and polygons Vector digitising captures a point as a x, y co-ordinate, while a line is captured as an ordered ... provide maps which show the spread of the disease by displaying the maps as a movie The GIS can also be incorporated in a real time outbreak notification, as done in an eradication program of the Aujeszky’s...

Ngày tải lên: 12/08/2014, 15:20

... protocol planning, was a primary data gatherer and drafted the manuscript SC participated in data collection and statistical analysis VN performed statistical analysis LB participated in data collection ... was used to identify independent variables associated with death Variables that were associated with mortality in univariate analysis were considered for inclusion in the model, whereas parameters ... ventilation, length of stay, and the number of failing organs Statistical analysis Continuous variables' data are expressed as mean value ± SD Bi-variate hypotheses involving continuous variables...

Ngày tải lên: 12/08/2014, 22:22

Ngày tải lên: 12/08/2014, 23:20

... Cardiac Arrhythmia Suppression Trial (CAST) Investigators: Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial ... serve as a potential surrogate end -point by predicting clinical benefit, the authors found that 57% of the DrotAA effect was explained by the change in protein C levels The authors also demonstrated ... that survival in those with normal protein C levels was higher in those patients treated with activated protein C, as compared with control individuals To be a valid surrogate end -point, there...

Ngày tải lên: 13/08/2014, 10:20

... Therefore, a The parameter À determines how easily mobility itself can change The increase in this parameter accelerates the growth of the mean character value as well as the standard deviation The increase ... and power of certain organs in a variety of environments However, each case has equally convincing counter-arguments Speculations on the advantages of a large or small body size when explaining ... the character value also grow, ie the level of interspecies variation in the character value increases of species with the final stationary distribution retains a large share low character value...

Ngày tải lên: 14/08/2014, 19:22

... classes: Class I AP Endonucleases Class I AP endonucleases are also known as AP Lyases (or β-lyases) as they process the AP sites by the β-elimination reaction, which involves the removal of a ... agents including chemotherapeutic agents Removal of the damaged base by a DNA glycosylase creates an apurinic / apyrimidinic (AP) site AP endonuclease1 (Ape1), a critical component in this pathway, ... unconditionally welcoming me into your family and for always treating me like a daughter and a sister Lastly and most importantly, I want to acknowledge my mum Ranjana Bapat and my late father, Ajit Bapat...

Ngày tải lên: 24/08/2014, 13:10

... using a new data set Journal of Banking and Finance 33, 254–262 Patel, Sandeep A. , Balic, Amra, Bwakira, Liliane, 2002 Measuring Transparency and Disclosure at Firm Level in Emerging Markets Working ... research assistance We thank Pedro Matos and Miguel Ferreira for sharing their data on which Indian firms are included in the Morgan Stanley Capital International Index We also thank the Dean's ... Governance in India Working paper http://ssrn.com/abstract=992529 Bertrand, Marianne, Mehta, Paras, Mullainathan, Sendhil, 2002 Ferreting out tunneling: an application to Indian business groups Quarterly...

Ngày tải lên: 02/01/2015, 17:33

... certain starting point That is to say she/he needs to rely on a language as a base then compare the other language from certain parameters established In this case, the two languages involved are English ... describing, classifying and defining and the four different kinds of explanation including: sequential explanation, causal explanation, factorial explanation, and theoretical explanation have been ... especially in the US as genre has in recent years become associated with a disreputably formulaic way of constructing particular texts - a kind of writing or speaking by numbers This association, as...

Ngày tải lên: 31/03/2015, 14:14

... certain starting point That is to say she/he needs to rely on a language as a base then compare the other language from certain parameters established In this case, the two languages involved are English ... describing, classifying and defining and the four different kinds of explanation including: sequential explanation, causal explanation, factorial explanation, and theoretical explanation have been ... especially in the US as genre has in recent years become associated with a disreputably formulaic way of constructing particular texts - a kind of writing or speaking by numbers This association, as...

Ngày tải lên: 31/03/2015, 14:34