ecotoxicology a comprehensive treatment—conclusion

... DIMEGLUMINE GADOPENTETATE, GADOBUTROL, GADOXETIC ACID DISODIUM, AND GADOFOSVESET TRISODIUM WITH DAPHNIA MAGNA The crustacean Daphnia magna represents the primary feeder of an aquatic ecosystem ... detergents and are required by the European Reserach Area (EU ERA) guideline to assess the degradation of a human pharmaceutical The test compounds dimeglumine gadopentetate, gadoxetic acid disodium, and ... dimeglumine gadopentetate and sodium acetate are depicted in Figure 4.3 Degradation of the test compound started between day 15 and day 21, and degradation values of approximately 40% were reached after...

Ngày tải lên: 18/06/2014, 16:20

... with an average diameter of 90 nm The average hydrodynamic diameter of the carbon-coated nanoparticles measured by a DLS particle size analyzer was about 200 nm (Figure 2) This diameter was larger ... materials have attracted a great deal of attention in the development of biotechnology and medicine [1-3] Among these nanostructured materials, carbon-coated metal oxide nanoparticles such as ... precipitated These magnetic particles were separated by a magnet and were washed out by methanol, acetone, and DI [deionized] water The collected nanoparticles were dried in a vacuum oven to obtain a...

Ngày tải lên: 20/06/2014, 23:20

... that shuttle contrast agents into targeted cells [2] A feasible way of enabling active targeting is to employ a nanoparticulate structure, which can serve as a scaffold for targeting ligands and ... such as liposomes and dendrimers In general, nanoparticulates offer large surface area, which can serve as a scaffold for targeting ligands and magnetic labels [3] Therefore, much attention has ... to the animal care legislation and approved by Institutional Animal Care and Use Committee (IACUC), National University of Singapore Male Sprague Dawley rats (200~250 g) were used An amount of...

Ngày tải lên: 06/10/2015, 21:15

... inpatient and outpatient facilities at the Hamamatsu University Hospital and associated hospitals in the city of Hamamatsu, Japan In all, 18 patients with onset equal to or below 16 years participated ... the American Academy of Child and Adolescent Psychiatry Washington, DC: AACAP; 1997:172-173 Office of Population Censuses and Surveys: Standard occupational classification, Social classifications ... Vidal C, Giedd JN, Gochman P, Blumenthal J, Nicolson R, Toga AW, Rapoport JL: Mapping adolescent brain change reveals dynamic wave of accelerated gray matter loss in very Proc Natl Acad Sci USA...

Ngày tải lên: 08/08/2014, 23:21

... biomarker assays Once the biomarker assay data and MRI data were merged, 137 subjects had complete data (both complete biomarker and longitudinal MRI data) available for analysis These participants ... cartilage score at 30 months from that at baseline After completion of the assays, 153 par- Available online http://arthritis-research.com/content/9/5/R108 ticipants had data available for all ... monoclonal antibodies are directed against separate antigenic determinants on the COMP molecule (intra-assay and interassay variations of less than 5% and a detection limit of less than 0.1 U/L)...

Ngày tải lên: 09/08/2014, 10:21

... ideal continuous k-space data MNC(kx,ky) non-Cartesian sampled k-space data MC(kx,ky) Cartesian sampled k-space data P polarization pR calculated pH based on Henderson-Hasselbach equation Psa ... image space as a result of radial sampling 3.12 (A) Scheme of a 2D gridding procedure The data samples lie on an arbitrary trajectory through k-space (dashed line) The sampled data points are ... superparamagnetic iron-oxide nanoparticles STAT signal transducers and activators of transcription STZ streptozotocin T1 longitudinal relaxation time T2 transverse relaxation time TAT transactivator...

Ngày tải lên: 11/09/2015, 10:01

... Goldberg V, Caplan A: A semiquantative scale for histologic grading of articular cartilage repair Acta Anat 1992, 143:335-340 32 Wakitani S, Goto T, Pineda S, Young RG, Mansour JM, Caplan AI, Goldberg ... normal or near normal, = abnormal Vascularisation and mineralisation are both included as negative features, because they are not present in normal articular cartilage, but there is concern that ... intervals of 76 and 110 days On MRI, the thickness of the graft cartilage appeared the same as that of the adjacent cartilage in 68% of patients The surface of the articular cartilage was smooth...

Ngày tải lên: 09/08/2014, 01:21

... Arbab AS, Wilson BL, Ashari P, Jordan EK, Lewis BK, Frank JA: A model of lysosomal metabolism of dextran coated superparamagnetic iron oxide (SPIO) nanoparticles: implications for cellular magnetic ... were separated by ultracentrifugation at 30000 rpm (Optima LE-80K, Beckman, Palo Alta, CA) using a fixed angle rotor (50.2 Ti) for 30 at 10°C The supernatant was discarded, and the sediment was redispersed ... as a novel nanomatrix and ceramic modification Carbo Polym 2007, 69:467-477 Kim DK, Mikhaylova M, Zhang Y, Muhammed M: Protective coating of superparamagnetic iron oxide nanoparticles Chem Mater...

Ngày tải lên: 11/08/2014, 00:22

... because no intramural haematoma was visible via a standard neck MRI He was discharged after making a good recovery at 12 days after he was admitted He was started on aspirin, dipyridamole and ... normocapnia and hypercapnia (during inhalation of 10% CO2) Using these images, CVR maps are generated, where an increase in BOLD signal is used as a marker of cerebral vasodilatory capacity Our patient ... his arm, leg and face, and a right homonymous hemianopia His vascular risk factors included a 25 pack-year smoking history and a previous myocardial infarction An initial computed tomography...

Ngày tải lên: 11/08/2014, 11:23

... signal intensity on turbo FLAIR MR images Radiology 2003, 227:538-541 34 Kawahara H, Takeda Y, Tanaka A, Nagano O, Katayama H, Hirakawa M, Hiraki Y: Does diffusion-weighted magnetic resonance imaging ... clinical outcome between the two groups Quantitative analysis of the ADC values ROI analysis The ADC value was measured in 22 patients: had a favourable outcome, and 14 had an unfavourable outcome ... with clinical outcomes in neonates with perinatal asphyxia [13] and patients after cardiac arrest [14,15] DWI abnormalities in large areas including the cerebral cortex, basal ganglia, and cerebellum...

Ngày tải lên: 13/08/2014, 20:21

... (yellow arrows) was induced at Day -2 and cellular transplantation took place on Day by contralateral intracerebral (green arrows) or systemic injection (IV) (a) An area of hypointensity appeared ... successfully for many years to treat leukaemia and other haematological malignancies, and clinical trials using autologous and even allogeneic stem cell transplantation therapies are being run concurrently ... that can mature into late endosome and lysozome (Perry, 1979) 87  Figure 11 TEM of Caveolae invaginations Caveolae are flasked-shaped plasma invaginations After internalization,...

Ngày tải lên: 14/09/2015, 08:49

... Sulzbach, Germany) — while Pasquale et al [12] tested the ParaGard® CuT38 0A (Ortho-McNeil Pharmaceutical Corp., Raritan, NJ, USA) More recently, Zieman and Kanal [13] reassessed the usage safety ... susceptibility are called superparamagnetic or ferromagnetic) In the presence of discordant (antiparallel) magnetization, the substances are classified as exhibiting negative magnetic susceptibility and are ... Raritan, NJ, USA) and a Cu-IUD (Cu-7; Searle Pharmaceuticals, Chicago, IL, USA) in order to assess the possible occurrences of movement, IUD temperature increase and generation of image artifacts...

Ngày tải lên: 13/02/2014, 07:20

... Saccade Saccade Saccade Saccade Saccade Saccade Pro-anti saccade Pro-anti saccade Pro-anti saccade Pro-anti saccade Corrective saccade SPEM, saccade SPEM, saccade SPEM, saccade SPEM SPEM SPEM ... http://dx.doi.org/10.1007/s00221-007-1077-y Hayakawa, Y., Nakajima, T., Takagi, M., Fukuhara, N & Abe, H (2002) Human cerebellar activation in relation to saccadic eye movements: a functional magnetic resonance imaging study., Ophthalmologica ... Functional Magnetic Resonance Imaging – Advanced Neuroimaging Applications section, segmentation algorithms are illustrated to provide brain surface-based analysis, automated anatomical labeling...

Ngày tải lên: 19/02/2014, 23:20

... metastasis in colorectal cancer Cancer Lett 1995, 91:145-149 Logunov DY, Zubkova OV, Karyagina-Zhulina AS, Shuvalova EA, Karpov AP, Shmarov MM, Tutykhina IL, Alyapkina YS, Grezina NM, Zinovieva NA, ... oncolytic adenoviruses in humans Acknowledgements We thank Prof Ramon Alemany, Neus Baxo-Puxan, Raul Gil-Hoyos and Marta Gimenez-Alejandre (Translational Research Laboratory, Institut d’Investigació ... of animals was treated in each group (A) Luciferase expression of organs was analyzed Data are presented as relative light units (RLU) after normalization for protein concentration Each bar represents...

Ngày tải lên: 18/06/2014, 16:20

... Isobe K, Nakata Y, Takaso M, Inoue M, Maruta T, Akazawa T, Ueda T, Moriya H: An analysis of chest wall and diaphragm motions in patients with idiopathic scoliosis using dynamic breathing MRI ... the carina (C), maximal inspiratory image (b) Lower level at the apical vertebra (A) , maximal inspiratory image Tangential lines are drawn to the anterior, posterior and lateral lung surfaces The ... reformatted coronal image (a) At maximal inspiratory image and (b) maximal expiratory image The diaphragmatic heights were taken as the vertical distance in between the line drawn tangent to the...

Ngày tải lên: 20/06/2014, 01:20

... hyperplane that separates two classes of data samples as farther as possible by maximizing the margin of separation between classes and the hyperplane It is originally developed as a binary classifier ... reasons One is that the images to be processed are brain MR images in which case the brain anatomy can be always used as prior knowledge and also as a base to select reasonably good training samples ... analysis In order to address this issue, another approach views MR images as an image sequence that can be treated as multispectral images [10–12] where each band image can be considered as an...

Ngày tải lên: 21/06/2014, 22:20

... 44 Bifurcation of trachea Right pulmonary artery Ligamenta flava Thoracic vertebra Left atrium Intervertebral space Coronary sinus Descending aorta Diaphragm (lumbar part) Paratracheal lymph ... lymph nodes Paratracheal lymph nodes Anterior mediastinal lymph nodes Paraesophageal lymph nodes Parasternal lymph nodes Paravertebral lymph nodes Moeller, Sectional Anatomy © 2007 Thieme All rights ... of scapula Superficial axillary lymph nodes Interpectoral lymph nodes Prevertebral lymph nodes Paratracheal lymph nodes Anterior mediastinal lymph nodes Parasternal lymph nodes Paraesophageal lymph...

Ngày tải lên: 29/06/2014, 09:21

... Intercostal artery Bile duct Hepatic portal vein (left branch) Stomach Hepatic portal vein Pancreas Diaphragm (lumbar part) Nerve root Renal artery and vein Inferior vena cava Erector spinae muscle ... Rectus abdominis muscle Psoas major muscle Ovarian vein Lumbosacral plexus Ureter Heart Lung 31 20 Rib 21 Cardiac part of stomach (cardiac orifice) 22 Diaphragm (lumbar part) 23 Splenic artery and ... Angiography 10 11 Abdominal aorta Right renal artery Inferior capsular branch of the renal artery Aortic bifurcation Common right iliac artery 10 11 Splenic artery Left renal artery Lumbar arteries Common...

Ngày tải lên: 29/06/2014, 09:21