ecm cytokines and growth factors in cns injury

unsicker - cell signaling and growth factors in development

unsicker - cell signaling and growth factors in development

... Superfamily and Neuropeptides 44 Oocytes 45 Growth Factors for Fetal Oocytes 45 Growth Factors for Growing and Mature Oocytes 46 Growth Factors in the Initiation of Follicle and Oocyte Growth 48 ... 7.3.5 Interactions between FGF and Retinoid Signaling 199 Krox20 and Kreisler Regulate Paralogous Groups and in the Vertebrate Hindbrain 201 Establishing the Hox Code in the Vertebrate Hindbrain: ... Transforming Growth Factors- a, Neuregulins and Epidermal Growth Factors 246 Ligands, Receptors and Expression during Neurogenesis 247 Function during Neurogenesis 247 Transforming Growth Factors- b...

Ngày tải lên: 03/04/2014, 12:05

1,1K 320 0
Tài liệu HEMATOPOIETIC GROWTH FACTORS IN ONCOLOGY BASIC SCIENCE AND CLINICAL THERAPEUTICS pptx

Tài liệu HEMATOPOIETIC GROWTH FACTORS IN ONCOLOGY BASIC SCIENCE AND CLINICAL THERAPEUTICS pptx

... these cytokines in vivo in murine models of leukemia and myeloproliferative disease based on BCR-ABL and several leukemogenic TEL-tyrosine kinase fusion oncoproteins (84,85); in all models, combined ... have delineated the potential beneficial activities of HGF in current clinical use, including studies exploring dosing and scheduling parameters that inform the clinical use of these agents in the ... was observed during L monocytogenes infection (45) GM-CSF deficiency attenuated in ammation in a murine model of arthritis induced by BSA and IL-1 injection (56) and also in murine models of immune-mediated...

Ngày tải lên: 16/02/2014, 07:20

489 481 0
Báo cáo y học: "Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers" doc

Báo cáo y học: "Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers" doc

... Organization standards for any human and murine cytokine, including murine endostatin The minimum detectable concentration of endostatin was less than 12 pg/ml, and the interassay and intra-assay ... hypoxia inducible factor [31] In addition, a variety of cytokines (e.g interleukin-1, transforming growth factor beta and platelet-derived growth factor) known to be upregulated in SSc induce ... al inducers and inhibitors are balanced and angiogenesis does not occur in healthy tissues In a hypoxic environment and in inflammatory states such as rheumatoid arthritis, angiogenic growth factors...

Ngày tải lên: 09/08/2014, 06:22

10 432 0
Báo cáo y học: "Growth factors in lung development and disease: friends or foe?" pptx

Báo cáo y học: "Growth factors in lung development and disease: friends or foe?" pptx

... Research Vol No Desai and Cardoso Figure Growth factors in development and disease Major roles of selected growth factors in embryonic and postnatal lung development (left) and their potential ... endothelial growth factor architecture of the airspaces (see Fig 1) An analysis of their role in development and disease follows Growth factors in development Growth factors are involved in virtually ... instillation of FGF7 in rats ameliorates radiation-induced and bleomycin-induced lung injury, reduces alveolar damage by hydrochloric acid instillation, and decreases hyperoxia-induced mortality...

Ngày tải lên: 12/08/2014, 18:20

4 256 0
Báo cáo y học: "Prevalence of Overactive Bladder, its Under-Diagnosis, and Risk Factors in a Male Urologic Veterans Population"

Báo cáo y học: "Prevalence of Overactive Bladder, its Under-Diagnosis, and Risk Factors in a Male Urologic Veterans Population"

... possible effective and fast screening tool Our study also examined the risk factors for OAB in men We found that OAB increased with age: 49% in men aged 40-49 years to 79% in men aged 70-79 years ... Schulz J and Corcos J A population-based study of urinary symptoms and incontinence: the Canadian Urinary Bladder Survey BJU Int 2008; 101:52 Milsom I, Abrams P, Cardozo L, Roberts RG, Throff J and ... 48:622 Irwin D, Milsom I, Hunskaar S, Reilly K, Kopp Z, Herschorn S, et al Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries:...

Ngày tải lên: 25/10/2012, 11:35

4 522 0
Nutritional Status and Associated Factors in Institutionalized Elderly docx

Nutritional Status and Associated Factors in Institutionalized Elderly docx

... performance in the ability to perform activities of daily living and greater dependence on care, including meals and purchase of food [19] The results of the Health, Welfare and Aging in Latin America and ... polyunsaturated and monounsaturated fatty acids was shown to be inadequate in almost all individuals There was a significantly insufficient intake of potassium (100%), zinc (82.7%) and niacin (65.4%) in the ... portions of food in the dining room Immediately following the meal, the difference between what had been served and what remained was calculated in household measures, thus providing the intake This...

Ngày tải lên: 05/03/2014, 21:20

5 552 0
The Fraction of Cancer Attributable to Lifestyle and Environmental Factors in the UK in 2010 docx

The Fraction of Cancer Attributable to Lifestyle and Environmental Factors in the UK in 2010 docx

... www.bjcancer.com and comments; Colette Pryor for collating incidence data and Katrina Brown for invaluable support in preparing the report for submission Funding This work was undertaken by DM Parkin with financial ... and permissions For detailed information on reprint and permission requests, including instructions for obtaining these online, please visit http://www.nature.com/reprints Alternatively, for permissions, ... environmental factors in the UK in 2010: Summary and conclusions DM Parkin, L Boyd and LC Walker Cancers attributable to dietary factors in the UK in 2010: III Low consumption of fibre DM Parkin and L Boyd...

Ngày tải lên: 22/03/2014, 16:21

92 563 0
situation of hiv, hbv, hcv infection and associated factors in some high risk populations in hanoi, 2008-2010

situation of hiv, hbv, hcv infection and associated factors in some high risk populations in hanoi, 2008-2010

... Several influencing factors increase the transmission of HIV, HBV, HCV among IDUs, FSWs, HDPs and MTPs in Hanoi, 2008-2010: + Risks for HIV, HBV, HCV infection among IDUs and FSWs was drug injecting ... routine and sentinel surveillance with HIV surveillance for IDUs and FSWs associated with injecting drug to contribute making effective prevention and treatment for HIV, HBV, HCV infections To increase ... HBV/HCV co-infection was significantly upward tendency in duration of drug injecting - The rate of HIV/HBV co-infection also was increased in duration of drug injecting The highest rate of infection...

Ngày tải lên: 25/07/2014, 14:07

14 298 0
Báo cáo y học: "Risk and resiliency factors in posttraumatic stress disorder" pptx

Báo cáo y học: "Risk and resiliency factors in posttraumatic stress disorder" pptx

... risk factors that make an individual vulnerable towards developing a disorder [8] Risk factors can be divided into two main categories: severity and type of traumatic event, and predisposing personal ... predictors of PTSD Coping Factors Coping has been defined as the processes that individuals use to modify adverse aspects of their environment as well as to minimize internal threat induced by stress ... with and without PTSD had similar frequencies for receiving physical injuries as a result of their trauma, having to be hospitalized due to the event, and witnessing the death or severe injury...

Ngày tải lên: 08/08/2014, 20:23

9 365 0
báo cáo khoa học: "Gastrointestinal stromal tumors: correlation between symptoms at presentation, tumor location and prognostic factors in 47 consecutive patients" pot

báo cáo khoa học: "Gastrointestinal stromal tumors: correlation between symptoms at presentation, tumor location and prognostic factors in 47 consecutive patients" pot

... considered as indications for adjuvant therapy Histological processing was obtained with formalin fixation followed by paraffin inclusion, μm sectioning, and staining with hematoxylin and eosin Morphologic ... 50-70% in the stomach, 25-30% in the small intestine, 5-10% in the colon-rectum, < 5% in the esophagus, the remaining may arise within the omentum or within the peritonel layers (Extra-Gastro-intestinal ... common clinical presentation of these tumors is gastrointestinal bleeding, otherwise they may cause intestinal obstruction, abdominal pain, a palpable mass, or can be incidentally detected during...

Ngày tải lên: 09/08/2014, 01:24

10 311 0
Báo cáo y học: "Suicide attempts and related factors in patients admitted to a general hospital: a ten-year crosssectional study (1997-2007)" pot

Báo cáo y học: "Suicide attempts and related factors in patients admitted to a general hospital: a ten-year crosssectional study (1997-2007)" pot

... screening tools for identifying suicide risk in the primary care setting, including tools for identifying those at high risk, physicians should remain alert to the possibility of suicide in high-risk ... and behavior in adults In UpToDate Edited by: Solomon D 2010 Haukka J, Suominen K, Partonen T, Lönnqvist J: Determinants and outcomes of serious attempted suicide: a nationwide study in Finland, ... suicide attempts was also identified in a nationwide study in Finland [9], and in a prospective study [17] in which the authors found that the strongest single factor for suicide is prior history...

Ngày tải lên: 11/08/2014, 15:22

10 481 0
Báo cáo y học: " Progression of pulmonary hyperinflation and trapped gas associated with genetic and environmental factors in children with cystic fibrosis" ppsx

Báo cáo y học: " Progression of pulmonary hyperinflation and trapped gas associated with genetic and environmental factors in children with cystic fibrosis" ppsx

... obtained at each follow-up visit and cultured for various bacterial species including H influenzae, S aureus and P aeruginosa [46] Sampling, transport, culture and identification of strains from ... hyperinflation and gas trapping and deterioration of lung function in CF are presented here using longitudinal data Previous investigations have demonstrated that pulmonary hyperinflation influences ... of airway function and growth in infants and young children [25] Children with CF and better initial FEV1 have a slower rate of decline in lung function than those in whom initial FEV1 was already...

Ngày tải lên: 12/08/2014, 16:20

15 385 0
Báo cáo y học: " Growth factors in idiopathic pulmonary fibrosis: relative roles" ppt

Báo cáo y học: " Growth factors in idiopathic pulmonary fibrosis: relative roles" ppt

... prostaglandins including prostaglandin E2 (PGE2) and 6-keto-prostaglandin F1α (PGF1α) Prostaglandins exert negative feedback control of AEC TNF-α expression and autocrine inhibition, through raised intracellular ... appears to slow progression of IPF when administered to patients [15] Insulin-like growth factor-1 and insulin-like growth factor-binding proteins Insulin-like growth factor-1 (IGF-1) stimulates proliferation ... wound-healing responses to lung injury is IPF Growth factors have predominantly been described in fibroblasts, which are recognised key players in wound healing It is becoming increasingly apparent,...

Ngày tải lên: 12/08/2014, 18:20

9 282 0
Báo cáo y học: " Interactions between genes and environmental factors in asthma and atopy: new developments" pps

Báo cáo y học: " Interactions between genes and environmental factors in asthma and atopy: new developments" pps

... polymorphisms in candidate genes for asthma/atopy have been identified Linkage and candidate gene studies in asthma and atopy Linkage studies Results from linkage studies (genome-wide searches and candidate ... of inconsistent findings, it is intriguing that chromosomal regions linked to asthma have also shown evidence for linkage to other inflammatory and autoimmune diseases (such as psoriasis, inflammatory ... other genes involved in the allergic inflammation (e.g IL-4Rα [21], β2AR [24]) We can therefore speculate that inconsistent findings in the genetic studies of asthma and atopy summarized in this...

Ngày tải lên: 12/08/2014, 18:20

15 380 0
Báo cáo khoa học: "Outcome and prognostic factors in critically ill patients with systemic lupus erythematosus: a retrospective study" pdf

Báo cáo khoa học: "Outcome and prognostic factors in critically ill patients with systemic lupus erythematosus: a retrospective study" pdf

... to the ICU Gastrointestinal bleeding, intracranial haemorrhage and septic shock during the ICU stay were associated with a greater risk of death, indicating that clinical course and medical care ... morbidity and acute physiological condition – play key roles in influencing the prognosis of SLE patients in the ICU 0.01 Concurrent septic shock in the ICU The incidence of gastrointestinal haemorrhage ... intracranial haemorrhage, including brainstem haemorrhage, subarachnoid haemorrhage and frontal lobe haemorrhage, to be a factor that increases the risk of dying Acute stroke (infarction or intracranial...

Ngày tải lên: 12/08/2014, 22:21

7 422 0
Báo cáo sinh học: " Mapping of quantitative trait loci for flesh colour and growth traits in Atlantic salmon (Salmo salar)" ppt

Báo cáo sinh học: " Mapping of quantitative trait loci for flesh colour and growth traits in Atlantic salmon (Salmo salar)" ppt

... sex-specific recombination differences observed in salmonids [18] Marker grouping and initial marker ordering was done with Joinmap 3.0 [19] A Joinmap input file was made for each mapping parent (in double ... containing information on alleles inherited from that parent only Marker grouping was performed at a minimum LOD score of 4.0 Following marker grouping, homologous linkage groups from each sire and ... dam were integrated into single sex-specific maps The data was examined for unlikely double recombinants and for inconsistencies in marker order between parents using a custom VBA program in Excel...

Ngày tải lên: 14/08/2014, 13:21

14 325 0
the value of switching and growth options in foreign direct investmentl

the value of switching and growth options in foreign direct investmentl

... findings points to the need for a more fine-grained investigation of the real options perspective in relation to foreign direct investments In uncovering the reason for these divergent findings, ... counteracting effects in determining the optimal timing of learning Martzoukous and Trigeorgis (2001) attempt to find the appropriate timing of learning In the presence of costly learning, there ... 1981) In making the point that real options logic does not hold for endogenous uncertainty, Cuypers and Martin (2006) noted since only investing will reveal the relevant information under uncertainty...

Ngày tải lên: 02/11/2014, 00:48

137 208 0
Genetic predisposition and dietary factors in relation to adiponectin and insulin resistance

Genetic predisposition and dietary factors in relation to adiponectin and insulin resistance

... interleukin-6 (IL-6), leptin, retinol-binding protein (RBP4) are pro-inflammatory, while adiponectin (introduced in the next chapter) has a unique anti-inflammatory and insulin sensitizing property ... highest in Asian Indians, intermediate in Malays, and lowest in Chinese CRP was higher in Asian Indians and Malays than in Chinese, and Indian women had particularly high levels of CRP Total and ... serum insulin response was represented by the insulin peak and expressed as the 19 mean value of the serum insulin concentrations determined at 4, and minutes The insulin index was defined as...

Ngày tải lên: 10/09/2015, 09:05

164 324 0
Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia

Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia

... fibroblast growth factor, transforming growth factor β, 11 and insulin like growth factor-1; (b) Cytokines: TNF-α, interleukins; (c) Hormones: prolactin and estradiol; (d) Hypoxia, and (e) Histamine ... the kinases phosphorylate erythro-sphingosine (Sphingosine), dihydrosphingosine and phytosphingosine, which are key sphingolipids (Melendez, 2008) In adult mouse, SphK1 is present abundantly in ... A Ling and S T Dheen*, "Sphingosine kinase signaling mediates the activation of microglia by inducing proinflammatory cytokines " 2008 Neuroscience Meeting Planner (2008): 356.13/BB28 Online:...

Ngày tải lên: 16/10/2015, 15:38

109 222 0
Stabilization, Adjustment and Growth Prospects in Transition Economies

Stabilization, Adjustment and Growth Prospects in Transition Economies

... constraints), it permitted new and expanding sectors to obtain resources This in turn supported growth in new new and productive sectors and moderated the decline in GDP Hence, reforming transition ... more than 1000 percent Starting in 1992 growth was turned positive in Poland and by 1994 all advanced reformers were growing strongly which continued in 1995 and preliminary estimates of output ... As shown in table 3, this was realized and rapidly reforming economies recording the largest increases as a percentage in their GDPs In fact, given the decline in the shares of industry and agriculture,...

Ngày tải lên: 21/04/2016, 07:25

53 287 0
w