... The time -of- flight 20 fly faster (TOF) of the ion, before it is detected by an electrode, 50 is a measure of the mass to charge (m/z) value of the 80 ion The ion spectra can be analysed by computerassisted ... the development of variations of the traditional 2D-gel approach, and the application of these has resulted in the identification of potential new biomarkers for early detection of disease Differential ... chance of 5-year survival Implementation of a highly sensitive and specific test for the early detection of cancer could significantly increase the number of ovarian cancer cases detected at early...
Ngày tải lên: 15/02/2014, 05:20
... Permanente of Southern California, Pasadena, CA TIM BYERS, M.D., M.P.H., Professor of Epidemiology, University of Colorado, Denver, CO VIVIAN WAI-MEI CHEN, Ph.D., Chief & Professor of Epidemiology, ... regardless of when their tumors are found, early detection will be looked upon as the best hope for reducing the burden of this disease The hope is that early detection of breast cancer by screening ... women regardless of when their tumor is found, early detection will be looked upon as the best hope for reducing the heavy toll of this disease The early detection of cervical cancer by screening...
Ngày tải lên: 05/03/2014, 12:20
Serum Biomarkers for Early Detection of Gynecologic Cancers ppt
... Sensitivity early 83% early, M early, all 95% 89% early, S early, E 94% 98% Specificity early 94% early, M early, all 92% 97% early, S early, E 94% 98% 95% 99% The sensitivity and specificity of each ... 125, ApoA-I, TF, and TTR for the early detection of ovarian cancer [83] This model provided a sensitivity of 89% and a specificity of 97% for the detection of early stage ovarian cancer Furthermore, ... 82% Specificity 100% Early Late 88% 86% 86% Shown here is the sensitivity and specificity of each serum biomarker panel used in the detection of endometrial cancer; Early: early- stage cases; Late:...
Ngày tải lên: 22/03/2014, 11:20
STUDY ON EPIDEMIOLOGICAL FEATURES, APPLICATION OF DIAGNOSTIC KIT FOR DETECTION OF TRYPANOSOMIASIS CAUSED BY TRYPANOSOMA EVANSI IN CATTLE AND BUFFALOES IN A FEW NORTHERN MOUNTAINOUS PROVINCES AND RECOMMENDATION FOR PREVENTIVE AND TREATMENT MEASURES
... Number of Number of Number Number of Number Number of Number Results r of mice cleared mice cleared of of mice mice cleared of of mice mice cleared of of mice of monitoring mice of trypanosomes ... Number of Number Number of Number Number of Number Results r of mice cleared mice cleared of of mice mice cleared of of mice mice cleared of of mice of monitoring mice of trypanosomes killed trypanosomes ... Number of Number Number of Number Number of Number Results r of mice cleared mice cleared of of mice mice cleared of of mice mice cleared of of mice of monitoring mice of trypanosomes killed trypanosomes...
Ngày tải lên: 28/04/2014, 13:08
Báo cáo hóa học: "Early detection of urothelial premalignant lesions using hexaminolevulinate fluorescence cystoscopy in high risk patients" potx
... WM: The accuracy of urinary cytology in daily practice Cancer 1999, 87:118-128 Kriegmair M, Knuchel R, Stepp H, Hofstaedter F, Hofstetter A: Detection of early bladder cancer by 5-aminolevulinic ... recommended in the early follow-up of high risk patients Author details Department of Urology, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy 2Department of Clinical Pathology, ... patients and if the improvement in the rate of detection of flat lesions in the follow-up may improve the use of additional treatment and the prognosis of these patients Conclusions Photodynamic...
Ngày tải lên: 18/06/2014, 16:20
Chapter 078. Prevention and Early Detection of Cancer (Part 1) pps
... tobacco-related The degree of smoke exposure, meaning the number of cigarettes smoked per day as well as the level of inhalation of cigarette smoke, is correlated with risk of lung cancer mortality ... pediatric issue Over 80% of adult American smokers began smoking before the age of 18 Nearly 20% of Americans aged 12– 18 have smoked a cigarette in the past month Counseling of adolescents and young ... identification and manipulation of the genetic, biologic, and environmental factors in the causal pathway of cancer Education and Healthful Habits Public education on the avoidance of identified risk factors...
Ngày tải lên: 07/07/2014, 01:20
Chapter 078. Prevention and Early Detection of Cancer (Part 2) ppt
... risk of melanoma in adulthood Reduction of sun exposure through use of protective clothing and changing patterns of outdoor activities can reduce skin cancer risk Sunscreens decrease the risk of ... the risk of breast and prostate cancer by absorbing and inactivating dietary estrogenic and androgenic cancer promoters However, two large prospective cohort studies of >100,000 health professionals ... in 9.8% of women in the low-fat diet group compared to 12.4% of women on the standard diet In observational studies, dietary fiber lowers the risk of colonic polyps and invasive cancer of the...
Ngày tải lên: 07/07/2014, 01:20
Chapter 078. Prevention and Early Detection of Cancer (Part 3) doc
... gas Cancer of the lung, head and neck, nasal sinuses Nickel dust Cancer of the lung, nasal sinuses Phenacetin Cancer of the renal pelvis and bladder Polycyclic hydrocarbons Cancer of the lung, ... Androgens Prostate cancer Aromatic amines (dyes) Bladder cancer Arsenic Cancer of the lung, skin Asbestos Cancer of the lung, pleura, peritoneum Benzene Acute myelocytic leukemia Chromium Lung ... Epstein-Barr virus Burkitt's lymphoma, nasal T cell lymphoma Estrogens Cancer of the endometrium, liver, breast Ethyl alcohol Cancer of the liver, esophagus, head and neck Helicobacter pylori Gastric cancer,...
Ngày tải lên: 07/07/2014, 01:20
Chapter 078. Prevention and Early Detection of Cancer (Part 4) pdf
... study suggested that statins decrease the incidence of colorectal cancer However, a meta -analysis of statin use showed no protective effect of statins on overall cancer incidence or death ... change in the risk of lung cancer for those taking β-carotene; fewer of its participants were smokers than those in the ATBC and CARET studies Chemoprevention of Colon Cancer Many of the current ... reduced the recurrence of colorectal polyps in patients with familial adenomatous polyposis The effect on colon cancer occurrence is unknown Trials for prevention of sporadic colorectal cancers with...
Ngày tải lên: 07/07/2014, 01:20
Chapter 078. Prevention and Early Detection of Cancer (Part 5) pdf
... could prevent >70% of the cervical cancers worldwide Surgical Prevention of Cancer Some organs in some individuals are at such high risk of developing cancer that surgical removal of the organ at ... prophylactic mastectomy could reduce risk of breast cancer by 90% The effect of the procedure on mortality is unknown Observational studies are prone to a variety of biases associated with the choice ... Trial randomly assigned men ≥55 years at average risk of prostate cancer to finasteride or placebo After years of therapy, the incidence of prostate cancer was 18.4% in the finasteride arm and...
Ngày tải lên: 07/07/2014, 01:20
Chapter 078. Prevention and Early Detection of Cancer (Part 6) ppsx
... specificity of a test are relatively independent of the underlying prevalence (or risk) of the disease in the population screened, but the predictive values depend strongly on the prevalence of the ... proportion of persons with the disease testing positive in the screen (i.e., the ability of the test to detect disease when it is present) Specificity, or 1-false positive rate, is the proportion of ... ability to predict the development of a particular cancer may some day present therapeutic options as well as ethical dilemmas It may eventually allow for early intervention to prevent a cancer...
Ngày tải lên: 07/07/2014, 01:20
Chapter 078. Prevention and Early Detection of Cancer (Part 7) pps
... favorable An extreme form of length bias sampling is termed overdiagnosis, the detection of "pseudo disease." The reservoir of some undetected slow-growing tumors is large Many of these tumors fulfill ... treatment of cancers that would never have caused medical problems can lead to the harm of unnecessary treatment and give patients the anxiety of a cancer diagnosis The psychosocial impact of cancer ... the entire population Assessment of Screening Tests Good clinical trial design can offset some biases of screening and demonstrate the relative risks and benefits of a screening test A randomized,...
Ngày tải lên: 07/07/2014, 01:20
Chapter 078. Prevention and Early Detection of Cancer (Part 8) potx
... uterine with Fair evidence to cervix, include in examination beginning of sexually active years after first women intercourse by age Yearly or 21 for standard Pap; every years with liquid test Pelvic ... Periodic Poor evidence to include or exclude against a Summary of the screening procedures recommended for the general population by U.S Preventive Services Task Force (USPSTF), the American Cancer ... Insufficient evidence as exclude F: 20–40, F: 50–69, every a every years; 1–2 years stand-alone >40, yearly without mammography Mammography F: 40–75, F: ≥40, every 1–2 years every year F: 50–69, every...
Ngày tải lên: 07/07/2014, 01:20
Chapter 078. Prevention and Early Detection of Cancer (Part 9) potx
... initiation of screening Nearly half of women aged 40–49 screened annually will have false-positive mammograms necessitating further evaluation, often including biopsy The risk of false-positive testing ... study of breast self-examination has shown it to decrease mortality; however, it is recommended as prudent by many organizations A substantial fraction of breast cancers are first detected by patients ... proportion of this benefit is due to screening after these women turned 50 is not known In randomized screening studies of women aged 50–69, the mortality decline begins about years after initiation of...
Ngày tải lên: 07/07/2014, 01:20
Chapter 078. Prevention and Early Detection of Cancer (Part 10) doc
... Prevention Trial showed that rigorous screening of low-risk men for years leads to the diagnosis of prostate cancer in >12% of patients In addition, 15% of men who had normal DRE and PSA levels after ... workup of vaginal bleeding in postmenopausal women but are not considered as screening tests in symptomatic women Skin Cancer Visual examination of all skin surfaces by the patient or by a health ... guidelines for the early detection of cancer, 2003 CA Cancer J Clin 53: 27, 2003 [PMID: 14756304] Stoutjesdijk M: Magnetic resonance imaging and mammography in women with a hereditary risk of breast cancer...
Ngày tải lên: 07/07/2014, 01:20
Báo cáo khoa học: " relationships for carbon and nitrogen during early growth of Juglans regia L. seedlings: analysis at two elevated CO concentrations 2" doc
... oak, where the allocation of 15 originated from a fertilised N soil was not altered by CO [36] In trees, the role of buffer played by the mobilisation of N reserves in case of Despite enrichment, ... Variations of the N content of both origins were also notably altered in the shoot in response to CO Accumulation of Nn decreased in the stem without notable alteration of Na at the end of experiment ... after this date A loss of about 78 % of C and of about 86 % of N was recorded on day 55 (figure 2) These changes were similar under both CO treatments The time course of C or N content was similar...
Ngày tải lên: 08/08/2014, 14:21
Báo cáo y học: "Early Detection of cytokine protein expression in mouse lung homogenates using suspension bead array" ppt
... defined by early production of TNFα followed by subsequent production of IL-1, IL-6 [8] and MIP-2 [2] The production of TNFα by macrophages and the recruitment of inflammatory cells are regulated by ... feasibility of simultaneous measurement of cytokine levels may lend to the elucidation of potential diagnostic markers of compound-induced inflammatory responses in tissues http://www.journal -inflammation. com/content/3/1/15 ... for detection of LPS (i.p administration of 0.25 mg/ml)evoked changes in levels of cytokine protein expression (at 2- and 24-hours post treatment) in mouse lung tissue homogenates Simultaneous detection...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo y học: " Early detection of Varicella-Zoster Virus (VZV)-specific T-cells before seroconversion in primary varicella infection: case report" potx
... could be explained by the early initiation of antiviral therapy at the day of rash onset We conclude that the analysis of VZV-specific CD4+ T-cells might support the rapid diagnosis of primary varicella ... more by PCR at this stage All relevant clinical and diagnostic parameters of the reported case are depicted in Figure (Fig 1) Conclusions The development of novel assays for the detection of virus-specific ... any accompanying images A copy of the written consent is available for review by the Editor-in-Chief of this journal Additional file 1: Protocol for the detection of VZV-specific T-cells: This...
Ngày tải lên: 12/08/2014, 04:20
Báo cáo y học: " Modulation of lung inflammation by vessel dilator in a mouse model of allergic asthma" doc
... inflammation in a mouse model of allergic asthma The effects of VD on airway inflammation may result from its inactivation of ERK1/2 and downregulation of NPRA expression Analysis of ERK1/2 expression ... day 28 (mice were wks of age) E D C B A @ RT-PCR detection of NPRA expression in the lung For analysis of the effect of VD on NPRA expression in vivo, three groups of mice (n = 4) were intranasally ... synthesis of nitric oxide (NO) during airway inflammation caused by induction of nitric oxide synthase-2 in several lung cell types may contribute to epithelial injury and permeability Analysis of signaling...
Ngày tải lên: 12/08/2014, 14:20