... results of biomedical researc h in our lifetime." Sir Paul Nurse, Cancer Research UK Your research papers will be: available free of charge to the entire biomedical community peer reviewed and published ... 0.19-fold E and Aβ, at least at the concentrations and proportions evaluated herein However, the equipotent activities of the apolipoprotein E 3 and ε4 isoforms suggests the possibility that either extended ... represent means ± SEM of the quotients of ThT fluorescence values obtained for each Aβ peptide in the presence of apolipoprotein E- isoform-containing conditioned medium divided by ThT values obtained...
Ngày tải lên: 19/06/2014, 22:20
... emerging markets and the restrictive relative nature of the national scales The above list is not exhaustive, and is provided for the reader’s convenience Readers are requested to review the section ... basis, and expected recoveries received by claimants in the event the insurer stops making payments or payments are interrupted, due to either the failure of the insurer or some form of regulatory ... opinion on discrete and specific areas of risk The above list is not exhaustive, and is provided for the reader’s convenience Readers are requested to review the section Understanding Credit Ratings...
Ngày tải lên: 16/02/2014, 03:20
A RIP VAN WINKLE OF THE KALAHARI AND OTHER TALES OF SOUTH-WEST AFRICA doc
... at length I entered the hollow between two of them, and found a few stunted bushes covered with red berries the size of cherries, and the like of which I had never seen before I hesitated to eat ... hoped to find to fill it, for there was no vestige of vegetation to be seen, except some tiny seeds just sprouting here and there in the hollows between the dunes I could see no other evidence of ... there in the dunes he will sleep well, that one; and die." And die he did; for the next day, refreshed and fearing the flowers little in the day time, we went back to the dune where we had left...
Ngày tải lên: 06/03/2014, 03:21
Governing Electronically E-Government and the Reconfiguration of Public Administration, Policy and Power potx
... E- government 35 early e- government literature tended to equate e with internet, seemingly in complete ignorance of other electronic ICTs used both before the internet’s invention and in parallel ... relationship between citizens and their elected representatives and the conduct of politics In this usage, the internet becomes the way in which citizens make their views known to their elected representatives, ... descriptive, denoting the deployment of internet technology for the conduct of government business As the term has become evermore widespread, a wide range of descriptive and normative meanings have been...
Ngày tải lên: 06/03/2014, 06:21
Báo cáo khoa học: The protein shuffle Sequential interactions among components of the human nucleotide excision repair pathway pdf
... complex Endonuclease XPG and the XPF–ERCC1 complex are responsible for the 3 and 5¢ DNA incisions, respectively Binding of XPG induces the release of XPC–hHR23B, whereas XPF–ERCC1 triggers excision ... cells, and are reviewed herein We will mainly discuss human NER in this review These studies reveal that NER is a dynamic process in which pivotal proteins are assembled and disassembled as needed ... define the NER process To achieve this, scientists will need to produce a detailed map of the sequential protein assembly processes that occur during damage recognition and repair Acknowledgements...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Regulation of arginase II by interferon regulatory factor 3 and the involvement of polyamines in the antiviral response potx
... were used to quantify the intracellular concentration of spermine, spermidine and putrescine as described in Experimental procedures These results are representative of two independent experiments, ... protein))1 This experiment is representative of three experiments and is expressed as mean ± SEM from triplicate determinations In the lower panels, whole-cell extracts (50 lg) were subjected ... compared with untreated cells (Fig 6, lanes and 3) However, when cells were pretreated with 31 23 IRF -3- mediated antiviral response involves spermine N Grandvaux et al A B C Fig Spermine treatment...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Interaction of the E2 and E3 components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus ppt
... stearothermophilus E2 p polypeptide chain with the dimer of a protein domain (E3 int) representing the interface domain (residues 34 3–470) of B stearothermophilus E3 The use of the engineered E3 int ... structure and the new NMR structure are probably due to the relatively low number of NOEs observed between Lys154 and Asn155 in the loop L2 The site of interaction between E3 and PSBD The chemical ... The backbone dynamics of PSBD were investigated using steady-state {1H}-15N nuclear Overhauser enhancement (NOE) experiments [32 ,33 ] Values of the {1H}-15N NOE were determined according to the...
Ngày tải lên: 16/03/2014, 18:20
IMPROVING MATERNAL MORTALITY AND OTHER ASPECTS OF WOMEN''''S HEALTH docx
... and operational reasons for the delay(s) experienced by women before receiving needed care Reasons are categorized into one of “Three Delays.” Type are delays in decisions to seek care by pregnant ... stages of dilation of the uterine cervix and delivery of the infant, respectively See FIGO Safe Motherhood and Newborn Health Committee, “Prevention and Treatment of Postpartum Hemorrhage in ... Uganda, and Zambia, for example, the 2010 estimates were that AIDS accounted for 25 percent, 31 percent, and 39 percent respectively of all indirect maternal deaths 30 The “Three Delays” Since...
Ngày tải lên: 22/03/2014, 11:20
Comparison of composition (nutrients and other substances) of organically and conventionally produced foodstuffs: a systematic review of the available literature doc
... peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed ... peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed ... reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer reviewed Not peer...
Ngày tải lên: 28/03/2014, 19:20
South American Fights and Fighters AND OTHER TALES OF ADVENTURE doc
... fared well with the expedition of Pedrarias, either, for in six weeks after they landed, over seven hundred of his unacclimated men were dead of fever and other diseases, incident to their lack of ... some degree at least of European comfort, numbered some three hundred hard-bitten soldiers The principle of the survival of the fittest had resulted in the selection of the best men from all the ... statement is not credited The fate of the gallant little gentleman is one of the mysteries of the sea Of the original eleven hundred men who sailed with the two governors there remained perhaps...
Ngày tải lên: 29/03/2014, 11:21
e-learning and the science of instruction proven guidelines for consumers and designers of multimedia learning, third edition
... testing equipment you see in the shop to take and record measurements The shop computer links the learner to actual online reference resources and the telephone offers testing hints When the learners ... Perfect? • Evidence for the amount and type of practice needed to support learning objectives • Evidence and guidelines for design of effective practice feedback • Evidence for the distribution and ... Leverage social presence to encourage deeper learning; • Design examples and practice exercises that help learners build new skills; • Use networked collaborative facilities effectively for learning;...
Ngày tải lên: 30/05/2014, 23:00
Báo cáo hóa học: " Biosynthesis of Gold Nanoparticles by Foliar Broths: Roles of Biocompounds and Other Attributes of the Extracts" pptx
... conversion, a redox reaction depending on the properties of the broths (as the reaction time, temperature and pressure were fixed) Accordingly, the relevancies between the conversion of Au(III) and each ... parameters of the foliar broths are, respectively, evaluated, the pertinence of the research is enhanced Moreover, due to its statistical characteristics the present research tends to 1 23 Nanoscale ... where Y denotes the conversion of the Au(III), X the value of any of the five parameters of each broth, Cov(X, Y) the covariance value and rxy the correlation coefficient of X and Y with a range...
Ngày tải lên: 21/06/2014, 17:20
APPLICATIONS OF MONTE CARLO METHODS IN BIOLOGY, MEDICINE AND OTHER FIELDS OF SCIENCE pps
... reached the sequence will be repeated This repetition of a sequence does not conform to the mathematical idea of an infinite sequence of independent and uniformly distributed random numbers of ... (5) the total energy E, (6) the entropy S measuring the disorderness of the system, and (7) the chemical potential of μ (i .e. , molar Gibbs free energy) An ensemble sets three (out of seven) variables ... multi-lineage priming, which requires the simultaneous expression of lineage-specific genes Prior to commitment to a certain lineage, it has been observed that these genes exhibit intermediate values of...
Ngày tải lên: 29/06/2014, 13:20
advertising, promotion and other aspects of integrated marketing communication
... with deceptive advertising and the elements that guide the determination of whether a particular advertisement is deceptive © 2010 South-Western, a part of Cengage Learning All rights reserved 21–2 ... Creates and Perpetuates Stereotypes Advertising Is Untruthful and Deceptive Advertising Is Manipulative Criticisms of Advertising Advertising Is Offensive and in Bad Taste © 2010 South-Western, ... South-Western, a part of Cengage Learning All rights reserved Information Regulation 21–20 Regulation by Federal Agencies (cont’d) Elements of the FTC’s Deception Policy Misleading Misrepresentation...
Ngày tải lên: 30/06/2014, 23:49
a study on structural and semantic components of idioms in english and vietnamese
... similarities and iv differences between English and Vietnamese idioms in terms of structural components; (2) similarities and differences between English and Vietnamese idioms in terms of semantic components; ... of Vietnamese and Vietnamese learners of English to tell one kind of idiom from the other in each language The work will also enable learners to tell when idioms in English and Vietnamese are ... documents The review of the research involves the analysis of the contents of books and articles that have been published The analysis is at a relatively simple level because the researcher pursues...
Ngày tải lên: 18/07/2014, 15:00
Báo cáo lâm nghiệp: "Simulation of wood deformation processes in drying and other types of environmental loading*" ppt
... figure The highest value of the elastic modulus is about twice as large as the lowest value ment method will not be further described here, but it can be studied elsewhere (see eg, Ottosen and Peterson, ... case where the l-direction coincides with the x-direction and &thetas; is the angle between the r-direction and the y-direction, the matrix G can be written The displacements and stresses are ... constraint of the lamella will be released, and deformation occurs The magnitude of the deformation depends on the stress in the lamella This type of test has been simulated by disconnecting elements...
Ngày tải lên: 08/08/2014, 18:21
Báo cáo khoa hoc:" A review on SNP and other types of molecular markers and their use in animal genetics" ppt
... use: the development and especially the genotyping of SNPs representing a bigger effort, due to the larger numbers needed Genetic distances between populations Genetic distances between pairs of ... hypotheses concerning the markers, and particularly the statistical independence, are needed These methodologies should therefore enable the use of dense sets of SNPs Neutrality of markers is the base ... implies the use of higher numbers and therefore raises the question of the statistical treatment of (at least partially) linked loci If independence is nevertheless assumed, power is expected to...
Ngày tải lên: 09/08/2014, 18:21
Báo cáo y học: " General and Specific Components of Depression and Anxiety in an Adolescent Population" pdf
... standard error of measurement (see figure 2) for the composite general distress factor increased the precision 11 of measurement and achieved higher precision beyond the middle of the measurement ... level between males and females were not affected by DIF Therefore in the three-factor model, the considerably higher means on the depressed mood and the worrying factor and the slightly higher ... hopelessnesssuicidal factor were more severe in females but the restlessness-fatigue factor worse in males Measurement precision of the general distress factor was higher and spanned a wider range of...
Ngày tải lên: 11/08/2014, 16:21
Báo cáo y học: " Health status in the TORCH study of COPD: treatment efficacy and other determinants of change" pps
... hypotheses about health status decline in COPD The rate of deterioration in men and women relative to loss of FEV1 appeared to be the same once gender differences in the absolute value of FEV1 were ... Older people appeared to have a faster loss of health status than younger people This was seen after other demographic and disease-related effects such as gender and baseline FEV1 had been taken ... the change over time as the left-hand panel (error bars are standard error) The right-hand plots are from a repeated measures analysis of the effects of treatment over the years of the study and...
Ngày tải lên: 12/08/2014, 13:22
Báo cáo sinh học: " Estimation of crossbreeding parameters between Large White and Meishan porcine breeds. III. Dominance and epistatic components of heterosis on reproductive traits" pptx
... Bidanel et al (1989, 1990) estimated breed additive and heterosis effects relative to the cross between the Meishan and the most widely used French breed, the Large White, for reproductive and ... relative to the cross between Meishan and Large White breeds for-reproductive traits Other parameters, including breed additive effects, were also estimated MATERIAL AND METHODS Data and experimental ... estimable when the model includes maternal effects In other instances, of some parameters have to be assumed negligible to make the model tractable example, several parameters are necessarily...
Ngày tải lên: 14/08/2014, 19:22