dynamic prognostic models for survival in pmf

... plated in media containing Geneticin to select for cell containing vector DNA After three weeks, the number of cells were determined by fixing cells and staining with dye and quantified in (H) ... common protein kinase inhibitors for an attenuation of the response in OE33 cells (data not shown) One striking observation was made using the protein kinase C (PKC) inhibitor bisindolylmaleimide ... were split and plated in media containing Geneticin to select for cell containing vector DNA After three weeks, the number of cells was determined by fixing cells and staining with dye: vector...

Ngày tải lên: 23/03/2014, 10:21

... in many instances when one includes both physical functioning and performance status in the regression models, the likelihood of finding inconsistent results can be expected In other words, in ... of survival in cancer patients Pre-treatment (baseline) quality of life data appeared to provide the most reliable information for helping clinicians to establish prognostic criteria for treating ... Baseline severe pain was predictive for a shorter overall survival QOL scores had no great importance in predicting primary clinical endpoints such as time to progression or overall survival Winer...

Ngày tải lên: 18/06/2014, 19:20

... 10 S11 [dB] Page of 25 Muscle Small Intestine Large Intestine Esophagus Stomach 30 35 40 2.2 40 Homogeneous Esophagus Stomach Small Intestine Large Intestine 30 20 2.4 2.6 10 10 2.8 Frequency ... observed in the large intestine at a distance of cm and cm because the large intestine is thin and hence the Rx moves out into a region occupied by fat C PL model 1) Homogeneous human muscle tissue In ... (Christ, in preparation) We use a child model because in children with evidence of internal bleeding and abdominal pain, correct diagnosis is a challenge and capsule endoscopy can be used for the...

Ngày tải lên: 21/06/2014, 01:20

... fragments containing the CK-18 Asp 396 neoepitope without detecting native or intact CK-18 [24,27] for assessing apoptosis, in combination with measuring total CK-18 as an indirect marker for necrosis ... subsequent inflammatory response Currently, detection of necrotic cell death involves measuring intracellular components (eg, in the liver, alanine and aspartate aminotransferases; in the heart, creatine ... participated in the design of the study and has been involved in revising the manuscript critically JS performed data acquisition, participated in the design of the study, and was involved in revising...

Ngày tải lên: 13/08/2014, 16:21

... were included in all models All the prognostic models evaluated survival as an outcome, although the timing was defined differently for all the models Further, we revealed heterogeneity in outcomes ... 12 hours from injury Further, we did not include models that required complex information such as para-clinical diagnostic tests (e.g blood sampling) or models for organ specific injuries Studies ... performance in order to inform clinical practice and future research Methods Study eligibility criteria We included studies reporting prognostic trauma models that were developed to improve clinical...

Ngày tải lên: 13/08/2014, 23:20

... are finally beaten in their cases in nature, their invincible wills are vital to emanate the adjustment for survival In a nutshell, creatures come to the world endowing with certain instincts, ... primal hunting instincts The old man employs the hunting instincts not only for the adaptation at sea, but also for his greatest kill in his life Recognized as one of the most basic instincts of ... fishing tools His images in this fight of life and death recall the battle for survival in the prehistory time, when humans’ existence mainly relies on instincts In the novel, the old man’s instinctive...

Ngày tải lên: 01/10/2014, 16:30

... oil concentration in sediment after (a) and 24 (b) hours in the NE wind Conclusion The preliminary results for the combined system of 2D, 3D hydrodynamicenvironmental models for SPM and bottom ... through the water-sediment interface So we obtain a system of three models for the oil slick, oil in water column and in the bottom sediment environments Since these models are related to each ... system of models should be based on the 3D thermohydrodynamical models for each particular environment that contains interested matter Dinh Van Uu, Ha Thanh Huong, Pham Hoang Lam 64 The marine thermo-hydrodynamical...

Ngày tải lên: 13/02/2014, 12:20

... smooth the resulting ps (e|f ), since many word pairs will be unseen for a given domain s, we are already performing an implicit form of smoothing (when computing the expected counts), since each document ... learning framework for finitestate and context-free translation models In Proceedings of ACL System Demonstrations Vladimir Eidelman 2012 Optimization strategies for online large-margin learning in ... and Bing Zhang 2009 Discriminative corpus weight estimation for machine translation In Proceedings of Emperical Methods in Natural Language Processing A K Mccallum 2002 MALLET: A Machine Learning...

Ngày tải lên: 19/02/2014, 19:20

... ”want in answer ”adenocarcinoma” in question ”was” in question ”live” in answer Q avg pos votes ”would” in answer ”answer” in question ”just” in answer ”me” in answer ”be” in answer in the” in ... 2000 Information retrieval on the web ACM Computing Surveys, 32(2) Y Liu, J Bian, and E Agichtein 2008 Predicting information seeker satisfaction in community question answering In Proceedings ... by information gain for ASP (trained for all askers) and ASP Group (trained for the group of askers with 20 to 29 questions) Conclusions We have presented preliminary results on personalizing...

Ngày tải lên: 20/02/2014, 09:20

... models for combining in- domain and 42 out-of-domain data for the purpose of bootstrapping a part-of-speech tagger for Chinese, outperforming standard methods such as EM i i i Backoff Models in ... significant differences to the baseline model are shown in boldface (p < 0.05) Set train1 train2 train3 train4 train5 Set train1 train2 train3 train4 train5 German-English baseline backoff BLEU PER BLEU ... the baseline system An analysis of the backoff system output showed that in some cases (e.g examples C and 45 Set train1 train2 train3 train4 train5 Set Set train1 train2 train3 train4 train5 German-English...

Ngày tải lên: 22/02/2014, 02:20

... Bleaching alkaliboiled product Supplying material equipment, services of producing consuming and exporting Cooking bar jelly between 200 - 210 minutes Separating product drying, packing and consuming ... and protecting environment One of typical marine economic models that has been organized and 39 Training technical staff in charge of cultivating and processing Boiling raw material in alkali ... an opportunity for surrounding communes such as Thuy Ha, Thuy Khe, Thuy Luong, Thuy Hai to form the areas specializing in vegetables and supplying raw materials for processing industry, and help...

Ngày tải lên: 22/03/2014, 12:20

... discussed in the introduction and in section 2, since CRFs and models for parsing constitute the main issue in our work, we discuss some important models here Beyond the models for parsing discussed in ... training time, which is a very good point when dealing with noisy data and big set of features 176 Models for Parsing Trees The models used in this work for parsing entity trees refer to the models ... Lexicalized models for syntactic parsing described in (Charniak, 2000; Charniak et al., 1998) and (Collins, 1997), integrate more information than what is used in equations and Considering a particular...

Ngày tải lên: 24/03/2014, 03:20

... research In addition, consumers are taking a greater role in accessing health information and pushing for better translation of research into practice Exploring the role of the public in the Clinical ... cancer; increasing the influence of breast cancer advocates in all decision making about the disease, including funding decisions for breast cancer research; and increasing collaboration in the ... professionals in clinical research across all practice settings and emerging health care systems; the timely incorporation into clinical practice of new research findings and findings on health...

Ngày tải lên: 29/03/2014, 13:20

... al., 1999) In the current paper, we use an exemplar model for computing distributional representations for word meaning in context, using the context to activate relevant exemplars Comparing representations ... are more informative and noisier, while syntax-based representations deliver sparser and less noisy information Following the hypothesis that richer, topical information is more suitable for exemplar ... significance testing W Daelemans, A van den Bosch, and J Zavrel 1999 Forgetting exceptions is harmful in language learning Machine Learning, 34(1/3):11–43 Special Issue on Natural Language Learning K Erk...

Ngày tải lên: 30/03/2014, 21:20

... chemical reaction engineering (most notably in the area of multiphase turbulent reacting flows), one is certainly justified in pointing to computational models for turbulent reacting flows as a highly ... discussed in some detail A common feature of all one-point models for turbulent reacting flows is the need for a description of molecular mixing 32 For example, all information is lost concerning the ... micromixing models not contain or use any information about the detailed flow field inside the reactor The principal weakness of RTD-based micromixing models is the lack of a firm physical basis for...

Ngày tải lên: 01/04/2014, 10:48

... gemcitabine or paclitaxel, all cell lines demonstrated an additive increase in apoptosis as demonstrated by increases in TUNEL staining (Figure 2) Similar responses were noted in all cell lines ... pressesadenocarcinoma in increases survival in model panThe sigma-2 ligand, SV119, vivo The sigma-2 ligand, SV119, combined with gemcitabine suppresses tumor growth and increases survival in model pancreatic ... by co-staining for cleaved caspase3 and the proliferation maker Ki-67 As seen in Figure 3, SV119 and gemcitabine or paclitaxel induced apoptosis in cells that were both in G0 as well as in G1 to...

Ngày tải lên: 18/06/2014, 15:20

... data interpretation PI led the writing of the manuscript; all investigators participated in its final writing and editing Competing interests The authors declare that they have no competing interests ... outcomes can be maintained up to two to three years after initiating ART in programmatic settings in countries like Cambodia Overall, the clinical and immunological outcomes in this study compared ... first-line ART in a programmatic setting in Cambodia Methods Setting In collaboration with NCHADS, MSF supported pediatric HIV programmes in two hospitals in Cambodia: the Angkor Hospital for Children,...

Ngày tải lên: 20/06/2014, 08:20

... partially linear models for longitudinal data with only -mixing and r-mixing In fact, our results with other mixing-dependent structures, such as a-mixing, *-mixing and r*-mixing, can also be obtained ... Heckman, N: Spline smoothing in a partly linear models J R Stat Soc B 48, 244–248 (1986) Speckman, P: Kernel smoothing in partial linear models J R Stat Soc B 50, 413–436 (1988) Robinson, PM: Root-n-consistent ... correlations for analyzing longitudinal data and obtained some asymptotic results based on the assumption that max 1≤i≤n m i is bounded for all n Chi and Reinsel [27] considered linear models for longitudinal...

Ngày tải lên: 20/06/2014, 22:20

... selected from China The trials sites were initially established in provinces including Ba vi, Hoa Binh and Lang son in the subtropical northern parts of Vietnam in 2007 and 2008 In 2009 an additional ... 3,73 FSI research indicates that a number of varieties are preforming well in Vietnam The key findings are included in the full report as follows: Conclusion -In Dong Hoi (Quang Binh) macca varieties, ... continue to be monitored Consistency of treatment within trials and across trials, needs to be maintained much as possible For example, intercropping and fertilizing only part of a trial block introduces...

Ngày tải lên: 21/06/2014, 06:20

... been obtained only in certain special cases All of the work done so far has been done for multivariate fds By considering the problem in the univariate domain, it is possible to gain some insight ... evaluating a polynomial in n variables over a finite field Fq is O(qn /n) The complexity of evaluating f in all of its n coordinates is thus O(qn ) and the complexity of evaluating f in all points ... points can be determined in the univariable model by solving a polynomial equation over a finite field and we give a necessary condition for a finite dynamical system to be a fixed point system Finally,...

Ngày tải lên: 22/06/2014, 19:20