dwi in head and neck regions

Regenerative Medicine Reconstruction of Tracheal and Pharyngeal Mucosal Defects in Head and Neck Surgery

Ngày tải lên : 25/10/2013, 08:20

... against infection and invading connective tissue There are still very few studies applying the methods of tissue engineering to produce tracheal replacements and to examine these in vitro and in ... this technique and bearing in mind the contraindications, more than 90% of the children can nowadays be extubated without problems In spite of the progress, in children undergoing single-step surgical ... intubation over several days as an intratracheal splinting An external splinting by metallic microplates in the surgical tracheal reconstruction was described ﬁrst time by Zalzal and Deutch in...

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Guidance on Cancer Services - Improving Outcomes in Head and Neck Cancers pot

Ngày tải lên : 22/03/2014, 16:21

... clinics at Cancer Centres (see Topic 2, Structure of services and Topic 3, Initial investigation and diagnosis) Designated head and neck cancer clinicians and clinicians in ENT, maxillofacial and ... from head and neck cancers, are discussed in Improving Outcomes in Haematological Cancers.4 There are marked regional variations in the incidence of head and neck cancers, with rates ranging from ... Association of Otorhinolaryngologists – Head and Neck Surgeons (BAOHNS) set out standards for the treatment and care of patients with head and neck cancer in 1998 These were updated in 2000 and substantially...

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Báo cáo sinh học: "Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" pot

Ngày tải lên : 18/06/2014, 22:20

... no staining (data not shown) Her2 staining was scored based on the scoring system applied to breast cancers, with scores of 0,+1, +2, +3 for increasing intensity and “continuity” of staining of ... (DakoCytomation, Carpinteria, CA) at 95°C, for 10 and 40 min, for Her3 and Her2 staining respectively To minimize non-specific staining, the section was incubated with protein block (DakoCytomation) ... membranous staining and Her3 (b, membranous and cytoplasmic staining, and c, predominant cytoplasmic staining) 400 × magnification Takikita et al Journal of Translational Medicine 2011, 9:126...

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Báo cáo sinh học: " Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas" potx

Ngày tải lên : 18/06/2014, 22:20

... strong (3+), and 26% showed no TLR4 staining (Figure 1; Table 3) TLR4 staining (all scores) showed a diffuse and fine granular cytoplasmatic pattern Distinct membrane staining was observed in some ... CW and GL participated in collection and assembly of data CP and AS participated in data analysis and interpretation CB, HSB, AB and AS wrote the manuscript All authors read and approved the final ... methods for genotyping (e.g direct sequencing, pyrosequencing or TaqMan-genotyping) were not considered Figure TLR4 immunohistochemistry in head and neck squamous cell carcinomas (A) Strong (score...

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báo cáo hóa học:" Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" doc

Ngày tải lên : 20/06/2014, 04:20

... no staining (data not shown) Her2 staining was scored based on the scoring system applied to breast cancers, with scores of 0,+1, +2, +3 for increasing intensity and “continuity” of staining of ... (DakoCytomation, Carpinteria, CA) at 95°C, for 10 and 40 min, for Her3 and Her2 staining respectively To minimize non-specific staining, the section was incubated with protein block (DakoCytomation) ... membranous staining and Her3 (b, membranous and cytoplasmic staining, and c, predominant cytoplasmic staining) 400 × magnification Takikita et al Journal of Translational Medicine 2011, 9:126...

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báo cáo hóa học:" Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas" doc

Ngày tải lên : 20/06/2014, 04:20

... strong (3+), and 26% showed no TLR4 staining (Figure 1; Table 3) TLR4 staining (all scores) showed a diffuse and fine granular cytoplasmatic pattern Distinct membrane staining was observed in some ... CW and GL participated in collection and assembly of data CP and AS participated in data analysis and interpretation CB, HSB, AB and AS wrote the manuscript All authors read and approved the final ... methods for genotyping (e.g direct sequencing, pyrosequencing or TaqMan-genotyping) were not considered Figure TLR4 immunohistochemistry in head and neck squamous cell carcinomas (A) Strong (score...

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báo cáo hóa học:" Research Article Automatic Speech Recognition Systems for the Evaluation of Voice and Speech Disorders in Head and Neck Cancer" pdf

Ngày tải lên : 21/06/2014, 20:20

... Scottish Intercollegiate Guidelines Network (SIGN), Diagnosis and management of head and neck cancer A national clinical guideline, Edinburgh (Scotland): Scottish Intercollegiate Guidelines Network ... research and clinical purpose in order to determine the global functional outcome of speech and voice after the treatment of head and neck cancer It allows quantifying the intelligibility also in severely ... −0.83 and −0.90, respectively The experts’ ratings diﬀer, compared to the automatic rating, less than one point with respect to the regression line (see Figures and 4) Discussion During and after...

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Báo cáo khoa học: "F-FDG PET/CT-based gross tumor volume definition for radiotherapy in head and neck Cancer: a correlation study between suitable uptake value threshold and tumor parameters" pdf

Ngày tải lên : 09/08/2014, 09:20

... volume delineation in head- and- neck cancer using CT and PET/CT fusion Int J Radiat Oncol Biol Phys 2006, 65:726-732 Black QC, Grills IS, Kestin LL, Wong CY, Wong JW, Martinez AA: Defining a radiotherapy ... Cummings B, Dawson L, Keller A, Kim J, Ringash J, Yu E, Hendler A, Waldron J: Intraobserver and interobserver variability in GTV delineation on FDG-PET-CT images of head and neck cancers Int ... practicable Schinagl et al compared five methods for determining the BTV using coregistered CT and FDG-PET in HNC patients [26], including visual GTV, 40% and 50% of SUVmax, an absolute SUV of 2.5, and...

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Báo cáo khoa học: "Early clinical experience with volumetric modulated arc therapy in head and neck cancer patients" ppsx

Ngày tải lên : 09/08/2014, 09:20

... modulated radiathion therapy in head and neck cancers: an update Head and Neck 2007, 29:387-400 Popovtzer A, Eisbruch A: Advances in radiation therapy of head and neck cancer Expert Rev Anticancer ... cohort, indicating that the aim of the study is to report about early experiences in head and neck with RapidArc, not focussing on specific outcome or toxicity in single subgroups It includes ... contoured by the planner and included as follow: spinal cord, brain stem, left and right parotids; larynx and uninvolved oral cavity were outlined whenever not heavily included in the target Whenever...

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Báo cáo khoa học: "Dysphagia in head and neck cancer patients following intensity modulated radiotherapy (IMRT)" pptx

Ngày tải lên : 09/08/2014, 09:20

... swallowing dysfunction after curative radiotherapy in head and neck cancer Radiotherapy and Oncology 2009, 90:189-195 Joke W, Kim De R, Duprez F, et al: Acute Normal Tissue Reactions in Head- and- Neck ... Huguenin PU, Davis JB, Kunz G, Lutolf UM, Glanzmann C: IMRT using simultaneously integrated boost (SIB) in head and neck cancer patients Radiat Oncol 2006, 1:7 Feng Y, Kim MHyungjin, et al: Intensity-Modulated ... Definitive Radiotherapy for Locally Advanced Head- and- Neck Cancer International Journal of Radiation Oncology*Biology*Physics 2009, 73:410-415 Cooper J, Fleming ID, editors, HD: Head and Neck...

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Báo cáo khoa học: "Effect of neoadjuvant chemoradiation and postoperative radiotherapy on expression of heat shock protein 70 (HSP70) in head and neck vessels" potx

Ngày tải lên : 09/08/2014, 09:20

... head and neck: interdisciplinary collaboration between head and neck surgeons in 305 cases Ann Plast Surg 1996, 36:37-43 Amarante J, Reis J, Costa-Ferreira A, Malheiro E, Silva A: Head and neck ... 2) and patients treated with neoadjuvant chemoradiation (40 Gy and cisplatin or carboplatin and paclitaxel, group3) Intima of the veins (A, * p < 0.05 vs group1 and group 2), media of the veins ... and patients treated with neoadjuvant chemoradiation (40 Gy and cisplatin or carboplatin and paclitaxel, group3) Intima of the veins (A, *; + p < 0.05 vs group1 and group 2), media of the veins...

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Báo cáo khoa học: " IMRT using simultaneously integrated boost (SIB) in head and neck cancer patients" pps

Ngày tải lên : 09/08/2014, 10:20

... Urba S, Lin A, Schipper MJ, Wolf GT: Recurrences near base of skull after IMRT for head- and- neck cancer: implications for target delineation in high neck and for parotid gland sparing Int J Radiat ... failure in patients receiving definitive and postoperative IMRT for head- and- neck cancer Int J Radiat Oncol Biol Phys 2003, 55:312-321 Puri DR, Chou W, Lee N: Intensity-modulated radiation therapy in ... function sparing in patients with head- and- neck cancers receiving intensitymodulated or three-dimensional radiation therapy: initial results Int J Radiat Oncol Biol Phys 2001, 49:907-916 Vineberg...

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Báo cáo khoa học: " The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implications" pptx

Ngày tải lên : 09/08/2014, 10:20

... Her-2, Her-3, and Her-4) These receptors are composed of an extra-cellular ligand-binding domain, a hydrophobic transmembrane segment, and an intracellular tyrosine kinase domain Binding to EGFR ... regarding overall survival [29] Tyrosine kinase inhibitors (TKI) and RT In preclinical studies, when gefitinib was combined to RT, strikingly greater than additive effects were observed in vivo ... related to the administration of an EGFR inhibitor (cetuximab) when combined to RT in head and neck cancer, confirming the promising results provided by previous phase II clinical studies Enthusiasm...

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Báo cáo khoa học: " Postoperative IMRT in head and neck cancer" pdf

Ngày tải lên : 09/08/2014, 10:21

... regularly in our joint clinics at the Department of Head and Neck Surgery or Head, Neck and Maxillofacial Surgery Further follow up visits were scheduled every – months in the first years, – monthly in ... has been defined by contouring the anatomic region of the initial primary and nodal GTV, considering the preoperative diagnostics and the clinical and histological findings The PTV1 includes the ... postoperative radiotherapy and weekly cisplatin infusion for locally advanced squamous cell carcinoma of the head and neck: preliminary report of a randomized trial Int J Radiat Oncol Biol Phys...

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báo cáo khoa học: "Uptake and fate of surface modified silica nanoparticles in head and neck squamous cell carcinoma" pps

Ngày tải lên : 11/08/2014, 00:23

... ataxia-telangiectasia-mutated (ATM) improved radiosensitivity in rodent head and neck cancer models [14-16] In addition, superior imaging in head and neck cancers resulted from the use of superparamagnetic ... Harrison PR: Profiling early head and neck cancer Nat Rev Cancer 2005, 5:127-135 Marur S, Forastiere AA: Head and neck cancer: changing epidemiology, diagnosis, and treatment Mayo Clin Proc 2008, ... recurrent/metastatic head and neck cancer Ann Oncol 21(Suppl 7):vii252-vii261 Berrino F, Gatta G: Variation in survival of patients with head and neck cancer in Europe by the site of origin of the tumours...

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báo cáo khoa học:" Early postoperative bone scintigraphy in the evaluation of microvascular bone grafts in head and neck reconstruction" ppt

Ngày tải lên : 11/08/2014, 23:22

... clinical monitoring (92% and 75% respectively) When comparing retrospectively the three monitoring schemes, i.e clinical monitoring alone, bone scans alone and clinical and bone scan monitoring together, ... For bone scintigraphy, 370 MBq 99m-Tc-oxidronate was administered intravenously Static planar scintigramms of 300 seconds were obtained starting to hours after injection in the anterior and both ... ischemia of the skin pedicle and poor scintigraphic findings (score 1), whereas two patients had revision surgery because of poor scintigraphic findings only (score 0) Thrombosis was found in all patients...

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Báo cáo y học: "Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-κB and other signal transcription factors in head and neck squamous cell carcinoma" docx

Ngày tải lên : 14/08/2014, 07:21

... which included 17 genes with p53 binding sites in cluster A and 26 genes with NF-κB binding sites in cluster B In cluster A genes with p53 binding sites, putative models containing three and four ... signal kinases on NF-kappaB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines Int J Cancer 2002, 99:538-548 Yu M, Yeh J, Van Waes C: Protein kinase ... NF-κB, and AP-1 binding sites were observed in the promoter regions of different gene clusters, suggesting their importance for the subgrouping of HNSCCs Increases in STAT3 and EGR1 binding sites...

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Báo cáo sinh học: "High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area" pdf

Ngày tải lên : 18/06/2014, 19:20

... marrow, hepatic and renal function (creatinine clearance >60 ml/min), and a computed tomography or magnetic resonance image scan of the head and neck region within three weeks prior to the initiation ... predicts cisplatinbased chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area Journal of Translational Medicine 2011 9:31 ... between DNA-dependent protein kinase and EGFR and then delayed the DNA repair [37-39] Oxaliplatin induced double-strand breaks [40] When cetuximab was combined with oxaliplatin, cetuximab reduced...

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báo cáo hóa học:" High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area" pdf

Ngày tải lên : 20/06/2014, 03:20

... marrow, hepatic and renal function (creatinine clearance >60 ml/min), and a computed tomography or magnetic resonance image scan of the head and neck region within three weeks prior to the initiation ... predicts cisplatinbased chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area Journal of Translational Medicine 2011 9:31 ... between DNA-dependent protein kinase and EGFR and then delayed the DNA repair [37-39] Oxaliplatin induced double-strand breaks [40] When cetuximab was combined with oxaliplatin, cetuximab reduced...

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Báo cáo khoa học: "Use of kilovoltage X-ray volume imaging in patient dose calculation for head-and-neck and partial brain radiation therapy" pptx

Ngày tải lên : 09/08/2014, 08:23

... by using kV CBCT and conventional CT in all cases with different tumor locations This result suggests that, for head- and- neck and brain patients, variations in the scatter effect in imaging different ... for head- and- neck patients, including nodal mass shrinkage and patient weight loss during the course of radiation therapy, can occur [28,29] For these cases, repeat CT imaging and re-planning ... Otolaryngol Head Neck Sur 2001, 125:645-8 29 Hansen EK, Bucci MK, Quivey JM, Weinberg V, Xia P: Repeat CT imaging and replanning during the course of IMRT for head- and- neck cancer Int J Radiat...

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