drugs and chemicals not shown to be harmful to the pregnant woman or fetus
Báo cáo khoa hoc:" Human MMP28 expression is unresponsive to inflammatory stimuli and does not correlate to the grade of intervertebral disc degeneration" doc
Ngày tải lên :
11/08/2014, 07:21
... been performed concerning the responsiveness of MMP28 to HDAC inhibitors Therefore, it is unknown whether most other cell types would show a behavior similar to HeLa cells (regulation) or to IVD ... evaluated according to the Thompson grading system prior to the surgical intervention (for detailed information see Table 1) [29] Informed consent was obtained from all patients according to the local ... certain proinflammatory mediators [10,25-27], which are know to regulate several MMPs [1], we hypothesized that MMP28 expression could be increased in an inflammatory context Therefore, the aim of this...
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Báo cáo khoa học: Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast docx
Ngày tải lên :
07/03/2014, 21:20
... Hsp90 drugs inhibit ATP binding [6–8], therefore progression to these later stages of the chaperone cycle It may be the progression to these later complexes that is more sensitive to Hsp90 drugs ... containing GA and RD This revealed the Dpdr5 mutant to be hypersensitive to both drugs and the Dsnq2 mutant to be slightly sensitive to RD (Fig 4B) Pdr5p is a broad-specificity ABC transporter that ... complex To seek evidence for whether this is the case, we determined if, through the expression of the T101I and A598T mutant forms of Hsp82, an Hsp90dependent process becomes more sensitive to Hsp90...
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Báo cáo y học: " Alveolar macrophages lack CCR2 expression and do not migrate to CCL2" ppt
Ngày tải lên :
11/08/2014, 08:21
... receptors The capability of one receptor to bind multiple chemokines demonstrates the complexity and redundant function of this protein family However, the expression of the receptor and the production ... human CCL2, CCL3, or fMLP was loaded into the bottom well at the appropriate concentrations, and 4.5 × 104 monocytes or alveolar macrophages were added to the upper chamber The chamber was incubated ... annealing, and 72°C for 45s for extension, according to the manufacturer's protocol The PCR products were separated on a 2% agarose gel and stained with ethidium bromide then photographed and analyzed...
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Báo cáo y học: "ntravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head"
Ngày tải lên :
25/10/2012, 11:18
... were placed on the platform, the background image was taken under the lights of an illuminator http://www.medsci.org Int J Med Sci 2011, Then, the illuminator was turned off, and the image of light ... surface of femoral head The normal femoral head was smooth and round, and the articular cartilage was transparent and glossy (A) After freezing, the femoral head was pale in the absence of normal glossiness ... fluorescent protein (GFP) labeled allogeneic MSCs were intravenously injected into nude mice and the distribution and migration of MSCs were dynamically monitored to evaluate the feasibility and...
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An investigation into the reality of teaching and learning speaking skills to the 2nd year non-major english students at pre-intermediate level of proficiency at hanoi university of industry
Ngày tải lên :
07/11/2012, 14:50
... but not encourage them to continue C Interrupt them and correct the mistake every time they make D Wait until students finish and correct all mistakes they made E Get angry and ask them to stop ... the requirements for the degree of Master of Arts is the result of my own work, except where otherwise acknowledge and that this minor thesis or any part of the same had not been submitted for ... how to the task C Give students some background knowledge about the topic D Provide some necessary vocabulary and structures related to the topic E Discuss with students to lead them to the topic...
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Tài liệu The Contribution of Sexual and Reproductive Health Services to the Fight against HIV/AIDS: A Review pptx
Ngày tải lên :
13/02/2014, 15:20
... programmes evolve and expand, they may be able to address more of these issues The first is in peer counselling and support For example, a ‘‘Mothers to mothers -to- be ’ programme in Cape Town, South ... organize and budget for such services (e.g whether it should be the MCH directorate or the HIV/AIDS control programme) and whether poor women can access HAART though private sector antenatal and delivery ... antiretroviral therapy and other medications for related HIVdisease, and training, technical assistance, laboratory support, site monitoring and other support services.96 Where STI services belong?...
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Tài liệu REPORT BY THE DIRECTOR-GENERAL ON THE UNITED NATIONS DECADE OF EDUCATION FOR SUSTAINABLE DEVELOPMENT: INTERNATIONAL IMPLEMENTATION SCHEME AND UNESCO’S CONTRIBUTION TO THE IMPLEMENTATION OF THE DECADE doc
Ngày tải lên :
21/02/2014, 17:20
... is to encourage UNECE member States to develop and incorporate ESD into their formal education systems, in all relevant subjects, and in non-formal and informal education.” The Latin America and ... be incorporated into school curricula and other educational programmes The DESD gives the educational community the incentive to incorporate the most recent information and research into programmes ... monitoring initiatives, including the EFA Global Monitoring Report, the United Nations Literacy Decade monitoring initiatives and the ongoing monitoring of the Millennium Development Goals The...
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Báo cáo khoa học: Coordination of three and four Cu(I) to the a- and b-domain of vertebrate Zn-metallothionein-1, respectively, induces significant structural changes doc
Ngày tải lên :
07/03/2014, 09:20
... Sample and measurement conditions were the same as described in Fig shown) were recorded for the ZnxCu3aMT-1 and ZnyCu4bMT-1 derivatives and used, together with the NOESY spectra, to obtain their ... incubated for >48 h before the measurement of their 1H NMR spectra The observed NOESY and TOCSY spectra (not shown) consisted of the sum of the respective spectra of the single species The spectral ... responsible for the content or functionality of any supplementary materials supplied by the authors Any queries (other than missing material) should be directed to the corresponding author for the article...
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Báo cáo khoa học: "Contradictions and Justifications: Extensions to the Textual Entailment Task" ppt
Ngày tải lên :
08/03/2014, 01:20
... assigned as the first judge for that pair and the other as the second judge The agreement between NIST and RTE annotators is shown in Table The top half of the table shows the agreement between the two-way ... since the test set already had RTE annotators’ disagreements removed But it is similar enough to support the claim that the NIST annotators agree with other annotators as often as can be expected ... the pair of scores assigned to the justification by one of the six human judges; the first number in the pair is the understandability score and the second is the correctness score for all runs Recall,...
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Báo cáo Y học: Characteristics of binding of insulin-like growth factor (IGF)-I and IGF-II analogues to the type 1 IGF receptor determined by BIAcore analysis pptx
Ngày tải lên :
08/03/2014, 22:20
... related to ability to bind to the IGF1R Previously we have expressed a recombinant form of the human IGF1R by fusing the cDNA encoding the receptor ectodomain (residues 1±944) to the cDNA of the ... direct correlation between receptor binding af®nity (Kd) and ability to prevent apoptosis for IGF-I and the IGF-I analogues (Fig 5) Essentially, the ability of IGF-I or IGF-I analogues to prevent ... Tyr27 and residues 1±6 or Glu6) have similar importance in the interaction between IGF-II and IGF1R When comparing the receptor's binding af®nities for the IGF analogues with its af®nity for IGF-I...
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T-Shirts and Suits A Guide to the Business of Creativity pptx
Ngày tải lên :
15/03/2014, 21:20
... time, fashions and changing beliefs The factors above are not in order of importance, the checklist merely provides an easy to remember acronym 28 The best way to use the checklist is to produce ... fit between selected customers and the products they want, at the right price, then advertising and promotion becomes more a matter of informing them rather than coercing them There’s no need for ... outlines the benefits of using a business ‘radar’ to monitor the changing world for opportunities and threats which could affect your enterprise for better or worse 26 ‘ Watch out! There’s stuff...
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Báo cáo Y học: The unorthodox histidine kinases BvgS and EvgS are responsive to the oxidation status of a quinone electron carrier ppt
Ngày tải lên :
17/03/2014, 23:20
... bottom panel autoradiograms of representative SDS/PAGE are shown In the top panel, the increase with time of BvgS-P and EvgS-P in the presence or absence of Q-0 and/ or dithionite is shown For ... obtained from Sigma For the determination of the effect of Q-0 on the autophosphorylation kinetics of BvgS and EvgS the kinases were incubated for 15 s, 30 s, min, or before the addition of sample ... indicators for sensor proteins such as ArcB, BvgS and EvgS As the quinones are the only components of the respiratory chain which apparently are free in their movement within the membrane, they...
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Testing Costs and Testing Capacity According to the REACH Requirements – Results of a Survey of Independent and Corporate GLP Laboratories in the EU and Switzerland potx
Ngày tải lên :
23/03/2014, 05:22
... prices for the same test This can happen when one laboratory is trying to win customers from its competitors, or because customers have loyalties to laboratories, in which case these laboratories ... laboratories for the year 2003 mention that Germany has 159 laboratories, the UK 128, France and Switzerland 44 each, the Netherlands 36, and Italy 29 These lists include independent labs and corporate ... laboratory personnel and equipment), quality of input factors, size of the testing lots, laboratory technology, and the organization of the laboratory One determinant on which we have information...
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Boom and Bust in Australian Screen Policy: 10BA, the Film Finance Corporation and Hollywood‘s ‗Race to the Bottom‘ ppt
Ngày tải lên :
23/03/2014, 12:20
... Consequently, ―nobody knows‖ beforehand whether a film will succeed or not, due to the ―random walk‖ of combinatorial uncertainties from script and production to marketing, distribution and exhibition, although ... Australia data-sets, and the FFC‘s investment in 1,165 projects, is beyond this article‘s scope Rather, the causal and explanatory factors we discuss may inform more rigorous research [FIGURE ... ―many of the failures of the local industry have been the result of commercial misjudgments — not only by the federal and state funding agencies, but also by private investors, distributors and filmmakers.‖...
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Báo cáo hóa học: " Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032" potx
Ngày tải lên :
18/06/2014, 16:20
... burden and pain from the lesions Figure shows the cutaneous lesions before and after treatment with PLX4032 A portion of the tumor was also collected for laboratory research studies according to ... tested and shown to be positive for the BRAF V600E mutation The patient was treated and achieved an excellent clinical response to PLX4032, associated with substantial reduction in the tumor burden ... consent is available for review by the Editorin-Chief of this journal Upon retesting for BRAF Figure Chest wall lesions before treatment with PLX4032 (A) and on the first day of the fifth treatment...
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– ANSWERS – Set 7 (Page 13) 102. c. A leopard, cougar, and lion all belong to the cat family; doc
Ngày tải lên :
18/06/2014, 17:20
... makes paintings; a senator makes laws The answer is not choice a because an attorney does not make laws and a senator is not an attorney Choice c is incorrect because a senator is a politician Constituents ... cannot be yellow 382 a The market is one block west of the hotel The drugstore is two blocks west of the hotel, so the drugstore is west of the market 383 c There is not enough information to ... comparison between the train and the car 381 a We know that there are Signots with buttons, or Lamels, and that there are yellow Signots, which have no buttons Therefore, Lamels not have buttons and...
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Báo cáo toán học: " An introduction to 2-fuzzy n-normed linear spaces and a new perspective to the Mazur-Ulam problem" docx
Ngày tải lên :
20/06/2014, 21:20
... satisfactory theory of 2-norms and n-norms on a linear space has been introduced and developed by G¨hler [1, 2] Following Misiak [3], a Kim and Cho [4], and Malˇeski [5] developed the theory of n-normed ... dimensional vector space into itself and V¨is¨l¨ a aa [15] gave a short and simple proof of the Mazur–Ulam theorem Chu [16] proved that the Mazur–Ulam theorem holds when X is a linear 2-normed space ... Rassias and Semrl’s theorem [18] Moslehian and Sadeghi [19] investigated the Mazur–Ulam theorem in non-archimedean spaces Choy et al [20] proved the Mazur–Ulam theorem for the interior preserving...
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Báo cáo khoa học " The nutrients of exotic mushrooms (Lentinula edodes and Pleurotus species) and an estimated approach to the volatile compounds " potx
Ngày tải lên :
28/06/2014, 11:20
... tough, rubbery and fibrous; and three flavor descriptors such as fresh fish, meat and buttery Mushroom texture can be affected by various factors like heat treatment and storage in pH ranges In their ... 1) The protein content was calculated by using the protein conversion factor 4.38% total N This estimation of protein was more accurate than the conversion factor 6.25 because of chitin or other ... factor and RDI of this vitamin is 6.6 mg for each 1000 calorie intake daily or 15–20 mg (Sencer, 1983; Demirci, 2006) In the study there was a negative correlation for the niacin level among the...
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Báo cáo y học: "Intraoperative PaO2 is not related to the development of surgical site infections after major cardiac surgery" ppt
Ngày tải lên :
10/08/2014, 09:23
... Spain Authors’ contributions JB and ET had full access to all of the study data and takes responsibility for the integrity of the data and the accuracy of the data analysis Both authors contributed ... superficial or deep incision SSIs and 26 (2.5%) organ/space SSIs The intraoperative and postoperative PaO values were not associated with an increased risk of SSI either by univariate or multivariate ... surgery patients is not related to SSI rate The strategy of administering supplemental inspired oxygen to reduce the incidence of SSIs does not appear to be clinically useful Author details Departament...
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