dots insights from user studies on dynamic network visualizations

... Rational and usable wave equation soil model based on field test correlations Proceedings, FHWA International Conference on Design and Construction of Deep Foundations, Orlando, Florida, USA Simons ... foundation solution to the construction site in which soil conditions are varied from distance to distance, compared to the case with only a few static load tests Additionally, the accurate prediction ... International Seminar on the Application of Stress-Wave Theory on Piles, Stockholm; 3-22 Holeyman A.E (1985) Dynamic non-linear skin friction of piles Proceeding of the International Symposium on Penetrability...

Ngày tải lên: 21/05/2016, 22:14

... BS-RNase as a positive control For a negative control, the proteins were also assayed on nontumor 3T3 cell cultures at a final concentration of 100 lgÆmL)1, and found to be nontoxic (Fig S2) The ... function of urea concentration (insets in Fig 5), whereas the curves of NCDs displayed two transitions (Fig 5) The values of urea concentration at half-completion of transition, C½, are shown ... concentrations, but focusing on the parent BS-RNase and on the single-point R80S variant The results are reported in Fig 7, where the folded fraction is reported as a function of the urea concentration...

Ngày tải lên: 22/03/2014, 17:20

... scavenging and remobilization when the cells are under stress and consequently mononucleotide phosphate concentrations are high 5862 Materials and methods Cloning and purification of St SurE The SurE ... from one subunit coordinates with the metal ion bound to the other subunit In St SurE, this loop is in a closed conformation As Iwasaki and Miki [10] report, only if the loop is in an open conformation ... by residues 34–50 undergoes conformational change from a ‘closed’ to an ‘open’ form The shift in the position of the loop away from the metal ion leads to the formation of two interprotomer active...

Ngày tải lên: 18/02/2014, 14:20

... conformations in E53QbsSHMT-Gly In one conformation, the carboxylate group forms hydrogen bonds with R357, as in bsSHMT-Gly [12] In the second conformation, the carboxylate forms hydrogen bonds ... present close to the position corresponding to the second conformation of the carboxylate group (Fig 2A,B) The hydrogen bonding between Q53 and the second conformation of carboxylate of Gly found ... first conformation are similar to those described for the bsSHMT-Gly-FTHF [12] The second conformation is stabilized mainly by hydrogen bonding to atoms from the symmetry related subunit One of...

Ngày tải lên: 18/02/2014, 16:20

... functioning, total cognition, and somatization; (d) social ties, depression, mastery, and self-efficacy Nine regression analyses were conducted (corresponding to the three types of support from ... sampled on the basis of age and both physical and cognitive functioning from three community-based cohorts of the National Institute on Aging’s Established Populations for Epidemiologic Studies ... transaction between two or more people, the information provided might be biased by individual characteristics that filter perceptions A second limitation is that the study focused only on individuals...

Ngày tải lên: 06/03/2014, 15:20

... application of this assay Under all conditions used, the reaction rate is directly proportional to the EcIPDC concentration and independent of the concentration of the auxiliary enzyme, confirming ... pseudo first-order rate constants of reconstitution calculated from these time courses show a hyperbolic dependence on the ThDP concentration (at saturating Mg2+ concentration), pointing to a two-step ... reaction was started with EcIPDC (10.7 lgÆmL)1) at ThDP concentrations of 250, 120, 20, 12, 6, 3, 1.5, and 0.5 lM (from left to right) Inset, dependence of the rate constant of reconstitution on...

Ngày tải lên: 08/03/2014, 02:20

... titration experiments From the theoretical calculations of Kd for the ratios of sugar-free to sugarbound peak intensities as a function of sugar concentration, the protein concentration was lowered ... exchange regime Thus, the configuration at the hemiacetal carbon of galactose may affect the dissociation constants By contrast, because chemical-shift changes upon the addition of sugars at subdomain ... transition under conditions of slow exchange on the chemical-shift timescale, the dissociation constant, Kd, is given by K d ¼ ½PŠ½LŠ=½PLŠ Here, [P], [L] and [PL] are the respective concentrations...

Ngày tải lên: 23/03/2014, 04:21

... spectra of the corresponding nonsubstituted monosaccharides [26] These displacements were caused by the glycosylation effects on the linkage carbons and confirmed the sugar-substitution pattern determined ... (Table 2) Having the D configuration, ara4dHex, FucI and FucII occur in the 4C1 conformation and L-Rha in the 1C4 conformation In the 1H NMR spectrum, all four anomeric protons gave poorly resolved ... h), and monosaccharides were converted conventionally into alditol acetates [15] and analysed by GLC-MS The content of ara4dHex was estimated by using the Cynkin–Ashwell method [16], the content...

Ngày tải lên: 23/03/2014, 17:22

... Distributions of Semantic Networks Connectedness For every network, we computed the strongly connected component (SCC) such that for all nodes (semantic terms) in the SCC, there is a path from any ... Joint Degree Distribution of the Semantic Networks from a highly-connected seed page should prefer a breadth-first strategy Conclusion Outdegree Outdegree Discussion The above studies show that many ... as Madonna and Michael Jackson”, two nodes Madonna and Michael Jackson with an edge e=(Madonna, Michael Jackson) would be created in the graph G Figure shows a small example of the singer network...

Ngày tải lên: 30/03/2014, 21:20

... and the Bronze Age and Iron Age of the MDS region With one exception, the argumentation tries to stay clear of a reliance on ethnographic examples.The exception concerns the assumption of a mutual ... generation to generation But throughout the centuries building traditions did change considerably A Middle Bronze Age house differs in construction from a Late Iron Age example, even though both belong ... analytical concepts If one looks beyond the culturally-specific perception of the landscape, their patterns of behaviour represent two different adaptations to the same physical conditions, one successful,...

Ngày tải lên: 11/06/2014, 13:59

... were not present among the strains isolated from Central Java, Indonesia and rare among strains isolated from Hesse, Germany Jonsson et al [17] described that the two S aureus fibronectin-binding ... cultures from Hesse, Germany revealed an amplicon size of 780 bp Amplification of the X-region of spa gene of the S aureus isolated from Central Java, Indonesia showed two different sized amplicons ... cultures from Central Java and cultures from Hesse were non-hemolytic Cultivation of the bacteria on nitrocellulose membranes revealed that cultures from Central Java and 11 cultures from Hesse...

Ngày tải lên: 07/08/2014, 17:22

... )%0.04( )%3.72( sisolucrebuT )%6.82( )%6.36( htnimleH )%6.82( )%8.4( )%0.04( gnihguoC on deknaR on deknaR on deknaR on deknaR motpmys/esaesiD oremovM amodoD noitpmusnoc klim hguorht dettimsnart eb ... retrauq a ,stluser TMC roF selbairav yrotanalpxe tsniaga stluser esylana ot desu erew level mraf ta CCT dna CVT yb denifed ytilauq klim dna sititsam lacinilc ,slevel retrauq ro woc ta stluser erutluc ... detroper sa retaw dna erutsap hguone teg swoc nehw )yaM ot hcraM( sniar gnol eht gnirud rucco ot ylekil si noitcudorp klim devorpmi taht elbissop si tI erutsap hguone evah ton od saera eht fo tsom nehw...

Ngày tải lên: 07/08/2014, 18:21

... pyrazinamide results from enhanced urate reabsorption [19,20] Recent genome-wide association studies for serum urate concentrations Candidate-gene association studies depend on current knowledge ... association studies showed a region containing the genes leucine-rich repeatcontaining protein 16A (LRRC16A) and SCGN, chromo­ somal locus 6p22.2, as a region associated with serum urate concentrations ... genome-wide association studies showed a relationship between SLC16A9 and serum urate concentrations, but the function of MCT9 remains unknown http://genomemedicine.com/content/1/12/118 LRRC16A...

Ngày tải lên: 11/08/2014, 12:20

... the conditions for illness actions in particular Furthermore, we argue that the diminished capacity due to hardship and deaths within the networks made the dynamics of illness action discontinuous ... their decisions was uncertain Fatima's situation was one of the most vulnerable among the informants and her story sums up the unpredictability and discontinuity of the life condition of the people ... available from: http://www.globalizationandhealth.com/content/6/1/8Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in...

Ngày tải lên: 11/08/2014, 14:21

Ngày tải lên: 20/10/2014, 21:48

... purification 46 2.7.1 Plasmid construction and transformation 46 2.7.2 Induction of protein expression 47 2.7.3 Protein purification 47 2.7.4 Protein concentration measurement ... nutrient uptake, reduction in carbon fixation or alterations in biosynthesis or activity of hormones Hormones can be very important for the virus infection CaMV infection in the etr1-1 and ein2-1 ... appear to be derived from the interaction of virus and host 11 components and not from general metabolic perturbations caused by the overproduction of viral components and competition for host resources...

Ngày tải lên: 11/09/2015, 10:17

... Gopalakrishnakone, P., Cloning and molecular characterization of BmHYA1, a novel hyaluronidase from the venom of Chinese red scorpion Buthus martensi Karsch Toxicon (In press) doi: 10.1016/j.toxicon.2010.04.009 ... hyaluronan from the cell surfaces The further study about its effect on CD44 molecules showed that the environmental hyaluronidase (BmHYA1) can modulate the expression of CD44 variant IX Publications ... targeting on ion channels 10 1.4 Low molecular weight toxins from the venom of BmK scorpion 11 1.5 High molecular weight proteins from animal venoms 13 1.6 Hyaluronidase and its substrate hyaluronan...

Ngày tải lên: 14/09/2015, 08:48

... after incubation with conditioned media from CHO media Fig 4.6B: Hoechst 33342 staining of PC12 cells after incubation with conditioned media from CHO media Fig 4.7A: Determination of cell death ... exposed to OGD conditions 6.4.2 Effect of PLA2 on glutamate- 233 mediated insult 6.5 Conclusion 236 6.6 Future studies 238 References 240 Appendices Publications 271 Publications Koh, DC-I, Armugam, ... extraction from agarose gels 64 2.2.1.2 RNA gel electrophoresis 65 2.2.2 Enzymatic reactions 66 2.2.2.1 Restriction endonuclease digestion 66 of DNA 2.2.2.2 Ligation 66 2.2.3 Purification of nerve...

Ngày tải lên: 14/09/2015, 11:25

... Transformations of Gene Expression Information 25 iv 2.3.2 Targeted Analysis of Regions Exhibiting Coordinated Gene Expression Suggests a Correlation with DNA Amplifications and Deletions ... of the network and the constituent modules were assessed to gain insight into the organization of information in gene coexpression networks Four datasets comprising >300 tissue samples from four ... expression level (48), others have reported that genes on regions of chromosomal amplification are rarely associated with increased expression (9) In addition, most of these reports have focused on...

Ngày tải lên: 15/09/2015, 17:09

... O2; iron as a catalyst) Conversely, superoxide favours the Fenton reaction by releasing iron from ironcontaining molecules It is widely accepted that tight regulation of iron assimilation prevents ... invasion The suppression of iron efflux from macrophages hence, reduction in plasma iron and increased synthesis of ferritin by macrophages to accommodate iron from phagocytosed lactoferrin iron ... respectively, we confirmed that iron is one of the major metal ions responsible for the generation of free radical (Fig 3.1D) Surprisingly, DNA nicking was inhibited only at high concentrations of potassium...

Ngày tải lên: 04/10/2015, 17:06