dose response relationships and foodborne disease

... (risk equivalent dose) is the dose- response relationship for radiation induced cancer in units of dose and b is the initial slope, which is the slope of the dose- response curve at low dose The modifying ... average organ dose as long as the dose- response curve is linear At high dose it could be that the dose- response relationship is non-linear and as a consequence, OED replaces average dose to quantify ... inhomogeneous dose distributions, cancer risk is proportional to average dose only for a linear dose- response relationship For any other dose- response relationship, cancer risk is proportional to OED Dose- response...

Ngày tải lên: 13/08/2014, 16:20

... enterovirus-71-related hand, foot, and mouth disease Lancet 1999;354:1682–86 Alexander Jp Jr, Baden L, Pallansch MA, Anderson LJ, Enterovirus 71 infection and neurologic disease United States, ... Enterovirus is resistant to alcohol and phenolic disinfectants; Linen and Waste from patients suffering from HFMD should be handled with care, and wash hands after handling 7.5 Advice given to the ... B2, B5 and EV71 HFMD is sometimes confused with foot -and- mouth disease of cattle, sheep, and swine The latter is caused by a virus Aphthovirus which belong to the family of Picornaviridae .and will...

Ngày tải lên: 05/03/2014, 12:20

... summarized in the Foot-andMouth Disease (FMD) Response: Ready Reference Guide—Understanding Response Strategies 4.1 RESPONSE GOALS The goals of an FMD response are to (1) detect, control, and contain FMD ... NIMS, and other Foreign Animal Disease Preparedness and Response Plan (FAD PReP) documents  Describes U.S Department of Agriculture preparedness and response activities, both domestic and international, ... (voice and TDD) USDA is an equal opportunity provider and employer DRAFT—June 2012 xiv Chapter Introduction and FMD Information 1.1 INTRODUCTION TO RESPONSE PLAN This Foot -and- Mouth Disease (FMD) Response...

Ngày tải lên: 08/03/2014, 23:20

... cases and deaths, respectively, were: 11 and in 2006; 12 and in 2007; 373 and 14 in 2008; and 29 and in 2009 A Guide to Clinical Management and Public Health Response for Hand, Foot and Mouth Disease ... mouth disease (HFMD) [ ii ] Hand, foot and mouth disease – epidemiology Hand, foot and mouth disease – prevention and control Disease outbreaks Enterovirus A, Human I Regional Emerging Disease ... Management and Public Health Response for Hand, Foot and Mouth Disease (HFMD) WHO Library Cataloguing in Publication Data A Guide to clinical management and public health response for hand, foot and...

Ngày tải lên: 28/03/2014, 09:20

... suriv esaesid htuom dna toof eht gnidocne seniccav AND dimsalp ehT noitaniccav lanoitnevnoc ot evitanretla tneiciffe dna efas a sedivorp noitazinummi AND erutcurts citnehtua eht ni sepotipe lanoitamrofnoc ... esaesid htuom-dna-toof tsniaga eniccav AND A Y eiX ,TZ gnehS ,WE nahC ,WF niS ,CS gnehC ,TH gnoW 31 9471-5471 ,952 ,3991 ecneicS nietorp lariv a gnidocne AND fo noitcejni yb azneulfni tsniaga ... secnahne eniccav AND VDVB fo ycnavujda enikotyC EM snilloC ,J eilnworB ,I nospmohT ,I noriboN 777-567 ,81 ,9991 eniccaV stcepsorp dna ssergorp ,selpicnirp :seniccav desab-ANR dna AND PN ofitseR...

Ngày tải lên: 07/08/2014, 18:21

... were 92.2 Gy and 1.52, 101.2 Gy and 0.98, 100.0 Gy and 1.05, and 94.6 Gy and 1.34 For RION in patients treated twice daily and a/b = Gy, parameter values were 91.0 Gy and 1.52, 120.9 Gy and 0.76, ... parameters, D50 and g for RION in patients treated once daily were 96.0 Gy and 1.34, 107.6 Gy and 0.82, 103.9 and 0.95, and 98.1 Gy and 1.20 for the logistic, log-logistic, Poissonbased and probit ... D50 = 80 Gy and g = 1.5 Page of 10 Poisson-based, logistic and probit models The authors carefully considered the location of the maximum doseresponse slope and maximum normalized dose- response...

Ngày tải lên: 09/08/2014, 09:20

... Martinez-Lavin M: Biology and therapy of fibromyalgia: Stress, the stress response system, and fibromyalgia Arthritis Res Ther 2007, 9:216 Fontenele JB, Félix FHC: Fibromyalgia and related medically ... and nociception modulation? J Musculoskeletal Pain, in press Stewart J, Taneja I, Medow MS: Reduced central blood volume and cardiac output, and increased vascular resistance during static handgrip ... Arthritis Research & Therapy Vol No Félix and Fontenele Competing interests The authors cite their own work on the subject that is currently...

Ngày tải lên: 09/08/2014, 10:21

... low -dose aspirin and a diagnosis of CVD based on appropriate International Classification of Disease, Ninth Revision (ICD-9) codes (both coronary artery disease and thrombotic cerebrovascular disease) ... arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease ... presentation (http://www.dartnet.info/media/LowDoseASAandCVDpreventionSlides pdf) and one page information sheet (http://www dartnet.info/media/LowDoseASAEvidenceSummaryforClinicians.pdf) are available...

Ngày tải lên: 10/08/2014, 11:20

... an Emax doseresponse model: E0 + E0i + Emax × exp(Emi ) × doseij ED50 + doseij (2) where i is an index for patient and j for study day (14 or 15), E is the response to placebo, and E0i and E mi ... bronchodilators in COPD), a dose response is established and a target dose can be selected as the smallest dose that differs from placebo and has both a clinically relevant effect and an acceptable safety ... the original dose selection Conventional dose- ranging trials rely on hypothesis testing and use contrast statistics to compare dose levels and determine the existence of a dose response Using...

Ngày tải lên: 12/08/2014, 13:22

... in Tables and In (a) and (b) patients without plateau effect on the dose response curve are represented In (c) and (d) patients with a plateau effect on the MPAP dose response curve and showing ... in Tables and In (a) and (b) patients without plateau effect on the dose- response curve are represented In (c) and (d) patients with a plateau effect on the MPAP dose- response curve and showing ... analysis of variance (dose- response curve) Effects of septic shock on dose response curves At control, hemodynamic and respiratory parameters were the same for both groups Dose- response curves of...

Ngày tải lên: 12/08/2014, 18:20

... Study on Air Pollution and Lung Diseases in Adults (SAPALDIA) [49,50] Similar to studies from developed countries, we found a dose- response relationship between exposure to ETS and respiratory symptoms, ... questionnaire responses and measurements using a custom data entry program (Delphi programming language and SQL server DBMS) The questionnaire included main sections; socio-demographics, general health and ... (0.7–2.0) 1.0 (0.5–1.9) P Dose- response 0.6 0.3 0.3 0.4 0.7 * Odds ratio and 95% confidence interval for the relation between ETS score tertiles (lower being referent) and respiratory symptoms/diagnosis...

Ngày tải lên: 12/08/2014, 18:21

... cng cú th b mc bnh Lch s v a d bnh 1929: xy ln cui cựng U.S 1953: xy ln cui cựng Canada and Mexico 1993: Italy 1997: i loan 2001: United Kingdom Cỏc v dch khỏc xy nm 1967-68 v 1981 Lch...

Ngày tải lên: 22/08/2013, 10:54

... Portugal and Italy report overweight and obesity levels exceeding 30% among children aged 7-11 The rates of the increase in childhood overweight and obesity vary, with England and Poland showing ... a strong focus on promotion and prevention, including in the area of nutrition and physical activity, and foresees a new action strand on the prevention of specific diseases Questions on which ... Transport and urban planning policies can ensure that walking, cycling and other forms of exercise are easy and safe, and address non-motorised modes of transportation The provision of safe cycling and...

Ngày tải lên: 14/02/2014, 13:20

... PVCs and arrhythmias On the other hand, blocking miR-1 function with antisense oligoribonucleotides was found to normalize the expression of Cx43 and Kir2.1, prevent QRS and QT prolongation, and ... miR126, miR-221 and miR-222 might be important modulators of vascular disease and vessel remodeling Heart failure Because cardiac hypertrophy, fibrosis, arrhythmia, and coronary artery disease can ... miR-21 limits PTEN function and causes activation of the Akt pathway and increased matrix metalloprotease-2 expression in cardiac fibroblasts MicroRNAs and cardiovascular diseases Connective tissue...

Ngày tải lên: 14/02/2014, 19:20

... in caries, and obstinate sore legs DYSPNOEA Pituitosa Sauvages i 657. "Boiled in water, or wine, and drunken doth cut and consume the thicke toughnesse of grosse, and slimie flegme, and naughtie ... water or sugar, doth scoure and clense the brest, ripeneth and bringeth foorth tough and clammie flegme It openeth also the stoppage of the liver spleene and milt, and of the inwarde parts." GERARDE ... between two and three thousand annually I soon found the Foxglove to be a very powerful diuretic; but then, and for a considerable time afterwards, I gave it in doses very much too large, and urged...

Ngày tải lên: 19/02/2014, 11:20

... PrP1 and human PrPC, 62% between zebrafish PrP1 and PrP2, 66% between zebrafish PrP1 and Fugu PrP1, and 57% between zebrafish PrP1 and Fugu PrP2 sequences (Fig 2) Conserved sequence motifs and amino ... stPrP-1 and stPrP-2 [10,11] and renamed in this study PrP1 and PrP2, respectively Given that the zebrafish PrP1 sequence could be aligned in its entirety with zebrafish PrP2, Fugu PrP1 and PrP2, and ... Ala) and is included in a region with similarities to viral fusion peptides and reactive loops of serpins [28] Additional conserved sequence motifs and amino acid positions in zebrafish PrP2 and...

Ngày tải lên: 19/02/2014, 16:20

... A549, BHK, TC7, SW2, HL60 and HUVEC with respect to their response to hypoxia and reoxygenation The alkaline sedimentation profiles of HeLa and CCRF cells after hypoxia and reoxygenation already ... combined and yielded nucleosolic proteins The remaining pellet contains all DNA and structure bound proteins and is further referred to as chromatin-fraction Electrophoresis of proteins and Western ... Immunofluorescence staining of total cellular and chromatin-bound PCNA T24 were grown and incubated on coverslips Two sets of hypoxic cells and of cells reoxygenated for 10 and 30 were prepared One set of...

Ngày tải lên: 21/02/2014, 00:20

... immunity, dose response relationships, and the dynamic nature of acute immune responses need to be considered Physicians certainly recognize neonates and infants as being immunologically immature and ... receptors on T- and B-cells The capability of the adaptive immune response to recognize and react against thousands of specific antigens is dependent on T- and B-cell receptor expression and binding ... and secreted proteins that stimulate, inhibit, and regulate the immune response such as cytokines and interferons; (3) humoral immunity including B-cells, plasma cells, and immunoglobulins; and...

Ngày tải lên: 22/02/2014, 05:20

... Command, Finance, Logistics, Operations, and Planning (Fig 1) Duties and responsibilities of the sections are outlined below and also in Fig The Command Section is led by one Incident Commander and ... federal and state agencies, and a number of foreign countries have shared their expertise and their time to create this seventh edition The Chair and Co-Chair of the USAHA Committee on Foreign and ... meaningful and less meaningful Less meaningful because of the rapid movement of diseases around the world and the increasing likelihood that one of these will be found here (Exotic Newcastle disease and...

Ngày tải lên: 22/02/2014, 05:20

... Indonesia in 2003 were 70% for OPV and DPT and 72% for measles (WHO, 2004), and these rates of immunization coverage are consistent with overall rates of coverage for three doses of DTP of 69% reported ... to explain the purpose of the NSS and data collection to each child’s mother or caretaker, and, if present, the father and/ or household head; data collection and phlebotomy proceeded only after ... OPV-3, DPT-1, DPT-2, DPT-3, and measles vaccines; partial defined as receiving at least one of the seven vaccine doses, and no receipt as receiving none of the seven vaccine doses 2Geometric mean (95%...

Ngày tải lên: 05/03/2014, 12:20