does patient agree to the referral or is the referral mandated
Báo cáo khoa hoc:" Human MMP28 expression is unresponsive to inflammatory stimuli and does not correlate to the grade of intervertebral disc degeneration" doc
Ngày tải lên :
11/08/2014, 07:21
... proinflammatory mediators [10,25-27], which are know to regulate several MMPs [1], we hypothesized that MMP28 expression could be increased in an inflammatory context Therefore, the aim of this study ... the responsiveness of MMP28 to HDAC inhibitors Therefore, it is unknown whether most other cell types would show a behavior similar to HeLa cells (regulation) or to IVD cells (no regulation) ... to date In contrast to many other MMPs, MMP28 is not regulated by various inflammatory mediators (IL-1b, TNF-a, LPS) or the HDAC inhibitor trichostatin A Future studies Authors’ contributions...
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Tài liệu Báo cáo khoa học: Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration ppt
Ngày tải lên :
18/02/2014, 12:20
... high storage concentrations to low assay concentrations of 2–3 ngÆmL)1, which is below the limit for the ATP tetramerization effect, the enzyme would be expected to dissociate to the dimer form ... Km and the tetramer has low Km, and the ratio between the two forms depends on the dThd 574 concentration [24] According to this model, the simultaneous presence in the assay of the two forms will ... values is displayed by the dimer forms These observations strengthen the previous hypothesis that the dimer ⁄ tetramer interchange of TK1 with low ⁄ high catalytic efficiency is a fine-tuning mechanism...
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tv commercials how to make them or how big is the boat
Ngày tải lên :
01/06/2014, 11:41
... Needless to say, we reedited the spots and added the disclaimer In another case, everyone, including the director, the producer, the production assistant, the art director, the editor, and even the ... on -the- spot decisions As is the case in all levels of production, the client is tempted to voice approval or disapproval or to offer advice to the director as the shoot progresses However, as is the case ... client, that is paying for the shoot And it is the agency that should be the voice that speaks for the client at the shoot The director will almost always direct his or her questions to the agency...
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Báo cáo hóa học: " Impairment of the CD8+ T cell response in lungs following infection with human respiratory syncytial virus is specific to the anatomical site rather than the virus, antigen, or route of infection" pdf
Ngày tải lên :
20/06/2014, 01:20
... non-respiratory infection, and (v) whether there is a difference in the percentage of virus-specific IFNγ + CD8+ T cells in the lungs versus the spleen after respiratory and non-respiratory infections ... mechanisms for this tissue-specific impairment could be a lack of factors necessary to maintain CTL effector functions in lung tissue [4], defective signaling [1,3], or excessive upregulation and /or ... monitored using a peptide, TYQRTRALV, from the nucleoprotein NP (amino acids 147–155) that is the immunodominant CTL epitope in the H-2Kd background [13] CD8+ CTL specific to the RSV M2-1 or influenza...
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Báo cáo y học: "Background: Percutaneous tracheostomy (PT) has gained an increasing acceptance as an alternative to the conventional surgical tracheostomy (ST). In experienced hands, and with proper patient selection, it is safe, easy and quick." docx
Ngày tải lên :
12/08/2014, 18:20
... tracheostomy is superior to the ‘blind’ one Furthermore, the significance of operator experience, anatomical consideration and individualization in decision making is not discussed in these studies ... [10,41] This may occur with a tracheostomy below the third or fourth tracheal ring Another important complication is damage to the posterior tracheal wall due to the puncture needle or dilators, which ... useful to reduce the risk of bleeding Hyperextension of the neck for anterior displacement of the trachea is crucial Therefore, PT is not recommended when manipulation of the cervical spine is contraindicated...
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Báo cáo y học: "Bench-to-bedside review: The initial hemodynamic resuscitation of the septic patient according to Surviving Sepsis Campaign guidelines – does one size fit all" ppt
Ngày tải lên :
13/08/2014, 11:22
... about the reason for this inadequacy, nor does it provide guidance as to the optimal therapeutic approach On the other hand, a normal or high ScvO2 value does not rule out persistent tissue hypoxia, ... turn, to the observed very low ScvO2 values One has to note that the use of the word ‘early’ in EGDT refers to the time from the patient s admission to the institution of goal-directed therapy ... admitted to the hospital through the ED and the ICU, and had higher mortality for sepsis, most probably due to disparities in disease prevention and care of pre-existing conditions before sepsis onset...
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Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&
Ngày tải lên :
25/10/2012, 10:06
... disagree", "disagree", and "somewhat disagree" For MSS data analysis, "strongly agree" , "agree" , and "somewhat agree" were combined into the category "agreed" "Strongly disagree", "disagree", and ... disagree" were combined into the category "disagreed" Tolerability measures Tolerability was based on spontaneous reports of AEs Any AEs were coded using the Medicinal Dictionary for Regulatory ... with the following responses to each of the survey questions using descriptive statistics: "strongly agree" , "agree" , "somewhat agree" , "strongly disagree", "disagree", and "somewhat disagree" The...
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Tài liệu Which Bank Is the “Central” Bank? An Application of Markov Theory to the Canadian Large Value Transfer System doc
Ngày tải lên :
16/02/2014, 12:20
... normalized BCL vectors for each bank This approach is based on the premise that money flows out of a bank in the proportions given by the BCLs the bank has with the other banks We also allow the possibility ... stationary vector represent the fraction of time a dollar spends at each location in the network This stationary vector is our prediction for the distribution of daily liquidity The bank with the highest ... value (the former is measured on the horizontal axis and the latter is measured on the vertical axis) for a given bank on a given day Hence, there are 272 × 14 = 3808 points on the graph If the...
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Tài liệu Báo cáo khoa học: The PA-TM-RING protein RING finger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING finger domain is released to the cytoplasm by proteolysis ppt
Ngày tải lên :
18/02/2014, 08:20
... signal to move into the nucleus either on its own or with the help of an adaptor protein that facilitates entry into or retention in the nucleus – it is possible that the adaptor protein is more ... and storage activity [11,12] AtRMR1 was subsequently determined to be responsible for sorting the bean storage protein phaseolin to the protein storage vacuole [13] and was shown to bind to C-terminal ... form a complex with the nuclear adaptor Fe65 and the histone acetyltransferase Tip60 in order to target to the nucleus [61,62] Other ICDs function exclusively in the cytoplasm The adhesion protein...
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Tài liệu Báo cáo khoa học: What MAN1 does to the Smads TGFb/BMP signaling and the nuclear envelope Luiza Bengtsson pdf
Ngày tải lên :
19/02/2014, 02:20
... was first discovered as one of the autoantigens for the autoantibodies from a patient with collagen vascular disease [18] MAN1 is an integral membrane protein of the INM and belongs to the LEM (Lap2emerin-MAN1)-domain ... Signaling is initiated by binding of the cytokine to a homodimeric complex of cytokine receptor type II, which recruits type I receptor and activates it by phosphorylation Phosphorylated and thereby ... ª 2007 The Author Journal compilation ª 2007 FEBS 1377 What MAN1 does to the Smads L Bengtsson of the nuclear pore complexes, MAN1 is unlikely to block Smad entry into the nucleus It is also...
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WHY IT IS SO HARD TO GET SAFE WATER TO THE POOR – AND SO PROFITABLE TO SELL IT TO THE RICH pdf
Ngày tải lên :
07/03/2014, 00:20
... Berne, to focus further on the market creation approach to development Foreword : François Muenger, Senior Water Advisor, SDC Peer review: Armon Hartmann, former Senior Water Advisor, SDC Editor ... factory adds plastic parts worth more than three times the ceramic cost It is somehow the same as if a tyre or motor factory tries to sell cars.This question will return later in this book 41 Disseminating ... rich 7, they pay an excessive proportion of their income for water.8 To make matters even worse, the water they get is often contaminated or is being contaminated during transport, storage or consumption...
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Báo cáo khoa học: Structure of Streptococcus agalactiae serine⁄threonine phosphatase The subdomain conformation is coupled to the binding of a third metal ion pptx
Ngày tải lên :
07/03/2014, 09:20
... stalled at R-factors of 26 and 30% This may be due to real disorder in the crystal as the mean B-factor from the refinement was rather high ˚ ˚ (78.5 A2) – as was the Wilson B-factor (77 A2) It ... map The model was, however, rather incomplete; 20% of the residues were either missing or modeled in a wrong conformation (checked against the final coordinates) due to the poor quality of the ... conformation of the flap domain is related to binding of the third metal ion or the substrate The ligands for Mn3 in MtSTP were Asp118, Asp191 and Ser160, the last coming from the flap domain [9] There...
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Báo cáo khoa học: Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C pdf
Ngày tải lên :
08/03/2014, 08:20
... which is a G-protein-coupled receptor, is essential for targeting the receptor to caveolin-rich domains in the plasma membrane [45] Glycosylation of the b-adrenergic receptor is also important for ... indicating that only the ligandresponsive form of the receptor is perhaps routed to the lysosomal compartment for degradation The continued presence on the surface of cells of the 130 kDa form, even on ... that distinct regulatory mechanisms are operative in the two receptors, as indeed is the case, and shown in the studies described here Until date, the role of glycosylation in either GC-A or GC-B...
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Báo cáo khoa học: "Analysts Grammar or Japanese to the Nu-ProJect" pdf
Ngày tải lên :
08/03/2014, 18:20
... o n to determine the scopes Noun-1 If 'TO' two "TO* particles Noun-2 appear 'TO' tn the 'NO" NOUN-3 the r i g h t boundary of the scope of the ... l a t i o n s h i p s by themselves, and when these nouns appear as antecedents | t is o f t e n the case t h a t they ft11 the gaps of the corresponding deep cases tn the r e l a t t v e clauses ... l e or a 11mtted number of words such as r u l e s concerned wtth c o l l o c a t i o n s among words These r u l e s are strong tn the sense t h a t they almost always succeed They are stored...
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From Patient Data to Medical Knowledge The Principles and Practice of Health Informatics ppt
Ngày tải lên :
15/03/2014, 12:20
... able to listen more constructively to their patients’ stories if they tried to understand them as stories, rather than attempting to express them in the structured and standardised format of the ... examinations, what the patient s symptoms are The trick in diagnosis is to work out, given the symptoms, what the disease is Or at least what the disease probably is Or, maybe, what the management ... of the information gathering recorded in patient histories is not definitively to establish the truth but to provide an adequate basis for action For a doctor actively involved in treating a patient...
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Báo cáo khoa học: MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane ppt
Ngày tải lên :
16/03/2014, 13:20
... both localize at the OLM, suggesting a role for these proteins in photoreceptor polarity [22,24] Mpp4 is also present at the presynaptic photoreceptor membrane in the outer plexiform layer (OPL) ... adjacent to the adherens junctions (AJs) between photoreceptors and Muller glia cells At the ¨ outer plexiform layer, the most basal side of photoreceptors form synapses with bipolar and horizontal ... (Leiden, the Netherlands) and Jackson ImmunoResearch Laboratories (Amsterdam, the Netherlands) Secondary antibodies conjugated to horseradish peroxidase were purchased from Sigma Immunohistochemistry...
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Báo cáo khoa học: The antibody to GD3 ganglioside, R24, is rapidly endocytosed and recycled to the plasma membrane via the endocytic recycling compartment ppt
Ngày tải lên :
16/03/2014, 13:20
... protein may cause the lipid to be sorted on the basis of the characteristics of the protein, and such a mechanism is important for the trafficking of glycosylphosphatidylinositol-anchored proteins ... S3) Further work is required to define the precise mechanism involved in the release of R24 antibody into the extracellular medium The recycle pathway described in this work is likely to be of ... rapid internalization of the antibodies to intracellular compartments is desired for cytotoxic effects of toxins or cytotoxic drugs conjugated with the antibody [14] Neither the binding and release...
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how the use of the diary form narrative is beneficial to the
Ngày tải lên :
21/03/2014, 22:04
... when the diary form of narrative is used For instance, after Lucy had written what was happening to her when her mother passed away, the story went back in time for another important matter to ... one person was telling the whole story, the reader would see and hear what the person telling the story heard and wrote down So using, the diary, Bram Stoker could make the reader "see" exactly ... flip back through the book to look for something that he needs or wants The diary form is great! It lets a reader feel, and see how characters interpret things themselves The form lets dialogues...
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Authoring and Generating Health-Education Documents That Are Tailored to the Needs of the Individual Patient doc
Ngày tải lên :
22/03/2014, 15:21
... or the innards of HealthDoc The authoring tool, therefore, should be no more difficult for the writer to use than, say, the moresophisticated features of a typical word processor The text is therefore ... of information are persuasive to the patient For more discussion, see DiMarco, et al (1995) other parts of the system—i.e., the user interface for the clinician, the software interface to the online ... important issues for research in tailorable healthcommunication documents and their authoring have been raised during the first phase of the project The basis for tailoring health information to...
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