distribution in the body of fibrocartilage

... from binding sites on plasma proteins. Binding to plasma pro- tein is equivalent to a depot in prolong- ing the duration of the effect by retard- ing elimination, whereas the intensity of the effect ... conditions of license. Binding to Plasma Proteins Having entered the blood, drugs may bind to the protein molecules that are present in abundance, resulting in the formation of drug-protein complexes. Protein ... complexes. Protein binding involves primarily al- bumin and, to a lesser extent, !-globu- lins and acidic glycoproteins. Other plasma proteins (e.g., transcortin, trans- ferrin, thyroxin-binding globulin)...

Ngày tải lên: 22/01/2014, 00:20

Ngày tải lên: 05/09/2013, 09:08

... consumers of the product can reduce the value of the product to the customer. 50. The “image” of a brand is therefore an integral part of the product, and determines the willingness to pay of consumers. ... response to the free riding problem in the absence of the instruments of differential pricing, RPM, or vertical integration into internet retailing. 90. The solution of restrictions on internet ... advertising (either persuasive or informative) will increase the number of buyers who purchase the product of the manufacturer. Since the margin of the retailer is smaller than that of an integrated...

Ngày tải lên: 16/03/2014, 09:20

Ngày tải lên: 20/06/2014, 22:20

Ngày tải lên: 21/06/2014, 11:20

... than in the inheritance case in that no sharing map is involved; an attempt to vm_write one mapping of the memory object would merely replace that mapping, rather than reflecting it in other ... validation - Finally, the kernel informs the hardware physical map module of the new virtual to physical mapping. With the exception of the hardware validation, all of these steps are implemented in a ... only in the organization of distributed and parallel applications, but in the implementation of the operating system kernel itself. Mach uses memory-mapping techniques to make the passing of large...

Ngày tải lên: 12/09/2012, 15:05

... purposes) of portacaval shunting, thereby decreasing first pass metabolism; decrease in quantities and affinity of plasma proteins, thereby increasing free-drug levels; increase in volume of distribution ... Carbamazepine-induced increase in total cholesterol is primarily due to an increase in HDL [34]. This occurs during the initial weeks of therapy, per- sists throughout treatment and reverses in the ... modifications should include avoidance of refined carbohydrates, including sweetened drinks, increased intake of omega-3 fatty acid, and small amounts of protein with each meal [11]. Behavioral inter- ventions...

Ngày tải lên: 25/10/2012, 10:51

... surrounding cytoplasmic membrane in at least 10% of invasive carcinoma cells or presence of mem- branous staining in less than 30% provided that the staining is intense (++) Score 3: Presence of intense ... CHAPS) at the ratio of 5:1. Sera were then diluted again with binding solution at the ratio of 10:1 and were applied in 100 µL amounts in the wells on the chip. Protein chips on which the samples ... 0.70 for Bc1 in all groups. The relevance of this finding is that it was the result of the first sub- group analysis for these biomarkers. Bc1 should therefore be studied in terms of tumoral...

Ngày tải lên: 25/10/2012, 11:15

... between the angles of the dural opening. Th e most significant step involves con - structing small supporting pillars on the bilateral sides of the vessels as they pass the edge of the dural window ... Fol- lowing removal of part of the skull, they performed dural incisions in a stellate fashion. In this step, it is important that entrance points of major vessels are close to the midpoint between ... l s. The process was repeated in parallel rows of incisions so that each incision in one row wa s adjacent to an intact dural bridge in the rows on either side. The same course was then performed,...

Ngày tải lên: 25/10/2012, 11:40

... transport chain would nor- malize the pathways involved in the development of the oxidative stress (68). If our findings are proven by further studies in- volving a larger number of patients, ... minutes, which then switched to the opposite polarity for another 11.5 minutes. The device was designed to switch the di- rection of current flow halfway through the cycle. The resulting cycle ... role in the pathogenesis of both types of diabetes mellitus and cardiovascular diseases including hypertension. The low levels of antioxidants accompanied by raised levels of markers of free...

Ngày tải lên: 26/10/2012, 09:39

... been trained to produce their own compression stockings, sleeves or gloves. The use of these compression mechanisms gives a certain independence of patients allowing them to return to their ... still required because of the reductions in the size of the limb. Because of this need of constant adjustments, we noticed that treatment centers re- quire the services of a professional seamstress. ... depending on several factors such as, for example, the weight and the fitness of the patient and the duration of exercises. Compression mechanism One of the most important weapons in the treatment...

Ngày tải lên: 26/10/2012, 09:39

... withdrawn from the study (without penalty) if, in the opinion of the treating physician, it was not in the patient’s best interest to continue. For instance, if during the course of the study ... including glucosamine and chondroitin, one month prior to study and during the study, other than multivitamin and mineral supplements containing vitamins and minerals as the sole medicinal ingredients ... with weight bearing, including walking and standing, and improves with rest (4). Other symptoms include morning stiffness and gelling of the involved joint after periods of inactivity. Currently,...

Ngày tải lên: 26/10/2012, 09:48

... re-established. The increase of the oxygen gradient facilitates the transportation of toxins and inhibitors inducing thereby the wound healing [16]. As a result of the increased angiogenesis, the local ... not often used in orthopaedic surgery. In this study, we report our experience on the management of bacterial infections and/or draining sinus of the hip joint by means of the V.A.C. - therapy. ... seem to overstrain the clearance function of the V.A.C therapy, thus being probably the reason for the system failure in the infection treatment in case 10. One limitation of our study is...

Ngày tải lên: 26/10/2012, 09:53

... by the ratio in which the antibiotics are mixed into the cement and therefore, the total dose of antibiotics should not exceed 10% of the weight of the cement in order to avoid fracture of the ... safety. The most commonly used antibiotics in ALC include tobramycin, gentamicin and vanco- mycin [26]. The combination of vancomycin and one of the aminoglycosides provides a broad spectrum of ... available; thus, the diagnosis relies on the surgeon’s judgement of the clinical presentation, the findings on physical examination and the interpretation of relevant inves- tigations. The treatment...

Ngày tải lên: 26/10/2012, 09:53

... (drain- ing sinus, pneumonia, etc.). Despite the retrospective design of our study and the limited possibility of in- terpreting these findings and their causes, this rate indicates that these ... procedure in the treatment of hip joint infec- tions over the past two decades. Depending on the definition of infection eradication and reinfection, hip spacers have reportedly a success rate of ... between Int. J. Med. Sci. 2009, 6 http://www.medsci.org 272 sion of the haematoma is an indispensable premise in the prevention of a wound infection. Besides draining sinus, other infections...

Ngày tải lên: 26/10/2012, 09:53

Ngày tải lên: 03/11/2012, 11:01