distribution and effects of chemicals in communities and ecosystems

... of Engineering was established in 1964, under the charter of the National Academy of Sciences, as a parallel organization of outstanding engineers It is autonomous in its administration and in ... principal operating agency of both the National Academy of Sciences and the National Academy of Engineering in providing services to the government, the public, and the scientific and engineering ... weapons in fighting Iran and in attacks on the Kurdish minority in Iraq Military leaders feared that the use of such weapons in the gulf could result in the deaths of tens of thousands of Americans...

Ngày tải lên: 16/02/2014, 01:20

... Vitamins and Minerals (EVM) • The commissioning of studies from outside contractors to increase our understanding of the water contamination incident and the passage of contaminants in the water distribution ... Aluminium Introduction General information The chemistry, absorption and bioavailability of aluminium The distribution of aluminium in the body The excretion of aluminium The toxicity of aluminium ... corrosion of metallic plumbing materials Flushing of the mains distribution system to remove the contaminated water also resulted in the disturbance of old mains sediments, mainly deposits of iron and...

Ngày tải lên: 17/02/2014, 10:20

... increased on the Alpine and Apennine peaks and this also continued in the Pliocene period, resulting in the depositing at the feet of the chains of huge deposits of sand, gravel and clay There then ... plains are those of the Tavoliere in Puglia and the Piana di Sibari in Calabria On the islands there are the plain of Catania in Sicily and that of the Campidano in Sardinia The islandsBesides the ... due to the influence of both mountains and prevailing winds The highest quantities are registered in the Alpine arc (over 3,000 mm pa in the Lepontine and Julian Alps) and on the Apennines (over...

Ngày tải lên: 21/03/2014, 22:04

... lycopene and b-cryptoxanthin in plasma, with tocopherol acetate as internal standard Clin Chem 34, 377–381 Windholz, M (1976) The Merck Index An Encyclopedia of Chemicals and Drugs, edn Merck, Inc, ... interaction of quercetin and urate can be partially explained by the interception of reactive species, chelation of transition metal ions and/ or regeneration of urate from its radical form The recycling ... Effect of quercetin on the copper-induced lipid peroxidation in preoxidized LDL In order to evaluate the effect of quercetin on the Cu2+induced LPO in pre-oxidized LDL, LDL were first incubated...

Ngày tải lên: 23/03/2014, 12:20

... dismutase and ferricytochrome c inhibited the MDA formation in the presence of urate suggesting the involvement of O2 In support of the involvement of O2 , we observed the reduction of ferricytochrome ... and b-cryptoxanthin in plasma, with tocopherol acetate as internal standard Clin Chem 34, 377381 33 Windholz, M (1976) The Merck Index An Encyclopedia of Chemicals and Drugs, 9th edn Merck, Inc, ... change to the initiation of LPO in LDL are not yet clearly established [40] In the presence of pre-existing traces of hydroperoxides both Cu2+ and Cu+ may induce LPO according to the following reactions:...

Ngày tải lên: 31/03/2014, 08:20

... cytokines, including TNF-a and IL-6 by white adipose tissue (WAT), and the activation of a network of pro-inflammatory signaling pathways, including the c-Jun NH 2-terminal kinase (JNK) and inhibitor ... key feature of obesity and links obesity to insulin resistance, impaired glucose tolerance and even diabetes Features of obesity-induced inflammation include increased production of proinflammatory ... expression of TTP in macrophages and, in turn, TTP plays a key role in nicotine-induced anti-inflammatory effect through destabilization of TNF-a transcripts Since an excess of TNF-a is involved in many...

Ngày tải lên: 18/06/2014, 22:20

... cytokines, including TNF-a and IL-6 by white adipose tissue (WAT), and the activation of a network of pro-inflammatory signaling pathways, including the c-Jun NH 2-terminal kinase (JNK) and inhibitor ... key feature of obesity and links obesity to insulin resistance, impaired glucose tolerance and even diabetes Features of obesity-induced inflammation include increased production of proinflammatory ... expression of TTP in macrophages and, in turn, TTP plays a key role in nicotine-induced anti-inflammatory effect through destabilization of TNF-a transcripts Since an excess of TNF-a is involved in many...

Ngày tải lên: 20/06/2014, 04:20

... calcineurin inhibitor, hyperbilirubinemia, and hypoalbuminemia The incidence of kidney injury increased with an increase in the number of risk factors Hypoalbuminemia also was identified as an independent ... Society of Intensive Care Medicine: Prevention of acute kidney injury and protection of renal function in the intensive care unit Expert opinion of the Working Group for Nephrology, ESICM Intensive ... colistin, the use of colistimethate instead of colistin sulphate, more adequate dose adjustment according to renal function and significant improvement of ICU monitoring (in particular of the...

Ngày tải lên: 21/06/2014, 03:20

... Ferrandis P., De las Heras J., Effects of high temperatures on Tree seed age and fire germination germination of Pinus halepensis Mill and pinaster Aiton subsp pinaster seeds in Southeast Spain, ... globulus were obtained from plantations in Galicia in the years 1990, 1991, 1992 and 1993 The fruit was collected and seeds obtained between the end of summer and the beginning of autumn The seeds ... W.R., Some effects of high temperatures on the cones and seeds of jack pine, For Sci (1960) 194–199 [3] Bell D.T., Interaction of fire, temperature and light in the germination response of 16 species...

Ngày tải lên: 08/08/2014, 14:21

... (MEX-SLEDAI index) significantly diminished in 90% of patients at days 60 and 90 of Rituximab therapy (Figure 1a) In all patients, the dose of glucocorticoids remained unchanged during the study, and in ... regarding the in vivo effect of Rituximab on regulatory cells and apoptosis of T lymphocytes are interesting and that its possible role in the putative effect of this biological agent in SLE ... activated in vitro with phytohemagglutinin (PHA) The percent of CD4+ lymphocytes synthesizing IL-10 was determined using the appropriate commercial kit (Miltenyi), following the instructions of the...

Ngày tải lên: 09/08/2014, 08:22

... NY) containing 10% (v/v) heat-inactivated fetal bovine serum (Gibco, Grand Island, NY), penicillin (100 U/mL) and streptomycin (100 mg/mL), and they were maintained in a 37°C humidified incubator ... Analysis of the data and plotting of the figures were performed with the aid of software (Origin Version 7.5 and SPSS Version 13.0) Results Expression of b1- and b2-adrenergic receptors in SGC7901 and ... lines, BGC-823 and SGC-7901, were established in the People’s Hospital of Peking University and China and No.6 Hospital of Shanghai, China, respectively These two human gastric cancer cell lines...

Ngày tải lên: 09/08/2014, 09:20

... role in triggering pain In addition, MMP1 and Figure Histological evaluation of the anti-inflammatory effects of piperine Paraffin sections of rat ankles were stained with hematoxylin and eosin ... Piperine also inhibited both the protein and mRNA expression levels of IL6 and COX-2 In particular, piperine inhibited the production of PGE2 more potently than the production of IL6 Interestingly, ... WDR of the hind paws in the normal group was 50:50 (data not shown), indicating that 50% of the weight was carried in each hind paw As the pain and swelling of the ankle progressed due to induction...

Ngày tải lên: 09/08/2014, 14:20

... syndrome: clinical and investigative findings in 14 subjects J Neurol Neurosurg Psychiatry 1992, 55:665-670 Tzischinsky O, Dagan Y, Lavie P: The effects of melatonin on the timing of sleep in patients ... baseline, while taking placebo, and while taking melatonin are shown in Tables and Subjective sleep onset latency (SOL) was 37.5 +/- 41.3 minutes at the baseline There was evidence of an effect of ... great deal of interest in whether properly timed melatonin administration can facilitate circadian phase shifting in these situations [28] Normally, production of melatonin by the pineal gland is...

Ngày tải lên: 10/08/2014, 09:20

... deposition in the surrounding area The nature and extent must be determined and evaluated using intake water quality data, design information and mathematical modeling The on-site gas turbine will ... include blowdown from clarifiers and cooling towers, drainage from equipment and floor areas, demineralizer wastes and sanitary wastes Contaminants in these streams are generally a function of ... was built and started-up in Buggenum, in the Netherlands, in 1994 Since October 2001, the installation has been owned and operated by NUON Power as a fully commercial electric generating unit...

Ngày tải lên: 10/08/2014, 20:20

... of testing effects of single chemicals, degradation products and mixtures External environmental effects must also be 280 EFFECTS OF CHEMICALS included as system parameters in evaluation of pollutant ... while promoting cigarette use abroad Cancer of the oral cavity in Asia is linked with chewing of tobacco leaves and betel nuts High incidence of gastric cancer in Chile, Iceland, and Japan has ... Dietary contamination with aflatoxin is thought to be a causitive effect of liver cancer in the Bantu Aflatoxin is a fungal carcinogen 278 EFFECTS OF CHEMICALS Ingestion of azoglucoside carcinogens...

Ngày tải lên: 10/08/2014, 20:20

... Page of Author details Shanghai Institute of Hematology, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China 2Inserm, U728, Pôle de Recherches Franco-Chinois, ... before and after temsirolimus showed the direct cytostatic effect of this mTOR inhibitor through cell cycle arrest, as demonstrated by down-regulation of cyclin D1 and Ki67 in lymphoma cells, and ... Along this line, tumor infarct and necrosis linked to tumor microvessel thrombi have been reported in xenografted pancreas and colon cancer treated by mTOR inhibitor [12] Reduction of microvessel...

Ngày tải lên: 10/08/2014, 22:21

... deployment, psychiatric problems including PTSD, and Page of misconduct outcomes The objectives of this study were to ascertain and compare incidence rates of three types of misconduct outcomes (demotions, ... severe instances of blatant criminal conduct In order to classify individuals into the appropriate deployment cohort, all outcomes included in the analyses had to have occurred after a deployment Information ... [10,14,36,38,39], both of which could explain the increased behavioral problems in the war-deployed cohort The finding of greatest concern in this study is that combat deployed Marines with a PTSD...

Ngày tải lên: 11/08/2014, 16:22

... value of changes in BMI and nadir SpO2 entered individually on the following outcomes: changes in insulin, insulin resistance as measured by HOMA-IR, leptin, ghrelin, adiponectin and resistin Inclusion ... for changes in weight, hormone levels and sleep parameters [r(pvalue)] HOMAIR BMI HOMAIR Ghrelin Leptin Insulin Adipon ectin Resistin Ghrelin Leptin Insulin Adiponectin nectin Resistin ESS CPAP ... http://respiratory-research.com/content/12/1/80 in its regulation including changes in insulin sensitivity Insulin administration has been shown to suppress circulating ghrelin levels in some [31] but not all studies [32] Plasma insulin...

Ngày tải lên: 12/08/2014, 13:22

... contained in 6-well plates Cells were seeded in RPMI medium containing 0.1% BSA and penicillin/streptomycin at a density of × 105 cells/ ml and incubated at 37°C, 5% CO2 for hour before washing ... cortical staining In accord with the role of calcium and ROS in the induction of IL-1 expression, both of these factors appeared to play an important role in modulating the F-actin cytoskeleton ... their increased pro-inflammatory effects by modulating intracellular calcium signalling in macrophages leading to expression of proinflammatory cytokines An additional consideration is the effects...

Ngày tải lên: 12/08/2014, 18:21

... period of days [12] The reported beneficial effects of EPO in preclinical models of shock, trauma and haemorrhage are exciting, but further studies are warranted to determine the effects of EPO ... injury/dysfunction and survival) in models of CLP Interestingly, in 86 patients admitted to a long-term acute care facility, administration of weekly recombinant human EPO (n = 42) resulted in ... reported in other models of disease [11] Thus, the beneficial effects of EPO in rodent models of endotoxaemia may vary with doses of EPO and LPS, as well as species (rat or mouse) used Interestingly,...

Ngày tải lên: 13/08/2014, 03:21