... analysis of third-party disseminationof labeling informationfromstudiesconductedunderBPCAand PREA, including both the speed ofdisseminationand the accuracy and completeness of the information ... ConductedUnderBPCAandPREA Conclusions SAFETY AND EFFICACY ASSESSMENTS IN STUDIESCONDUCTEDUNDERBPCAANDPREA Sources ofInformation About Safety and Efficacy Results in Pediatric Drug Studies ... pediatric studies; strengthen pediatricstudies requested underBPCA or required under PREA; address areas of limited pediatric investigation underBPCAand PREA; including neonatal studies and...
... celecoxib and NSAIDs, and we chose to perform two analyses: comparisons of all doses of celecoxib with all doses of NSAIDs, and between licensed daily doses of celecoxib and licensed doses of NSAIDs ... discontinuation because of adverse events or lack of efficacy This systematic review and meta-analysis of celecoxib in osteoarthritis and rheumatoid arthritis was conducted using informationfrom company ... trials of 12 weeks' duration, 46% of doses were 200 mg and 46% were of 400 mg daily In trials of 24 weeks or longer, 92% of doses were of 800 mg daily Longerlasting trials used higher doses of celecoxib...
... cluster randomised controlled trial of the Effect of 'Active DisseminationofInformation' on standards of care for premature babies in England (The BEADI Study) will be clinicians from neonatal ... CEMACH central and regional offices teams that helped in the organisation and support for the study and the project steering group and in particular Professor Andrew Wilkinson and Professor Kate ... nal and Child Health Project 27/28: inquiry into quality of neonatal care and its effect on the survival of infants who were born at 27 and 28 weeks in England, Wales, and Northern Ireland Pediatrics...
... cluster randomised controlled trial of the Effect of 'Active DisseminationofInformation' on standards of care for premature babies in England (The BEADI Study) will be clinicians from neonatal ... CEMACH central and regional offices teams that helped in the organisation and support for the study and the project steering group and in particular Professor Andrew Wilkinson and Professor Kate ... nal and Child Health Project 27/28: inquiry into quality of neonatal care and its effect on the survival of infants who were born at 27 and 28 weeks in England, Wales, and Northern Ireland Pediatrics...
... stress and autophagy induction between synovial fibroblasts from rheumatoid arthritis and those from osteoarthritis Materials and methods Cell cultures Synovial fibroblasts were isolated from surgical ... experiments and autophagy mechanism studies DK and GL carried out cell viability experiments WY participated in the design of the study and provided fibroblasts YK, JC, YL, SP, SJ, SC and HRK contributed ... Microphotographs of GFP-LC3 fluorescence were obtained with a fluorescence microscope The detection of punctuated staining of GFP-LC3 from diffuse staining indicated the formation of autophagosomes...
... Combining informationfrom surveys of several species to estimate the probability of freedom from Echinococcus multilocularis in Sweden, Finland and mainland Norway Acta Veterinaria Scandinavica ... Sweden, Finland and mainland Norway The number of animals, number of species and types of tests included in the surveillance differ between countries Wahlström et al Acta Veterinaria Scandinavica ... introduction of an infected dog excreting eggs (Table 3) The estimated total number of dogs in Norway and Finland are approximately 50% and 75%, respectively, of the Swedish populations and the number of...
... MALDI-TOF spectra of peak (0.2 M-eluted) from the FFD-500 group (A) and its respective MALDI-TOF MS ⁄ MS spectra (B) All other details are as in the legends to Figs and the addition of same amount of ... MALDI-TOF MS ⁄ MS analysis for structural elucidation as detailed in the Materials and Methods MALDI-TOF spectra of peak (0.2 M-eluted) from the SFC group (A) and its respective MALDI-TOF MS ⁄ ... for 22 and 35% of total carbohydrate content in SFC and SFD groups, respectively Purification of 2AA-labeled oligosaccharides from different experimental groups The low yield of laminin from rat...
... the impact of muscle fatigue on dynamic postural control under single and dual-task conditions in young and older adults Thus, the objectives of this study were to examine the effects of knee extensor/flexor ... fatigue, as established by standard criteria, on gait characteristics under single and dual-task conditions in young and older adults and to find out the impact of muscle fatigue on dual-task ... on the results ofstudiesconducted by Granacher et al [6], Helbostad et al [8], and Vuillerme et al [10], we hypothesized that localized muscle fatigue of the knee extensors and flexors results...
... layer of subsoil composed of gravel and sand sediments of quaternary origin laying above impermeable clay sediments of tertiary origin The forest stand was composed of oak (Quercus robur L., 78% of ... the model tree (V T.tree) andof the stand (VT.stand) at the area of Astand Atree = Astand (VT.tree / VT.stand) crown ground plan, Actmax or similarly by the ground plan of root systems, Artmax, ... RESULTS AND DISCUSSION 3.1 Actual stand water balance under ample underground water supply Under non-limiting underground water supply, the level of underground water was within the upper layer of...
... [23] contain data from many chips, with the goal of gaining informationfrom pooling data GEO currently has thousands of chips, with a heavy skewing towards Affymetrix MG-U74Av2 and HG-U95 chips ... mean and trimmed variance of each chip and using percentage ranks instead of numerical expression levels In the first case, all of the data points were adjusted to align the mean and variance of ... 75% of the value of the lower rank (nearer the top of the list) with 25% of the value of the higher rank A final score was obtained by combining the results from each method in this way, and...
... blogs from a blog database, and extracting travel informationfrom them In the identification of travel blogs, we obtained of 38.1% for Recall and 86.7% for Precision In the extraction of travel information ... task of compiling travel information is divided into two steps: (1) identification of travel blogs and (2) extraction of travel informationfrom them We explain these steps in Sections 3.1 and ... names of local products or souvenirs, such as 'cake' or 'noodle' Experiments We conducted two experiments: (1) identification of travel blogs, and (2) extraction of travel informationfrom blogs...
... of analytical grade E D C B A Isolation of CS from cartilage and DS from lung CS was isolated from fresh articular and tracheal cartilages as previously described [4,5], and DS was isolated from ... AC and ABC lyases generate disaccharides and tetrasaccharides [4] and have been widely used for the analysis of CS ⁄ DS composition These studies have yielded crucial data allowing an understanding ... disaccharides and tetrasaccharides from CS ⁄ DS [16], and Sugahara et al [21] have examined, by 1H NMR and MS, a series of chondroitin ABC lyase-resistant fragments derived from CS or DS Several of these...
... result of a lack of distinction among terms and the lack of a one-to-one mapping between terms and concepts, especially at the highest levels of the hierarchy 3.1 I n c o m p l e t e information ... this information is provided in the definition of cutlery: cutlery implements used for eating SUCII AS knives, forks, and spoons ICED] The extraction ofinformationfrom differentiae demands ... hierarchies One of the most promising strategies for refining extracted information is the Use ofinformationfrom several dictionaries Hierarchies derived from individual dictionaries suffer from incompleteness,...
... sentences randomly from the sentences to which both annotators gave the same marking and same evaluation To determine the reliability of the annotators' judgment and the difficulty of the task, ... may often be used with determiners in the general domain Hosaka, Junko and Umetsu, Ryo 2002 Toward the extraction of protein-protein interaction informationfrom immunology literature Proc of ... phrases The matrix shown in Table defines three combinations of gold standard and system extraction results, A, B, and C: A B C Gold Standard extracted extracted not extracted System extracted not...
... http://www.jneuroengrehab.com/content/8/1/53 Page of 10 The aim of our study was to increase the understanding of the basic mechanisms, as well as of the possibilities and limits of this approach, by processing ... relative spike rates of each waveform w.r.t the others This should prevent classification of the motor commands based on the “quantity of activity” and favor the use of the “quality of activity” intended ... commands) of it This strategy would allow an easier, more efficacious and faster (namely online) control of a dexterous hand prosthesis In fact, this could increase the number of motor commands...
... restnoise from cuff recorded neural signals in cats as well as in humans However, the main goal of these studies was to identify the onset (and offset) of a specific neural activity, with the aim of ... filtered (band pass filter with cutoff frequencies of 10 Hz and kHz), digitized at 20 kHz (PowerLab) and fed into a PC running Chart v5.5 (AD Instruments) Datasets consisted of ten applications of every ... first and testing on the second half of the data (A) Training procedure consisting of: Filtering (in order to eliminate the EMG low band, and amplifiers high band noise); Feature extraction from...
... radius, and H (1) and H (2) are the derivatives of the Hankel functions with respect to kR Q(1) and Q(2) are the expansion coefficients of the incoming and outgoing wave fields in terms of cylindrical ... Detail of the measured data set of Figure 4, (b) reconstruction of the response of the first-order ceiling reflection using the Radon transform method, (c) the result of subtracting (b) from (a) ... Conservatory of Music in The Hague, at the Department of “Art of Sound.” During the summer semester of 2001, he fulfilled the “Edgard Varese” guest professorship at TU Berlin In 2004, he held a Guest Professor...