disorders of the peripheral nervous system
báo cáo khoa học: "Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature" pdf
Ngày tải lên :
09/08/2014, 02:20
... angiitis of the central nervous system: serial MRI of brain and spinal cord Neuroradiology 2001, 43:599-607 14 Moore PM: Diagnosis and management of isolated angiitis of the central nervous system ... Angiitis of the Central Nervous System: a Case Report and Review CNS Spectrums 2008, 13:209-213 Page of 10 Ozawa T, Sasaki O, Sorimachi T, Tanaka R: Primary angiitis of the central nervous system: ... presentation of primary angiitis of the central nervous system Ann Rheum Dis 2008, 67:1732-1735 doi:10.1186/1477-7819-9-97 Cite this article as: You et al.: Isolated angiitis of the central nervous system...
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báo cáo hóa học: " Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE" pptx
Ngày tải lên :
19/06/2014, 22:20
... that the lack of CCR5 does not protect from MS, but rather it may predispose to the chronic course of the disease [69] This would further imply that in view of the redundancy in the chemokine system, ... immunoneutralization of CCL3 [44], DNA vaccination [45], or genomic deletion of the CCR1 gene [22], reduces clinical disease Taken together, the results of the present study and from previous ones on the role of ... knock-out of CCR5 in humans per se confers no protection from MS, and the lack of effect of CCL3 deficiency in mice [67] illustrates redundancy in the chemokine system Although some of the data on the...
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Báo cáo sinh học: "The long term effects of chemotherapy on the central nervous system" docx
Ngày tải lên :
06/08/2014, 18:21
... vulnerable, population of patients Chemotherapy-induced cognitive decline in the absence of radiation The best data on the cognitive effects of chemotherapy alone have come from studies of children with ... are planned that further reduce the dose of craniospinal radiation to 1,800 cGy, virtually no attention has been paid to the possible contribution of the chemotherapy to the cognitive decline ... tumors, especially for the very young Because of the rapid myelinization that occurs in infants, the finding by Noble and colleagues [1] of the adverse effects of chemotherapy on oligodendrocytes...
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Báo cáo sinh học: "Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system" doc
Ngày tải lên :
06/08/2014, 18:21
... at the month time point, along with markedly decreased levels of MBP in the CC and in the white-matter tracts of the striatum of treated animals (Figure 10) In agreement with the majority of the ... nuclei; the distribution, morphology and size of these nuclei resembled those of the microvasculature endothelial cells of the CNS (Figure 11c-e) Double-labeling to visualize expression of Journal of ... contribute to the effects of chemotherapy on cognition The ability of irradiation to the CNS to suppress the generation of new neurons in the hippocampus has been suggested to be relevant to the understanding...
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Báo cáo khoa học: "Immunohistochemical study of constitutive neuronal and inducible nitric oxide synthase in the central nervous system of goat with natural listeriosis" potx
Ngày tải lên :
07/08/2014, 14:23
... is the first study of NOS expression in the goat brain with listeriosis The involvement of iNOS in bovine and caprine listeriosis has been reported previously, and the increased expression of ... Magnification A and B, ×66 C and D, ×132 Immunohistochmical study of nitric oxide synthase in the central nervous system of goat Enhanced expression of nNOS and iNOS in L monocytogenes-infected brain At ... were found in the neuronal processes Both nNOS and iNOS immunoreactivity were found in a proportion of the neurons in the brainstem and the staining pattern was similar to those of control brains...
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báo cáo khoa học: "In vivo observation of gold nanoparticles in the central nervous system of Blaberus discoidalis" potx
Ngày tải lên :
11/08/2014, 00:22
... known that the nanoparticles will interact with the proteins present in the biological system, i.e the material surrounding the nanoparticles are proteins present in the nervous system of the cockroach ... This correlation of activity and the effect of the nAuNPs on the CNS of the insect are due to how the brain of the cockroach controls its muscle response and locomotion [6] There is a significant ... in weather affect the activity of both groups The effects of these variables are diminished by presenting the activity ratio of the treated to the untreated group Although the treated/untreated...
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ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 1 pps
Ngày tải lên :
11/08/2014, 06:21
... physiology of the ear and the nervous system The book also provides a comprehensive coverage of disorders of the auditory system emphasizing the interaction between pathologies of the middle ear and the ... and their diagnosis Because of the complexity of many disorders of the auditory system the clinician must have a thorough understanding of the basic functions of the entire auditory system and the ... divide disorders of the auditory system in to peripheral and central disorders This book therefore takes an integrated approach to disorders of the auditory system While most disorders of the auditory...
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ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 2 ppsx
Ngày tải lên :
11/08/2014, 06:21
... at the entrance of the ear canal compared with the sound pressure that is measured in the place of the head The effect of the head on the sound at the entrance of the ear canal is related to the ... ratio between the effective area of the tympanic membrane and the area of the stapes footplate, but the lever ratio of the middle ear bones also contributes The ratio of areas of the BOX 2.2 SOUND ... remarkable in the light of the FIGURE 2.12 (A) Average displacements of the umbo, the head of the stapes and the lenticular process of the incus (B) The lever ratio at 124 dB SPL at the tympanic...
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ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 4 potx
Ngày tải lên :
11/08/2014, 06:21
... target of the classical pathways Another pathway from the IC to the primary cortex is via the posterior nucleus of the thalamus that sends axons to the AAF The neurons of the medial division of the ... parts of the MGB of the thalamus, the nonclassical sensory pathways use the dorsal and medial division of the MGB as relay (Fig 5.10) [122] These divisions of the MGB receive their input from the ... of the fourth ventricle (Fig 5.15B) [72] The other part of the olivocochlear system projects mainly to the contralateral cochlea and the fibers of that system travel deeper in the brainstem The...
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ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 6 pot
Ngày tải lên :
11/08/2014, 06:21
... difference between the latency of the N1 of the AP and that of the response from the intracranial portion of the auditory nerve is the travel time in the auditory nerve from the ear to the recording ... portion of the floor of the lateral recess is the (dorsal) surface of the dorsal cochlear nucleus and the rostral portion of the floor of the lateral recess is the dorsal surface of the ventral cochlear ... peak I of the ABR occurs with the same latency as the negative peak (N1) in the ECoG [233] The N1 peak of the ECoG is generated by the most peripheral portion of the auditory nerve and therefore...
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ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 7 pot
Ngày tải lên :
11/08/2014, 06:21
... standard error of the mean are shown as a function of the intensity of the noise The TTS was measured 20 s after the end of the exposure In this study the noise exposure consisted of a band of noise, ... examples of morphological changes in the auditory nervous system Speech discrimination can be predicted relatively well on the basis of the elevation of the hearing threshold in disorders of the middle ... a sound (turning the volume of a loudspeaker down) Many forms of disorders of the conductive apparatus will resolve on their own, as they often in the case of otitis media, or they can be successfully...
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ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 8 docx
Ngày tải lên :
11/08/2014, 06:21
... reaches the cochlear nucleus The growth of the amplitude of the reflex response is reduced in 242 Section III Disorders of the Auditory System and Their Pathophysiology FIGURE 9.27 The growth of the ... selectivity of the ear (cf Chapter 3) The widening of the tuning of the basilar membrane broadens the “slices” of the spectrum of broad band sounds from which the cochlea provides information to the ... Section III Disorders of the Auditory System and Their Pathophysiology 7.1 Disorders of the Brainstem Auditory Pathways Disorders that affect the brainstem nuclei of the auditory system and which...
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ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 9 pdf
Ngày tải lên :
11/08/2014, 06:21
... to the classical auditory nervous system, thus a sign of re-organization of the nervous system 10 Severe tinnitus is often accompanied by abnormal interaction between the auditory system and other ... phonophobia) are some of the most diverse and complex disorders of the auditory system and their causes are often obscure Often it is not even possible to identify the anatomical location of the physiological ... location of the generation of the tinnitus The injury from the tumor to the auditory nerve may over time have caused changes in neural 258 Section III Disorders of the Auditory System and Their...
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The role of hydrogen sulfide in the central nervous system implications in the treatment of alzheimers disease
Ngày tải lên :
09/09/2015, 08:17
... Clinical symptoms and the course of the illness The main cognitive symptoms of AD are amnesia, aphasia, apraxia, agnosia, and executive dysfunction Over the course of the illness these symptoms become ... common mechanisms of action of these drugs are the inhibition of the rate limiting steps of Aβ generation i.e β- and/or γ- secretases processing of APP (Citron, 2010) Although the reasoning behind ... the neurons The research group detected the significant presence of H2S in the brain homogenate preparation of CBS-/- mice (Shibuya et al., 2009) Kimura further observed that 3-MST acts together...
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Genetic engineering and surface modification of baculovirus derived vectors for improved gene delivery to the central nervous system
Ngày tải lên :
14/09/2015, 11:28
... low efficiency of non-viral gene delivery remains a critical drawback of the system On the other hand, viral gene delivery systems are favoured because of the high efficiency of infective viral ... member of the retrovirus family The main advantage of lentivirus-based vectors is their ability to integrate into the host genome of both dividing and nondividing cells, thereby providing the potential ... spite of rapid advancement of biomedical science and technology, a number of complicated diseases still remain incurable Many of these unconquered diseases such as Central Nervous System (CNS) disorders, ...
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A study of the recombination activating gene 1 in the zebrafish nervous system
Ngày tải lên :
15/09/2015, 17:09
... nervous system 13 1.2.1 The expression of Rag genes in the nervous system 13 1.2.2 A brief overview of the nervous system 16 1.2.3 Questions about the neuronal function of Rag1 17 1.3 Advantages of ... 2001) These data indicate that the expression of Rag1 in the nervous system is conserved among vertebrate species and suggest a function 1.2.2 A brief overview of the nervous system The nervous system ... According to these functions, the nervous system is categorized as sensory system, integrating system and motor system respectively (Delcomyn, 1998) The structural organization of the nervous system...
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Development of hybrid promoters and viral vectors for improved gene delivery to the central nervous system
Ngày tải lên :
16/09/2015, 08:30
... one of the key issues of gene therapy The expression level and specificity of the therapeutic gene is primarily determined by the activity of the promoter at the transcriptional level, and the ... in the nervous system, carrying out the fundamental tasks of receiving, conducting and transmitting signals Therapeutic protection of these cells is one of the main goals of gene therapy of neurological ... issue of gene therapy The tropism of the vector can essentially determine the cell type-specificity of the transgene expression at the transductional level, and the transduction efficiency of the...
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Specificity and diversity in the vertebrate nervous system an analysis of two genes
Ngày tải lên :
16/09/2015, 08:31
... help in the study of the role of EphrinB2 in vivo EphrinB2 expression has been detected in the visual system in other organisms The aim of this project was to study the expression pattern of EphrinB2 ... al., 1967) At least at the molecular level there seems to be a link between the immune system and the nervous system Rag1 plays a key role in the initiation of this process of genomic rearrangement ... With the help of mutants and other tools of genetic manipulation, the mechanisms of neural differentiation and nervous system patterning have been elucidated As proposed by Goodman and Doe, the...
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INVESTIGATION OF MEMBRANE PROPERTIES IN THE CENTRAL NERVOUS SYSTEM OF DROSOPHILA MELANOGASTER STUDIED BY FLUORESCENCE CORRELATION SPECTROSCOPY
Ngày tải lên :
12/10/2015, 17:36
... onto the cover glass beside the sticky tape, with the help of a second blunt needle The embryo was not lifted above the surface of the dissecting medium, as this caused dispersion of the tissue The ... and is the excitation intensity of the laser at the centre of the laser π wo beam with laser power P wo and zo are the radial and axial distances of the laser focus, respectively, at which the fluorescence ... introduction of the model organism, Drosophila melanogaster, is also given Chapter introduces the concepts and theory of FCS as well as the experimental setup of this instrument The calibration of the...
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