disorders of platelets ppt

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

... spleen enlarges. Platelets are physiologically very Chapter 109. Disorders of Platelets and Vessel Wall (Part 1) Harrison's Internal Medicine > Chapter 109. Disorders of Platelets and ... and influence the environment of the forming clot. During platelet aggregation, additional platelets are recruited to the site of injury, leading to the formation of an occlusive platelet thrombus. ... TPO, which then stimulates platelet production. Platelets circulate with an average life span of 7–10 days. Approximately one-third of the platelets reside in the spleen, and this number...

Ngày tải lên: 07/07/2014, 04:20

... decreased platelets in microangiopathic hemolytic anemia. Chapter 109. Disorders of Platelets and Vessel Wall (Part 2) Thrombocytopenia Thrombocytopenia results from one or more of three ... tube), or ideally a smear of freshly obtained unanticoagulated blood, such as from a finger stick, can be examined. Figure 109-1 Photomicrographs of peripheral blood smears. ... sequestration, usually in an enlarged spleen; and/or (3) increased platelet destruction. Disorders of production may be either inherited or acquired. In evaluating a patient with thrombocytopenia,...

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

... acid. Values are the means ± SD of duplicate samples of three independent experiments. Total c.p.m., 6000–25 000. Fig. 4. Distribution of the radioactivity of the platelets (A) and the extracellular ... radioactivity of platelets and extracellular space was measured. Values are the means ± SD of duplicate samples of three independent experiments. Total c.p.m., 15 000–45 000. Fig. 6. Distribution of the ... 0.82% NaCl (w/v). Preparation of washed rabbit platelets Blood was drawn from the central vein of the ear of male rabbits and was collected into an ACD anticoagulant solution. Platelets were washed as...

Ngày tải lên: 08/03/2014, 08:20

Ngày tải lên: 15/03/2014, 01:20

... substance of the optic nerve head (Fig. 29-13). They are unrelated to drusen of the retina, which occur in age-related macular degeneration. Optic disc drusen are most common in people of northern ... nerve develops atrophy. In this setting, reduction of optic disc swelling is an ominous sign of a dying nerve rather than an encouraging indication of resolving papilledema. Figure 29-12 Papilledema ... cerebrospinal fluid, points by exclusion to the diagnosis of pseudotumor cerebri (idiopathic intracranial hypertension). The majority of patients are young, female, and obese. Treatment with...

Ngày tải lên: 06/07/2014, 15:21

... weakness), or a family history of ptosis should be sought. Fluctuating ptosis that worsens late in the day is typical of myasthenia gravis. Chapter 029. Disorders of the Eye (Part 18) Orbital ... leukocytosis. It often arises from the paranasal sinuses, especially by contiguous spread of infection from the ethmoid sinus through the lamina papyracea of the medial orbit. A history of recent ... develop so gradually that the patient is unaware of the problem. Inspection of old photographs is helpful in dating the onset. A history of prior trauma, eye surgery, contact lens use, diplopia,...

Ngày tải lên: 06/07/2014, 15:21

... compression. In cerebral herniation the nerve becomes trapped between the edge of the tentorium and the uncus of the temporal lobe. Oculomotor palsy can also occur from midbrain torsion and ... metastasis), herpes zoster infection, and the Tolosa-Hunt syndrome. The etiology of an isolated, pupil-sparing oculomotor palsy often remains an enigma, even after neuroimaging and extensive laboratory ... thought to result from microvascular infarction of the nerve, somewhere along its course from the brainstem to the orbit. Usually the patient complains of pain. Diabetes, hypertension, and vascular...

Ngày tải lên: 06/07/2014, 15:21

... examination of the eyes. Observation of nystagmoid movements of the optic disc on ophthalmoscopy is a sensitive way to detect subtle nystagmus. Gaze-Evoked Nystagmus This is the most common form of ... The pattern of nystagmus may vary with gaze position. Some patients will be oblivious to their nystagmus. Others will complain of blurred vision, or a subjective, to-and-fro movement of the environment ... appear until several months of age. Congenital motor nystagmus, which looks similar to congenital sensory nystagmus, develops in the absence of any abnormality of the sensory visual system....

Ngày tải lên: 06/07/2014, 15:21

... Chapter 030. Disorders of Smell, Taste, and Hearing (Part 2) Disorders of the Sense of Smell These are caused by conditions that interfere with the access of the odorant to the ... differentiate these different types of olfactory losses. Fortunately, the history of the disease provides important clues to the cause. The leading causes of olfactory disorders are summarized in Table ... Meningiomas of the inferior frontal region are the most frequent neoplastic cause of anosmia; loss of smell may be the only neurologic abnormality. Rarely, anosmia can occur with gliomas of the...

Ngày tải lên: 06/07/2014, 15:21

... Chapter 030. Disorders of Smell, Taste, and Hearing (Part 5) Disorders of the Sense of Taste Disorders of the sense of taste are caused by conditions that interfere with the access of the tastant ... agents; radiation therapy A side effect of medication is the single most common cause of taste dysfunction in clinical practice. Xerostomia, regardless of the etiology, can be associated with ... complaints. Xerostomia, the use of antibiotics or glucocorticoids, or immunodeficiency can lead to overgrowth of Candida; overgrowth alone, without thrush or overt signs of infection, can be associated...

Ngày tải lên: 06/07/2014, 15:21

... denervation of the iris sphincter the pupil does not respond well to light, but the response to near is often relatively intact. When the near stimulus is Chapter 029. Disorders of the Eye ... varies. Anisocoria that increases in dim light indicates a sympathetic paresis of the iris dilator muscle. The triad of miosis with ipsilateral ptosis and anhidrosis constitutes Horner's ... by holding a penlight directly in front of the patient at about 1 m. If the eyes are straight, the corneal light reflex will be centered in the middle of each pupil. To test eye alignment more...

Ngày tải lên: 06/07/2014, 15:21