... from human and the narrow-leafed lupin. ppCH 2 ppA and pCH 2 pppA, inhibited the human enzyme with K i val- ues of 1.6 and 2.3 nm, respectively, and the lupin enzyme with K i values of 30 and 34 ... calculated according to the method of Dixon and Webb [46] from the slopes of plots v ⁄ v i against [I] (where v and v i are velocities in the absence and presence of inhibitor, respectively, and [I] is the inhibitor ... Methylene analogues of adenosine 5Â-tetraphosphate Their chemical synthesis and recognition by human and plant mononucleoside tetraphosphatases and dinucleoside tetraphosphatases Andrzej Guranowski 1 ,El _ zbieta...
Ngày tải lên: 16/03/2014, 14:20
Ngày tải lên: 26/11/2013, 13:25
the method of investment appraisal which may be applied to evaluated and rank potential investment opportunities and their relative merits and limitations
... potential investment opportunities and their merits and limitation. Moreover, the nature of gearing and potential effected of high gearing on perceived risk and cost of capital. 2 IRR (A) =10%+ %05.12 150,81$950,20$ %)10%20(*250,20$ = −− −− IRR ... in the terms and 12 at 10% and the second one is company B with NPV of $ 57,500. IRR of company C is the highest of 21.86 %, then the second higher is company B with IRR of 18.46% and the lowest ... bottom line of their investment. ã Economy of scale. According to Ansof (1971), acquisitions were in general unprofitable, as they did not contribute to increase in all of the variables of companies’...
Ngày tải lên: 17/02/2014, 13:02
Báo cáo Y học: Properties of group I allergens from grass pollen and their relation to cathepsin B, a member of the C1 family of cysteine proteinases pdf
... numbered. Areas of high similarity exist around Cys69 and Cys72 and around Trp186, Trp193 and Trp197. The positions of Cys41, 57, 69 and 72 are especially conserved between b-expansins and cathepsin ... in CP2 of G. lamblia. Fig. 2. Comparison of the expression and enzymatic activity of recom- binant Phl p 1 N and Q. Sizes in kDa are indicated. (A) P. pastoris expression of Phl p 1 N (N) and Phl ... Properties of group I allergens from grass pollen and their relation to cathepsin B, a member of the C1 family of cysteine proteinases Kay Grobe 1 , Marco Poă ppelmann 2 , Wolf-Meinhard Becker 2 and...
Ngày tải lên: 08/03/2014, 22:20
The Effects of Land Use on the Mobility of Elderly and Disabled and Their Homecare Workers, and the Effects of Care on Client Mobility: Findings from Contra Costa, California pdf
... Transportation Efficiency Act of 1991 ii Abstract The Effects of Land Use on the Mobility of Elderly and Disabled and Their Homecare Workers, and the Effects of Care on Client Mobility: ... (TAZ) and zip code. Note. Based on Metropolitan Transportation Commission (MTC) data i The Effects of Land Use on the Mobility of Elderly and Disabled and Their Homecare Workers, and ... habits and needs of consumers and providers, and the extent of care consumers received. The six interrelated hypotheses predicted that, given the income constraints of both populations and the...
Ngày tải lên: 14/03/2014, 17:20
Báo cáo khoa học: Enzymes of mannitol metabolism in the human pathogenic fungusAspergillus fumigatus– kinetic properties of mannitol-1-phosphate 5-dehydrogenase and mannitol 2-dehydrogenase, and their physiological implications pot
... order of magnitude below the s H of AfM1PDH. Discussion Kinetic mechanism of Af M1PDH and Af M2DH The theory developed by Cook and Cleland is used to deduce the kinetic mechanism of AfM1PDH and AfM2DH ... binding of Man-ol1P and NAD + by AfM1PDH is not ordered, and that there is also randomness in the binding of substrate and coen- zyme in each direction of the reaction catalyzed by AfM2DH. By way of ... also reported random binding of NAD + and Man-ol1P [29]. It is reasonable to assume that random binding of reactants by AfM1PDH and AfM2DH occurs in rapid equilibrium, and the absence of curvature...
Ngày tải lên: 14/03/2014, 23:20
Báo cáo khoa học: Platination of telomeric sequences and nuclease hypersensitive elements of human c-myc and PDGF-A promoters and their ability to form G-quadruplexes Viktor Viglasky potx
... Platination of telomeric sequences and nuclease hypersensitive elements of human c-myc and PDGF-A promoters and their ability to form G-quadruplexes Viktor Viglasky Department of Biochemistry, Faculty of ... to bind within each guanine, to form intrastrand and interstrand bifunctional and monofunctional adducts, etc. Some of the proposed binding places of studied oligomers possessing a high affinity ... using a quartz cell of 1 mm optical path length and an instrument scanning speed of 100 nmặmin )1 , with a response time of 2 s, over a wave- length range of 220–320 nm. The scan of the buffer alone was...
Ngày tải lên: 23/03/2014, 06:20
Báo cáo khoa học: Identification of proNeuropeptide FFA peptides processed in neuronal and non-neuronal cells and in nervous tissue potx
... (Clontech) and sequenced on both strands. Tissue extraction Mouse spinal cord tissue. Animals were handled in accordance with standard ethical guidelines (NIH Guide for Care and Use of Laboratory ... fmol of synthetic SQA-NPFF (A), at m/z 684.5 from HPLC fractions of NPFF-IR peak 2 (B), at m/z 990.0 from 100 fmol of synthetic hNPAF (D) and at m/z 990.0 from HPLC fractions of NPFF-IR peak3(E)andMS/MSspectraofthe[M+2H] 2+ precursor ... highly selective radioligands revealed the localization of both receptors in central nervous areas implicated in pain transmission [27]. The existence of two peptidergic systems of neurotransmission, mediated...
Ngày tải lên: 31/03/2014, 07:20
Báo cáo hóa học: " Quality of Life as reported by school children and their parents: a cross-sectional survey" docx
... psychiatry, and the KINDL for more extensive and broad assessment of QoL in children. The primary aims of the study were to compare child and parent by proxy ratings of child QoL and to investigate factors ... significant impact of parent and child gender in regard to agreement in ratings of child QoL was found. Both the child and par- ent by proxy versions of the Norwegian translations of the KINDL and ILC can ... explored possible cluster effects. The results of an analysis of unconditional random effects showed that only 3.6% of the total variance of the ILC LQ0-28 scores and 6.5% of the total KINDL Total QoL scores...
Ngày tải lên: 18/06/2014, 22:20
báo cáo hóa học: " Leader (L) and L* proteins of Theiler''''s murine encephalomyelitis virus (TMEV) and their regulation of the virus'''' biological activities" docx
... could trigger a cascade of immune system, leading to immune-mediated demyelination. Conclusion Both DA and GDVII subgroup strains of TMEV synthesize L, which consists of 76 AA and is processed from ... pitfall of L* in studies such as these involving L* is that the sequence of L* overlaps with that of polyprotein (L and a part of P1). Therefore, it is impossible to evaluate the role of L* with- out ... Central Page 1 of 8 (page number not for citation purposes) Journal of Neuroinflammation Open Access Review Leader (L) and L* proteins of Theiler's murine encephalomyelitis virus (TMEV) and their...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo hóa học: " On the Geometrical Characteristics of Three-Dimensional Wireless Ad Hoc Networks and Their Applications" pptx
... framework of random graph. Nodes and links of a net- workareconsideredasverticesandedgesofarandomgraph G(V,E), respectively, w here V is the set of vertices, each with a random location, and E is ... value of node degree, including that of the source and that of the ter- minal. Thus, it is easy to understand that k(R)isnogreater than F(R). In fact, for any two positive random variables x and ... normalized m ax-flow capacity of networks in the cuboid spaces, (a) 1 ì 1 ì 1, (b) 1 ì 1 ì 5, and (c) 0.5 ì1 ì 2. randomly chosen in each random graph, and the algorithm of the C++ program follows...
Ngày tải lên: 22/06/2014, 22:20
Báo cáo lâm nghiệp: "Small mammals of a forest reserve and adjacent stands of the Kelečská pahorkatina Upland (Czech Republic) and their effect on forest dynamics" pps
... stand and a certain level of resistance to the impact of small rodents in spite of unfavourable years of the total disposal of seed crop. In addition to the eff ect of small mammals on stands ... 50–58 Small mammals of a forest reserve and adjacent stands of the Kelečská pahorkatina Upland (Czech Republic) and their eff ect on forest dynamics J. S, J. U Faculty of Forestry and Wood ... higher species and structural diversi- ty of trees and microbiotopes limiting the ecologi- cal niche of Apodemus fl avicollis and allowing the occurrence of a number of other species of small mammals...
Ngày tải lên: 07/08/2014, 10:21
Báo cáo khoa học: "Genetic transformation: short review of methods and their applications, results and perspectives for forest trees" ppt
Ngày tải lên: 08/08/2014, 23:22
Homo-binding character of LMO2 isoforms and their both synergic and antagonistic functions in regulating hematopoietic-related target genes potx
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Conserved epitopes of influenza A virus inducing protective immunity and their prospects for universal vaccine development" doc
Ngày tải lên: 12/08/2014, 02:20
Báo cáo khoa học: " Detection and quantification of pestivirus in experimentally infected pregnant ewes and their progeny" pps
Ngày tải lên: 12/08/2014, 04:20
Báo cáo y học: "The Syndrome of Frontonasal Dysplasia, Callosal Agenesis, Basal Encephalocele, and Eye Anomalies – Phenotypic and Aetiologica"
... 34-42 41 Figure 7: Clinical and image aspects of patient 7 Figure 8: Clinical and image aspects of patient 8 Figure 9: Clinical and image aspects of patient 9 Int. J. Med. ... hallmark of several syndromes involving the frontonasal process that includes: isolated frontonasal dysplasia (MIM 136760 and 305645), acrofrontofacionasal dysostosis 1 (MIM 201180), acrofrontofacionasal ... spectrum of some sporadic mendelian, and chromosomal syndromes [14; 15; 16; 17; 18; 19]. It is remarkable that in spite of central nervous system damage, mental status is usually normal, and only...
Ngày tải lên: 03/11/2012, 10:05