diseases in humans and animals
EUTHANASIA – THE “GOOD DEATH” CONTROVERSY IN HUMANS AND ANIMALS pot
... discriminate between the intentional shortening of life as a by-product of the pain therapy (administration of opiates such as morphine), inducing terminal sedation, terminating of life (e.g by administration ... “cripples” and other “unfit” persons and arguing that the doctrine of evolution justifies shortening the lives of suffering people (Vanderpool, 2004) Euthanasia and medicine in the 19th and 20th ... the overpopulation of animals In veterinary medicine euthanasia is routinely XI XII Preface used in the form of killing out of kindness severely injured and/ or seriously sick animals To not euthanatize...
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harvard university press good natured the origins of right and wrong in humans and other animals mar 1996
... silent, staring closely at Mai's behind, some of them carefully poking a finger at it and then smelling their finger Mai was standing half upright, with her legs slightly apart, holding one hand between ... few dominant matriarchs and their families; the other included subordinate matriarchs and their families Being of low rank, Mozu and her offspring ended up in the second division According to ... Printed in the United States of America Seventh printing, 2003 Library of Congress Cataloging -in- Publication Data Waal, F B M de (Frans B M.), Good Natured : the origins of right and wrong in humans...
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Tài liệu From Burden to “Best Buys”: Reducing the Economic Impact of Non-Communicable Diseases in Low- and Middle-Income Countries pdf
... Tax increases Smoke-free indoor workplaces and public places Health information and warnings Bans on tobacco advertising, promotion and sponsorship Scaling up action against noncommunicable diseases: ... average of US $25 in low-income countries, US$ 50 in lower middle-income countries and US$ 139 in upper middle-income countries By contrast, findings from the second study by the WHO indicate that ... per capita investment of under US$ in low-income countries, US$ 1.50 in lower middle-income and US$ in upper middleincome countries When considered in terms of overall health spending, these...
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Báo cáo khoa học: A mitochondrial cytochrome b mutation causing severe respiratory chain enzyme deficiency in humans and yeast doc
... highlighting the evolutionary conservation of this region of the protein, including the positively charged arginine at position 318 (shown in bold) and the two flanking amino acids (boxed) Interestingly, ... from several tissues including skeletal muscle, circulating lymphocytes and urinary epithelial cells by standard SDS ⁄ proteinase K digestion protocols and from hair shafts and individual muscle ... subunit and cytochrome b might be altered in the mutant, which may in turn perturb the dimer structure and ⁄ or ISP binding (Fig 5) A decrease in the rate of quinol oxidation may also be explained...
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Báo cáo khoa học: A novel glycogen-targeting subunit of protein phosphatase 1 that is regulated by insulin and shows differential tissue distribution in humans and rodents pdf
... Treatment of animals Diabetes was induced with either intravenous or intraperitoneal injection of streptozotocin into male Wistar rats and insulin was subsequently administered intravenously into some ... stores and GS activity in muscle, liver and adipose tissue Glucose intolerance, hyperinsulinaemia and insulin resistance were also observed to develop with increasing age These results indicate ... blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase Biochem J 305, 25–28 Ingebritsen TS, Foulkes...
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nuclear import and export in plants and animals - t. tzfira, vitaly citovsky
... The following gives an overview over the motifs mapped in different nuclear proteins, including transcription factors, DNA- and RNA-binding proteins, viral proteins, kinases, and kinase adapters ... transactivation domain, and a C-terminal steroid-binding domain While in these early studies the domain required for nuclear matrix attachment was localized to the C-terminal steroid binding domain in hAR, ... movement is determined by Ran, a small GTP-binding protein (reviewed in refs 22, 48 and 50) NPC structure includes soluble proteins, termed nucleoporins (nups) and integral membrane proteins, termed...
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Báo cáo sinh học: "Adaptive evolution of centromere proteins in plants and animals" ppt
... Characterization of internal DNA-binding and C-terminal dimerization domains of human centromere/kinetochore autoantigen CENP-C in vitro: role of DNA-binding and self-associating activities in kinetochore ... DNA is rapidly evolving in plants and animals, so adaptation of the major centromere DNAbinding proteins would maintain an interface with the conserved kinetochore machinery Indeed, regions of ... in regions that have been implicated in DNA binding [9,11] No positive selection was observed for the poorly mapped carboxy-terminal DNA-binding domain in our slidingwindow analysis, suggesting...
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Báo cáo y học: "Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates" docx
... disintegrin and metallopeptidase domain 1b chr8+:17371392-17373372 chr8-:39450156-39489335 Adam26B Adam3 a disintegrin and metallopeptidase domain 26B a disintegrin and metallopeptidase domain ... contains seven supplementary tables showing detailed results and datasets used in this study Abbreviations ADAM: a disintegrin and metallopeptidase domain; CDS: coding sequence; CTF: cardiotrophin; ... another indicates either gene gains in one or gene losses in the other In common with many other genomic features, genes in all species are in a state of flux during evolution However, since all...
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Báo cáo y học: "Vive la différence: biogenesis and evolution of microRNAs in plants and animals" ppt
... (siRNAs) As regulatory relationships are refined, the precision and phasing of hairpin processing may increase Shortening of the hairpin to produce a single defined duplex may represent a mature state ... animal protein-coding genes, including UTRs and coding sequences (CDSs) [51,52] Clustering of miRNA genes is more common in animals than in plants: up to 40% of miRNAs in Axtell MJ et al Genome ... 1b), which are pre-miRNA hairpins whose ends are defined by splicing instead of Drosha cleavage [55-57] Following their debranching into a linear form, they are diced into conventional miRNAs Mirtron...
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Báo cáo y học: "Responding to infectious diseases in Burma and her border regions" pptx
... the amphetamines produced in Asia and that seizures in her neighbors had increased in 2006[3] The future Infectious diseases in Burma and on her borders What have we learned from bringing together ... speakers from Thailand, China, India, and Bangladesh Examples of these challenges include the rising regional rates of MDR-TB and MDR-malaria For both India and Thailand, the provinces with the highest ... South and Southeast Asia: 25 January 2007: Bangkok Thailand Maung C: Mae Tao Clinic: a local solution for health services, training, and outreach At Responding to Infectious Diseases in the...
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Báo cáo y học: "Effect of Acute Administration of an Herbal Preparation on Blood Pressure and Heart Rate in Humans"
... treatment ingestion After eating, an increase in heart rate occurred in all three treatment groups The increase in heart rate does not coincide with the pharmacokinetics including blood levels and ... GJ Coronary spasm and thrombosis in a bodybuilder using a nutritional supplement containing synephrine, octopamine, tyramine and caffeine So African Med J 2008; 98: 372-373 Sander LC, Putzbach ... receptor binding It is well known that, in general, binding to α-adrenergic receptors results in vasoconstriction, with increased cardiovascular contractility and increased heart rate occurring in response...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 17)
... sampling until injection to GC, and from the standard solution to a test specimen) In principle, the sampling, extraction and GC analysis should be made at low temperature, in a gastight state and ... mg/mL), and kept airtightly in a refrigerator A 5-µL volume of the above solution is placed using a microsyringe in a glass vial containing mL of dimethyl sulfoxide (DMSO), capped airtightly and ... nitrite inhalant in rat and human blood: application for pharmacokinetic investigations J Chromatogr B 734:83–89 11) Kielbasa W, Fung HL (2000) Pharmacokinetics of a model organic nitrite inhalant and...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 67)
... eye mucosa and the skin results in its poisoning In the murder terrorism with VX taking place in Osaka, Japan, 1994, VX was sprayed on the back of the neck of the victim using a syringe (the exposure ... metabolism and decomposition in human bodies The detection limits of DAEMS in serum are about 50 ng/mL in the scan mode and about ng/mL in the SIM mode > Figure 2.3 shows a TIC, mass chromatograms and ... resulting acetonitrile layer is transferred to another test tube To the remaining aqueous phase, mL acetonitrile is again added, shaken and centrifuged The acetonitrile layers obtained are combined,...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 20)
... using benzene/n-hexane/diethylamine (25:10:1, v/v) as eluting solvent for getting each cannabinoid standard ∆9-THC, CBD and CBN are separately dissolved in ethanol to prepare 0.05–0.5 mg/mL standard ... factory worker was killed by being caught in a machine during working with it The concentrations of ∆9-THC-11-oic acid measured by GC/MS were 78 and 12 ng/mL in urine and blood, respectively; 0.7 ... ME, Sadler BM, Brine D et al (1983) Metabolism, disposition, and kinetics of delta-9-tetrahydrocannabinol in men and women Clin Pharmacol Ther 34:352–363 2) Agurell S, Halldin M, Lindgren J-E et...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 21)
... Main metabolic pathways of morphine, heroin and codeine The thick and thin arrows show the main and minor metabolic pathways, respectively ⊡ Figure 3.1 196 Morphine and its analogues GC and ... morphine Trends Neurosci 23:436–442 205 206 Morphine and its analogues 8) Matsubara K, Fukushima S, Akane A et al (1992) Increased urinary morphine, codeine and tetrahydropapaveroline in Parkinsonian ... Poppy seed ingestion and opiates urinalysis: a closer look J Anal Toxicol 14:308–310 10) Hasegawa M, Maseda C, Kagawa M et al (1992) Morphine and codeine being contained in poppy seeds and poppy...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 70)
... In > Table 5.1, clinical symptoms according to the concentrations of methemoglobin are presented ⊡ Table 5.1 Clinical symptoms appearing according to methemoglobin concentrations Methemoglobin ... Cyanosis in infants caused by nitrates in well water JAMA 257:2788–2792 12) Fan AM, Steinberg VE (1996) Health implications of nitrate and nitrite in drinking water: an update on methemoglobinemia ... containing nitrate salt can be considered However, a form or a product containing nitrate ingested could not be specified in the present poisoning case Notes a) When nitrite is present in blood,...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 71 and End)
... determination of methemoglobin in blood containing carboxyhemoglobin Forensic Sci Int 17:177–184 7) Sato K (1983) A method for determination of methemoglobin in blood containing carboxyhemoglobin ... Microdetermination of oxyhemoglobin, methemoglobin and sulfhemoglobin in a single sample of blood J Biol Chem 126:655–662 2) Leahy T, Smith R (1960) Notes on methemoglobin determination Clin Chem ... is read using cuvette A as reference, and this reading is A1 After allowing cuvette D to stand for 10 min, the absorbance at 630 nm is read using cuvette C as reference, and this reading is A3...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 22)
... suggesting a relatively short period between the times of his ingestion and death In addition, the ratios of cocaine to BE in blood and in the brain, and the brain-to-blood ratios of cocaine and ... 10.6 on average for urine sampled 0–8 h after the inhalation The ratios increased according to the increase in time interval between the inhalation and samplings [13–15] In the present case, the ... EL et al (1977) Cocaine and benzoylecgonine excretion in humans J Forensic Sci 22:697–707 15) Amber J (1985) The urinary excretion of cocaine and metabolites in humans: a kinetic analysis of published...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 23)
... two autopsy cases of pentazocine poisoning, its concentrations were 9.2 and 3.3 µg/mL in blood, 43 and 34 µg/g in the liver, and not detectable and 4.5 µg/mL in urine, respectively [12] The blood ... retention times of 3–7 and 7–8 min, respectively The amount of pentazocine and IS spiked into mL of blank whole blood or urine was equally 50 ng ⊡ Figure 5.2 222 Pentazocine Pentazocine In two autopsy ... pentazocine in blood The recovery of pentazocine using the Sep-Pak C18 cartridge was close to 100 % for both whole blood and urine [8] In this method, dextromethorphan is used as IS; the drug is being...
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