discuss the role of a security manager in an organization

... Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase Konstantinos Mavromatis 1, *, Iason Tsigos 2, *, Maria Tzanodaskalaki 2 , Michael Kokkinidis 1,3 and Vassilis ... the aromatic ring of Tyr269, and these unfavorable interactions could lead to a decrease of local flexibility and an increased E a value. The validity of the above interpretation was further reinforced ... exhibits an E a almost the same as in the case ofthenativeenzyme(Table1). Thermal inactivation of mutant and wild-type enzymes In order to investigate the effects of mutations on the stability of psychrophilic...

Ngày tải lên: 22/02/2014, 04:20

Ngày tải lên: 25/10/2013, 05:20

... state may be maintained mainly by key amino acids. In this study, two point-mutated proteins each with a single base substitution [alanine for tryptophan (W14 0A) and alanine for lysine (K13 3A) ] and ... the mutants without tryptophan at 140 (W14 0A and W140O) was much lower than both the wild-type protein and mutants E142O and K13 3A. Thermal analysis of protein unfolding The DSC curves of the wild-type ... investigated. Two point-mutated proteins, with a single base substitution of alanine for tryptophan (W14 0A) and alanine for lysine (K13 3A) , and two truncated fragment proteins, with fragments...

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Ngày tải lên: 21/03/2014, 22:01

... rupture of a pair of hydrogen bonds in the A and B b-strands near the amino terminus of the protein domain causes an initial extension of the protein, before the unfolding transition state is reached. [53] The ... be- tween the first amino acid of strand A (Y9) and the last amino acid of strand G (K87) . The elongation of the x(Y9)Àx(87) distance up to the transi- tion state is defined as the distance Dx A ÀG . ... b-strands. In Figure 5 B, we define the pulling coor- dinate for the A and G b-strands as the distance between the first amino acid of strand A (Y9) and the last amino acid of strand G (K87)....

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Ngày tải lên: 10/08/2014, 10:20

Ngày tải lên: 10/08/2014, 10:20

Ngày tải lên: 13/08/2014, 23:20

... average, command a significantly higher salary ($42,000 annually vs. $28,000 in average annual salary) Preserving Value Continuing education is important to preserving the market value of specialized ... knowledge and forming intellectual capital Nearly two-thirds of National Association of State Universities and Land-Grant Colleges (NASULGC) have research parks or business incubators (PASSHE has ... Programs and Initiatives Business accelerators and/or entrepreneurial initiatives Linking teaching and research to business opportunities Collaboration with local business and industry Small Business...

Ngày tải lên: 21/02/2014, 01:20

... (5Â-GGCAACAACCTACACTGGTATCA ACAAAAAYMGSRCRAATCTCCTCRGCTCCTGRTCW AKTATGCTTCCCAGTCCATCTCT-3Â) and g7EcoFor (5Â-AGTGAATTCTCATCTTTGACCCCCAGCGATTAT ACCAA-3Â). As a linker to connect these two, a DNA encoding ... To insert tHP downstream of the ORFs, tHP4 and tHP7 (5Â-AATTGGTACCCGATAAAAGCGGCTTCCTG AC-3Â), as well as tHP2 and tHP8 (5Â-AATTGAGG TGGGCTGCAAAACAAAACGGCCT-3Â), were annealed and ligated to the ... types of mutants were also observed. SPR analysis of antigen-binding affinity For the quantitative evaluation of the H39 mutation, kinetic analysis for antigen–Fv interaction of the wild-type and...

Ngày tải lên: 07/03/2014, 12:20

... semantic The Role of Lexico-Semantic Feedback in Open-Domain Textual Question-Answering Sanda Harabagiu, Dan Moldovan Marius Pasáca, Rada Mihalcea, Mihai Surdeanu, R azvan Bunescu, Roxana G rju, ... if (a) a vol- cano IS -A mountain; (b) lava IS-PART of vol- cano, and moreover it is a part coming from the inside; and (c) fragments of lava have all the prop- erties of lava, the following question ... WordNet: A Lexical Database. Commu- nication of the ACM, vol 38: No11, pages 39–41, Novem- ber 1995. Dan Moldovan, Sanda Harabagiu, Marius Pasáca, Rada Mihalcea, Richard Goodrum, Roxana Grju and Vasile Rus....

Ngày tải lên: 08/03/2014, 05:20

... revealed that the G-10L mutant protein is routed to the SecYEG translocon via the SRP pathway, the targeting pathway that is exploited by integral inner-membrane proteins. Together, these data indicate that ... Bioscience (Maarsen, the Netherlands). Bacterial strains The E. coli K-12strainsusedinthisstudyarelistedin Table 1. Strains CE1514 and CE1515 were obtained by P1 transduction using strain CE1224 as the ... understandable, as the SecB-binding sites, which are located in the mature domain of the PhoE precursor [3], are not affected in the G-10L mutant precursor. Thus, in the absence of SRP, SecB can target the...

Ngày tải lên: 08/03/2014, 09:20

... instrumental in maintaining social ties and serves as a mean of symbolic communication in social relationship. Most of the researches before and after the appearance of Sherry’s model in 1983 can ... brand attitude. It is the primitive assumption of balance theory that unbalanced triads tend toward balance. Although balance theory help to explain the change in recipient’s post brand attitudes ... have positive brand attitudes, then the triad is said to be unbalance. In this example, balance could be attained if the receiver changes to dislike the giver or having post favorable brand...

Ngày tải lên: 14/03/2014, 14:20

... suppres- sion. After in ltration, the treated plants were placed in the light, and the HR extent was evaluated by the ion leakage ratio at 12 and 48 h after in ltration. Mean values ± standard error of three replicates ... Key Laboratory of Monitoring and Management of Crop Diseases and Pest Insects, Ministry of Agricuture of R. P. China, Department of Plant Pathology, College of Plant Protection, Nanjing Agricultural ... with ABA or H 2 O, ParA1 and the spin trapping assay reagent were coinfiltrat- ed into the leaves, and the plants were placed under light. After 6 h, the levels of OH ã in the leaf tissues obtained from...

Ngày tải lên: 15/03/2014, 00:20

... savings may increase the means to afford college. The other effect is indirect and mainly attitudinal. Having savings over a period of years may raise a young person’s educational expectations ... to increase youth account ownership and savings may play an important role in helping to restore the American Dream of attending college. Because this research finding has simple, doable, and ... importance of youth savings for understanding college attendance. Conclusion Findings from this study suggest that factors other than desire and ability play an important role in determining...

Ngày tải lên: 15/03/2014, 10:20

... and the nuclear ⁄ cytoplasmic ratio was analysed from the Gray images using Lucia G ⁄ F Analysis Software [6]. Data analysis Results are presented as mean ± SE for the number of hepatocyte preparations ... were washed in NaCl ⁄ P i , fixed in 4% (w ⁄ v) paraformaldehyde in NaCl ⁄ P i and stained for glu- cokinase with a rabbit IgG against human glucokinase:318– 405 (H88, sc-7908; Santa Cruz) and fluorescein ... h and 3 h incubations, and the cell content of Glc6P and the activ- ity of phosphorylase were also similar after 1 h and 3 h. Metabolite and enzyme assays Glc6P and Fru2,6P 2 were determined as...

Ngày tải lên: 16/03/2014, 14:20