directed energy funneling in proteins from structure to function

... Fasciculin Plasminogen small small small 1reiA Phosphatidylinositol 3-kinase a-Spectrin, SH3 domain Signal transduction protein Seed storage protein s vicillin Immunoglobulin Diphtheria toxin NADH ... Oncomodulin a 1ivpA Adenovirus fibre STNV coat protein Pseudoazurin Transthyretin Picornavirus Cellular retinoicacid-binding protein (HIV-2) protease b 1lbbA 2sas Calcium-binding protein Parvalbumin ... transduction protein Ferredoxin II, Peptostreptococcus Ferredoxin II, Desulfovibrio gigas Ribonuclease A c-src Tyrosine kinase Prion protein domain MHC class II p41 invariantchain fragment Methylamine dehydrogenase...

Ngày tải lên: 07/03/2014, 16:20

... relative to rice from 1989 to 2006 The relative price of pork versus rice increased from about in 1989 to in 1997, and then decreased to 4.5 in 2006 This finding suggests the protein/fat rich foods ... finding in Smith et al (2005) based on data from 36 developing countries This study may be subject to some limitations First, due to data limitations, we mainly use anthropometric indicators to ... percentage points can be explained by the observed factors, and the remaining are attributed to the unobserved factors There are similar findings for the outcome of being underweight (Insert Table...

Ngày tải lên: 18/02/2014, 15:20

... them indiscriminately The main routine construct tree in Fig separates the list of input chunks and passes each one to the subroutine process chunk in Fig where the chunk is then turned into one ... such as the input shown in Fig 1, the chunker produces a structure in which some constituents remain unattached or partially annotated in keeping with the chunk-parsing strategy to factor out recursion ... a complete match of the input with a stored instance exists In all other cases, the most similar tree from the instance base needs to be modified to match the chunked input This means that the...

Ngày tải lên: 17/03/2014, 07:20

... is a domain in spectacular expansion, incorporating continuously the progress in fundamental and applicative physics, from relativity to materials science, and responding, in this way, to the challenges ... R sin φ − y0 )2 = cos θ = y0 − R sin φ r hence E= R2 + y2 − 2Ry0 sin φ ; (13) σR π/2 y0 − R sin φ dφ π −π/2 R2 + y2 − 2y0 R sin φ (14) When entering the integral into the Mathematica online integrator ... consistent in the case of linear currents and charge distributions This chapter brings together the results from a dozen or so treatments of the topic in an internally consistent manner Certain points...

Ngày tải lên: 28/06/2014, 15:20

... Yamanaka Y, Saitou Y, Sugimoto K, Nakano T: Targeting of X-linked inhibitor of apoptosis protein or Survivin by short interfering RNAs sensitises hepatoma cells to TNF-related apoptosis-inducing ligand- ... cellular colony growth in human cancer cells, which was found to be due to the induction of apoptosis [48] 3.1.3 Inhibitor of apoptosis proteins (IAPs) The inhibitor of apoptosis proteins are a group ... [27] Other apoptotic factors that are released from the mitochondrial intermembrane space into the cytoplasm include apoptosis inducing factor (AIF), second mitochondria-derived activator of caspase...

Ngày tải lên: 10/08/2014, 10:21

... described in Bangladesh [20] These studies indicate that travel to the Indian subcontinent, in patients returning to Western Canada with traveler’s diarrhea should be determined to guide initial ... dominance of S flexneri STs and in isolates of Indian origin and cases of traveler’s diarrhea associated with the Indian subcontinent [23] One factor driving multi-drug resistance in the Indian ... resistance in Shigella species originating from the Indian subcontinent [21] It is possible that part of this emerging resistance may be associated with the increasing dominance of specific STs or clones...

Ngày tải lên: 11/08/2014, 14:21

... less than months: ≥ 60/minute age 2–11 months: ≥ 50/minute age 1–5 years: ≥ 40/minute ALRI Above symptoms with: Chest indrawing Stridor Nasal flaring Grunting Symptoms of severe pneumonia ... shown in Table Temporal distribution of respiratory viruses The number of RSV infections increased during late fall and peaked between October and January during the first year of the study During ... detected during the first year of the study, influenza A in winter months and hMPV in spring season (Figure 3) Table 3: Virus identifications in children with ALRI detected positive for viral infections...

Ngày tải lên: 12/08/2014, 04:22

... changes in the low SES group from 2001 to 2008, adding support to our findings in the present study The contradicting results on the time trend in FV intake found in the current study, compared to ... shows an increase in SES disparity in FV intake among 10-12 year olds from 2001 to 2008, wherein low SES children had a steeper decline in FV intake than high SES children This increase in SES ... regarding changes in FV intake within the same age group from 2001 to 2008, wherein high SES children had a higher increase in accessibility and preferences than low SES children This increasing...

Ngày tải lên: 14/08/2014, 08:21

Ngày tải lên: 26/03/2015, 10:43

... historical context into account in understanding these verses Some progressive Muslim feminists in Indonesia that I will examine in this work have been developing arguments to justify a reinterpretation ... feminism in Indonesia as situated in a context of intellectual continuity with Islamic traditions from the past Islamic feminism in Indonesia does not exist in an historical vacuum Muslim feminists ... to gain my gratitude The “financial instability” in their life inspired me to work hard in completing my study Dr Elizabeth Fuller Collins who gave me unlimited guidance, not only in finishing...

Ngày tải lên: 14/05/2015, 12:10

... Advertising spending in Vietnam from 2008 to 2015 Advertising spending in Vietnam from 2008 to 2015 (in million U.S dollars) 120 99 100 912 835 71 00 717 61 62 Sp en ding in millio n U.S ... regarding this statistic can be found on page Source: IMF; Media Partners Asia; ID 257578 120 Advertising spending in Vietnam from 2008 to 2015 Advertising spending in Vietnam from 2008 to 2015 (in ... Further information regarding this statistic can be found on page Source: IMF; Media Partners Asia; ID 257578 Advertising spending in Vietnam from 2008 to 2015 Advertising spending in Vietnam from...

Ngày tải lên: 28/06/2015, 04:39

... have to find others, not inconsistent with WTO rules This policy includes the hard infrastructure building, training of local personnel, technological innovation, attracting of FDI and multinationals, ... industry: its share rose from 12 to 20% of GDP and from 70 to 85% in the industry itself The contribution of this advanced sector to export increased from 52 to 68% in 1995-2007(8) Industrial growth ... the world on a number of indicators, including indicators of information development Much of Vietnam low indexes were due to the following factors: • Backwardness of infrastructure necessary for...

Ngày tải lên: 03/09/2016, 12:56

... Converting Binary Numbers into Decimal 16 Converting Decimal Numbers into Binary 16 Converting Binary Numbers into Hexadecimal 18 Converting Hexadecimal Numbers into Binary ... Remainder (LSD) Remainder Remainder Remainder Remainder Remainder Remainder (MSD) The binary number is 11110102 1.8 Converting Binary Numbers into Hexadecimal To convert a binary number into hexadecimal, ... 1.22 Converting a Floating Point Number into Decimal To convert a given floating point number into decimal, we have to find the mantissa and the exponent of the number and then convert into decimal...

Ngày tải lên: 15/12/2016, 16:37

... deletion of RasGEF; KIND1, KIND1 domain; KIND2, KIND2 domain (B) KIND2 domain anchors v-KIND to dendrites Flag-tagged v-KIND, DKIND1, DKIND2, DKIND1 + 2, DRasN, DGEF, KIND1 or KIND2 together with EGFP ... controlling dendrite growth and branching Results The KIND2 domain of v-KIND has a unique ability to localize to dendrites via MAP2 binding, which is absent in the KINDs from other KIND-containing proteins ... [8] and Ras guanine exchange factor (RasGEF) veryKIND (v-KIND, or kinase noncatalytic C-lobe domain containing 1) [9] The KIND domain in these proteins is localized to the N-terminal region, and...

Ngày tải lên: 14/02/2014, 19:20

... primarily aiming at demonstrating structure- modifying and not symptom-modifying effects might explain why no symptomatic effects from ASUs were detected in the long-term study Indeed, symptoms and ... DS, Lindmark L: An in vitro screening assay for inhibitors of proinflammatory mediators in herbal extracts using human synoviocyte cultures In Vitro Cell Dev Biol Anim 2004, 40:95-101 118 Innes ... hydrolysate, gelatin, gelatin + glycin + CaHPO4*2H2O, or egg albumin [138] The gelatin preparations were not significantly different from each other and were superior to egg albumin in reducing pain as assessed...

Ngày tải lên: 09/08/2014, 08:22

... obtained from partially cooked white rice samples Lettering refers to the cooking time in minutes Figure DTG records from partially cooked white rice (lettering refers to the cooking time in minutes ... °C Figure TGA traces obtained from partially cooked white rice samples Lettering refers to the cooking time in minutes A more interesting information comes from the inspection of the DTG traces ... Gelatinization White rice: Starch gelatinization in white rice is sustained by the water intake and progresses from the kernel surface toward the core The water intake produces the swelling of...

Ngày tải lên: 19/03/2015, 13:36

... underlined) Autodocking Automated docking simulations were performed using AutoDock4 [39–41] using the crystal structure of BC1534 (2ixd.pdb) to generate atomic energy grids Point mutations were introduced ... assigned to the protein and carbohydrate atoms Atomic interaction energy grids were determined using probes corresponding to each atomic type ˚ found in the ligand at 0.375 A grid positions in a ... reflecting different functions All proteins for which the enzymatic function has been studied belong to different groups The two Bacillus proteins were placed in functional categories different from...

Ngày tải lên: 15/03/2014, 11:20

... the interatomic spacing The interatomic spacing can determined through laser interferometry The method is currently limited to a precision of about 10−5 because of uncertainties in the isotopic ... nucleon is worth remembering! The additivity of binding energies is quite different from what happens in atomic physics where the binding energy of an atom with Z electrons increases as Z 7/3 , i.e ... beryllium target at GSI laboratory are momentum selected [12] and then injected into a storage ring [13] About 10 fully ionized ions are injected into the ring where they are stored for several hundred...

Ngày tải lên: 17/03/2014, 14:37

... http://www.virologyj.com/content/7/1/376 binding domain and a C-terminal effector domain [19] The effector domain interacts with proteins involved in the 3’-end cellular mRNA processing, inhibits mRNA export and pre-mRNA splicing ... signalling of antiviral proteins, such as RIG-I, PKR, OAS/RNase L, activators of mitogenactivated protein kinase and transcription factors involved in type I IFN and inflammatory cytokine signalling ... decrease in A549 cells Expression of NS1 proteins in A549 cells To find out whether the difference in inhibition of IFNb promoter is duo to difference in- or insufficient expression of the NS1 proteins...

Ngày tải lên: 11/08/2014, 21:21