difference between acute and chronic lymphoblastic leukemia
Chapter 104. Acute and Chronic Myeloid Leukemia (Part 1) ppsx
... the past by the Food and Drug Administration (FDA) for marketing based on trials using the FAB criteria. Acute Myeloid Leukemia Incidence The incidence of acute myeloid leukemia (AML) is ... years after exposure, and affected individuals have aberrations in chromosomes 5 and 7. Topoisomerase II inhibitor–associated leukemias occur 1–3 years after exposure, and affected individuals ... recent literature and some ongoing studies use the FAB classification, a description of this system is also provided in Table 104-1. A major difference between the WHO and FAB systems is the...
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Chapter 104. Acute and Chronic Myeloid Leukemia (Part 2) pot
... Acute myelomonocytic leukemia Acute monoblastic and monocytic leukemia Acute erythroid leukemia Acute megakaryoblastic leukemia Acute basophilic leukemia Acute panmyelosis ... Minimally differentiated leukemia 5% M1: Myeloblastic leukemia without maturation 20% M2: Myeloblastic leukemia with maturation 30% M3: Hypergranular promyelocytic leukemia 10% AML with 11q23 ... Myelomonocytic leukemia 20% M4Eo: Variant: Increase in abnormal marrow eosinophils M5: Monocytic leukemia 10% M6: Erythroleukemia (DiGuglielmo's disease) 4% M7: Megakaryoblastic leukemia...
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Chapter 104. Acute and Chronic Myeloid Leukemia (Part 3) pps
... Continuous activation of Flt3 and downstream target kinases, including signal transducer and Chapter 104. Acute and Chronic Myeloid Leukemia (Part 3) Immunophenotype and Relevance to the WHO ... for separating AML from acute lymphoblastic leukemia (ALL) and identifying some types of AML. For example, AML that is minimally differentiated (immature morphology and no lineage-specific ... Similarly, acute megakaryoblastic leukemia can often be diagnosed only by expression of the platelet-specific antigens CD41 and/ or CD61. While flow cytometry is useful, widely used, and, in some...
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Chapter 104. Acute and Chronic Myeloid Leukemia (Part 4) pps
... by impaired phagocytosis and migration and morphologically by abnormal lobulation and deficient granulation. Figure 104-1 Chapter 104. Acute and Chronic Myeloid Leukemia (Part 4) Clinical ... anemia. The median presenting leukocyte count is about 15,000/àL. Between 25 and 40% of patients have counts <5000/àL, and 20% have counts >100,000/àL. Fewer than 5% have no detectable leukemic ... blood. The morphology of the malignant cell varies in difference subsets. In AML the cytoplasm often contains primary (nonspecific) granules, and the nucleus shows fine, lacy chromatin with one...
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Chapter 104. Acute and Chronic Myeloid Leukemia (Part 5) docx
... Chapter 104. Acute and Chronic Myeloid Leukemia (Part 5) Morphology of AML cells. A. Uniform population of primitive myeloblasts with immature chromatin, nucleoli in some cells, and primary ... Ecchymosis and oozing from IV sites (DIC, possible acute promyelocytic leukemia) Fever and tachycardia (signs of infection) Papilledema, retinal infiltrates, cranial nerve abnormalities (CNS leukemia) ... patients, and about 25% have counts <25,000/àL. Both morphologic and functional platelet abnormalities can be observed, including large and bizarre shapes with abnormal granulation and inability...
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Chapter 104. Acute and Chronic Myeloid Leukemia (Part 6) pps
... achievement of CR. In addition, patients who achieve Chapter 104. Acute and Chronic Myeloid Leukemia (Part 6) Most patients are anemic and thrombocytopenic at presentation. Replacement of the appropriate ... entering CR, the length of CR, and the curability of AML. CR is defined after examination of both blood and bone marrow. The blood neutrophil count must be 1000/àL and the platelet count 100,000/àL. ... nervous system bleeding and pulmonary leukostasis contribute to poor outcome with initial therapy. In addition to pretreatment variables such as age, cytogenetics, and leukocyte count, several...
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Chapter 104. Acute and Chronic Myeloid Leukemia (Part 7) pot
... 104. Acute and Chronic Myeloid Leukemia (Part 7) Acute Myeloid Leukemia: Treatment Treatment of the newly diagnosed patient with AML is usually divided into two phases, induction and postremission ... diagnosed acute myeloid leukemia. For all forms of AML except acute promyelocytic leukemia (APL), standard therapy includes a 7-day continuous infusion of cytarabine (100–200 mg/m2 per day) and ... synthesis and thereby overcome resistance to standard-dose cytarabine. In two randomized studies, high-dose cytarabine with an anthracycline produced CR rates similar to those achieved with standard...
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Tài liệu Canadian clinical practice guidelines for acute and chronic rhinosinusitis pdf
... Comparison of the efficacy and tolerability of amoxycillin/clavulanic acid 875 mg b.i.d. with cefuroxime 500 mg b.i.d. in thetreatment of chronic and acute exacerbation of chronic sinusitis inadults. ... research tools and are not currently available in the clinical setting.Maxillary Sinus Aspirate (MSA) MSA is consideredthe gold standard for bacterial recovery in acute and chronic sinusitis, ... 3338 patients from 16randomized comparative non-placebo studies concludedthat differences between antimicrobial agents are smallin otherwise healthy adults and adolescents, and there-fore an...
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Tài liệu Acute and chronic sinusitis pdf
... Acute and chronic sinusitis PLAIN X‐RAYSFluid level frontal sinuses Surgical treatment chronic Surgical treatment chronic maxillary sinusitis yInferior ... Pharyngeal, laryngeal and ear infectionsã Mucoceleã OsteomyelitisObit l li tiãOrbital complicationsãIntracranial complicationsãIntracranial complications Acute sinusitis Acute sinusitis ... (sinusitis)Fluid Level (sinusitis) CT SCANComplete opacity Rt sphenoid siunus Treatment of chronic maxillary sinusitisCld llL ’ tiCaldwell Luc’s operation Orbital ComplicationsOrbital...
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