diagnosis of the reactions to the stress of combat
Báo cáo khoa học: Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress pdf
... periods of time (Fig 3) As shown, the addition of stressors to the cultures inhibits growth without killing the cells The hybridizing band in the northern analysis showed the expected size of about ... role in the detoxification processes In this study we examined the role of Bcp2 in order to increase the knowledge of the enzymatic activity involved in the oxidative stress in S solfataricus To detect ... examined the involvement of the peroxiredoxin Bcp2 in oxidative stress in the hyperthermophilic aerobic archaeon Sulfolobus solfataricus Furthermore, we report the cloning, the expression and the...
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Báo cáo khoa học: Functional studies of crustacean hyperglycemic hormones (CHHs) of the blue crab, Callinectes sapidus – the expression and release of CHH in eyestalk and pericardial organ in response to environmental stress pot
... examined the physiological responses of the release and expression of these two CHHs under stressful conditions, especially severe hypoxia, hypothermia and hyperthermia, in an attempt to define their ... functions To address these questions, we cloned the fulllength cDNA of PO-CHH and identified the presence of the neuropeptide forms in the ES and PO For the first time in crustaceans, the expression ... revealing the presence of a long 3¢-UTR ( 1.5 kbp) The amplicon (132 bp) produced from the nested PCR of 5¢-RACE cDNA contained a 5¢-UTR and the remaining sequence of the 5¢-end of PO-CHH The complete...
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THE DIMENSIONS OF AESTHETIC REACTIONS TO MUSIC doc
... Like (2), these refer to the intrinsic qualities of the music itself, but they differ in that they describe qualities of the music as a whole 16 rather than specific, technical elements of it (e.g ... first describe the development of the system of content analysis, and then deal with its applicatio:1 to the experimental data Development of the Content Analysis Musicians and aestheticians have ... unlikely to produce a large number of the other three types, especially Objective-Analytic ones; these subjects, moreover, are likely to be amongst the less musically experienced The results of the...
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A Perception-Based View of the Employee: A Study of Employees’ Reactions to Change doc
... due to two key reasons: theoretical aspect (the greater the number of variables in the model, the less the degree of parsimony of the model), and practical aspect (the greater the number of variables ... assumed that the strength of the impact of the change was inherently expressed in the perceptions of the employees, it was not necessary to separately explore the effects of the change on the employees, ... rate) The focus of this dissertation is strictly limited to the examination of the relationships between perceptions and attitudes on the one hand and reactions to change on the other hand at the...
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Báo cáo khoa học: Proteolysis of the tumour suppressor hDlg in response to osmotic stress is mediated by caspases and independent of phosphorylation pot
... cells prolonged exposure to hypertonicity induces apoptosis because of a lack of or the dysfunction of the component(s) needed for the adaptive response of these cells to stress For example, it ... loss of E-cadherin or other protein(s) in the hDlg complex under stressful conditions, and the cortical cytoskeleton is therefore disrupted and hDlg released into the cytoplasm The lack of effect ... from the cytoskeleton into the cytoplasm [3] Our aim in this study was to gain a better understanding of the role of hDlg phosphorylation by p38c when cells are exposed to hyperosmotic stress...
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Báo cáo khoa học: The calcium-binding domain of the stress protein SEP53 is required for survival in response to deoxycholic acid-mediated injury pdf
... published in the PhD thesis of J Darragh, University of Dundee) The effect of proton pump inhibitor (PPI) medication on bile acid levels was also investigated The total bile acid concentrations of patients ... (Fig 3I) The control inactive version of the inhibitor bisindolylmaleimide V (Bis-V) was unable to block the apoptosis (Fig 3J), demonstrating the selectivity in the response Because the PKC pathway ... rather than p53, is a primary mediator of the differential apoptotic response of the two cell lines Gastric fluid contains a mixture of different bile acids in addition to DCA (as in Fig 2B) These...
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Báo cáo hóa học: " Validity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic component" docx
... 100% 0% > 10 Cutoff point A score > points in the sum of the 10 items of the DN4 questionnaire resulted in the best discriminant cut-off point for the overall sample Cut-off point in the DN4 questionnaire ... diagnosis, and the area under the curve (AUC) calculated by the trapezoid method and its significance level were estimated The 95% confidence intervals (95% CI) of the estimators of the cut-off ... related to reliability of the Spanish version of the DN4 questionnaire Our data support the reliability of the instrument both in terms of internal consistency (Cronbach's α of Page of 10 (page...
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báo cáo hóa học:" Validity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic component" pdf
... 100% 0% > 10 Cutoff point A score > points in the sum of the 10 items of the DN4 questionnaire resulted in the best discriminant cut-off point for the overall sample Cut-off point in the DN4 questionnaire ... diagnosis, and the area under the curve (AUC) calculated by the trapezoid method and its significance level were estimated The 95% confidence intervals (95% CI) of the estimators of the cut-off ... related to reliability of the Spanish version of the DN4 questionnaire Our data support the reliability of the instrument both in terms of internal consistency (Cronbach's α of Page of 10 (page...
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Báo cáo khoa học: "Metabolism of isopentenyladenosine in the roots of Norway spruce seedlings exposed to nutritive stress" pdf
... seedlings The morphology of stressed seedlings grown on the BLF medium differs from that of the Ingestad seedlings (control) The stressed seedlings exhibited a lower rate of shoot growth, tended to ... roots These seedlings produced a great number of lateral roots Further characteristics of the BLF seedlings were a reduced length of the primary root and an increased ratio of the root to shoot ... added to the BLF medium in form of AlCl (0.8 mM) The compo3 sition of the nutrient media Ingestad (control) and BLF (stress) was taken from Junga (1984) The nutrient media were changed weekly The...
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Báo cáo y học: "α Anti-α-fodrin antibodies do not add much to the diagnosis of Sjögren’s syndrome" pot
... antibodies [12] The objective of this study was to measure the presence of anti-α-fodrin antibodies in the sera of a cohort of patients with well-defined SjS at the Department of Rheumatology of the University ... In our hands, the use of apoptotic extracts (to increase the amount of antigenic fodrin cleavage product) did not improve the suitability of these techniques for the detection of anti-α-fodrin ... false-positive results because of the presence of the GST moiety in the α-fodrin–GST product that was used as the antigen, the ELISA was also performed in the presence of a 10-fold excess of purified carrier...
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Báo cáo y học: "Effect of dsDNA binding to SmD-derived peptides on clinical accuracy in the diagnosis of systemic lupus erythematosus" potx
... by the area under the curve of the receiver-operating characteristic analysis (see Figure 1) After adjusting the cutoff value of the SmD1 immunoassay to 100 IU/ml to achieve 100% specificity, the ... in the ELISA according to the instructions for use of the respective kit Statistical evaluation of results The results obtained from the comparative study were evaluated using the Analyse-it Software ... decision about the diagnosis of the patient and commence inappropriate therapy In a second independent cohort of patients (panel III), the newly defined cut-off limit (100 units) of the SmD1 ELISA...
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báo cáo khoa học: "Hypersensitivity reactions to anticancer agents: Data mining of the public version of the FDA adverse event reporting system, AERS" ppsx
... this study were taken from the public release of the FDA’s AERS database, which covers the period from the first quarter of 2004 through the end of 2009 The data structure of AERS is in compliance ... investigated and the number of cooccurrences of HSRs would be important factors In this study, we tried to evaluate the demographic effect on the susceptibility to severe HSRs The ratio of male/female/unknown ... using the IC is done using the IC025 metric, a criterion indicating the lower bound of the 95% two-sided CI of the IC, and a signal is detected with the IC025 value exceeds [10] Finally, the EB05...
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báo cáo khoa học: "A trial platform to develop a tailored theory-based intervention to improve professional practice in the disclosure of a diagnosis of dementia: Study protocol [ISRCTN15871014]" potx
... development of the intervention The Faculty of Old Age Psychiatrists of the Royal College of Psychiatrists has agreed to appoint a member to liaise with us in regard to the design and conduct of the ... distribution to members of local old age MHTs; when members of old age MHTs receive the letters, they can decide whether to opt in to the survey and return their names and preferred contact details to ... sample the 60 MHTs in the North of England and Yorkshire, and another 60 randomly selected from the rest of the UK The former will be subsequently approached for recruitment to the RCT; the latter...
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Báo cáo y học: "A rare case of intussusception leading to the diagnosis of acquired immune deficiency syndrome: a case report" pps
... bowel can lead to intussusception [10,11] Nonetheless, the diagnosis is particularly difficult in this population of patients due to the non-specific nature of the symptoms as well as the depressed ... abdominal tomography at the level of the umbilicus showing a characteristic 'target mass' (arrows) in the right abdomen Contrast Contrast enhanced abdominal tomography at the level of the umbilicus ... (arrows) in the right abdomen Discussion Bowel obstruction is one of the most common complaints driving patients to our emergency department In the vast majority of cases, a history of previous...
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Báo cáo y học: "The organisation of the stress response, and its relevance to chiropractors: a commentary" pdf
... through the bed-nucleus of the stria terminalis to the hypothalamus [8], which projects to the lateral hypothalamus to mediate the activation of sympathetic component of the ANS [36]; projections to ... the ANS [36]; projections to the dorsal motor nucleus of the vagus are involved in the activation of the parasympathetic component of the ANS [37]; projections to the NLC and ventral tegmental ... inflammatory stress, interleukin-6 (IL-6) plays a major role of the endocrine cytokines in the immune stimulation of the HPA axis [73] Chronic activation of the stress response has been found to impair...
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The roles of shca proteins in response to oxidative stress 1
... nuclei 30 10 30 cytosol Figure 3.4E Phosphorylation of FOXO3a at Thr32 induced by H O involved ERKs activation H O treatment led to translocation of FOXO3a from the nucleus to the cytoplasm Cells ... H2O2 for different periods of time, harvested, and separated to the nuclear and cytoplasmic fractions The levels of FOXO3a, TopBP1 (nucleus control), and p66shcA (cytoplasm control) were determined ... Phosphorylation of p66shcA on Ser36 was determined by Western blot analysis (D) Coexpression of the constitutively active MEK1 (MEK1 ) led to massive phosphorylation of p66shcA on Ser36 The mutant form of...
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The roles of shca proteins in response to oxidative stress 2
... expressed both p52 and p46 Shc due to the use of two start codons Bottom panel: quantitation data from B The value of co-immunoprecipitated p52Shc or p46Shc in the absence of H2O2was set at -95- C IP: ... analysis of phosphorylation sites on ShcA Tandem mass spectrum showing the sequence of a peptide of m/z 611.7891 which was eluted from the reversed phase column at 37.15 The y-ion series shows the ... p46ShcA with PKC δ The experiment was done as Fig 2A, except that this p52ShcA construct did not express p46 due to a point mutation Bottom panel: quantitation data from C The value of co-immunoprecipitated...
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Báo cáo y học: " the Value of Serum Biomarkers (Bc1, Bc2, Bc3) in the Diagnosis of Early Breast Cancer"
... since none of them alone is useful for the majority of the BC and none of them is specific for cancer or breast tissues No biomarker has been suggested to date for the early diagnosis of BC (24) ... method to evaluate the actual performance of these markers Jinang Li, from the John Hopkins Hospital, is the first to explore proteomics in early diagnosis of BC, who also enabled the advance of ... response rather than malignancy Another study by Mathelin et al included a total of 89 patients Bc1a and Bc1b defined by the authors corresponded to the Bc1 and Bc3a and Bc3b corresponded to Bc3 of Li...
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Tài liệu Role of diffusion-weighted imaging in the diagnosis of gynecological diseases pdf
... (SENSE factor of 2) Imaging time of DWI was 90 s for 20 slices Detection of uterine malignancy The ADC values of uterine cancers are lower than of normal tissue On the other hand, in sarcomas the ADC ... in the diagnosis of intracranial epidermoid cyst [50] Detecting the keratinoid substance by means of DWI and the ADC value may be useful and serve as an adjunctive tool to ensure the accuracy of ... pulse, the low ADC values of the cystic component of mature cystic teratomas have been attributed to artifacts caused by coexisting fat within the tumor [21, 22] Furthermore, mature cystic teratoma...
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A COMPARATIVE STUDY OF THE DIAGNOSIS OF PULMONARY TUBERCULOSIS USING CONVENTIONAL TOOLS AND POLYMERASE CHAIN REACTION* pot
... effort for developing new tools to diagnose tuberculosis1 The use of a molecular technique like PCR for the laboratory detection of Mycobacteria in respiratory and other tissue samples from tuberculosis ... of six months after being diagnosed as not having tuberculosis, the PCR profile of the individual had changed markedly, suggesting an increase in the bacterial load in the sputum Only seven of ... clinical follow up Of the 144 samples, 48 were confirmed on the basis of culture and response to ATT, while 23 culture negative samples were confirmed on the basis of response to ATT, microbiological...
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