dhea and cancer risk or prevention

... Early Cancer and Cancer Risk Infrastructures were built to improve informatics and information flow across the Network A public web site and a secure web site contained general and specific information ... on Biomarkers of Early Cancer and Cancer Risk Biomarker Development Laboratories in 2008 These laboratories are responsible for development and characterization of new, or refinement of existing, ... colon cancer project; the Carotene and Retinol Efficacy Trial (CARET) for a lung cancer and mesothelioma project; and the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO) for...

Ngày tải lên: 14/02/2014, 21:20

... bioassays and are carcinogenic (Gold et al., 1997b) Dehydroepiandrosterone (DHEA) and DHEA sulfate are the major secretion products of adrenal glands in humans and are precursors of androgenic and ... divided by (Gaylor and Gold, 1998) Both linear extrapolation and the use of safety or uncertainty factors proportionately reduce 806 CHAPTER 38 Pesticide Residues in Food and Cancer Risk: A Critical ... cell killing and consequent cell replacement (a risk factor for cancer that can be limited to high doses) and that ignoring this effect in risk assessment can greatly exaggerate risks We estimate...

Ngày tải lên: 14/02/2014, 22:20

... Primary handler - Mixing/loading/applying wettable powders to fruit trees Residential Food Aggregate DWLOC cancer Cancer Cancer Food and ppb Risk Risk Residential 6.5x10 Secondary handler - Painting ... Acceptable daily intake for man: - 0.1 mg/kg Signs of Toxicity – Humans: Individuals working with captan or in fields where captan was applied reported eye and skin irritation Investigators conducted patch ... health effects Distribution and excretion Cancer risk Characterization Toxicity on animal Toxicity to human Cancer risk Notes Captan introduction 1,2,3,6-tetrahydro-N- (trichloromethylthio) phthalimide...

Ngày tải lên: 28/05/2016, 11:38

... 2007, in risk estimates according to the histological type of lung cancer [16] As for the C8092A polymorphism, no association was found between the polymorphism and lung cancer risk in Norwegians ... polymorphism and risk of primary lung cancer Carcinogenesis 2003; 24: 1677-81 57 Cui Y, Morgenstern H, Greenland S, et al Polymorphism of Xeroderma Pigmentosum group G and the risk of lung cancer ... damage and may influence an individual's risk of lung cancer, because the variant genotype in those polymorphisms might destroy or alter repair function 3-2 XPA G23A polymorphism and lung cancer risk...

Ngày tải lên: 31/10/2012, 14:59

... Reproductive and hormonal risk factors Epidemiol Rev 15:36-47, 1993 World Cancer Research Fund Food, Nutrition and the Prevention of Cancer: a global perspective Washington, DC: American Institute for Cancer ... and risk of (a) early breast cancer and (b) late breast cancer Table Summary of the results on the relationship between breast cancer and reproductive factors according to age at diagnosis Risk ... Breast cancer risk increased with increasing age at FFTP by 5% (95% CI: 5-6%) per year for breast cancer diagnosed early or before menopause and by 3% (95% CI: 2-4%) for cancers diagnosed late or...

Ngày tải lên: 05/03/2014, 17:20

... cancer odds ratios (matched analysis) and menopausal status with BMI and selected risk factors and major sectors, by conditional logistic regression Model/ Parameter OR (95% CI) OR (95% CI) OR ... canning (OR = 3.5; 95% CI, 1.2-10.1) after adjusting for reproductive history and SES [57] Band et al found elevated premenopausal breast cancer risk for work in food and beverage processing (OR = ... http://www.ehjournal.net/content/11/1/87 Page of 17 Table Major and minor sectors, and counts of controls and cases by minor sector of longest duration Major sector Non-plastics light manufacturing Cases 1006...

Ngày tải lên: 06/03/2014, 02:21

... year for which breast cancer incidence is available (2005 for Republic of Ireland; 2004 for England & Wales, Scotland, Northern Ireland, and Sweden; 2003 for Czech Republic and Finland; 2001 for ... abortion statistics are used to derive abortion rates for Northern Ireland The trends in abortion and fertility in Northern Ireland are shown in Figures and Abortion rates in Ireland, where abortion ... cohort breast cancer incidence for women aged 50–54 or 45–49 Explanatory variables: cumulated cohort abortion rates and cumulated cohort fertility rates Table Summary: Forecast Cases of Breast Cancer...

Ngày tải lên: 06/03/2014, 02:21

... Xu X Risk factors for oesophageal cancer in northeast China Int J Cancer 1994; 57: 38-46 Gao YT, McLaughlin JK, Gridley G, Blot WJ, Ji BT, Dai Q, Fraumeni JF Jr Risk factors for esophageal cancer ... Qiao YL, Taylor PR Prospective study of risk factors for esophageal and gastric cancers in the Linxian general population trial cohort in China Int J Cancer 2005; 113: 456-463 Correa P, Fontham ... insufficient for GC and possible for OC[8] A previous review of dietary nitrates, nitrites and NOC and risk of nasopharynx, oesophagus, stomach, pancreas, colorectal and brain cancer concluded...

Ngày tải lên: 06/03/2014, 02:21

... 3053 Email: graham.giles@cancervic.org.au Canada Professor Daniel Krewski NSERC Chair in Risk Science Professor and Director McLaughlin Centre for Population Health Risk Assessment University ... reports on mobile phone use and brain cancer risk ANNEX A: LIST OF MEMBERS AND CONTACT DETAILS IARC/CREAL Professor Elisabeth Cardis Research Professor in Radiation Epidemiology CREAL-Centre for ... study reports on mobile phone use and brain cancer risk Germany Dr Joachim Schüz Head, Department of Biostatistics and Epidemiology Institute of Cancer Epidemiology Danish Cancer Society Strandboulevarden...

Ngày tải lên: 06/03/2014, 02:21

... lubricants and water based paints • Recycle waste where possible – In England, Northern Ireland and Wales contact your local council or waste contractor for recycling facilities In Scotland in the ... nearby Provide appropriate temporary storage for any oils and chemicals Contain all spillages using absorbents such as sand, soil or commercially available booms or pads and notify us immediately, ... solvents (toluene or chlorinated hydrocarbons ) • provide safe and secure storage For guidance on general storage see our ‘Pollution Prevention Pays Getting your site right’ pack and DVD reference...

Ngày tải lên: 06/03/2014, 23:20

... exposure and breast cancer risk - which could support associations with either increased or decreased risk FACT SHEET #46 Cornell University Program on Breast Cancer and Environmental Risk Factors ... lung cancer For example, people who smoke the least (or for the shortest time) have the lowest risk of lung cancer, while people who smoke the most (or for the longest time) have the highest risk ... the Program on Breast Cancer and Environmental Risk Factors in New York State Printed on recycled paper with soy-based ink Program on Breast Cancer and Environmental Risk Factors (BCERF) College...

Ngày tải lên: 15/03/2014, 01:20

... Ministry of Health, Welfare and Sports (VWS); and ZONMw We thank Statistics Netherlands (CBS) and Netherlands Cancer Registry (NKR) for data on cancer and death, and screening organization ‘Bevolkingsonderzoek ... dense area and not for other breast cancer risk factors When we only adjusted for age and dense area like Stone did, we observed a weaker effect than Table Combined effect of dense and fat tissue ... breasts having a more ‘supportive’ role than it does in smaller breasts and, therefore, it may be less correlated with the number of epithelial cells at risk and, hence, it is more weakly associated...

Ngày tải lên: 22/03/2014, 17:20

... between risk factors for breast cancer and hormonal status, Int J Epidemiol 1986;15:469-476 Talamini R, La Vecchia C, Franceschi S, et d Reproductive and hormonal factors and breast cancer in a northern ... Menstrual cycle patterns and breast cancer risk factors, Cancer Res 1978;38: 4021-4024 Apter D, Vihko R Early menarche, a risk factor for breast cancer, indicates early onset of ovulatory cycles, J Clin ... history of breast cancer, oral contraceptives consumption and parity Categories are coded 0, 1, 2, and so on b Table Odds ratio (OR) estimatesa by age group, for parity, age at menarche, and...

Ngày tải lên: 28/03/2014, 16:20

... respiratory organs among workers at a nickel refinery in Norway Int J Cancer 1973, 12:32-41 Magnus K, Andersen A, Høgetveit AC: Cancer of respiratory organs among workers at a nickel refinery in Norway ... lung cancer and of nasal cancer in a cohort of 495 workers, all of whom were employed at CC between 1948 and 1962 All 64 cases were first employed before 1957; and the reported SIRs (standardized ... whose report in 1990 [3] concluded that more than one form of nickel can give rise to lung and nasal cancer and that much of the respiratory cancer risk seen among nickel refinery workers could...

Ngày tải lên: 20/06/2014, 00:20

... population Risk assessment models that incorporate both a genetic risk score based on these SNPs and the established risk factors for breast cancer may be useful for identifying high -risk women for targeted ... targeted cancer prevention More genetic risk variants and other risk factors should be well evaluated and incorporated into the risk- predicting models to improve the ability of personalized risk ... Both OR (odds ratio) and AR (absolute risk) were taken as indicators to evaluate the risk model For OR based risk model, two different methods were used One method treated each risk allele/factor...

Ngày tải lên: 21/06/2014, 19:20

... Chapter Risk Factors for Skin Cancer Indoor Tanning: A Bio-Behavioral Risk Factor for Skin Cancer Carolyn J Heckman and Sharon L Manne Chapter UV-Induced Immune Suppression that Promotes Skin Cancer ... suppression that supports tumor development and progression 32 Skin Cancers – Risk Factors, Prevention and Therapy 3.2 UV radiation suppresses anti-tumor immunity and promotes tumor development The ... Indoor Tanning: A Bio-Behavioral Risk Factor for Skin Cancer appearance and that these reactions were important to their self-image (Vannini & McCright, 2004) Additionally, tanning and body dysmorphic...

Ngày tải lên: 27/06/2014, 18:20

... reduction Following RT for HL, breast and lung cancer account for the greatest burden of excess risk [1] The estimated ERRs for radiation-induced breast cancer and lung cancer in never-smokers ... radiation-induced cancer risks is an extension of the standard initiation/inactivation cancer risk model [17] Specifically the standard model predicts essentially zero radiation-related cancer risk at ... [5,8,22,23] and bilateral lung V5 [22] V30 for the whole heart was also calculated [23] Second cancer risk modeling Given a dose-volume histogram (DVH) for a normal tissue organ, and assuming...

Ngày tải lên: 09/08/2014, 10:21

... evaluate the correlation between smoking behaviour and other risk factors and the outcome in patients treated with radiochemotherapy for anal cancer in a single center Methods Between 1990 and 2006 ... radio(chemo)therapy for head and neck cancer They found that smoking was an independent prognostic factor for survival with a relative risk of 2.3 Also the smoking history was identified as additional factor influencing ... other evaluated risk factors, in particular N category and tumor site showed no significant prognostic effect Especially N category is often addressed as a prognostic factor for survival [15,27]...

Ngày tải lên: 09/08/2014, 10:21

... the CYP1A1MspI and exon7 polymorphisms and lung cancer risk We evaluated this risk with regard to combinations of variants (i.e., type B and type C for MspI and Ile/Val and Val/Val for exon 7) versus ... MspI polymorphism and lung cancer risk in 2000, in a meta-analysis performed by Le Marchand L et al [11] included only 11 studies, the exon polymorphism did not correlate with lung cancer risk Shi ... Figure Forest plot (random-effects model) of lung cancer risk associated with CYP1A1 MspI for the combined types B and C vs Type A Each box represents the OR point estimate, and its area is proportional...

Ngày tải lên: 10/08/2014, 10:21

... the American Association for Cancer Research; April 6-10, 2002; San Francisco, California 963, Abstract #4772 16 Morgan AS, Sanderson PE, Borch RF, et al: Tumor efficacy and bone marrow-sparing ... Clinical Practice standards In this phase study, the Sponsor provided a safety monitoring plan for the study and the Sponsor’s safety, pharmacovigilance committee was responsible for the oversight ... evaluated using descriptive statistics in terms of count and percentage for categorical variables and sample size, mean, median, and range for continuous variables Event variables were calculated...

Ngày tải lên: 10/08/2014, 22:20