... (46,47) They are synthesized by chondrocytes and FLS These cytokines act in various ways in the pathogenesis of OA such as inhibition of synthesis of type (articular) cartilage and activation of catabolic ... present clinical study we sought to evaluate the comparative efficacy and tolerability of 5-Loxin® and Aflapin® in the treatment of OA of the knee Materials and Methods Study materials BE-30 (5-Loxin) ... [31] The pain subscale was the average of the first five questions of WOMAC and measured using the NU scale from ('no pain') to 100 ('extreme pain') for each question The stiffness subscale was the...
Ngày tải lên: 25/10/2012, 11:40
... interspersed by a stimulus which deviated from the standard in the intensity of the first component and the glide direction of the second constituent The number of distinct MMN components elicited by ... et al The relationship of age, gender, handedness, and sidedness to the size of the corpus callosum Academic Radiology 1994; 1:243-248 69 Driesen NR, Raz N The influence of sex, age, and handedness ... P300 and the N2b Data indicate that the P300 is involved not only in processes of working memory, but may interact with the N2b in the control of motor response to external cues Through the use of...
Ngày tải lên: 02/11/2012, 11:08
Starch and Protein Quality Requirements of Japanese Alkaline Noodles (Ramen).pdf
... score of 14 points, or 70% of the maximum 20 points allocated for texture, at each of the two times of assessment Total texture score was the sum of the two scores The median score of the four ... for the sample set The PV and BD of the commercial sample assessed in mM AgNO3 were the second lowest and third lowest of the sample set (238 and 125 RVU, respectively) Dough stability of the ... from these analyses and the texture of ramen prepared from the same flours were examined Other analyses included FN tests on the 20 wheat samples, and protein and ash determinations on the flours...
Ngày tải lên: 16/12/2012, 15:25
Teachers’ and teacher evaluators’ perceptions of the current teacher evaluations and teaching assessment criteria
... follow - the objectives are clear and achievable - there is an awareness of student problems - the teacher understands and can explain the plan - the lesson plan shows a good understanding of the ... - the teacher encourages and praises - the teacher considers the feelings of the students Teacher’s manner and use of English excellent very good - The teacher seems relaxed and confident - The ... combination of teaching facilities and equipment well and adequately with the content of the lesson (2 points) Reasonable board presentation, clear handwriting and drawings, clear and standard speech;...
Ngày tải lên: 07/09/2013, 13:45
Tài liệu Đàn tính The Marvelous and Sarced Musical Instrument of the Tay People- La Công ý pptx
... bunch of bananas, some fruit, and flowers—burns incense, reports the new instrument to the founding ancestor of all Then and the ancestors of her line of Then, and recites spells.8 These spells, and ... instrument of the tày people | 283 ment and the position of the Then’s fingers If the Then holds the neck of the đàn tính upright in her right hand, but without playing, she implies that the troops ... covering, and the other ritual equipment The Then follows behind the porter These things must arrive first, in advance of the Then, on the way home as well To pay respect to the sacred đàn tính and...
Ngày tải lên: 10/12/2013, 04:15
Tài liệu THE ELDERLY AND MOBILITY: A REVIEW OF THE LITERATURE pdf
... position of safety: the complex traffic environment at intersections and the range of perceptual and cognitive tasks demanded of drivers, often combined to produce a ‘testing of the limits’ type of ... drive The Group’s summary of age-based mandatory assessment programs was thus: The outcome of such procedures is mixed On the one hand, they reduce the overall exposure of older drivers and therefore ... decreases The number of journeys made for non-work activities remains almost constant to the age of 75 and decreases thereafter, with the length of these journeys also reducing with THE ELDERLY AND...
Ngày tải lên: 13/02/2014, 18:20
Tài liệu Investigation of Organic Chemicals Potentially Responsible for Mortality and Intersex in Fish of the North Fork of the Shenandoah River, Virginia, during Spring of 2007 ppt
... Laboratory Friends of the North Fork of the Shenandoah River Prepared in cooperation with the Friends of the North Fork of the Shenandoah River Open-File Report 2008–1093 U.S Department of the Interior ... cooperation with the Friends of the North Fork of the Shenandoah River (FNFSR), a non-profit organization, conducted this study to identify AOCs in the river water and assess the estrogenicity of the complex ... not known if the trace levels of para-cresol and 17α-ethynylestradiol are the sole causes of the estrogenic response in these samples because of the large numbers of natural and synthetic polar...
Ngày tải lên: 14/02/2014, 08:20
Tài liệu I MMIGRANT S MALL B USINESS OWNERS: A S IGNIFICANT AND G ROWING PART OF THE E CONOMY pdf
... the bottom of the list of immigrant share of population (3 percent) and labor force (4 percent), but is in the top half of the 50 states plus the District of Columbia (at 20th) in the ratio of ... employees What share are these small businesses of the overall economy, and what is the role of immigrants in them? Second and for the larger part of this report—we look at the immigrant small business ... director of the Race, Ethnicity, and the Economy program of the Economic Policy Institute Muzaffar Chishti, director of the Migration Policy Institute’s office at the New York University School of...
Ngày tải lên: 18/02/2014, 00:20
Tài liệu Báo cáo khoa học: Verprolin function in endocytosis and actin organization Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain doc
... expression level of the GFPtagged fusion proteins is indicative of that of the equivalent untagged proteins We examined whether the various charged-to-alanine substitutions affected the ability of full-length ... proteins, but we expect that the relative expression level of the tagged proteins is indicative of that of the equivalent untagged proteins To assess the function of these proteins in endocytosis ... expect that the relative expression level of the GFP-tagged proteins is indicative of that of the equivalent untagged proteins Lipid anchoring of C-Vrp1p bypasses the requirement for the LBD for...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Development of a new method for isolation and long-term culture of organ-specific blood vascular and lymphatic endothelial cells of the mouse pdf
... examine the endothelial cell biology of the mouse, and will accelerate the molecular and cellular analysis of ECs and their heterogeneity in various vascular beds 1994 Construction of the transgene ... signal sequence of the Pgk gene, and a portion of the multiple cloning site of pMCS5 XhoI–EcoRI-digested tsA58T Ag cDNA was blunted and cloned into the SwaI site of pCGX, and the direction was ... has accelerated the understanding of genetic mechanisms of endothelial development and functions However, further analyses of vascular phenotypes in vivo have been hampered by the complicated...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: Mechanism of dihydroneopterin aldolase NMR, equilibrium and transient kinetic studies of the Staphylococcus aureus and Escherichia coli enzymes docx
... by the cleavage of the bond between 1¢ and 2¢ carbons of the substrate The epimerization product is generated by the re-formation of the C–C bond after the reorientation of GA, which exposes the ... addition of the enzyme, and the middle three spectra were obtained 18, 35, and 70 after the addition of the enzyme The top spectrum is that of DHMP for comparison Only the NMR signals of the 2¢ and 3¢ ... to the sizes of the Fig Stopped-flow analysis of the binding of HPO to SaDHNA The concentration of SaDHNA was lM, and the concentrations of HPO were 10, 20, 30, and 40 lM for traces 1, 2, 3, and...
Ngày tải lên: 19/02/2014, 00:20
Tài liệu Báo cáo khoa học: Evidence for interactions between domains of TatA and TatB from mutagenesis of the TatABC subunits of the twin-arginine translocase docx
... in the presence of substrate and a proton motive force [23] On the basis of these studies, it has been proposed that binding of substrate to the TatBC subunits triggers the recruitment of the ... analyzed the effects of substituting groups of basic residues in these regions of TatA and TatB [24] The present study has increased our understanding of this region in two ways First, the removal of ... rearrangements of the TM spans of these subunits It has not been established whether these TM spans simply anchor the amphipathic regions and cytosolic 2272 domains to the membrane, or whether they serve...
Ngày tải lên: 19/02/2014, 17:20
Báo cáo " On equations of motion, boundary conditions and conserved energy-momentum of the rigid string " doc
... boundary of the rectangle Ω The advantage of the form of the variation δS is that it involves the least possible number of derivatives of the variations δxµ The remaining derivatives of δx in formula ... coincidence of the following two mathematical obstacles: the presence of the high derivatives in the Lagrangian , and the fact that the field xµ (τ, σ) is defined on the finite strip σ π , and −∞ ... δq1 δp2 δq2 δp2 δq2 (53) The boundary terms (the last three terms on the right hand side of formula (50)) vanish in the case of closed string In the case of open string they give a non-vanishing...
Ngày tải lên: 05/03/2014, 14:20
Báo cáo khoa họcRe-engineering the discrimination between the oxidized coenzymes NAD+ and NADP+ in clostridial glutamate dehydrogenase and a thorough reappraisal of the coenzyme specificity of the wild-type enzyme docx
... of product before the steady state is reached: the presence or absence of a burst provides information on the position of the ratelimiting step along the reaction pathway, and the amplitude of ... analysis conrmed the identity of the contaminant Comparison with the spectrum of an authentic NAD+ sample revealed total similarity of the fragmentation pattern The negative portion of the spectrum ... (results not shown) The binding of the reduced coenzymes to the active site of clostridial glutamate dehydrogenase is much tighter than the binding of the oxidized coenzyme Together with the initial...
Ngày tải lên: 06/03/2014, 00:20
Báo cáo khoa học: Substrate preference and phosphatidylinositol monophosphate inhibition of the catalytic domain of the Per-Arnt-Sim domain kinase PASKIN ppt
... S6 and the GST-tag (C) Immunoblot analysis of the phosphorylation status of p70S6K and S6 in Paskin+ ⁄ + and Paskin) ⁄ ) MEFs (D) Immunoblot analysis of the phosphorylation status of p70S6K and ... increases cell wall glucan synthesis at the expense of glycogen storage In the absence of PSKs, glycogen rather than glucan is produced, affecting the strength of the cell wall [9] Two independent ... phosphorylation of a microarray of 1176 peptides in the presence of [c-33P]ATP The magnified inset shows an example of the results obtained after detection by phosphorimaging (B) Peptide sequences of the...
Ngày tải lên: 06/03/2014, 00:21
Nutrition and cancer: A review of the evidence for an anti-cancer diet pptx
... cancers of the mouth and pharynx, esophagus, lung, stomach, and colon and rectum; evidence of probable risk reduction was found for cancers of the larynx, pancreas, breast, and bladder [1] Many of the ... adequate The glycemic index is an indication of the blood sugar response of the body to a standardized amount of carbohydrate in a food The glycemic load takes into account the amount of food ... urinary secretion of isothiocyanates, was inversely related to the risk of breast cancer; the quartile with the highest intake only had 50% of the risk of the lowest intake group [89] In the Nurses'...
Ngày tải lên: 06/03/2014, 02:21
CORREGGIO A COLLECTION OF FIFTEEN PICTURES AND A SUPPOSED PORTRAIT OF THE PAINTER, WITH INTRODUCTION AND INTERPRETATION pot
... accompanied by one of the four Fathers of the Church The[ 38] Christian Fathers were the men whose writings and teachings shaped the doctrines of the faith in the early centuries of our era They interpreted ... chin and neck, and the gradation in the shadow cast by the book on the hand, show Correggio's mastery of chiaroscuro [13] III THE MARRIAGE OF ST CATHERINE At the time of her coronation, St Catherine ... scourged him And the soldiers platted a crown of thorns and put it on his head, and they put on him a purple robe, and said, Hail, King of the Jews! and they smote him with their hands Pilate therefore...
Ngày tải lên: 06/03/2014, 13:20
Báo cáo khoa học: Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms docx
... degradation of IGFBP-1 isoforms The y-axis shows the percentage of the ratio between the spot area of the degraded and that of the untreated protein measured using IMAGE J 1.37V software the presence of ... and that the susceptibility to proteolytic degradation of the isoforms increased with the number of phosphates linked to the polypeptide chains The different position of the groups bound to the ... together with identical aliquots of the untreated proteins (Fig 9A) The degradation process was evaluated on the basis of the ratio between the integrated areas of the intact protein in the treated...
Ngày tải lên: 07/03/2014, 00:20
Measuring Changes in Service Costs to Meet the Requirements of the 2002 ppt
... Seattle; and the members of the Office of the Secretary of Defense Integrated Process Team for their thoughts and reactions to an earlier version of this work We also wish to thank our RAND colleagues: ... thought of as the product of the quantity of the service purchased and the price per “unit” of the service, so costs can be reduced either by receiving a better price or by reducing the quantity ... services They may not be available to other branches of the military, but they could be useful for the Air Force Alternatively, the Office of the Secretary of Defense, Program Analysis and Evaluation...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Halogenated benzimidazoles and benzotriazoles as inhibitors of the NTPase/helicase activities of hepatitis C and related viruses ppt
... )70 °C The areas of the gels corresponding to the released strand and to the nonunwound substrate were cut out and 32 P radioactivity counted Alternatively, the films were scanned and the radioactivity ... of 1.5–5.5 lM) of the helicase activities of HCV, WNV and Suv3(D1–159), but not JEV The tetrachlorobenzotriazole TCBT is only a weak inhibitor of the HCV enzyme, and a moderate inhibitor of the ... inhibition of the unwinding reaction by the HCV enzyme was observed when the DNA substrate concentration exceeded 15 pM (not shown) The responses of the helicase activities of the other three...
Ngày tải lên: 08/03/2014, 02:20