development of breast cancer treatment
Tài liệu Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study pdf
... invasive breast cancer by age, history of lobular carcinoma in situ (LCIS), history of atypical hyperplasia, 5-year predicted breast cancer risk, and number of first-degree relatives with breast cancer Patient ... risk for breast cancer because they 1) were 60 years of age or older,2) were 35–59 years of age with a 5-year predicted risk for breast cancer of at least 1.66%, or 3) had a history of lobularcarcinoma ... using combinations of risk factors, was used to esti-mate the probability (risk) of occurrence of breast cancer over time. Results: Tamoxifen reduced the risk of invasive breast cancer by 49% (two-sided...
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Mammography and Beyond: Developing Technologies for the Early Detection of Breast Cancer pptx
... physicalexamination of the breast are now the mainstays for early detection of breast cancer. Screening for early cancer detection has been credited forpart of the recent reduction in breast cancer mortality, ... Detection of Breast Cancer Committee on Technologies for the Early Detection of Breast Cancer Sharyl J. Nass, I. Craig Henderson, and Joyce C. Lashof, EditorsNational Cancer Policy BoardINSTITUTE OF ... devoted to the development and refining of technologiesfor the early detection of breast cancer. The purpose of the study de-scribed in this report was to review the breast cancer detection...
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BREAST CANCER - TREATMENT GUIDELINES FOR PATIENTS potx
... body. Systemic treatment given to patients who have no evi-dence of spread of cancer, but who are at risk of developing spread of the cancer is calledadjuvant therapy. The goal of adjuvant therapyis ... elsewhere.If breast cancer cells have spread to theaxillary lymph nodes, it makes it more likelythat they have spread to other organs of thebody as well. Types of Breast Cancer Breast cancer is ... BisphosphonatesBisphosphonates are used in breast cancer treatment to strengthen bones that have beenweakened by invading breast cancer cells.The most commonly used bisphosphonatesin breast cancer treatment are pamidronateand...
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Management of breast cancer in women: A national clinical guideline ppt
... 28MANAGEMENT OF BREAST CANCER IN WOMEN A Women with breast cancer should be offered audiotapes or follow up summary letters of important consultations. A Clinical encounters with women with breast cancer ... 8MANAGEMENT OF BREAST CANCER IN WOMEN2+ A All women with early stage invasive breast cancer who are candidates for breast conserving surgery should be offered the choice of breast conserving ... measurement of the presence of psychological symptoms in women with breast cancer should be tailored to the individual circumstances of the patient (eg presence of high level of distress...
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Factors infl uencing the risk of breast cancer – established and emerging ppt
... essential for the development of the breast, paradoxically oestrogen is also involved in the development of breast cancer via the stimulation and proliferation of breast cancer cells15,16. ... breast cancer, and as effect modifiers of the association of fat intake and risk of breast cancer. Cancer Causes Control, 8, pp49-56.18 Collaborative Group on Hormonal Factors in Breast Cancer ... The protective role of pregnancy in breast cancer. Breast Cancer Res., 7(3), pp131-42.20 Collaborative Group on Hormonal Factors in Breast Cancer (2002b). Breast cancer and breastfeeding: collaborative...
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Mouse models of breast cancer metastasis: Anna Fantozzi and Gerhard Christofori pdf
... purposes)Available online http:/ /breast- cancer- research.com/content/8/4/212AbstractMetastatic spread of cancer cells is the main cause of death of breast cancer patients, and elucidation of the molecular mecha-nisms ... From genetic abnormality tometastases: murine models of breast cancer and their use inthe development of anticancer therapies. Breast Cancer ResTreat 2005:1-13.19. Aslakson CJ, Miller FR: ... initial spreading of cancer cells to local lymph nodes viathe lymphatics in human breast cancer. Another important aspect to the understanding of breast cancer metastasis is the role of different...
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Detection of breast cancer cells using targeted magnetic nanoparticles and ultra-sensitive magnetic field sensors potx
... ì 104Hathaway et al. Breast Cancer Research 2011, 13:R108http:/ /breast- cancer- research.com/content/13/5/R108Page 11 of 13 IntroductionNew cases of invasive breast cancer were predicted toexceed ... critical to the development of tar-geted nanoparticle cocktails for breast cancer detection aswell as individualized targeted particles for monitoring treatment and metastases in breast cancer patients ... 106),followed by BT-474 breast cancer cells (2.75 ì 106), MCF7 breast cancer cells (0.18 ì 106), and MDA-MB-231 breast cancer cells (0.11 ì 106). TheChinese hamster ovary (non -breast) cell line...
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Guidelines for the early detection and screening of breast cancer ppt
... with the establishment of diagnosis and treatment programmes. 26 Guidelines for the early detection and screening of breast cancer Screening for breast cancer Breast cancer is most easily and ... screening of breast cancer The Regional Office has been proactive in the development, implementation and assessment of regional guidelines for the early detection and screening of breast cancer, ... benefit of an effective breast cancer screening programme is a reduction in breast cancer mortality and an increase in life years of good quality. The cost-effectiveness of a breast cancer screening...
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Guidelines for management of breast cancer ppt
... therapy Management of special problems in breast cancer 37Figure 13. Paget’s disease of the nipple-areola complexFigure 14. Cancer of the male breast: diagnosis Diagnosis of breast cancer 15Prognostic ... systemic treatment, an international overview of treatment outcomes, treatment of early stage invasive breast cancer including surgery, adjuvant therapy for node-negative and node-positive breast cancer, ... patients with node-positive primary breast cancer. Journal of Clinical Oncology, 2003, 21(6):1–9.Hortobagyi GN. Treatment of breast cancer. New England Journal of Medicine 1998, 339:974–984.Hurkmans...
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Reducing the Risk of Breast Cancer With Medicine: A Guide for Women potx
... risk of breast cancer, about half as many (1woman) will get breast cancer. = the number of women whowill get invasive breast cancer without taking medicine (2 out of 100).= the number of women ... Most women will never get breast cancer. n A woman’s risk of breast cancer increases with age.n Two different medicines can lower the risk of some kinds of breast cancer. n Both medicines have ... estrogen, this type of breast cancer cell can’t multiply and grow.Some breast cancers do not have estrogen receptors. This type of breast cancer is called estrogen-receptor negative cancer. It is...
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báo cáo hóa học: " Experimental a-particle radioimmunotherapy of breast cancer using 227Th-labeled p-benzyl-DOTAtrastuzumab" pptx
... from carcinoma of the breast. Clin Orthop 1958, 11:202-216.24. Thorpe PE, Burrows FJ: Antibody-directed targeting of the vasculature of solid tumors. Breast Cancer Research and Treatment 1995, ... Dahle J: Treatment of HER2-expressing breast cancer and ovarian cancer cells with alpha particle-emitting 227Th-trastuzumab. Int J Radiat Oncol Biol Phys2011, 79:563-570.18. Henriksen G, Hoff ... shown).AutoradiographyAutoradiograp hy of SKBR-3 tumor xenografts showedthat the distribution patterns of radioactivity after injec-tion of 600 kBq/kg of 227Th-trastuzumab were inhomo-geneous (Figure 8). The smallest of the...
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Báo cáo hóa học: " A Novel Docetaxel-Loaded Poly (e-Caprolactone)/Pluronic F68 Nanoparticle Overcoming Multidrug Resistance for Breast Cancer Treatment" pot
... considerablepotential for treatment of breast cancer. Keywords Nanoparticles Á MDR Á Pluronic F68 ÁPoly (e-caprolactone) Á Docetaxel Á Breast cancer Introduction Cancer remains the leading cause of death worldwide. ... expression of p27 is a novelmechanism of docetaxel resistance in breast cancer cells. Breast Cancer Res. 6(5), R601–R607 (2004)20. G. Reich, In vitro stability of poly (D, L-lactide) and poly (D,L-lactide)/poloxamer ... detection and screening of breast cancer is associated with less invasive surgicalprocedures and may increase survival, the 5-year survivalrate of metastatic breast cancer (stage IV) is still...
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