developing new treatments based on a better understanding of disease bio

... available data on lipoprotein concentrations and metabolic fluxes Since the model outcomes cannot be measured directly, the only available technical validation was corroboration For an initial ... ratios as predictors of cardiovascular disease in a separate study To this end we will analyze relevant data from cohorts such as the Framingham Heart Study Developing a similar approach to Particle ... indication of clinical usefulness of lipoprotein metabolism ratios based on Particle Profiler Future development We plan to conduct a further clinical validation of Particle Profiler -based metabolic...

Ngày tải lên: 10/08/2014, 09:22

... International Classification of Functioning, Disability and Health and the position of the variables included in the study by Brionez and colleagues [1] AS, ankylosing spondylitis; BASFI, Bath Ankylosing ... Psychological correlates of self-reported functional limitation in patients with ankylosing spondylitis Arthritis Res Ther 2009, 11:R182 Page of International Classification of Functioning, Disability and ... strength of this study is that not just one psychological variable but a broad range of psychological variables, each representing a different construct, were analyzed in one study Each construct considered...

Ngày tải lên: 12/08/2014, 11:22

... by recycling of selected components via vesicular or tubular budding The lower right-hand side of the diagram shows the ‘normal’ maturation pathway of a phagosome containing a non-pathogen, which ... Gotthardt et al [4] made a detailed analysis of six different phagosome maturation stages, differentiating a total of 1,388 phagosome protein spots on two-dimensional gel electrophoresis The analysis ... phagosome actin assembly and maturation leading to killing of pathogenic mycobacteria Nature Cell Biol 2003, 5:793-802 Burlak C, Whitney AR, Mead DJ, Hackstadt T, Deleo FR: Maturation of human neutrophil...

Ngày tải lên: 14/08/2014, 18:20

... better the prevailing conceptualisation of motivation The field of motivation has moved away from a polar high-low conception, to a more multidimensional conceptualization of motivation; where it ... consideration in achievement goal research Understanding Goal Orientations Another contribution of Cho and Sim (2008) is the demonstration that achievement motivation and fear of failure may ... years of education (primary and secondary school), pass is usually associated with an absolute 50 out of 100 marks In Singapore tertiary education, students are graded on a bell curve A grade of...

Ngày tải lên: 16/10/2015, 15:38

... Inflection Sridharan, A and Prakash, K 1995 Discussion on Point Method Geotechnique, 47 (1): 199-200 ‘Limitations of Conventional Analysis of Consolidation Robinson, R.G 1999 Consolidation Analysis ... The actual theoretical one-dimensional consolidation relationship between average degree of consolidation U and the time factor T obtained from the Terzaghi theory may, depending on the range of ... on Results 2007 Diagnostic Curve Methods for Geomechanics, ASCE, (1): 75-79 of One-dimensional Consolidation Tests, Soils and Sivaram, B and Swamee, P.K 1977 A Computational Foundations, Japan,...

Ngày tải lên: 21/03/2013, 14:09

... Lechner G et al, Automotive Transmission, Springer publication,1994 Notations and abbreviations AMT Automated Manual Transmission AT Automatic Transmission CVT Continuously Variable Transmission EFCC ... Method of Optimal Shift Control Based on Pattern Recognition and Learning Algorithm, 4th World Congress on Intelligent Control and Automation, China, 2002 [6] Mashadi B and Kazemkhani A A Fuzzy gear ... to make this approach applicable to conventional transmissions, a many-gear transmission concept has been established Fuel economy and gear shifting effects Many approaches are known as feasible...

Ngày tải lên: 05/09/2013, 17:03

... optical data storage, ultrafast optical communication, as well as biological/chemical sensing and imaging in the visible and infrared spectral regions ) Figure Anisotropic laser emission (a) Variation ... and preparation procedures, optical measurement setups, numerical simulation method, as well as additional experimental data This material is available free of charge via the Internet at http://pubs ... the nanorod axis (the c axis of the wurtzite crystal structure) The measured polarization ratio is 0.3 (b, c) Plots of laser emission at K as a function of the emission polarization angle relative...

Ngày tải lên: 18/09/2013, 21:26

... which has gone on to dilatation and its consequences Nevertheless, in the absence of any statistics to the contrary, I strongly suspect that I am an exceptional case, and my aquatic career was not ... OARS a pretty fair state of health, being able to stand a considerable amount of hard work, in the shape of a 20 or 30 miles walk, or a good long pull on the river." Q also appears to have passed ... remarks : " I feel certain that the Putney race alone would not have brought on the, inflammation that ensued C was a man who had never had any rest from hard training and racing for at least...

Ngày tải lên: 14/02/2014, 21:20

... under a linear gradient of NaCl from to m gave a pure tRNAArg transcript, which was precipitated by addition of ethanol Aminoacylation reaction The aminoacylation reaction of tRNA was measured at ... no means in a conformation that is fit to activate The fact that kcat and Km for tRNAArg in the aminoacylation reaction not change in the Asn106 fi Ala, Gln111 fi Ala and Phe109 fi Ala mutants of S ... form aminoacyl-tRNA In the aminoacylation reaction of class I aaRSs with aminoacyl-AMP, the 2¢-OH group of the ribose of A7 6 tRNA attacks the carbonyl carbon atom of the –Ca–(CO)–O– moiety of aminoacyl-AMP...

Ngày tải lên: 18/02/2014, 11:20

... People’s Daily, one of the most influential newspaper in mainland China It maintains a vast database of news stories, available to search by the public Among other reasons, we chose this website because ... disambiguation methods In Proceedings of the International Conference on Theoretical and Methodological Issues in Machine Translation, pages 101–112 Rada Mihalcea and Dan I Moldovan 1999 An automatic ... signatures from Japanese text In particular cases, where one only cares about translation ambiguity, this technique can work on any language pair Conclusion and Future Work We presented a novel...

Ngày tải lên: 08/03/2014, 04:22

... Ma, Masaki Murata, Hiromi Ozaku, Masao Utiyama, and Hitoshi Isahara 2000 Named entity extraction based on a maximum entropy model and transformation rules (in Japanese) Journal of Natural Language ... Osaka Toyota) because Japanese POS taggers know that TO-YO-TA is an organization name (a kind of proper noun) *:*:location-name, *:*:org-name -> ORGANIZATION,0,0 Since Yokohama Honda and Kyoto Sony ... expression OO-SAKA-SHI-NAI into two words OO-SAKA (= Osaka) and SHINAI (= in the city), but the training data would be tagged as OO-SAKA-SHINAI (= in Osaka City )...

Ngày tải lên: 08/03/2014, 05:20

... (Guatemala), La Liga de la Leche Materna (Honduras), Asociación Hondure a de Lactancia Materna (AHLACMA), CALMA (El Salvador), the Breast Is Best League (Belize), the Ghana Association of Infant ... International, 2000 59 Macro International Haiti demographic and health survey Calverton, Md, USA: Macro International, 2000 60 Macro International Kazakhstan demographic and health survey Calverton, ... evaluación de un programa educativo para mejorar las prácticas de alimentación en niños de a 24 meses de edad en comunidades rurales de Guatemala (Design and evaluation of an educational programme...

Ngày tải lên: 08/03/2014, 23:20

... STM images of the surface following the evaporation of Å of THAP are displayed in Fig 3a and b Each molecule appears as a six-pronged shape with six bright lobes and a dark center The six-pronged ... Leandri, G Le Lay, B Aufray, C Girardeaux, J Avila, M.E Davila, M.C Asensio, C Ottaviani, A Cricenti, Surf Sci 574 (2005) L9 [2] H Sahaf, L Masson, C Leandri, B Auffray, G Le Lay, F Ronci, Appl ... experimental work done by Fang et al and Hacker et al [13,14] as well as the first principle calculations performed by Hermann et al [15] on the adsorption of PQ on Si(0 1), we propose that an interaction...

Ngày tải lên: 16/03/2014, 15:35

... transition networks which represent in an integrated way all syntactic constraints As stated in the introduction, the authors are developing a N.L interface to a relational data base The lexical ... knowledge plays a fundamental role in choosing a particular analysis Milne argues that a one-word lookahead, with the substantial help of semantic information is what is needed to provide a model of N.L ... sex of the department X" A quite different behavior characterizes the at tachment of a role to a verb (a REF node to a REL node via a CONN node); of course, the attachment of a new case cannot...

Ngày tải lên: 18/03/2014, 02:20

... (Zhang et al., 2008) in our current implementation 2.2 The SSG -based Translation Model The translation in our SSG -based translation model can be treated as a SSG derivation A derivation consists ... LSTSSG And the conventional decodings of both FSCFG and LSTSSG are spanbased expansion Thus, it would be a natural way for our SSG -based decoder to conduct a spanbased beam search The search procedure ... derivation consists of a sequence of grammar rule applications To model the derivations as a latent variable, we define the conditional probability distribution over the target translation e and the cor-...

Ngày tải lên: 31/03/2014, 00:20

... MG, Balasubramanian CK, Behrman AL, Kautz SA: Validation of a speed -based classification system using quantitative measures of walking performance poststroke Neurorehabilitation and Neural Repair ... intervention, thanks to its safety and low price, could really have an impact also as a home-rehabilitation treatment for chronic stroke patients Abbreviations ANOVA: analysis of variance; BF: biofeedback; ... effects on cycling and walking ability in chronic stroke patients A case series study was designed and participants were recruited based on a gait pattern classification of a population of 153 chronic...

Ngày tải lên: 19/06/2014, 08:20

... remain on it In fact, the position on the surface of the resonator where the binding takes place is one factor that strongly affects the resonance frequency shift The maximization in mass responsivity ... this article as: Jiang et al.: Mass spectrometry based on a coupled Cooper-pair box and nanomechanical resonator system Nanoscale Research Letters 2011 6:570 Submit your manuscript to a journal and ... capacitance and voltage of the CPB qubit, and CJ is the capacitance of each Josephson junction Displacement (by x) of the NR leads to linear modulation of the capacitance between NR and CPB, Cb(x)...

Ngày tải lên: 20/06/2014, 22:20

... n tasks to n possible candidates on a one-toone basis in an optimal way For this purpose, it has to be taken into account that there are exactly n! ways to assign n tasks to n candidates, and ... costs) The Hungarian mathematicians, D Konig and E Egervary, proposed an alternative to the computation of all possible combinations (which results computational inefficient as n! gets larger, e.g., ... polynomial is out of the scope of this research work) Page of 10 the urban area was utilized for this purpose The time delay and the corresponding average powers in the case of a 12 tap configuration...

Ngày tải lên: 21/06/2014, 00:20

... Production and characterization of thick, thin and ultra-thin chitosan/PEO films Carbohydr Polym 2011, 83:375-382 Yang QB, Li DM, Hong YL: Preparation and characterization of a PAN nanofibre containing ... Boonamnuayvitaya V, Tayamanon C, Sae-Ung S, Tanthapanichakoon W: Synthesis and characterization of porous media produced by a sol-gel method Chem Eng Sci 2006, 61:1686-1691 38 Ichinose I, Kawakami ... supported on natural Mexican zeolite as an antibacterial material Microporous Mesoporous Mater 2000, 39:431-444 Park S-J, Jang Y-S: Preparation and characterization of activated carbon fibers supported...

Ngày tải lên: 21/06/2014, 04:20

... suspension with sonication for 10 The CNT-Nafion solution was placed on the cantilever electrodes, and an AC voltage of MHz and 10 V peak-to-peak was applied The SWNTs and monomers were aligned ... transistors Anal Bioanal Chem 2006, 384:343 Bernards DA, Malliaras GG: Steady-state and transient behavior of organic electrochemical transistors Adv Funct Mater 2007, 17:3538 Lin P, Yan F, Chan HLW: Ion-sensitive ... fabrication process (a) Attraction of the CNT and Nafion molecules between electrodes with an AC electric field; (b) compression of the CNT and Nafion by suspension evaporation; (c) A CNT-Nafion composite...

Ngày tải lên: 21/06/2014, 04:20