... mapping quantitative trait loci in line crosses using flanking markers Heredity 1992, 69:315-324 Visscher PM, Haley CS: Detectionof putative quantitative trait loci in crosses under infinitesimal ... single QTL [24,25] It would be very difficult to detect all types of pleiotropic QTLs in a marker mapping scheme Conclusion The application of a multiple QTL model in real data set is useful in ... Orange Agricultural Institute; 1999 Henderson CR: Application of Linear Models in Animal Breeding Ontario: University of Guelph; 1984 Grignola FE, Zhang Q, Hoeschele I: Mapping linked quantitative...
... two inbred lines The objective of this article was to propose an integrated method using Bayesian inference via MCMC algorithms for the detectionofmultiple QTL with epistasis under the mixed inheritance ... sampling outline is as follows: (a) (b) (c) (d) (e) (f) (g) updating µ using the Gibbs sampler; updating l or m using the RJMCMC algorithm; updating θ using the MH algorithm; updating δ and γ using ... regardless of prior means This indicates that the method is robust, if not perfect, to prior means of QTL number We also checked the in uence of starting values, including the mixing behavior of the...
... optimal size remains at Ω≈103 μm3 for a wide range of signal amplitudes and control parameters, which is of the same order of real living cells in vivo Since the internal noisein living cell systems ... that, near the Hopf bifurcation point, instead of trying to resist the internal molecular noise, living cell systems may have learned to exploit the internal noise to intensively enhance the ability ... the internal noise influence the signal detectionin small systems? In the present article, via the inositol 1,4,5-trisphosphatecalcium cross-coupling (ICC) cell model, we investigated how the internal...
... terminating the option to the expected reward from continuing The main difficulty from the numerical viewpoint lies in the computation of the expected reward conditional on the actual information In ... the termination of the underlying contracts consisting of fixedrate, floating-rate and option legs at some fixed dates Using Monte Carlo Simulation to compute the prices of these exotics will involve ... is a Brownian motion in R Callable Libor exotics is a class of interest rate contracts that allows the termination of the underlying contracts consisting of fixed-rate, floating-rate and option...
... depending on the resource availability – this minimises the risk of saturation while maintaining interactivity Data management remains hidden to users Algorithm The AlignMiner algorithm is outlined ... show that the AlignMiner results seem to be independent of the alignment algorithm used, since the histograms of M-Coffee are almost identical to those of MultAlin in spite of their different ... seed AlignMiner with a MSA generated using their preferred algorithm This finding is in agreement with other algorithms exploiting the information deposited in each column of a MSA [3] In accordance...
... machine learning He represents instances of it as vectors of 35 features These features encode, among other things, information about the parts of speech and lemmata of words in the context of ... was available during training or testing With this setting, the classifier achieved a recall of 55.1%, a precision of 71.9% and a resulting F-measure of 62.4% for the detectionof the class nonreferential ... non-referential it: a machine learning approach incorporating linguistically motivated patterns In Proceedings of the ACL Workshop on Feature Selection for Machine Learning in NLP, Ann Arbor, MI, June...
... showing significant higher in vivo concentrations in most strains of P aeruginosa [18] This biomarker could then be used in the detectionof P aeruginosa in breath, whether or not in combination ... growing P aeruginosa [27,28], its odour increases when adding tryptophan This is because 2-aminoacetophenone is an intermediate in the biosynthetic pathway for quinazolines, a pathway branching ... Steinheim, Germany) were injected using the same GC-MS method to determine the retention indices of the individual compounds using a modified Kovats method [33] Bacterial culturing Sputa were inoculated...
... Role of Cough Officer Screening in Early Detectionof Pulmonary Tuberculosis in Inpatients Thorac Med 2006, 21:321-327 Page of 13 Granich R, Binkin NJ, Jarvis WR, Simone PM, Rieder HL, Espinal ... every morning during patient admission, they recorded all patients who complained of cough, including during the pre-admission period If a patient complained of cough at any other time of day, ... might due to the increased awareness of TB in Stage II (Figure 2), or because of interference of TB diagnosis by other severe symptoms among patients in the ICU during Stage I In fact, our COS...
... responses of the sensor materials were measured in a ¯owing stream of pure air or in 40 ppm NO in air (60:40 mixture from an air cylinder with another cylinder (BOC special gases) containing ca ... hump obtained in XRD) Typically, as seen in the ®gure, a region containing ca Ê 6.93 A inter-planar separation can be visualized It is interesting to note that these defective lines in WO3 are ... increase in temperature of the Ag/Al2O3 bed (production of NO2) results in the increase in NO sensitivity over the WO3 sensor Fig Complex impedance plots of Ag/WO3 (with simulated RC elements) in air...
... Duong Lam project, default parameters: search radius: 20m; minimum number of points inside the moving windows: 5; interpolation method: IDW. DL1 Default DL2 Default, other set of errors DL3 Search radius: 50m DL4 Min. number of searched points: 10 ... radius (or of the minimum number of points inside the search window), the number of correctly and incorrectly detected points is decreasing. This can be explained as a ... Height of surface / Std. deviation Number of data points Spatial distribution of data points Average distance between data points Number of data points with intentional gross error Magnitude of intentional gross errors ...
... heterogeneity of the content of multilocular cells in different regions of a given WAT depot [11] Ten days of cold-exposure increased the number of multilocular cells and induced the expression of UCP1 in ... some of them in both WT and b3KO mice Mice maintained singly housed at 24 °C are under a mild cold stimulus It is interesting to note in the WAT of C57 mice at 24 °C a significant level of expression ... treatment of diet-induced obesity in mice Endocrinology 138, 405–413 19 Ghorbani, M & Himms-Hagen, J (1997) Appearance of brown adipocytes inwhite adipose tissue during CL 316,243-induced reversal of...
... staining was performed: carbol fuchsin 0.3%, slow heating until steaming, rinsing after min, destaining with 25% sulfuric acid, rinsing, counterstaining with methylene blue 0.3% for min, rinsing ... advantageous in this case, its efficacy for TB case finding in patients with HIV co-infection in Laos remains to be determined CONCLUSION Our study, conducted in a population with a low prevalence of HIV/AIDS, ... (case finding or treatment monitoring) were included in the study Where serial sputum specimens were tested, each specimen was individually included in the comparative analysis Sample processing...
... Short-term in vivo inhibition of insulin receptor substrate-1 expression leads to insulin resistence, hyperinsulinemia, and increased adiposity Endocrinology 2005, 146:1428-1437 Hsu SM, Raine L, ... activity index Mayo Clin Proc 1994, 69:409-415 Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal ... at the State University of Campinas, Coloproctology Unit, and at the Cell Signaling Laboratory of the Department of Internal Medicine Page of (model PT 10/35; Brinkmann Instruments, Westbury,...
... finite (but not unique) set of points in the parameter space Individual parameters within this set could have a very large domain, resulting in a large variation within the individual parameter, i.e ... to the matrix X L (L being the iteration number), in the order of the highest to the lowest sensitivity To make the adjustment of the net influence of each of the remaining parameters on the already ... parameter in the bar chart of Figure The first bar represents the actual value of the parameter as determined in [12] The remaining bars represent the estimated values of the corresponding parameter,...
... frequency and waveform of a single-tone sinusoid using an offline-optimized adaptive filter,” in Proceedings of IEEE International Conference on Acoustics, Speech, and Signal Processing (ICASSP ’05), ... that of the IIR notch filter (IIR-ANF, constrained poles and zeros [6]) The noise is cor2 related Gaussian with variance σq = 0.30 and is obtained by filtering whitenoise using a filter having the ... linear combination of noisy sinusoidsIn such case, the correction in the frequency cannot be solved from (25) and (26) Higher-order terms may be required in the series expansion in (26) for...
... Advances in Signal Processing The objective of this paper is to develop a new technique for separating and potentially classifying a number of correlated sources impinging on an array of sensors in ... reaches a minimum in nodes 1 j dominated by source “A.” (e) Same data in (d) based on arranging λ1 in descending order of magnitude This allows identifying a threshold j∗ for λl1 (as indicated ... original linear indexing in the binary tree yields the sets JA = {0, 1, 3, 7, 15, 16} and JB = {4, 8, 10, 17, 18, 21} Examining the tree structure in Figure 9(f) illustrates that the nodes in...
... methods include H E staining and silver staining of the intestinal sections 36 Dong-Kyun Suh et al Fig Section of the ileum from a pig infected with L intracellularis a : Presence of numerous intracellular, ... present in the porcine intestine and feces including swine genomic DNA The number of amplification cycles was one of the important factors for increasing the sensitivity of the PCR assay The increase ... availability of the PCR assay for screening the prevalence of L intracellularis infection in the pig farms Macroscopic Detectionof Lawsonia intracellularis in diagnostic specimens by one-step PCR examination...
... developed in manual Kodak Industrex developer for at 20 °C, fixed for 5-6 in Kodak fixer (20°C) and thoroughly rinsed in running water Histologic sections of buds sampled at the last date of observation ... distinguish between the different kind of buds 10 d later than those from radiographs made of ’fresh’ buds This was probably due to a retraction of the structures during freeze-drying, which induced ... characteristic is of great interest in experiments in which growth phenomena are studied because it allows the repeated observation of a specific organ, thus avoiding the difficulties of sampling homogeneity...
... imaging modality in RA and indicates that MRI is better suited for detection and grading of minor erosive joint changes in RA Competing interests The authors declare that they have no competing interests ... design, acquisition of data, analysis of data and interpretation of data and writing the manuscript AaV: acquisition and analysis of data SJ: interpretation of data and drafting the manuscript ... sensitivity to change of magnetic resonance imaging and radiographic scoring of structural joint damage in rheumatoid arthritis finger, wrist, and toe joints: A comparison of the omeract rheumatoid...
... the next step in understanding pathogenesis and improving survival of osteosarcoma Tumour location in the metaphysis as well as the age of the patients coinciding with the period of rapid body ... to skeletal growth are involved in the pathogenesis of this tumour Table 3: Mean Age of patients with positive staining vs patients with negative staining for receptors of Growth Hormone Figure ... authors investigated somatostatin receptors by virtue of scintigraphy In this study a very high incidence of patients with somatostatin receptors was found (up to 75%) The authors found higher incidence...