detection of calcium release via ryanodine receptors

... rate of release decreased in the presence of 20 lm Gd3+ This concentration of Gd3+ increased the time taken for calcium release without affecting the total amount of calcium released The effect of ... Regulation of the rat sarcoplasmic reticulum calcium release by calcium J Muscle Res Cell Motil 21, 131–138 20 Lai FA & Meissner G (1990) Structure of the calcium release channel of skeletal ... calcium for calcium- binding sites of rabbit sarcoplasmic reticulum 468 ´ ¨ S Sarkozi et al Fig Gadolinium dependence of the ryanodine binding of the channel Ryanodine binding in the presence of 18...

Ngày tải lên: 19/02/2014, 16:20

... a performance which is substantially independent of the energies of the interfering users Soft-In Soft-Output Detection 107 4.2 SISO detection of space-time block coded signals 4.2.1 Introduction ... computational burden 4.4 SISO detection of space-time block coded OFDM signals 4.4.1 Introduction The use of OFDM is often suggested to simplify channel equalization in the presence of appreciable frequency ... at the Department of Information Engineering of the University of Pisa From 1998 to 2001, he held the position of Associate Professor of telecommunications at the University of Modena and Reggio...

Ngày tải lên: 23/06/2014, 00:20

... case of osteosarcoma is expressing somatostatin receptors otherapy and eventually died after year In our retrospective histological study somatostatin receptors were detected Discussion The use of ... growth are involved in the pathogenesis of this tumour Table 3: Mean Age of patients with positive staining vs patients with negative staining for receptors of Growth Hormone Figure Osteosarcoma ... This case of an osteosarcoma had no somatostatin receptors Immunohistochemistry staining with somatostatin did not produce any reaction Patients with Positive staining for receptors of Growth...

Ngày tải lên: 09/08/2014, 07:21

... large inventory of normalized mathematical indexes of abnormality It is the pattern of these mathematical indexes of abnormality, obtained from analysis of multiple cardiac cycles of the resting ... amplitude of ≥2 mm measured from the baseline, occurring two or more times, • a single episode of radical deviation away from the baseline angle of at least 80° with peak amplitude of ≥5 mm measured ... assess the performance of the prediction of stenosis independent of the prevalence of stenosis, the positive and negative likelihood ratios (LR) were calculated [24] A value of p

Ngày tải lên: 03/11/2012, 10:58

... chemicals These strains were kindly supplied by Dr T Nohmi of the National Institute of Health Sciences S9 fraction of phenobarbital/5,6-benzoflabone-pretreated male Sprague-Dawley (SD) rat liver ... We compared the mutagenic activity (shown as the number of revertants per nanomolecule of chemicals, rev./nmol) of YG strains with that of the conventional TA strains as shown in Fig YG1041 showed ... Identification of C8-modified deoxyinosine and N2- and C8-modified deoxyguanosine as major products of the in vivo reaction of N-hydroxy-6-aminochrysene with DNA and the formation of the adducts...

Ngày tải lên: 05/09/2013, 08:40

... may be because of the difference of particle size distribution of the sediment, especially composition of silt and clay The low recovery rate was also because of the inhibition of nucleic acids ... capsid of approximately 25 nm diameter This virus was also used by Gerba et al (1977) for evaluation of the method Recovery rate was evaluated by dividing amount of spiked Poliovirus by amount of ... procedure of Craig et al (2002) with some modifications: mL double-distilled water was used instead of mL 0.1% peptone water; a vortex mixer was used for 15 sec instead of hand - 310 - Journal of Water...

Ngày tải lên: 05/09/2013, 10:15

... (mg/g) a average ± standard deviation of samples However, upon addition of 100 mg/L each of Ca and Mg leaching of As decreased to 24.6 and 23.3 µg/L, respectively Leaching of As was decreased to more ... Concentrations of Ca and Mg Fig 1(a) clearly shows a decrease in the leaching of As with an increase in the added amount of Ca and Mg In the absence of Ca and Mg, leached As was 51.1 µg/L - 331 - Journal of ... Advantec, Japan) for the analysis of As, Fe, Ca, Mg and P contents of the filtrate The amount of Ca and Mg adsorbed per gram of soil was calculated from the difference of Ca and Mg concentration in...

Ngày tải lên: 05/09/2013, 10:15

... periods may result to the development of oseltamivir-resistant influenza viruses Furthermore, Japan is at the top of the list of countries for per capita consumption of Oseltamivir (Soderstrom et al., ... and 200.06, respectively Quantifications of OP, OC and OC-D3 were based on calibration curves from to 1000 ng/L The limit of detection (LOD) and limit of quantification (LOQ) values for OP, OC ... ST-2 from the 34th week of 2009 to the 7th week of 2010 period were obtained from Osaka Prefectural Institute of Public Health (2010) An index value gives the total number of influenza cases (average)...

Ngày tải lên: 05/09/2013, 10:15

Ngày tải lên: 26/10/2013, 17:15

... combination of bands 5, and which is of great efficacy for the aims of our analysis In Figures and the set of bands 5, and are depicted respectively for the month of May 1994 and March 1997 The fusion of ... algorithms for the detection of waste areas using LANDSAT TM images It is worth of noting that the 30 meters spatial resolution of the Landsat-TM sensor makes the process of detecting waste areas ... number of clusters, the Deterministic Annealing algorithm can start with an over-dimensioned number of clusters At high temperatures, all centers collapse to a unique point (the center of mass of...

Ngày tải lên: 16/01/2014, 16:33

... either 100 pg of DENV-1-, ng of DENV-2-, 100 pg of DENV3- or ng of DENV-4-infected C6 ⁄ 36 cells total RNA was used for cocktail PCR The primer cocktail was composed of 100 nm each of 1G1P1, 1G3P6, ... for probes or primers for the detection of that pathogen against that host background It was found that 99.99% of all possible 11-mers, 70% of all 15-mers and 5% of all 18-mers are present in ... characterization of the virus These results provide a demonstration of the high projected sensitivity of human-blind dengue primers and the operation of the primer cocktail strategy for dengue virus detection...

Ngày tải lên: 14/02/2014, 19:20

... the development of variations of the traditional 2D-gel approach, and the application of these has resulted in the identification of potential new biomarkers for early detection of disease Differential ... 70% (107 of 153) of sera from patients with benign disease and PSA levels of >4 ng/ml, and could accurately predict the presence of cancer in 95% of the patients tested, including 18 of 21 men ... the detection of tumour-specific markers The invention of LASER CAPTURE MICRODISSECTION (LCM) greatly improved the specificity of 2D-PAGE for biomarker discovery, as it provided a means of rapidly...

Ngày tải lên: 15/02/2014, 05:20

... total of six zones per patient The upper zones were defined as areas of the lung above the level of the carina; the middle zones as areas between the level of the carina and the origin of the ... identified by MRI The lack of histopathological correlation or microbiological tests of the adenopathies is another important limitation of the study, and MRI in the phase of expiration may show ... radiologists (VS, EBR, both with 10 years of experience in clinical MR imaging and 25 years of experience in chest imaging) The observers were unaware of CT results to avoid interpretation bias...

Ngày tải lên: 15/02/2014, 12:20

... of the increasing mobility of the population, the changing environment, and the biology of bacilli, the prevalence of TB is higher in China Epidemiological studies indicate that only to 10% of ... point of our study was the subdivision of the patient group according to sputum smear test (positive and negative) Our findings provide a better understanding of the genetic diversity of KIR ... the results of a sputum smear test (positive or negative) The average age of the subgroups was the same Blood was collected before the initiation of anti-tuberculosis therapy A total of 110 unrelated...

Ngày tải lên: 15/02/2014, 12:20

... apyrase [5,7] Third, visualization of the release of ATP demonstrates that the velocity of ATP release correlates well with that of the Ca2+ wave in astrocytes [5] All of these findings suggest that ... P2 receptors that produce Ca2+ transients in astrocytes are P2Y1 and P2Y2 receptors, both of which are coupled with Gq–phospholipase C (PLC), and activation of which results in the formation of ... Ins(1,4,5)P3, leading to Ca2+ release from Ca2+ stores (B) Multiple pathways for the release of ATP Hemichannels of connexin or pannexin, maxi-anion channels, P2X7 receptors and Cl) channels are...

Ngày tải lên: 16/02/2014, 09:20

... phosphorylation Moreover, expression of silent mutants of Shc isoforms showed that only p46Shc and p52Shc rescued the effect of the siRNA Overexpression of p66Shc not only failed to rescue Erk ... disruption of cell–cell adhesion remain elusive Tumor metastasis is a multistep process that, in addition to the loss of cell–cell adhesion, involves degradation of the extracellular matrix and release ... these Shc isoforms This creates a binding site for growth factor receptor-binding protein (Grb2) and results in the recruitment of the Grb2–son of sevenless (Sos) complex to the vicinity of Ras,...

Ngày tải lên: 19/02/2014, 05:20

... one of the four binding sites From the change of the unfolding rate constant under extreme conditions of calcium availability, we were able to estimate the contribution of the incorporation of calcium ... mimics calcium effect absence of GdnHCl, the rate constant of unfolding of pWT (k0Ca2+) was 3.01 ± 0.42 · 10)3Æs)1 In the presence of 100 mm CaCl2, where complete saturation of all four calcium- binding ... deceleration of the unfolding process by almost six orders of magnitude after binding of all four calcium ions, corresponding to an increase in Gibbs free energy of activation of unfolding, at 25 °C, of...

Ngày tải lên: 19/02/2014, 17:20

... amplification of the 3¢ end of the b-gal gene The presence of similar amounts of genomic DNA in the reactions was controlled by concomitant addition of primers that amplify a 200 bp region of the RNA ... isolation by FACS of living cells expressing low levels of antigen Discussion The potential of scFvs for demonstrating the presence of targeted protein antigens in the cytoplasm of mammalian cells ... intracellular forms of antigen To analyze how these scFvs linked to EGFP or d1-EGFP behave in case of low and constant expression of b-gal, we took advantage of the availability of two cell lines,...

Ngày tải lên: 19/02/2014, 18:20

... Statistics of the BioScope corpus The 2nd and 3d columns show the total number of cues within the datasets; the 4th and 5th columns show the percentage of negated and speculative sentences 70% of the ... children (starting from the root of the subtree) to the rule pattern subtree Nodes of type *scope* and * match any number of nodes, similar to the semantics of Regex Kleene star (*) Results As ... the rule tree; neighboring identical siblings of type *scope* or * are replaced by a single node of the corresponding type Figure shows an example of this transformation The rule tree pruning...

Ngày tải lên: 20/02/2014, 04:20

... achieved a recall of 55.1%, a precision of 71.9% and a resulting F-measure of 62.4% for the detection of the class nonreferential The overall classification accuracy was 75.1% The advantage of using a ... subject of subj verb prep preposition before indirect object indirect object of verb that it is subject of ind obj obj direct object of verb that it is subject of obj verb verb that it is object of ... parts of speech and lemmata of words in the context of it (obtained automatically) Other features encode the presence or absence of, resp the distance to, certain element sequences indicative of...

Ngày tải lên: 22/02/2014, 02:20