describe the general structure of a computer network

... have proposed a general method for identification of a cellu- lar network structure based on stationary experimental data, which is applicable to a network of generalized modules under the assumption that ... however, only applicable to the case when for each node there are as many parameters as the number of overall network nodes and these parameters do not directly affect the corresponding node. The fundamental ... experimental data containing (partially) cor- rect dynamic pattern changes then we can infer the (partial) interaction structure of the underlying cellular network by integrating the analysis results...

Ngày tải lên: 07/03/2014, 21:20

... Reykjavik, Iceland), and were refined by varying the pH of the buffer and the concentration of the precipi- tant. Prior to data collection, a crystal was transferred into Paratone-N (Hampton Research) ... used as a search model. The cns program [19] was used for refinement against the 20–2.5 A ˚ intensity data. A ran- domly selected portion of the diffraction data (5.0%) was used to calculate the ... that the endo- activity of XEG is primarily attributable to the active site cleft being open at both ends. In the case of Xgh7 4A, the active cleft is open. Although a precise anal- ysis of the...

Ngày tải lên: 23/03/2014, 05:22

... D36N-1 5-CATCCTTCCCTATCTC AACATCCAGCTGGTTTACT-3 D341N-1 5-AAGGGGAGAACTC AACGGAACACCGGAGG-3 D389N 5-CACTCTCGAAGAGTTCATA AACGAAGTGAAGAAGAATCTC-3 5-GAGATTCTTCTTCACTTCGT TTATGAACTCTTCGAGAGTG-3 M. Karlstro ă m ... 5’-CCTGGAGAAATCGATCA TGAGCTTCGCTCAGTCGTG-3’ 5’-CACGACTGAGCGAAGCT CATGATCGATTTCTCCAGG-3’ F205M 5’-AAAAGGTCGACATCTGG ATGGCGACGAAAGACACGATC-3’ 5’-GATCGTGTCTTTCGTCGC CATCCAGATGTCGACCTTTT-3’ D36N ... conformations, the large and the small domains of each homologue were compared separately. The rmsd values between the C a -carbons of the large domain of TmIDH and that of PcIDH and HcIDH were 0.92 A ˚ (using...

Ngày tải lên: 23/03/2014, 10:21

Ngày tải lên: 30/03/2014, 08:20

Ngày tải lên: 31/03/2014, 07:20

Ngày tải lên: 01/04/2014, 12:20

Ngày tải lên: 12/08/2014, 17:20

Ngày tải lên: 07/09/2013, 13:48

... declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative ... declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative imperative declarative declarative ability/neg. ... anaphoric anaphoric anaphoric exophoric anaphoric exophoric anaphoric anaphoric anaphoric anaphoric exophoric anaphoric anaphoric anaphoric anaphoric exophoric anaphoric anaphoric...

Ngày tải lên: 12/02/2014, 20:20

... related by a dyad axis in the crystal, and a mixture of monomeric and dimeric forms in solution [18]. Therefore, the available structural data suggest that the minimal functional unit in the ACMSD enzyme ... model of cerebral malaria, a frequently fatal com- plication of Plasmodium falciparum infection; in the same model, pharmacological reduction of PA levels was demonstrated to correlate with a better ... by a- amino-b-carboxymuconate-e-semialdehyde decarbox- ylase. J Am Chem Soc 129, 9278–9279. 20 Fukuoka SI, Ishiguro K, Yanagihara K, Tanabe A, Egashira Y, Sanada H & Shibata K (2002) Identifica- tion and expression of a cDNA encoding...

Ngày tải lên: 18/02/2014, 06:20

... SPRK also has an aspar- tic acid residue at position at 200, and with the same conformation as in the two other structures, but Asp200 forms a salt bridge to Lys253 (Ala253 and Asn250 in PRK and ... [18]. The biophysical characteri- zation of SPRK did not reveal the classical cold adap- ted features [19], but still initial comparative studies showed that the catalytic turnover was at least ... within a relatively narrow range (pH 5–8) and are often used in the food industry. Alkaline peptidases are generally highly active around pH 10, have broad substrate specificity and are active at...

Ngày tải lên: 19/02/2014, 07:20

... 5Â-aataatccatggggagtaatacttcctggcgta aaagtgaagtcc-3Â and 5Â-attattggatccctattgctggtccgattctgccag-3Â. 3-TPR NlpI primers (residues 62197) were 5Â-aataatccatgg gggcacagcttttatatgagcgcggag-3Â and 5Â-aataatggatcctcactgttc cttatccgatttttcgaagtgc-3Â. ... for the sharp curvature of the array and reduced superhelical pitch, leading to the formation of a globular structure. Helix a Residues Deviation b,c A AB pair W c AB W c AAÂ Rotation d (AB) (A BÂ) Helix ... X12C of the National Synchrotron Light Source. We are grateful for the assistance of Dr Anand Saxena in the use of this beamline. The National Synchrotron Light Source, Brookhaven National Laboratory,...

Ngày tải lên: 07/03/2014, 16:20

... and barley a- amylases are thus also presented. MATERIALS AND METHODS SUMA software: subsite mapping of amylases This software calculates the apparent binding energies on the basis of the measured ... PPA, an a- amylase studied by us earlier. Also an attempt has been made to use this program for subsite mapping of other a- amylases found in the literature. Evaluations of subsite maps of rice and ... data. The program called SUMA (SUbsite Mapping of a- Amylases) is freely available for research and educational purposes via the Internet (E-mail: gyemant@tigris.klte.hu). The advantages of this...

Ngày tải lên: 08/03/2014, 09:20

... Murakawa, M., Takahashi, S., Tsubuki, S., Kawashima, S., Sakamaki, K. & Yonehara, S. (1998) Purification, molecular cloning, and characterization of TRP32, a novel thioredoxin-related mammalian ... hTRXL-N may account for the formation of a monomer, instead of a dimer in the case of TRX. Furthermore, the loss of intermolecular disulfide-bonds and the disbandment of the hydrophobic patch may also ... C-terminal region is rich in acidic amino acids, if it does have some interaction with the N-terminal domain, the mechanism of regulating the catalytic activity may be similar to that of the dimer....

Ngày tải lên: 08/03/2014, 22:20

... on Innovative ap- plications of artificial intelligence, AAAI’97/IAAI’97, pages 598–603. AAAI Press. Michael Collins and Terry Koo. 2005. Discrimina- tive reranking for natural language parsing. ... Processing of the AFNLP, pages 522–530, Suntec, Singapore, Au- gust. Association for Computational Linguistics. Canasai Kruengkrai, Kiyotaka Uchimoto, Jun’ichi Kazama, Yiou Wang, Kentaro Torisawa, and ... 8: The actual output of our parser trained with a fully annotated treebank. the information of the proposed output for the new 1408 tant reason these labels are used is we want to com- pare the...

Ngày tải lên: 17/03/2014, 00:20

... factors : the dispersal of infor- mation and the obscurity of the coding. In ARIANE-78, the lexical data base may reside on much more 50 files, for a given pair of language. This data base ... part of another file, make permutations or transpositions of several parts of a file, and receive suggestions for the translation of a word displayed in a win- dow. Moreover, the system can ... Human Trans- lation (MAHT). The translator is provided with a text editing system, as well as an uncoded dictionary which may be directly accessed on the screen. But the translation is always...

Ngày tải lên: 17/03/2014, 19:21

... compilation ª 2009 FEBS 2831 of the alanine of the AXXCH motif (Ala25) (in green) and the unsaturated vinyl group of the heme (cyan) are separated by 3.41 A ˚ (as compared with a typical thioether ... 72% similarity. The structures are remarkably similar overall, and in the details of the heme attachment and heme position. The rmsd between the structure of C. fasciculata cytochrome c and S. ... Crystallographic data were collected at beamline IO2 at Diamond Light Source, UK, and we acknowledge the support of T. Sorensen at Diamond and A. Labrador at the ESRF, France. References 1 Barker...

Ngày tải lên: 23/03/2014, 04:21

... energy metabolism. Average ranking of saturation parameters according to their impact on the dynamic stability of the network assessed by analysis of the eigenvalues of the resampled Jacobian matrix ... simplified and detailed rate laws (hybrid model, values in bold). The heading designates the type of load parameter varied and the range of variation relative to the normal value of the reference state. ... within the following physiologically feasible ranges: 1 2 k 0 ATPase k ATPase 2k 0 ATPase (small variation of the energetic load) 1 5 k 0 ATPase k ATPase 5k 0 ATPase (large variation of the...

Ngày tải lên: 23/03/2014, 06:20

... as described [8] according to the method of Kunkel et al. [17]. To construct the Y37 4A mutant, the following oligonucleotide was used as a mutagenic primer: 5Â-GATCACACTCTCGCG AAACA AATAATTCATCACCG-3Â. ... III and IV, and seems to act as a ÔdamÕ of the cleft. These four loops of TVA II are superimposed on those of a- amylase (Taka-amylase A) from Aspergillus oryzae (PDB code, 7TAA) [31] and cyclodextrin ... 2692–2695. 19. Kamitori, S., Satou, T., Tonozuka, T., Sakano, Y., Matsuzawa, H. & Okuyama, K. (1995) Crystallization and preliminary X-ray analysis of Thermoactinomyces vulgaris R-47 a- amylase II. J....

Ngày tải lên: 23/03/2014, 12:20