dehydroepiandrosterone in human immunodeficiency virusinfection monitoring and therapy
Báo cáo y học: "Recent key advances in human immunodeficiency virus medicine and implications for Chin" potx
Ngày tải lên :
10/08/2014, 05:21
... prevention such as vaccine and microbicide development, expanding HIV testing and treatment, discovering and developing new ARV drugs, optimizing the ART delivery system, and improving therapy for non-AIDS ... first-line antiretroviral therapy in India Clin Infect Dis 2010, 50:416-425 FDA Approves Expanded Use of ISENTRESS® (raltegravir) in Combination Therapy for Adult Patients with HIV-1 Infection to Include ... treatment, and prevention of HIV-1: evolution of a global pandemic J Clin Invest 2008, 118:1244-1254 49 McIntyre J: Use of antiretrovirals during pregnancy and breastfeeding in low-income and middle-income...
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Báo cáo y học: "Formulation preference, tolerability and quality of life assessment following a switch from lopinavir/ritonavir soft gel capsule to tablet in human immunodeficiency virus-infected patients" pot
Ngày tải lên :
10/08/2014, 05:21
... 0.04), and in HDL of 4.50 mg/dL (p = 0.01) unrelated to lipid-lowering therapy, were observed at week 12 The rea- Intervention At baseline, demographic and clinical laboratory data including fasting ... observed lipid lowering effect is unclear and deserves further evaluation in larger cohorts Finally, the findings of this study should be interpreted in the context of a pilot, single arm study with ... wild-type and resistant HIVstrains [4,5] In clinical practice, it is extensively used in treatment naïve and treatment experienced patients, and it is a recommended first-line drug in treatment...
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Tài liệu Báo cáo khoa học: Role of cleavage and shedding in human thyrotropin receptor function and trafficking pdf
Ngày tải lên :
21/02/2014, 00:20
... measuring the binding of [125I]Streptavidin Specific binding at each point was normalized with reference to specific binding before the incubation at 37 °C (0-min point) to derive the fraction of initial ... (0–60 min) at 37 °C The concentration of the biotinylated Ig remaining on the cell surface was then quantified by measuring the binding of [125I]Streptavidin In the absence of bTSH, a very weak internalization ... Biochrom Bovine thyrotropin hormone (bTSH; IUÆmg)1), 3-iso-butyl-1-methylxanthine (IBMX), gelatin, BSA (bovine serum albumin; fraction V) and monensin were obtained from Sigma 2,2¢-Azine-di(ethylbenzthiazoline...
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Báo cáo Y học: Group IID heparin-binding secretory phospholipase A2 is expressed in human colon carcinoma cells and human mast cells and up-regulated in mouse inflammatory tissues doc
Ngày tải lên :
18/03/2014, 01:20
... cationic amino acid residues in their C-terminal regions [21,22] Since the multiple cationic residues in the corresponding C-terminal portions of mouse and human sPLA2-IIAs and rat and human sPLA2-Vs ... the fifth painting and subjected to RNA extraction Replicate ear sections were fixed by formalin, embedded in paraffin and stained with hematoxylin and eosin to verify the progress of in ammation ... Tokyo, Japan) containing 10% fetal bovine serum [8–12] cDNAs for human and mouse sPLA2s, human cyclooxygenase (COX)-2 and human microsomal prostaglandin E2 (PGE2) synthase (mPGES) and their HEK293...
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TRAFFICKING IN HUMAN BEINGS, ESPECIALLY WOMEN AND CHILDREN, IN AFRICA ppt
Ngày tải lên :
22/03/2014, 15:20
... TRAFFICKING IN HUMAN BEINGS, ESPECIALLY WOMEN AND CHILDREN, IN AFRICA 17 18 TRAFFICKING IN HUMAN BEINGS, ESPECIALLY WOMEN AND CHILDREN, IN AFRICA 2.8 SPECIAL CHALLENGES In analysing and mapping the ... Enhancing cooperation and coordination between relevant Ministries and Agencies in developing anti-trafficking policies and interventions - Developing policy and taking action against trafficking in ... countries of destination and related countries of origin 22 TRAFFICKING IN HUMAN BEINGS, ESPECIALLY WOMEN AND CHILDREN, IN AFRICA TRAFFICKING IN HUMAN BEINGS, ESPECIALLY WOMEN AND CHILDREN, IN AFRICA...
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Stem Cells in Human Reproduction Basic Science and Therapeutic Potential Second Edition pot
Ngày tải lên :
22/03/2014, 20:21
... pivotal role in translation initiation by binding eIF4E and eIF4A, by forming a bridge between the mRNA and the ribosome, and by binding PABPC1 to facilitate translation of poly(A)-containing mRNAs ... stored mRNAs RINGO/Spy protein is absent in the oocyte cytoplasm, while its mRNA is maintained in a dormant state This is achieved by binding of Pumilio-2, an RNA-binding protein initially described ... cyclin B1) in immature Xenopus oocytes are bound by CPEB, which in turn is bound to maskin, which in turn is bound to eIF4E, the cap-binding factor The binding of maskin to eIF4E precludes the binding...
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Báo cáo khoa học: Characterization of sequence variations in human histone H1.2 and H1.4 subtypes pptx
Ngày tải lên :
30/03/2014, 20:20
... variants in human cell lines proteins, we analyzed the two main fractions and obtained from chymotrypsin digestion and RP-HPLC separation (as shown for CCRF-CEM cells in Fig 2) of peaks 3a and 3b ... means of investigating the occurrence of sequence variations within linker histone subtypes from various human tumor cell lines By using HILIC we detected amino acid substitutions in H1.2 and H1.4 ... C-terminal tail and the binding of H1.4 to chromatin, as arginine offers additional hydrogen-bonding abilities to DNA as compared to lysine Lysine 173 in H1.4 is situated in an SPKK motif, one of...
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báo cáo sinh học:" Recent changes in human resources for health and health facilities at the district level in Indonesia: evidence from 3 districts in Java" doc
Ngày tải lên :
18/06/2014, 17:20
... human resources in health is weak and civil service reform has stalled, the central, provincial and district governments appear to be operating independently with respect to human resources in ... between districts with the increase being greatest in Garut District (347) and least in Ciamis District (151) • the increase in numbers was smallest for doctors (6%) and greatest for midwives ... a whole in terms of funding, decentralization, health facilities, sector performance, and the direction in which the sector is heading Clearly any increase in the number of staff also increases...
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Báo cáo sinh học: " Hepatitis C (HCV), hepatitis B (HBV), the human immunodeficiency viruses (HIV), and other viruses that replicate via RNA intermediaries," pdf
Ngày tải lên :
18/06/2014, 22:20
... polymerase interactions predominate, restricting viral replication and mutation, thus maintaining basal output of consensus viral sequences, thus maintaining genotype Immune escape and maximal ... identified mutations within the V1-V3 loop that increased viral replication in a manner independent of nef [77], confirming other work examining HIV Env recombinants [14], and extending earlier work ... protein genes have overlapping open reading frames and significant alterations in envelope and polymerase gene and protein sequences cannot, therefore, occur independently, a genetic nexus again...
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báo cáo hóa học:" Cytokine Profiles in Human Immunodeficiency Virus-Infected Children Treated With Highly Active " pdf
Ngày tải lên :
20/06/2014, 08:20
... HIV-1 infection and were treated with nucleoside reverse transcriptase inhibitors (zidovudine, lamivudine, didanosine, stavudine, and/ or abacavir) plus protease inhibitor (indinavir, nelfinavir, ... radioactive iodine therapy on cytokine production in Graves' disease: transient increases in interleukin-4 (IL-4), IL-6, IL10 and tumour necrosis factor-alpha, with longer term increases in interferon-gamma ... antibody-secreting cells J Immunol Methods 1983, 65:301-309 Jones BM, Liu TF, Wong RWS: Reduced in vitro production of interferon-gamma, interleukin-4 and interleukin-12 and increased production of interleukin-6,...
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Báo cáo hóa học: " Cultivation of GMO in Germany: support of monitoring and coexistence issues by WebGIS technology" doc
Ngày tải lên :
21/06/2014, 06:20
... environmental information, existing monitoring networks related to GMO issues, details on GMO fields and information on protected areas as well as tools for collecting, processing and mapping monitoring ... Monitoring Database” should provide GMO monitoring data and interfaces to existing environmental information systems being of relevance for GMO monitoring issues The WebGIS GMO monitoring is ... were integrated in the WebGIS GMO monitoring: information on the location of faunaflora-habitats (FFH) in the federal state of Brandenburg including a list on protected species [43], data on monitoring...
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Molecular Imaging: An Essential Tool in Preclinical Research, Diagnostic Imaging, and Therapy potx
Ngày tải lên :
29/06/2014, 11:20
... established for investigating protein-protein interactions in cultured cells and several are now being validated for use in living animals, including the two-hybrid system and protein fragment complementation ... separated into discrete DNA-binding and activation domains (Fields and Song 1989) Proteins of interest are expressed as fusions with either a DNA-binding domain (BD) or activation domain (AD), creating ... imaging of protein-protein interactions in vivo by PET and fluorescence imaging, we engineered a fusion reporter gene comprising a mutant herpes simplex virus thymidine kinase Imaging Protein-Protein...
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Báo cáo y học: "Human immunodeficiency virus infection and autoimmune hepatitis during highly active anti-retroviral treatment: a case report and review of the literature" potx
Ngày tải lên :
10/08/2014, 23:21
... hepatitis in patients with HIV infection [2-8] Three had co-infections with hepatitis C virus and were receiving interferon therapy [6-8] and six more had AIH before starting HAART and one pediatric ... immune restoration in patients with HIV infection in the era of HAART Recognizing AIH in the context of immune reconstitution and initiating appropriate therapy can be lifesaving Treatment of these ... manifestations in HIV-1 infected in- patients and literature review Clin Exp Rheumatol 2008, 26:799-806 11 Wanchu A, Sud A, Singh S, Bambery P: Human immunodeficiency virus infection in a patient...
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báo cáo khoa học: " Simultaneous detection of Human Immunodeficiency Virus 1 and Hepatitis B virus infections using a dual-label time-resolved fluorometric assay" potx
Ngày tải lên :
11/08/2014, 00:22
... circles and squares representing data points pertaining to Tb3+ and Eu3+, respectively measurement was determined as shown in Figure 2B In this experiment, chemically biotinylated rHBsAg was immobilized ... problem in multiplexing would be to design an array -in well strategy in which multiple analyte-capturing reagents are spatially isolated in the same well and used in conjunction with a single reporter, ... Vaidya HC, Beatty BG: Eliminating interference from heterophilic antibodies in a two-site immunoassay for creatine kinase MB by using F (ab’)2 conjugate and polyclonal IgG Clin Chem 1992, 38:1737-1742...
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Báo cáo y học: "Effects of PM10 in human peripheral blood monocytes and J774 macrophages" doc
Ngày tải lên :
12/08/2014, 18:21
... contained in 6-well plates Cells were seeded in RPMI medium containing 0.1% BSA and penicillin/streptomycin at a density of × 105 cells/ ml and incubated at 37°C, 5% CO2 for hour before washing ... of actin-binding protein and myosin in neutrophils during chemotaxis and phagocytosis Adv Exp Med Biol 1982, 141:19-28 McCulloch CA, Knowles GC: Deficiencies in collagen phagocytosis by human ... [22] and impaired phagosome-lysosome fusion [23], which may result in a diminished cellular killing and clearance of particles and pathogens from the lung The pro-inflammatory cytokine interleukin...
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Báo cáo y học: "A Functional Role for ADAM10 in Human Immunodeficiency Virus Type-1 Replication" pptx
Ngày tải lên :
13/08/2014, 01:20
... roles for this complex protein The protein has several known extracellular domains, which include a metalloprotease domain, an integrin binding domain, and a cysteine rich region A recent study ... hygromycin, and 1.0 μg/ mL puromycin [75] Rat intestinal epithelial (RIE-1) cells were maintained in DMEM supplemented with 10% FBS, penicillin, and streptomycin Primary R5 viruses HIV-SF162 [76] and ... numerous and diverse cellular proteins via proteolytic cleavage In addition to its metalloprotease domain, it also contains a disintegrin domain, an EGFlike domain, a cysteine-rich domain, a transmembrane...
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Báo cáo y học: " MicroRNA profile changes in human immunodeficiency virus type 1 (HIV-1) seropositive individuals" pot
Ngày tải lên :
13/08/2014, 05:21
... profiles in patients, in stimulated PBMCs, and in virus infected PBMCs The miRNAs differentially expressed in patients, in anti-CD3 treated PBMCs, and in HIV-1 infected PBMC are depicted in three ... and participated in its design and coordination All authors read and approved the final manuscript Materials and methods Patients and cells Normal and human immunodeficiency virus-infected patient ... apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals J Exp Med 1992, 175:331-340 Matskevich AA, Moelling K: Dicer is involved in protection against influenza...
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Role of sonic hedgehog signalling in human embryonic stem cells and its neural derivatives
Ngày tải lên :
11/09/2015, 10:14
... forebrain, midbrain, hindbrain and the spinal cord This figure was reproduced from Epstein et al., 1999 2.4 SHH and neural development During the initial phase of neural induction, the ectoderm is induced ... Immunoflourescent staining of neural stem cell marker Nestin in SHH-CM and Control-CM treated EB Middle panel shows corresponding DAPI nuclear staining in blue and right panel shows corresponding merged ... to work in My AGS seniors: Linda, you’re an angel for reading this manuscript; Sebastian, Dave, Pauline, Sandy, Andy and other seniors for sharing with me your experiences and giving me invaluable...
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Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in human malignancies and potential therapy pdf
Ngày tải lên :
16/02/2014, 14:20
... ⁄ LEDGF-interacting domain linked to DNA-binding domains (AT-hook and MT domain) becomes disconnected from the PHD domains, the FYRN domain, the transactivating domain, the FYRC domain and the ... different signaling pathways, Role of MLL in human malignancies for example, protein kinase C, protein kinase A, RAS ⁄ RAF, WNT-, phosphatidylinositol 3-kinase and Hedgehog, and thus affects ... protein-binding platform for several other proteins to initiate a fundamental cellular process P-TEFb binds to the N-terminal portion of AF4, whereas the C-terminal portion of AF4 confers binding...
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Báo cáo Y học: Monitoring the structural consequences of Phe12 fi D-Phe and Leu15 fi Aib substitution in human/rat corticotropin releasing hormone Implications for design of CRH antagonists pdf
Ngày tải lên :
17/03/2014, 10:20
... data points in the F2 dimension, 16–32 transients and 720–1024 complex increments in the F1 dimension Raw data were multiplied in both dimensions by a pure cosine-squared bell window function and ... studies carried out in 40% TFE in an H2O mixture [38] According to studies of CRH binding to single bilayer egg phosphatidylcholine vesicles, the development of the intramolecular interaction with ... E.B., Insel, T.R., Perrin, M.H., Rivier, J., Vale, W.W & Kuhar, M.J (1985) Differential regulation of corticotropinreleasing factor receptors in anterior and intermediate lobes of pituitary and in...
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