definitions epidemiology and genetics of asthma and copd

... identification and validation of targets for asthma BG is the head of division of Molecular Immunogenetics, IGIB-CSIR, India He has been working on genetic and molecular biology of asthma pathogenesis and ... on the Genetics of Asthma: Genomewide screen and identification of gene-gene interactions for asthma- susceptibility loci in three U.S populations: collaborative study on the genetics of asthma ... Discovering susceptibility genes for asthma and allergy Nat Rev Immunol 2008, 8(3):169-82 Review Anderson GG, Morrison JF: Molecular biology and genetics of allergy and asthma Arch Dis Child 1998, 78(5):488-96...

Ngày tải lên: 13/08/2014, 13:22

... Although asthma and COPD have many risk factors in common and often coexist in clinical settings, and there is some evidence that asthma may be a risk factor for the development of COPD [40], ... asthma diagnosis had COPD diagnosis, and 21% of those with asthma diagnosis had chronic bronchitis symptoms Total n Asthma diagnosis n (%) Asthma diagnosis Asthma symptoms COPD diagnosis Chronic ... Restriction of analysis to asthmatics without COPD, and to those with COPD without asthma, was performed for both diagnoses and symptoms The results showed similar effects in the restricted and nonrestricted...

Ngày tải lên: 06/03/2014, 19:20

... Tentative Schedule of Visit Description of the research aspects of the study Genetics and testicular cancer education Signing the informed consent document, ... U.S Department of Energy Human Genome Program http://www.ornl.gov/hgmis Where are the genes located? Our bodies are composed of organs and tissues Organs and tissues are made up of many cells ... mutation : Half (50%) of their sons will inherit the mutation and be at increased risk of developing testicular cancer; Half (50%) of their daughters will inherit the mutation, and they will be carriers...

Ngày tải lên: 28/03/2014, 23:20

... among COPD, asthma, and rhinitis Persons with COPD and another condition were classified as having COPD Persons with asthma and rhinitis were classified as having asthma The overall rate of completion ... aged 55 to 75 Of these, 352 reported a physician diagnosis with one of the conditions within the overall rubric of COPD and 122 reported a physician diagnosis of asthma In the course of administering ... and lung cancer in the absence of COPD, asthma, and rhinitis were excluded from the analysis due to small numbers We tabulated the work history and current employment status of persons with COPD, ...

Ngày tải lên: 20/06/2014, 00:20

... comorbidity, and study centre Stratified analyses were performed with respect to diagnosis (neither asthma nor COPD; and asthma and/ or COPD) Respiratory symptoms often occur together, causing problems of ... Netherlands showed that knowledge about both asthma and COPD was related to better adaptation to these diseases [33] Knowledge of disease is likely to vary in the group of asthma and/ or COPD in ... breathlessness without asthma and/ or COPD had lower both PCS and MCS than subjects with asthma and/ or COPD It could be that breathlessness indicated by subjects without asthma or COPD represents a...

Ngày tải lên: 20/06/2014, 16:20

... lengthening of existing vessels, and sprouting and formation of new vessels Lee et al [57] found that levels of VEGF and MMP-9 were significantly higher in the sputum of patients with asthma than ... with asthma and COPD using a high-magnification bronchovideoscope and did not find any difference between COPD patients and controls [43] A drawback of this technique is the detection limit of ... [72] Hypertrophy and hyperplasia of mucous glandular structures and loss of alveolar attachments are considered to be the main structural changes of airway remodelling in COPD and they may play...

Ngày tải lên: 12/08/2014, 11:22

... (HC), asthma, COPD and cold Comparison of pH in EBC obtained by either RTube or ECoComparison of pH in EBC obtained by either RTube or ECoScreen in healthy controls (HC), asthma, COPD and cold ... degasification of EBC prior to analysis, or the use of a special gas [5] We included stable asthmatics and COPD GOLD stage and Comparing the asthmatic and COPD patients with healthy controls, we did ... comparison of two commercial devices in healthy controls and patients with asthma, COPD and colds regarding the measurement of pH, including degasification with argon, and showing a small interday and...

Ngày tải lên: 12/08/2014, 14:20

... history of allergic diseases The diagnosis was based on a clear-cut history of asthmatic symptoms; the use of anti-asthmatic medication and the presence of bronchial hyper-reactivity The antiasthmatic ... disease and asthma Genes Immun 2005, 6:225-30 The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee: Worldwide variation in prevalence of symptoms of asthma, ... asthma is much more often allergic than asthma in adults Thus it might not be surprising that the genetic background of asthma differs between adults and children [23] Furthermore, the size of...

Ngày tải lên: 13/08/2014, 13:22

... HCC [3], and 500, 000 to 1.2 million people die of HBV infection annually [4,5] Because of the high HBV-related morbidity and mortality, the global disease burden of HB is substantial Epidemiology ... increased risk of HBV infection include duration of sexual activity, number of sexual partners, history of sexual transmitted disease, and positive serology for syphilis Sexual partners of injection ... region of genotype C in China [34] Accumulated data suggest the importance of genotype, subgroup and recombination that may influence the biological characteristics of virus and clinical outcome of...

Ngày tải lên: 02/11/2012, 11:12

Ngày tải lên: 03/11/2012, 11:11

... KAR, et al HAND, FOOT AND MOUTH DISEASE ABSTRACT Objective: To describe the epidemiology and clinical features of cases in a outbreak of Hand, Foot and Mouth Disease (HFMD) Design: ... JUNE 10, 2012 [E-PUB AHEAD OF PRINT] KAR, et al HAND, FOOT AND MOUTH DISEASE eosinophilia and two cases with neutrophilia Routine and microscopic examination of stool and urine samples did not ... [E-PUB AHEAD OF PRINT] KAR, et al HAND, FOOT AND MOUTH DISEASE Fig 1.Papulovesicular lesions on the buttocks Fig 2.Papulovesicular lesions on the dorsum of hand with involvement of margins of fingers...

Ngày tải lên: 05/03/2014, 12:20

... Pathophysiology and Pathogenesis of Asthma, and Natural History of Asthma 11 Key Points: Definition, Pathophysiology and Pathogenesis of Asthma, and Natural History of Asthma ... Pathophysiology and Pathogenesis of Asthma, and Natural History of Asthma; Section 3—The Four Components of Asthma Management; Section 4—Managing Asthma Long Term; and Section 5—Managing Exacerbations of Asthma ... Pathogenesis of Asthma, and Natural History of Asthma SECTION 2, DEFINITION, PATHOPHYSIOLOGY AND PATHOGENESIS OF ASTHMA, AND NATURAL HISTORY OF ASTHMA KEY POINTS: DEFINITION, PATHOPHYSIOLOGY AND PATHOGENESIS...

Ngày tải lên: 17/03/2014, 15:20

... presentation of acute exacerbations of asthma and COPD in a typical emergency department setting, both in disease severity and the treatment required However, the relationship between dose and plasma/serum ... exacerbations of asthma and/ or COPD are usually heavily reliant on short-acting b2-agonists for symptom relief prior to presentation and would be expected to use much higher doses of albuterol ... only used as an estimation of the number of doses of albuterol required during the asthma exacerbation (between different dosage forms), and does not represent the amount of albuterol being delivered...

Ngày tải lên: 21/06/2014, 03:20

... mechanisms and trade-offs Finding mechanisms that explain the difference in life span between males and females is hindered by our lack of understanding of the basic mechanisms of aging and underlying ... Mechanistic explanations often involve the concept of trade-offs, that is, the allocation of energy or other ‘resources’ to functions such as reproduction and behavior, at the expense of somatic maintenance ... amounts of inbreeding had mothers of the same genotype, thus separating the effects of cytoplasmic factors such as mitochondria and maternally contributed gene products from the effects of inbreeding...

Ngày tải lên: 06/08/2014, 19:20

... forests In: FT (1987) Genetic structure and the conservation of California’s endemic and near endemic conifers In: Conservation and Management of Rare and Endangered Plants (Elias TS, ed) California ... maintenance of seedbanks and provenance tests past the tenure of the scientists who initiated them Howard Kriebel provided cases in point With the exception of his provenance test of red oak (Quercus ... United States; Scott Pauley established a test of northern red oak and Roland Schoenike established a test of southern red oak Both were lost when Pauley and Schoenike died When a scientist in the...

Ngày tải lên: 08/08/2014, 19:21

... rhinitis, and eczema.26 Shamssain and Shamsian, assessing 3,000 adolescents aged 13 to 14 years in Sunderland, England, verified the concomitance of asthma, rhinitis, and eczema in 5.1% of subjects.19 ... influence the estimation of prevalence rates of asthma and asthma- like symptoms Eur Respir J 1995;8:53s 13 Pearce N, Weiland S, Keil U, et al Self-reported prevalence of asthma symptoms in children ... al Questionnaire study of effect of sex and age on the prevalence of wheeze and asthma in adolescence BMJ 1998;316:1945–6 Solé D, Camelo-Nunes IC, Wandalsen GF, et al Is asthma in Brazilian children...

Ngày tải lên: 08/08/2014, 21:20

... diagnosis of asthma (OR 2.04), wheeze, and asthma medication use (OR 2.83) but not for AHR, atopy, or airflow obstruction.23 Despite more symptoms consistent with asthma and use of more asthma medications ... relationship and understand the causal mechanisms of obesity and asthma association From a public health standpoint, these studies have substantial implications If asthma were added to the list of conditions ... unit of increased BMI Table Demographics of Total Evaluated and Included Patients Characteristics Number of subjects evaluated Number of subjects included Number of subjects excluded Reasons of...

Ngày tải lên: 08/08/2014, 21:20

... expression of an underlying unobservable continuous variable directly Within this general framework, knowledge of the value of normal probability if often required and consequently the scope of corresponding ... computation of n B different probabilities (which are integrals of dimension n) and their deriva; (r = - &dquo; II /./ II B.=i 1)l tives - - Selection often involves a limited number of candidates, ... account the normality of the distribution : A review of the of general (1941) [Computation of sums of convergent tetrachoric series] IMPSON (1972) [Dimension reduction and repeated S quadratures]...

Ngày tải lên: 09/08/2014, 22:22

... & BURNS, 1981) and ultimately the phenotype and fitness of individuals The study of metabolically related enzymes has likely potential in detecting and understanding epistasis and the forces ... a greater understanding of how selection might work on such loci and of the causal basis behind environmental correlations is required The presence of nonrandom association of the alleles at ... grouped according to the type of fruit trees in the immediate vicinity of each trap : apple (traps C, D and H), cherry (traps A, B, E, I, J, K and N) and peach (traps G, L, M and Q) (tabl 2) Plum trees...

Ngày tải lên: 09/08/2014, 22:23

... frequencies at Mdh-3 and 4, and the small Owing size of Orne sample, we did not test this hypothesis of mixed stocks C Origin of hatchery strains and management implications As 70 p 100 of the hatchery ... sympatric populations of brown trout (Salmo trutta) Genetics, 92, 247-262 YMAN R N., S G., 1981 Genetic perspectives of the identifications and conservation TAHL of Scandinavian stocks of fish Can J ... populations Genetics, 96, 721-726 CROSS T.F., 1982 Biochemical genetics, Section E Annual Report of the Salmon Research Trust of Ireland, 27, 59-60 ROZIER C W.W., 1983 Population biology of Lough...

Ngày tải lên: 09/08/2014, 22:23