death as a universal trigger

... immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART) Blood 2000, 95:249-255 Brenchley JM, Paiardini M, Knox KS, Asher AI, Cervasi ... artificially increasing the death of activated CD4+ T cells does not, on its own, seem to have any impact on CD4+ T cell compartment homeostasis However, this may, at least in part, reflect a ... suggesting that microbial trans­ location may not be the cause of general immune activation However, further analysis is warranted before a role for microbial translocation on T cell dynamics can be...

Ngày tải lên: 06/08/2014, 19:21

... macroevolutionary time at an accelerating pace [1], it appears that living matter as a whole grows by extracting and assimilating electrons and protons from nonliving matter at an accelerating rate If we assume ... peroxidase [72], pyruvate formate lyase, glycerol dehydratase, and benzyl-succinate synthase [119] Because any metabolic conversion catalyzed by an enzyme is a segment of a metabolic pathway, which ... upon and depends upon the adaptability of its individual parts and that the adaptations of a part or the whole invariably involve local or global organizational relaxation and restructuring, caused...

Ngày tải lên: 13/08/2014, 16:20

... strains expressing H5 epitopes 162 xvii ABBREVIATIONS aa Amino acid AC Adenylate cyclase ACE 3-amino-9-ethyl-carbazole ACT Adenylate cyclase toxin ADCC Antibody-Dependent Cellular Cytoxicity ADP ... particular, the universal influenza vaccine candidate M2e was expressed in BPZE1 as a FHA-(M2e)3 chimera and the nasal administration of the recombinant BPLR3 bacteria triggered significant production ... Cytoxicity ADP Adenosine diphosphate AMs Alveolar macrophages Amp Ampicillin APS Ammonium persulphate APC Antigen-presenting cell BALFs Broncho-alveolar lavages fluids BALT Bronchial-associated lymphoid...

Ngày tải lên: 11/09/2015, 10:00

... signals does FADD relocalize to the cytoplasm, promoting CD95–FADD association, which in turn leads to DISC assembly, caspase-8 activation, and apoptotic cell death In addition, nuclear FADD may ... between the nucleus and the cytoplasm Whereas cytoplasmic TRADD mediates apoptosis through FADD and caspase-8 activation, nuclear TRADD acts through a mitochondrial apoptosis pathway [28] Our study ... nuclear FADD and its nuclear–cytoplasmic translocation? Functional DISC assembly and activation of caspase-8 is generally considered to be a ‘point of no return’ in the apoptotic signaling cascade...

Ngày tải lên: 07/03/2014, 02:20

... mutant BCR–ABL tyrosine kinase activates several signalling pathways, including the ERK1 ⁄ pathway, the PKB pathway and the Janus kinase ⁄ signal transducer and activator of transcription (JAK-STAT) ... protein kinase ⁄ extracellular signal-regulated kinase kinase ⁄ kinases: mechanism of action in vivo, pharmacokinetic ⁄ pharmacodynamic relationship, and potential for combination in preclinical models ... pathway modulated by cytokines Cancer Biol Ther 6, 912–919 66 Kuroda J, Kimura S, Strasser A, Andreef A, O’Reilly LA, Ashihara E, Kamitsuji Y, Yokota A, Kawata E, Takeuchi M et al (2007) Apoptosis-based...

Ngày tải lên: 16/03/2014, 00:20

... early after receptor ligation whereas the cell death regulators FAS-associated via death domain (FADD) and caspase are recruited to a pro-apoptotic complex that forms slowly in the cytoplasm This ... necrosis mediated by tumor necrosis factor J Exp Med 187, 1477–1485 62 Sasazuki T, Okazaki T, Tada K, Sakon-Komazawa S, Katano M, Tanaka M, Yagita H, Okumura K, Tominaga N, Hayashizaki Y et al (2004) ... ubiquitinated it does not associate with caspase 8, whereas when it is not ubiquitinated, it rapidly associates with caspase to trigger apoptosis Moreover, blockade of the E3 ligase activity of TRAF2...

Ngày tải lên: 28/03/2014, 23:20

... assessing the translational potential of ideas that are still in the percolation phase The NIH intramural program is an ideal test site for such new translational research approaches, percubator ... MRE-B is a translational researcher who has participated in many laboratory and clinical research studies, as well as several successful biotechnology company start-ups, both privately and in his ... intramural program is often close to impermeable In contrast, universities and many research institutions contain a semi-permeable barrier that allows academic investigators to work in both arenas,...

Ngày tải lên: 18/06/2014, 19:20

... assessing the translational potential of ideas that are still in the percolation phase The NIH intramural program is an ideal test site for such new translational research approaches, percubator ... MRE-B is a translational researcher who has participated in many laboratory and clinical research studies, as well as several successful biotechnology company start-ups, both privately and in his ... intramural program is often close to impermeable In contrast, universities and many research institutions contain a semi-permeable barrier that allows academic investigators to work in both arenas,...

Ngày tải lên: 20/06/2014, 03:20

... was calculated as 32% on a cardiac catheterization and 40% on a transthoracic echocardiogram Shortly after cardiac catheterization, she developed bilateral ophthalmoparesis, significant bulbar ... microcirculation of the heart, and elevated catecholamine states [4,7] TC has been described in many different stressful and catastrophic circumstances such as car accidents, family deaths, and even major ... down-regulate the inflammatory cascades and maintain homeostasis In chronic stress conditions such as autoimmune disease, however, there is a disturbance in this normal homeostatic regulation, as chronic...

Ngày tải lên: 11/08/2014, 02:22

... beginning with half a gram once a week; six months later his dose had increased to a gram a day By then he was shooting up daily He had never had any physical illness Once he was http://www.harmreductionjournal.com/content/2/1/11 ... http://www.harmreductionjournal.com/content/2/1/11 Figure withoutconcentration levels in a case A after conditioning in an accustomed place (A1 ) and in a new place (A2 ), and in a case B Heroin ... Heroin concentration levels in a case A after conditioning in an accustomed place (A1 ) and in a new place (A2 ), and in a case B without conditioning have the opportunity for secondary conditioning...

Ngày tải lên: 11/08/2014, 20:20

... Care Medicine (Société de Réanimation de Langue Française, SRLF) [8] These recommendations are based on plasma Hb concentration and associated clinical state (Table  1), and apart from in cardiac ... 7th and the 72nd hour, mean ScvO2 was higher, mean arterial pH was higher, and plasma lactate levels and base excess were lower in patients who received early goal-directed therapy Organ failure ... Accordingly, increase in the P300 latency above a certain threshold may serve as a monitor of inadequate cerebral oxygenation and as an organ-specific transfusion trigger in the future Spahn and...

Ngày tải lên: 13/08/2014, 20:21

... Kato M, Arakawa H, Sotomatsu M, Kataoka S, Asami K, Hasegawa D, Kosaka Y, Sano K, Igarashi N, Maruhashi K, Ichimi R, Kawasaki H, Maeda N, Tanizawa A, Arai K, Abe T, Hisakawa H, Miyashita H, Henter ... 38 Imashuku S, Kuriyama K, Sakai R, Nakao Y, Masuda S, Yasuda N, Kawano F, Yakushijin K, Miyagawa A, Nakao T, Teramura T, Tabata Y, Morimoto A, Hibi S: Treatment of Epstein-Barr virus-associated ... renal replacement therapy Antiviral treatment and virus shedding Oseltamivir was used as antiviral treatment in 24 patients (96%) for a median of days (IQR, to 10 days), and zanamivir was used as...

Ngày tải lên: 14/08/2014, 07:21

... packages có tên samba rpm –qa samba* => liệt kê packages có tên bắt đầu samba rpm –qa | grep samba => liệt kê packages có tên ch a samba rpm –qd samba => liệt kê files tài liệu liên quan đến samba ... a Cao, Q.1, TP.HCM Tel: (84-8) 38244041 – 0989012418 www.athena.edu.vn - Bạn liệt kê danh sách packages cài đặt (Installed packages) danh sách packages dùng cho bạn download (Available packages) ... (configuration) liệt kê tập tin cấu hình package 3/ Gở bỏ package (Erase): Chú ý: Nếu gỡ bỏ package mà package phụ thuộc vào package khác gỡ bỏ ta dùng thêm tuỳ chọn nodeps  Lỗi package samba-3.0.23c-2.rpm...

Ngày tải lên: 13/09/2012, 10:21

Ngày tải lên: 04/10/2012, 10:24

... Cochran-Armitage trend test was performed in order to test if a gradual increase in sickness absence was associated with increase in risk of disability pension The SAS procedure PROC GENMOD (SAS ... than days of absence per annum decreased from 2.77 to 2.68, and remained significant There was an increased risk of disability pension for people who were smokers at baseline, whereas there was ... was stronger among men (OR=3.13) than among women (OR=2.19) (Table 2) Additional analysis treating days of sickness absence during 1990 as a continuous variable showed a clear trend of increase...

Ngày tải lên: 26/10/2012, 10:03

... mammalian hosts These animals, usually pigs, act as a transformer or converters; creating a strain that can more readily infect humans Pigs can be infected with both avian and human influenza A ... horses, seals, whales, and many types of birds as well as humans This can be a trans-species virus Type B infects only humans [8] Animals act as reservoirs for this influenza virus and Gelbalt [7] ... as a protease to cleave HA which creates a systemic infection as well [1] Taubenberger [1] reported that this transformation was not observed in the1918 strain, or in strains “captured” in nature...

Ngày tải lên: 02/11/2012, 11:12

... straight away without stopping at a petrol station After having talked and talked and talked, and when I finally managed to dismiss her with fake half-promises and sat back into my car at last ... I knew it wasn’t so A more ominous explanation came to my mind Maybe everything was real, and it was taken for granted that I was dead, just I wasn’t! My brain was still working, and I would ... body Admiration and even something like awe Was he awed because she was dead, by the mystery of death? No, he was awed because in his eyes she was beautiful, a beautiful young woman… For a split...

Ngày tải lên: 07/11/2012, 09:08

... 2005), he also makes a distinction between task-based teaching and tasksupported teaching The task-based teaching occurs when the teaching is based exclusively on meaning-focus tasks, and the task-supported ... functions and language notions are taught to learners at the same time with the assumption that language learning relates to learning formulaic expressions of language as well as learning rules of language ... II.1 A review of language teaching approaches Teaching language has received much focus for the past few decades So many approaches and methods such as Audiolingual Method, Total Physical Response,...

Ngày tải lên: 07/11/2012, 14:44

... pleasantness ratings, the aroma concentration had a similar effect on both age groups in the first tasting session: the heightened aroma sample was rated as less pleasant than the regular aroma sample ... Preliminary data analysis revealed no significant main effects and only one significant interaction of day and aroma on the pleasantness ratings of the young, implicating an increase in pleasantness ... a small food reward after the last evaluation session Samples The sample material was a fermented oat bran product (Yosaw, Bioferme, Finland), which is a cereal-based snack food similar to flavored...

Ngày tải lên: 03/04/2013, 21:06

... BA R = B B A where AUC is the area under the curve Statistical analysis All data are presented as a mean value with its standard deviation indicated (mean ± SD) Statistical analysis was conducted ... (Mw = 200,000) was purchased from Hayashibara (Tokyo, Japan) Epirubicin·HCl (EPI·HCl) was purchased from Hisun Pharmaceutical Co (Zhejiang, China) Poly (vinyl alcohol) (PVA) with an average molecular weight ... main pharmacokinetic parameters were calculated by DAS 1.0 (Anhui, China) program Bioavailability (BA) is a measurement of the rate and extent of a therapeutically active drug that reaches the...

Ngày tải lên: 23/04/2013, 21:38